DE60112431D1 - Verwendung von biguanidederivaten zur herstellung eines vernarbungsfördernden medikaments - Google Patents

Verwendung von biguanidederivaten zur herstellung eines vernarbungsfördernden medikaments

Info

Publication number
DE60112431D1
DE60112431D1 DE60112431T DE60112431T DE60112431D1 DE 60112431 D1 DE60112431 D1 DE 60112431D1 DE 60112431 T DE60112431 T DE 60112431T DE 60112431 T DE60112431 T DE 60112431T DE 60112431 D1 DE60112431 D1 DE 60112431D1
Authority
DE
Germany
Prior art keywords
preparation
treatment
biguanide derivatives
driving medicament
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60112431T
Other languages
English (en)
Other versions
DE60112431T2 (de
Inventor
Jean-Paul Potier
Nobumichi-Andre Sasaki
Conception Achab
Gisele Franck
Claude Thal
Joanna Bakala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8850685&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60112431(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE60112431D1 publication Critical patent/DE60112431D1/de
Publication of DE60112431T2 publication Critical patent/DE60112431T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
DE60112431T 2000-05-26 2001-05-23 Verwendung von biguanidederivaten zur herstellung eines vernarbungsfördernden medikaments Expired - Lifetime DE60112431T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0006798 2000-05-26
FR0006798A FR2809310B1 (fr) 2000-05-26 2000-05-26 Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
PCT/FR2001/001598 WO2001091696A2 (fr) 2000-05-26 2001-05-23 Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant

Publications (2)

Publication Number Publication Date
DE60112431D1 true DE60112431D1 (de) 2005-09-08
DE60112431T2 DE60112431T2 (de) 2006-06-01

Family

ID=8850685

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60112431T Expired - Lifetime DE60112431T2 (de) 2000-05-26 2001-05-23 Verwendung von biguanidederivaten zur herstellung eines vernarbungsfördernden medikaments

Country Status (25)

Country Link
US (1) US7199159B2 (de)
EP (1) EP1283708B1 (de)
JP (1) JP4987209B2 (de)
KR (1) KR20030029050A (de)
CN (1) CN100420439C (de)
AR (1) AR032617A1 (de)
AT (1) ATE300942T1 (de)
AU (2) AU6401101A (de)
BG (1) BG65847B1 (de)
BR (1) BRPI0111142C1 (de)
CA (1) CA2410025C (de)
DE (1) DE60112431T2 (de)
DK (1) DK1283708T3 (de)
EC (1) ECSP024359A (de)
EE (1) EE05393B1 (de)
ES (1) ES2244625T3 (de)
FR (1) FR2809310B1 (de)
HU (1) HU229205B1 (de)
MX (1) MXPA02011622A (de)
MY (1) MY137468A (de)
NO (1) NO20025635L (de)
PT (1) PT1283708E (de)
SK (1) SK287249B6 (de)
UA (1) UA76415C2 (de)
WO (1) WO2001091696A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2858232B1 (fr) * 2003-07-29 2006-03-03 Pierre Potier Utilisation d'un derive de biguanide pour proteger la peau des radiations uvb
DE102004022645A1 (de) * 2004-05-07 2005-12-15 Resorba Wundversorgung Gmbh & Co. Kg Bioresorbierbares Material auf Kollagen-Basis
JP4877456B2 (ja) * 2005-04-14 2012-02-15 株式会社 メドレックス ビグアナイド系薬剤を含有するゼリー製剤
KR100926417B1 (ko) 2007-01-29 2009-11-12 한올제약주식회사 Ｎ,ｎ―디메틸 이미도디카르본이미딕 디아미드의 초산염,그의 제조방법 및 그를 포함하는 약제학적 조성물
US20100055142A1 (en) * 2008-08-28 2010-03-04 Tyco Healthcare Group Lp Carrier Neutralization/Modification in Antimicrobial Compositions, Articles and Methods
WO2011083998A2 (ko) 2010-01-06 2011-07-14 한올바이오파마주식회사 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물
US10279007B2 (en) 2010-11-15 2019-05-07 Oxygenetix Institute, Inc. Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs
DE212011100215U1 (de) 2011-07-22 2014-03-05 Karel Paul Bouter Ernährungsprodukt, umfassend ein Biguanid
EP2742020B1 (de) 2011-08-08 2017-10-25 Immunomet Therapeutics Inc. N1-cyclische amin-n5-substituierte biguanidderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzung damit
KR101424667B1 (ko) * 2011-08-08 2014-08-04 한올바이오파마주식회사 Ｎ1-고리아민-ｎ2-치환된 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물
EP2742019B1 (de) * 2011-08-08 2021-03-03 Immunomet Therapeutics Inc. N1-cyclische-amin-n5-substituierte biguanidderivate und pharmazeutische zusammensetzung damit
US11465989B2 (en) 2014-04-17 2022-10-11 ImmunoMet Therapeutics, Inc. Guanidine compounds and use thereof
CN104262205B (zh) * 2014-09-02 2017-04-12 浙江工业大学 N‑芳基双胍氢碘酸盐类化合物及其制备方法和应用
KR102216701B1 (ko) 2014-11-20 2021-02-18 이뮤노메트테라퓨틱스 인코포레이티드 바이구아나이드 화합물 및 이의 용도
FR3035787B1 (fr) 2015-05-07 2018-08-24 L'oreal Procede de traitement des matieres keratiniques a partir de derives de c-glycosides amides, acides ou ester, et la composition cosmetique les contenant
FR3053892A1 (fr) 2016-07-12 2018-01-19 Urgo Recherche Innovation Et Developpement Pansement permettant la liberation controlee et prolongee de la metformine
CN106822075A (zh) * 2017-03-31 2017-06-13 浙江萧山医院 二甲双胍在促进伤口愈合中的应用
FR3068974B1 (fr) 2017-07-12 2019-08-02 Urgo Recherche Innovation Et Developpement Pansement permettant la liberation controlee et prolongee d'actif
FR3088542B1 (fr) 2018-11-21 2021-03-19 Waterdiam France Sas Composition cicatrisante comprenant une eau électrolysée
CN110179776B (zh) * 2019-05-31 2022-09-06 宁夏医科大学 二甲双胍的新用途与二甲双胍组合物及组合物的制备方法和应用
CN112494469A (zh) * 2020-07-30 2021-03-16 吴学雷 二甲双胍在制备预防和/或治疗瘢痕的药物中的应用

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB852584A (en) 1956-05-31 1960-10-26 Us Vitamin Corp Biguanide compositions
US2961377A (en) 1957-08-05 1960-11-22 Us Vitamin Pharm Corp Oral anti-diabetic compositions and methods
US3098008A (en) * 1960-10-05 1963-07-16 Us Vitamin Pharm Corp Method for treatment of dermatological disorders
US3174901A (en) 1963-01-31 1965-03-23 Jan Marcel Didier Aron Samuel Process for the oral treatment of diabetes
US3468898A (en) 1966-05-26 1969-09-23 Sterling Drug Inc Bridged bis-biguanides and bis-guanidines
US3996232A (en) * 1970-11-23 1976-12-07 William H. Rorer, Inc. 1,5-Disubstituted biguanides
GB1351025A (en) 1971-08-20 1974-04-24 Aron Md Samuel J Oxadiazol-5-yl biguanide derivatives method for their preparation and pharmaceutical compositions containing them
US3852353A (en) 1972-12-12 1974-12-03 C Heaphy Oral hypoglycemic aminophenylsulfonyl-hydrocarbylbiguanides
US3929999A (en) 1972-12-12 1975-12-30 Clifford John Heaphy Oral hypoglycemic method
US4211770A (en) * 1973-01-16 1980-07-08 The Upjohn Company Treatment of psoriasis intralesionally with N6 -2'-O-dibutyryl cyclic AMP
DE2401450A1 (de) * 1973-01-16 1974-07-18 John James Voorhees Pharmazeutische zusammensetzung zur linderung von hautproliferationserkrankungen
CH602612A5 (de) 1974-10-11 1978-07-31 Hoffmann La Roche
FR2320735A1 (fr) * 1975-08-12 1977-03-11 Dabis Georges Composition anti-cellulite
US4163800A (en) * 1977-08-17 1979-08-07 The Procter & Gamble Company Topical composition and treatment of skin lesions therewith
NZ207147A (en) 1983-02-28 1987-08-31 Johnson & Johnson Prod Inc Adhesive bandage containing medicinal substance: pad and base prepared from bulky, non-woven material
FR2552305B1 (fr) * 1983-09-22 1985-12-20 Salkin Andre Composition a pouvoir bactericide eleve contenant un biguanide et une pyrimidine
FR2585572B3 (fr) 1985-07-31 1987-12-31 Hugelin Andre Nouvelles compositions pharmaceutiques a base d'un sel de l'acide p. chlorophenoxyacetique destinees au traitement des neuropathies et assurant la regeneration nerveuse
FR2611500B1 (fr) * 1987-03-06 1990-05-04 Lipha Emploi de derives du biguanide dans la preparation de medicaments
AU1834188A (en) 1987-06-29 1989-01-05 Kendall Company, The Novel medicated dressings
US5246708A (en) 1987-10-28 1993-09-21 Pro-Neuron, Inc. Methods for promoting wound healing with deoxyribonucleosides
SU1560212A1 (ru) * 1988-11-10 1990-04-30 Киевский Медицинский Институт Им.Акад.А.А.Богомольца Способ лечени сифилиса
IT1241994B (it) 1990-08-30 1994-02-02 Idi Farmaceutici Composizione farmaceutica ad effetto cicatrizzante.
IL97771A (en) * 1991-04-04 1996-12-05 Sion Narrow Weaving Dry polymeric material having antimicrobial activity
IT1249711B (it) * 1991-09-30 1995-03-09 Boniscontro E Gazzone S R L Composizioni farmaceutiche, per uso topico, contenenti "scavengers" di radicali liberi dell'ossigeno e antibatterici,indicate nella terapia dei tessuti superficiali.
IT1256111B (it) * 1992-11-23 1995-11-28 Lifegroup Spa Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica
JP3493692B2 (ja) 1993-09-09 2004-02-03 三菱マテリアル株式会社 ビスビグアナイド系化合物およびそれを含む殺菌剤
DE19503336C2 (de) * 1995-02-02 1998-07-30 Lohmann Therapie Syst Lts Arzneiform zur Abgabe von Wirkstoffen an Wunden, Verfahren zu ihrer Herstellung und ihre Verwendung
US5747527A (en) * 1995-06-06 1998-05-05 Shaman Pharmaceuticals, Inc. Furanoeremophilane and eremophilanolide sesquiterpenes for treatment of diabetes
US5668084A (en) 1995-08-01 1997-09-16 Zeneca Inc. Polyhexamethylene biguanide and surfactant composition and method for preventing waterline residue
US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
US5827898A (en) * 1996-10-07 1998-10-27 Shaman Pharmaceuticals, Inc. Use of bisphenolic compounds to treat type II diabetes
US5837255A (en) * 1996-12-10 1998-11-17 Shaman Pharmaceuticals, Inc. Method of reducing blood glucose by administering Harunganin or Vismin
US5741926A (en) * 1997-02-12 1998-04-21 Shaman Pharmaceuticals, Inc. Aniline derivatives having antihyperglycemic activity
US5811078A (en) * 1997-03-14 1998-09-22 Adolor Corporation Spray formulations of antihyperalgesic opiates and method of treating topical hyperalgesic conditions therewith
JP3054758B2 (ja) * 1997-03-27 2000-06-19 小林製薬株式会社 外傷用組成物
CN1197643A (zh) * 1997-04-30 1998-11-04 谢瑞钢 一种创伤油膏
EP1039890B1 (de) * 1997-12-08 2004-03-17 Bristol-Myers Squibb Company Neue metformin salze und verfahren
NZ505192A (en) * 1997-12-22 2003-05-30 Euro Celtique S A method of preventing abuse of opioid dosage forms , whereby opioid agonist and opioid antagonist are only extractable together
CN1205922C (zh) * 1998-07-24 2005-06-15 柳署弘 制备含有胆汁酸的澄清水溶液剂型
EP1135116A1 (de) 1998-12-05 2001-09-26 Fresenius Kabi Deutschland GmbH Verwendung von poly (hexamethylen) biguanid zur herstellung eines mittels zur förderung der heilung von infektionsfreien wunden
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
CO5200844A1 (es) * 1999-09-17 2002-09-27 Novartis Ag Una combinacion que comprende nateglinida y cuando por menos otro compuesto antidiabetico usada para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con dibetes
PH12000002657B1 (en) * 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
US6515117B2 (en) * 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
AU3982601A (en) * 2000-02-23 2001-09-03 Orentreich Foundation For The Methods and compositions for the treatment of alopecia and other disorders of the pilosebaceous apparatus
ATE266409T1 (de) * 2000-04-13 2004-05-15 Pfizer Prod Inc Synergistische wirkung von glyburide und milrinone

Also Published As

Publication number Publication date
ATE300942T1 (de) 2005-08-15
UA76415C2 (uk) 2006-08-15
BRPI0111142B8 (pt) 2018-05-02
AR032617A1 (es) 2003-11-19
BR0111142A (pt) 2003-04-08
KR20030029050A (ko) 2003-04-11
US20030187036A1 (en) 2003-10-02
DK1283708T3 (da) 2005-12-27
MXPA02011622A (es) 2003-03-27
BRPI0111142B1 (pt) 2017-10-24
JP4987209B2 (ja) 2012-07-25
CA2410025A1 (fr) 2001-12-06
ES2244625T3 (es) 2005-12-16
EE200200657A (et) 2004-06-15
CN100420439C (zh) 2008-09-24
DE60112431T2 (de) 2006-06-01
WO2001091696A8 (fr) 2003-01-09
JP2003534359A (ja) 2003-11-18
HUP0302038A2 (hu) 2003-09-29
NO20025635D0 (no) 2002-11-22
PT1283708E (pt) 2005-11-30
SK287249B6 (sk) 2010-04-07
HUP0302038A3 (en) 2009-08-28
BRPI0111142C1 (pt) 2021-05-25
EP1283708B1 (de) 2005-08-03
WO2001091696A3 (fr) 2002-06-06
MY137468A (en) 2009-01-30
AU2001264011B2 (en) 2005-09-15
EP1283708A2 (de) 2003-02-19
BG65847B1 (bg) 2010-03-31
FR2809310A1 (fr) 2001-11-30
CA2410025C (fr) 2011-09-06
HU229205B1 (en) 2013-09-30
BG107304A (bg) 2003-06-30
WO2001091696A2 (fr) 2001-12-06
EE05393B1 (et) 2011-04-15
NO20025635L (no) 2003-01-21
FR2809310B1 (fr) 2004-02-13
SK16582002A3 (sk) 2003-04-01
AU6401101A (en) 2001-12-11
US7199159B2 (en) 2007-04-03
PL359063A1 (en) 2004-08-23
ECSP024359A (es) 2004-03-23
CN1635880A (zh) 2005-07-06

Similar Documents

Publication Publication Date Title
DE60112431D1 (de) Verwendung von biguanidederivaten zur herstellung eines vernarbungsfördernden medikaments
ATE248599T1 (de) Verwendung von xenon zur herstellung einer pharmazeutischen zusammensetzung zur behandlung von neurovergiftungen
DE59806139D1 (de) Verwendung von Pyrimidinderivaten zur Herstellung eines Arzneimittels zur Prävention von Krebs
DE60224111D1 (de) Bausatz zur Herstellung einer Verabreichungsform zur Abgabe einer bioaktiven Substanz
DE60021099D1 (de) Transdermale, in form einer haftschicht ausgebildete zweifachmedikamenten-verabreichungsvorrichtung
DE60037395D1 (de) Herstellung eines halbleiter-bauelementes
DE60118859D1 (de) Pharmazeutische Zusammensetzung enthaltend Trehalose zur ophthalmischen Verwendung
DE60227718D1 (de) Verwendung von 2-Fuoro-3-Ketoestern zur Herstellung von 3-Fuoro-6,7,8,9-tetrahydro-4H-pyrimidoÄ1,2-aÜpyrimidin-4-onen
DE60019960D1 (de) Herstellung von isobutencopolymere
DE60325551D1 (de) Verwendung eines gsk-3beta-hemmers bei der herstellung eines arzneimittel zur erhöhung der knochenbildung
DE69910202D1 (de) EGR-1 zur Herstellung eines Medikamentes zur Behandlung von Wunden
DE60018173D1 (de) Giessform zur herstellung eines kühlelementes
DE60318327D1 (de) Verwendung von resveratrol zur herstellung eines arzneimittels zur behandlung von grippe
DE60142051D1 (de) Herstellung von perfluorolefinen
DE60233589D1 (de) Verfahren zur herstellung von echinocandinderivaten
DE50209948D1 (de) Verwendung von Scopinester Derivaten zur Herstellung von Arzneimitteln
DE60108668D1 (de) Verfahren zur herstellung von phenethylamin-derivaten
ATE314850T1 (de) Verwendung einer pharmazeutische zusammensetzung enthaltend desoxypeganin zur behandlung der nikotinabhängigkeit
DE60230629D1 (de) Verwendung von 2,5-dihydroxybenzolsulfonsäure-derivaten bei der herstellung eines medikaments zur verstärkung der wirkung anderer arzneimittel zur behandlung der erektilen dysfunktion
AR026073A1 (es) Composicion farmaceutica acuosa que contiene ciclesonida
DE60128640D1 (de) Verfahren zur Herstellung von optisch aktivem 4-Halo-3-Hydroxybutanoat
DE60033207D1 (de) Werkzeug zur herstellung von nockenwellen durch einwalzen
DE60101124D1 (de) Verfahren zur Herstellung von Sulfinaten
DE60016608D1 (de) Herstellung von sulfonylimin-verbindungen
DE60141761D1 (de) Verfahren zur herstellung von thiazolderivaten mit pestizider wirkung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition