DE60032082D1 - Vorrichtung zur transdermalen Verabreichung von einer Substanz - Google Patents

Vorrichtung zur transdermalen Verabreichung von einer Substanz

Info

Publication number
DE60032082D1
DE60032082D1 DE60032082T DE60032082T DE60032082D1 DE 60032082 D1 DE60032082 D1 DE 60032082D1 DE 60032082 T DE60032082 T DE 60032082T DE 60032082 T DE60032082 T DE 60032082T DE 60032082 D1 DE60032082 D1 DE 60032082D1
Authority
DE
Germany
Prior art keywords
housing
pharmaceutical agent
microneedles
substance
microns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60032082T
Other languages
English (en)
Other versions
DE60032082T2 (de
Inventor
Zeil B Rosenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE60032082D1 publication Critical patent/DE60032082D1/de
Application granted granted Critical
Publication of DE60032082T2 publication Critical patent/DE60032082T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Surgical Instruments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60032082T 1999-09-22 2000-08-07 Vorrichtung zur transdermalen Verabreichung von einer Substanz Expired - Lifetime DE60032082T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/401,452 US6623457B1 (en) 1999-09-22 1999-09-22 Method and apparatus for the transdermal administration of a substance
US401452 1999-09-22

Publications (2)

Publication Number Publication Date
DE60032082D1 true DE60032082D1 (de) 2007-01-11
DE60032082T2 DE60032082T2 (de) 2007-06-21

Family

ID=23587826

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60032082T Expired - Lifetime DE60032082T2 (de) 1999-09-22 2000-08-07 Vorrichtung zur transdermalen Verabreichung von einer Substanz

Country Status (9)

Country Link
US (4) US6623457B1 (de)
EP (1) EP1086718B1 (de)
JP (1) JP2001149485A (de)
AT (1) ATE346644T1 (de)
AU (1) AU778234B2 (de)
CA (1) CA2315469C (de)
DE (1) DE60032082T2 (de)
ES (1) ES2273639T3 (de)
SG (1) SG92728A1 (de)

Families Citing this family (301)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6331266B1 (en) * 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
US20020156453A1 (en) * 1999-10-14 2002-10-24 Pettis Ronald J. Method and device for reducing therapeutic dosage
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
US6494865B1 (en) * 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
US8465468B1 (en) * 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
EP1416980A2 (de) * 1999-12-30 2004-05-12 Redeon, Inc. Stapelbare mikronadel-systeme
US6595947B1 (en) * 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
AU2001275138A1 (en) * 2000-06-02 2001-12-17 The University Of Utah Research Foundation Active needle devices with integrated functionality
US20040175360A1 (en) * 2000-06-29 2004-09-09 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
WO2002028471A1 (de) 2000-10-05 2002-04-11 Thomas Marsoner Medizinische injektionseinrichtung
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
AU2002237703A1 (en) * 2000-11-09 2002-06-18 Biovalve Technologies, Inc. Microneedle adapter
EP1345646A2 (de) * 2000-12-14 2003-09-24 Georgia Tech Research Corporation Mikronadel-vorrichtungen und deren herstellung
US7850663B2 (en) 2001-01-12 2010-12-14 Becton, Dickinson And Company Medicament microdevice delivery system, cartridge and method of use
US20040071734A1 (en) * 2001-02-23 2004-04-15 Nathalie Garcon Novel vaccine
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
EP1381423A1 (de) * 2001-04-13 2004-01-21 Becton, Dickinson and Company Verfahren und vorrichtung zur intradermale abgabe von substanzen für systemischer absorption
DE60233939D1 (de) * 2001-04-20 2009-11-19 Alza Corp Mikroprojektionsanordnung mit einem überzug, der ein vorteilhaftes mittel enthält
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
AU2007203302B2 (en) * 2001-04-20 2010-07-01 Alza Corporation Microprojection array immunization patch and method
DE10293048T1 (de) * 2001-04-27 2003-07-31 Glaxosmithkline Biolog Sa Neuer Impfstoff
US20060018877A1 (en) * 2001-06-29 2006-01-26 Mikszta John A Intradermal delivery of vacccines and therapeutic agents
CN1253220C (zh) * 2001-06-29 2006-04-26 贝克顿迪肯森公司 通过微管在真皮内输入疫苗和基因治疗剂
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
PT1465535E (pt) * 2001-12-20 2008-02-08 Alza Corp Microprojecções que perfuram a pele tendo controlo de profundidade de perfuração
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7047070B2 (en) * 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
JP4764626B2 (ja) 2002-05-06 2011-09-07 ベクトン・ディキンソン・アンド・カンパニー 薬剤の薬物動力学を制御する方法およびデバイス
US20060264886A9 (en) * 2002-05-06 2006-11-23 Pettis Ronald J Method for altering insulin pharmacokinetics
MXPA05000597A (es) 2002-07-19 2005-04-28 3M Innovative Properties Co Dispositivos de microaguja y aparatos de administracion por microaguja.
US20040082934A1 (en) * 2002-08-30 2004-04-29 Pettis Ronald J. Method of controlling pharmacokinetics of immunomodulatory compounds
US20040051019A1 (en) 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
EP1590034B1 (de) * 2002-10-07 2014-05-14 Biovalve Technologies, Inc. Pflaster mit mikronadelanordnung
DK200201823A (da) 2002-11-26 2004-05-27 Maersk Medical As Forbindelsesstykke for en slangeforbindelse
KR20060009303A (ko) * 2003-05-06 2006-01-31 벡톤 디킨슨 앤드 컴퍼니 인슐린 약동학을 변경하는 방법
JP4842807B2 (ja) * 2003-06-02 2011-12-21 ベクトン・ディキンソン・アンド・カンパニー カートリッジ付きの医薬マイクロデバイス給送システム
AU2004244909A1 (en) * 2003-06-10 2004-12-16 Medrx Co., Ltd. Process for producing pad base for transdermal drug administration, pad base for transdermal drug administration and needle
JP2005021678A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベースの製造方法及び経皮投薬用パッドベース、並びに注射針
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
JP5456234B2 (ja) * 2003-06-30 2014-03-26 アルザ・コーポレーシヨン 非揮発性の対イオンを含有する被覆された微小突起のための製剤
EP1648363B1 (de) 2003-07-03 2019-03-06 Corium International, Inc. Wundverband, vorrichtung zur inhaltsstoffzuführung und iv-hold-down sowie verfahren im zusammenhang damit
US7766902B2 (en) 2003-08-13 2010-08-03 Wisconsin Alumni Research Foundation Microfluidic device for drug delivery
US8353861B2 (en) * 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
EP1680057A4 (de) * 2003-10-24 2007-10-31 Alza Corp Gerät und verfahren zur verbesserung der transdermalen arzneimittelabgabe
WO2005065765A1 (en) * 2003-12-29 2005-07-21 3M Innovative Properties Company Medical devices and kits including same
CA2560840C (en) * 2004-03-24 2014-05-06 Corium International, Inc. Transdermal delivery device
KR101158939B1 (ko) 2004-03-26 2012-06-21 우노메디컬 에이/에스 주사세트를 위한 주사장치
US20050251095A1 (en) * 2004-05-07 2005-11-10 Giap Brandon C Improved medication injection device
BRPI0509788A (pt) 2004-05-13 2007-10-23 Alza Corp aparato e método para liberação transdérmica de agentes de hormÈnio paratireóides
ES2650188T3 (es) * 2004-06-10 2018-01-17 3M Innovative Properties Company Dispositivo y kit de aplicación de parches
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
ATE490037T1 (de) 2004-08-16 2010-12-15 Functional Microstructures Ltd Verfahren zur herstellung einer mikronadel oder eines mikroimplantats
AR050608A1 (es) * 2004-08-19 2006-11-08 Alza Corp Aparato y metodo para administracion transdermica de factores de crecimiento endotelial vascular
US7316665B2 (en) * 2004-08-25 2008-01-08 Becton, Dickinson And Company Method and device for the delivery of a substance including a covering
US8267889B2 (en) 2004-11-18 2012-09-18 3M Innovative Properties Company Low-profile microneedle array applicator
CA2587387C (en) 2004-11-18 2013-06-25 3M Innovative Properties Company Method of contact coating a microneedle array
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
US9174035B2 (en) 2004-11-18 2015-11-03 3M Innovative Properties Company Microneedle array applicator and retainer
US7846488B2 (en) * 2004-11-18 2010-12-07 3M Innovative Properties Company Masking method for coating a microneedle array
JP5039559B2 (ja) * 2004-11-26 2012-10-03 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 微細構造製造方法および微細構造製造装置
KR20070086306A (ko) 2004-12-10 2007-08-27 우노메디컬 에이/에스 주입기
WO2006064271A1 (en) * 2004-12-17 2006-06-22 Functional Microstructures Limited Microneedle device for transdermal transport of fluid
EP1848492A1 (de) * 2005-02-16 2007-10-31 Alza Corporation Mikroprojektionsanordnungen mit erhöhter bioverträglichkeit
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
ATE555824T1 (de) 2005-04-11 2012-05-15 Infotonics Technology Ct Inc Blutüberwachungssysteme und verfahren dafür
WO2006115502A1 (en) * 2005-04-25 2006-11-02 Giap, Brandon, C. Improved medication injection device
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
EP1904158B1 (de) 2005-06-24 2013-07-24 3M Innovative Properties Company Faltbares Pflaster mit Mikronadelnanordnung
WO2007002521A2 (en) * 2005-06-27 2007-01-04 3M Innovative Properties Company Microneedle array applicator device
CA2613114C (en) * 2005-06-27 2015-02-24 3M Innovative Properties Company Microneedle cartridge assembly and method of applying
US20080214952A1 (en) * 2005-07-11 2008-09-04 Jose Mir Replaceable Cartridge for Allergy Testing System
EP1928537B1 (de) * 2005-09-02 2015-01-21 Intercell USA, Inc. Vorrichtungen für die transkutane Abgabe von Vakzine und transdermale Abgabe von Arzneimittel
US9358033B2 (en) * 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
EP1762259B1 (de) 2005-09-12 2010-09-08 Unomedical A/S Einfürungssystem für ein Infusionsset mit einem ersten und zweiten Federeinheit
GB0520757D0 (en) * 2005-10-12 2005-11-23 Vuppalapati Gunasekar Delivery device
US20070087029A1 (en) * 2005-10-14 2007-04-19 Pakala Syamasundar V Localized delivery to the lymphatic system
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
EP1957132A4 (de) * 2005-12-08 2010-04-21 Nanopass Technologies Ltd Mikronadel-adapter für vorrichtungen zur dosierten arzneiabgabe
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
AU2006329075A1 (en) 2005-12-23 2007-06-28 Unomedical A/S Injection device
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US9610459B2 (en) 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
JP5038334B2 (ja) 2006-02-28 2012-10-03 ウノメディカル アクティーゼルスカブ 注入部品のための挿入具及び針保護具を備えた注入部品
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US8343116B2 (en) 2008-01-04 2013-01-01 Edge Systems Corporation Apparatus and method for treating the skin
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20070265570A1 (en) * 2006-04-27 2007-11-15 Gerut Zachary E Device and method for treating skin prior to performing surgery
US20070276318A1 (en) * 2006-05-26 2007-11-29 Mit, Llp Iontosonic-microneedle applicator apparatus and methods
US20070276330A1 (en) * 2006-05-28 2007-11-29 Beck Patricia A Microneedles and methods of fabricating thereof
US20070276425A1 (en) * 2006-05-29 2007-11-29 Stanley Kim Painless Blood Sampling Lancet with Bundled Multiple Thin Needles
US20070282246A1 (en) * 2006-06-05 2007-12-06 Mit, Llp Iontosonic-microneedle biosensor apparatus and methods
KR20090026760A (ko) 2006-06-07 2009-03-13 우노메디컬 에이/에스 주입기
BRPI0712361A2 (pt) 2006-06-09 2012-06-19 Unomedical As suporte de montagem
US8012566B2 (en) * 2006-07-12 2011-09-06 Hewlett-Packard Development Company, L.P. Microneedles formed by electroplating and selectively releasing temperature sensitive layers
US20080015516A1 (en) * 2006-07-12 2008-01-17 Nanopass Technologies Ltd. Microneedle Devices With Controlled Uncapping
US8250729B2 (en) * 2006-07-12 2012-08-28 University Of Utah Research Foundation 3D fabrication of needle tip geometry and knife blade
KR100886633B1 (ko) * 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
JP2008029710A (ja) * 2006-07-31 2008-02-14 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai マイクロニードル型パッチ及びその製造方法
CN101500627B (zh) 2006-08-02 2012-03-14 优诺医疗有限公司 套管和输送装置
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
WO2008042902A2 (en) 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
EP1917990A1 (de) 2006-10-31 2008-05-07 Unomedical A/S Infusionsset
US20080114340A1 (en) * 2006-11-01 2008-05-15 Biotex, Inc. System and method for reducing photon scatter in dermal tissue
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
US8523926B2 (en) * 2007-01-19 2013-09-03 Joseph Neev Devices and methods for generation of subsurface microdisruptions for biomedical applications
US10588694B1 (en) 2007-01-19 2020-03-17 Joseph Neev Devices and methods for generation of subsurface micro-disruptions for biomedical applications
EP2121111B1 (de) 2007-01-22 2018-03-14 Corium International, Inc. Applikator für mikronadelanordnung
ES2820335T3 (es) 2007-04-16 2021-04-20 Corium Inc Matrices de microagujas coladas con disolvente que contienen agente activo
WO2008152052A1 (en) * 2007-06-14 2008-12-18 Berna Biotech Ag Intradermal influenza vaccine
CA2691369A1 (en) 2007-06-20 2008-12-24 Unomedical A/S A catheter and a method and an apparatus for making such catheter
CA2691341A1 (en) 2007-07-03 2009-01-08 Unomedical A/S Inserter having bistable equilibrium states
US20090041810A1 (en) * 2007-07-09 2009-02-12 Andrianov Alexander K Immunostimulating polyphosphazene compounds for intradermal immunization
PT2173410E (pt) 2007-07-10 2011-05-05 Unomedical As Reservat?rio de armazenamento de energia bit?rmica
KR20100049576A (ko) 2007-07-18 2010-05-12 우노메디컬 에이/에스 피벗동작을 갖는 삽입장치
ES2422031T3 (es) * 2007-07-21 2013-09-06 Stanley Kim Sistema de lanceta
US8328720B2 (en) 2007-08-10 2012-12-11 Infotonics Technology Center, Inc. MEMS interstitial prothrombin time test
JP5223278B2 (ja) * 2007-09-27 2013-06-26 凸版印刷株式会社 マイクロニードル製造方法
EP2205169B1 (de) * 2007-09-28 2016-11-16 The Queen's University of Belfast Abgabevorrichtung und- verfahren
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2009097451A1 (en) 2008-01-29 2009-08-06 Edge Systems Corporation Apparatus and method for treating the skin
NZ587111A (en) 2008-02-13 2012-03-30 Unomedical As Infusion part including seal between cannula and fluid inlet or outlet
MX2010009087A (es) 2008-02-20 2011-05-03 Unomedical As Dispositivo de insercion con parte horizontalmente movil.
US9408971B2 (en) * 2008-03-31 2016-08-09 Covidien Lp Self-capping syringe assembly with one-way valve
WO2009130926A1 (ja) * 2008-04-22 2009-10-29 南部化成株式会社 経皮投薬方法、ニードル形成体及び経皮投薬装置
US10543123B2 (en) 2008-04-28 2020-01-28 Joseph Neev Devices and methods for generation of subsurface micro-disruptions for opthalmic surgery and opthalmic applications
JP5476062B2 (ja) * 2008-07-25 2014-04-23 南部化成株式会社 経皮投薬デバイス
US8795259B2 (en) 2008-08-01 2014-08-05 Wisconsin Alumni Research Foundation Drug delivery platform incorporating hydrogel pumping mechanism with guided fluid flow
US8986250B2 (en) 2008-08-01 2015-03-24 Wisconsin Alumni Research Foundation Drug delivery platform utilizing hydrogel pumping mechanism
US8545856B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US8551505B2 (en) 2008-10-31 2013-10-08 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9050317B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8788211B2 (en) 2008-10-31 2014-07-22 The Invention Science Fund I, Llc Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition
US8545855B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9060931B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US9072688B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8603495B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US8603494B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8721583B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8563012B2 (en) 2008-10-31 2013-10-22 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8731840B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8762067B2 (en) 2008-10-31 2014-06-24 The Invention Science Fund I, Llc Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data
US8793075B2 (en) 2008-10-31 2014-07-29 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8603496B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US9040087B2 (en) 2008-10-31 2015-05-26 The Invention Science Fund I, Llc Frozen compositions and methods for piercing a substrate
US9072799B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9060934B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8731841B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US20100111857A1 (en) 2008-10-31 2010-05-06 Boyden Edward S Compositions and methods for surface abrasion with frozen particles
US9060926B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9050070B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8409376B2 (en) 2008-10-31 2013-04-02 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8518031B2 (en) 2008-10-31 2013-08-27 The Invention Science Fund I, Llc Systems, devices and methods for making or administering frozen particles
US8725420B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
AU2009315210B2 (en) 2008-11-17 2012-10-11 Yoichi Inaba Simple device for treating trichophytosis unguium
JP2012509106A (ja) * 2008-11-18 2012-04-19 スリーエム イノベイティブ プロパティズ カンパニー 中空のマイクロニードルアレイ及び方法
RU2011130565A (ru) 2008-12-22 2013-01-27 Уномедикал А/С Медицинское устройство, содержащее клеящую прокладку
FI20095433A0 (fi) * 2009-04-20 2009-04-20 Valtion Teknillinen Mikroneula
WO2011006009A1 (en) 2009-07-08 2011-01-13 Edge Systems Corporation Devices, systems and methods for treating the skin using time-release substances
BR112012002050A2 (pt) 2009-07-30 2016-05-17 Unomedical As dispositivo insersor com parte de movimento horizontal.
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
AU2010280713A1 (en) 2009-08-07 2012-02-02 Unomedical A/S Delivery device with sensor and one or more cannulas
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
EP2477559A4 (de) 2009-09-17 2015-05-27 Zipline Medical Inc Schnellschliessende chirurgische verschlussvorrichtung
US10159825B2 (en) 2009-09-17 2018-12-25 Zipline Medical, Inc. Rapid closing surgical closure device
JP2013508119A (ja) 2009-10-26 2013-03-07 エムキネティクス， インコーポレイテッド 神経、筋肉および身体組織の電磁刺激のための方法および装置
DE102009046581A1 (de) * 2009-11-10 2011-05-12 Robert Bosch Gmbh Herstellungsverfahren für eine poröse Mikronadelanordnung und entsprechende poröse Mikronadelanordnung und entsprechender Substratverbund
JP5785559B2 (ja) 2009-12-16 2015-09-30 クロンテック ファーマ アーベー 注射針および注射装置
CA2689400C (en) * 2009-12-30 2023-01-10 Kenneth W. Adams Therapeutic agent delivery apparatus and process
US8328757B2 (en) * 2010-01-08 2012-12-11 Wisconsin Alumni Research Foundation Bladder arrangement for microneedle-based drug delivery device
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
US9327105B2 (en) 2010-03-26 2016-05-03 Itrace Biomedical Inc. Active transdermal drug delivery system and the method thereof
MX2012011085A (es) 2010-03-30 2012-10-10 Unomedical As Dispositivo medico.
US8439945B2 (en) 2010-05-03 2013-05-14 Zipline Medical, Inc. Methods for biopsying tissue
EP2566501B1 (de) 2010-05-04 2019-03-13 Corium International, Inc. Verfahren und vorrichtung zur transdermalen verabreichung von parathormon mithilfe eines mikroprojektions-arrays
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
AU2011267977B2 (en) 2010-06-14 2015-02-05 Zipline Medical, Inc. Methods and apparatus for inhibiting scar formation
EP3578205A1 (de) 2010-08-06 2019-12-11 ModernaTX, Inc. Pharmazeutische zusammensetzungen enthaltenbearbeitete nukleinsäuren und ihre medizinische verwendung
EP2433663A1 (de) 2010-09-27 2012-03-28 Unomedical A/S Einführsystem
HUE058896T2 (hu) 2010-10-01 2022-09-28 Modernatx Inc N1-metil-pszeudo-uracilt tartalmazó ribonukleinsavak és azok felhasználásai
EP2436412A1 (de) 2010-10-04 2012-04-04 Unomedical A/S Sprinklerkanüle
WO2012057270A1 (ja) * 2010-10-27 2012-05-03 Ａｓｔｉ株式会社 マイクロニードルアレイ装着用治具とマイクロニードルアレイ装置
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US20120135526A1 (en) * 2010-11-23 2012-05-31 Kenneth Greenberg Low-pressure biolistic barrels
US10244981B2 (en) 2011-03-30 2019-04-02 SensiVida Medical Technologies, Inc. Skin test image analysis apparatuses and methods thereof
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US8636696B2 (en) 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
US9457183B2 (en) 2011-06-15 2016-10-04 Tripep Ab Injection needle and device
WO2013009690A2 (en) 2011-07-09 2013-01-17 The Regents Of The University Of California Leukemia stem cell targeting ligands and methods of use
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
US9700245B2 (en) 2011-09-23 2017-07-11 Itrace Biomedical Inc. Transdermal analyte extraction and detection system and the method thereof
RU2648950C2 (ru) 2011-10-03 2018-04-02 Модерна Терапьютикс, Инк. Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение
CN103957962B (zh) 2011-10-05 2017-07-07 犹诺医药有限公司 用于同时***多个经皮部分的***物
EP2578190A1 (de) * 2011-10-07 2013-04-10 Sanofi-Aventis Deutschland GmbH Intraokulare Injektionsvorrichtung
EP2583715A1 (de) 2011-10-19 2013-04-24 Unomedical A/S Infusionsschlauchsystem und Herstellungsverfahren
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US10123801B2 (en) 2011-11-01 2018-11-13 Zipline Medical, Inc. Means to prevent wound dressings from adhering to closure device
US9050086B2 (en) 2011-11-01 2015-06-09 Zipline Medical, Inc. Surgical incision and closure apparatus
US10123800B2 (en) 2011-11-01 2018-11-13 Zipline Medical, Inc. Surgical incision and closure apparatus with integrated force distribution
US8323313B1 (en) 2011-11-01 2012-12-04 Zipline Medical, Inc. Surgical incision and closure apparatus with integrated force distribution
US9561034B2 (en) 2011-11-01 2017-02-07 Zipline Medical, Inc. Surgical incision and closure apparatus
EP2791160B1 (de) 2011-12-16 2022-03-02 ModernaTX, Inc. Modifizierte mrna zusammensetzungen
US10383835B2 (en) 2012-03-14 2019-08-20 The Regents Of The University Of California Treatment of inflammatory disorders in non-human mammals
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
AU2013243951A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of secreted proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
EP2817027A4 (de) * 2012-04-03 2015-12-16 Theraject Inc Lösliche mikronadelfelder zur bukkalen verabreichung von impfstoffen
WO2013171907A1 (ja) * 2012-05-18 2013-11-21 大勝 明 注射針、および、キット製剤
KR200466758Y1 (ko) 2012-06-01 2013-05-07 인싸이토(주) 경피내 주사기 모듈
JP5903016B2 (ja) 2012-06-27 2016-04-13 コスメディ製薬株式会社 マイクロニードルパッチの保護離型シート
JP6418544B2 (ja) * 2012-06-27 2018-11-07 コスメディ製薬株式会社 マイクロニードルパッチの保護離型シート
WO2014064534A2 (en) 2012-10-05 2014-05-01 Chrontech Pharma Ab Injection needle, device, immunogenic compositions and method of use
EP2922554B1 (de) 2012-11-26 2022-02-23 ModernaTX, Inc. Terminal modifizierte rns
MX2015008157A (es) 2012-12-21 2016-02-22 Corium Int Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
US10179239B2 (en) 2013-01-15 2019-01-15 Itrace Biomedical Inc. Personalized pain management treatments
US9710607B2 (en) 2013-01-15 2017-07-18 Itrace Biomedical Inc. Portable electronic therapy device and the method thereof
US9717893B2 (en) 2013-02-13 2017-08-01 Hisamitsu Pharmaceutical Co., Ltd. Microneedle array
US10183156B2 (en) 2013-02-28 2019-01-22 Sorrento Therapeutics, Inc. Transdermal drug delivery device
WO2014132239A1 (en) 2013-02-28 2014-09-04 Kimberly-Clark Worldwide, Inc. Drug delivery device
CN105142711B (zh) 2013-03-12 2019-01-22 考里安国际公司 微突起施加器
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
ES2761580T3 (es) 2013-03-15 2020-05-20 Corium Inc Micromatrices para suministro de agente terapéutico, métodos de uso y métodos de fabricación
ES2908339T3 (es) 2013-03-15 2022-04-28 Corium Inc Micromatriz para el suministro de un agente terapéutico y métodos de uso
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
EP4194028A1 (de) 2013-03-15 2023-06-14 Corium Pharma Solutions, Inc. Mehrfachaufprall-mikroprojektionsapplikatoren
EP2967633B1 (de) 2013-03-15 2018-04-25 Edge Systems LLC Vorrichtungen zur hautbehandlung
EP3041504B1 (de) 2013-09-03 2021-08-25 Georgia Tech Research Corporation Wärmestabile impfstoffformulierungen und mikronadeln
EA201690675A1 (ru) 2013-10-03 2016-08-31 Модерна Терапьютикс, Инк. Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности
CN105873525A (zh) 2014-01-05 2016-08-17 奇普林医药公司 仪表化伤口闭合装置
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
KR20160144980A (ko) * 2014-04-14 2016-12-19 도판 인사츠 가부시키가이샤 주입 기구
WO2015168210A1 (en) 2014-04-30 2015-11-05 Kimberly-Clark Worldwide, Inc. Transdermal drug delivery apparatus and methods
RU2667305C2 (ru) 2014-04-30 2018-09-18 Кимберли-Кларк Ворлдвайд, Инк. Часть в виде контейнера для устройств и способов трансдермальной доставки лекарств
EP3137151B1 (de) 2014-04-30 2019-08-28 Sorrento Therapeutics, Inc. Steuergeräteabschnitt einer vorrichtung zur transdermalen arzneimittelabgabe
KR101724655B1 (ko) * 2014-06-02 2017-04-13 주식회사 아모라이프사이언스 마이크로 니들 패치 및 그의 제조 방법
US9987427B1 (en) * 2014-06-24 2018-06-05 National Technology & Engineering Solutions Of Sandia, Llc Diagnostic/drug delivery “sense-respond” devices, systems, and uses thereof
US9907941B2 (en) 2014-07-21 2018-03-06 The Cleveland Clinic Foundation Convection enhanced delivery device and system
US9968765B2 (en) 2014-07-21 2018-05-15 The Cleveland Clinic Foundation Convection enhanced delivery device and system
KR101636775B1 (ko) * 2014-08-19 2016-07-08 아주대학교산학협력단 부위마취 장치 및 방법
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
JP5931155B2 (ja) * 2014-09-30 2016-06-08 日本写真印刷株式会社 マイクロニードルシートの梱包体及びその製造方法
JP6906885B2 (ja) 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
EP4324414A3 (de) 2014-12-23 2024-05-01 HydraFacial LLC Vorrichtungen und verfahren zur hautbehandlung mit einem rollball oder einem dochtelement
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
CN104922791B (zh) * 2015-05-26 2018-10-26 上海交通大学 无创针灸贴片及其制备方法
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2018527052A (ja) 2015-07-08 2018-09-20 エッジ システムズ エルエルシー 育毛を促進するための装置、システムおよび方法
KR102543162B1 (ko) 2016-03-01 2023-06-15 키토테크 메디컬 인코포레이티드 상처 봉합을 위한 마이크로 구조-기반 시스템, 장치, 및 방법
WO2018081795A1 (en) 2016-10-31 2018-05-03 Zipline Medical, Inc. Systems and methods for monitoring physical therapy of the knee and other joints
US11241563B2 (en) * 2016-12-22 2022-02-08 Johnson & Johnson Consumer Inc. Microneedle arrays and methods for making and using
WO2018119090A1 (en) * 2016-12-22 2018-06-28 Ohio State Innovation Foundation Interpentrating microstructures for nanochannel-based cargo delivery
EP3582752A1 (de) 2017-02-17 2019-12-25 Allergan, Inc. Mikronadelanordnung mit wirkstoff
WO2019033362A1 (zh) * 2017-08-17 2019-02-21 深圳华迈兴微医疗科技有限公司 一种采血装置及其控制设备
CN109394236B (zh) * 2017-08-17 2022-04-01 李泉 一种采血装置及其控制设备
JPWO2019059265A1 (ja) * 2017-09-20 2019-12-19 シンクランド株式会社 マイクロニードルシート及びマイクロニードルシートの製造方法
TWI666036B (zh) * 2017-10-27 2019-07-21 研能科技股份有限公司 穿戴式人體胰島素注入供液裝置
TWI657842B (zh) * 2017-10-27 2019-05-01 研能科技股份有限公司 人體胰島素注入之供液裝置
CN112312892A (zh) 2018-06-29 2021-02-02 强生消费者公司 用于递送活性物质的三维微流体装置
GB2574074B (en) 2018-07-27 2020-05-20 Mclaren Applied Tech Ltd Time synchronisation
GB2588236B (en) 2019-10-18 2024-03-20 Mclaren Applied Ltd Gyroscope bias estimation
BR112022007740A2 (pt) * 2019-10-24 2022-07-12 Hopkins Janine Dispositivo aplicador e métodos de uso
WO2021168345A1 (en) 2020-02-19 2021-08-26 Kitotech Medical, Inc. Microstructure systems and methods for pain treatment
US20230134699A1 (en) * 2020-04-09 2023-05-04 Carnegie Mellon University Hybrid microneedle arrays
CN112869871B (zh) * 2021-01-11 2022-10-14 杭州维纳安可医疗科技有限责任公司 消融装置及其控制方法、装置、***、存储介质
WO2022159736A1 (en) * 2021-01-22 2022-07-28 Sorrento Therapeutics, Inc. Device for microliter-scale lymphatic delivery of coronavirus vaccines
US20220330860A1 (en) 2021-04-14 2022-10-20 Neoenta LLC Dermal patch system
KR102577073B1 (ko) * 2021-04-27 2023-09-11 주식회사 이엘홀딩스 마이크로 니들을 이용한 문신 패치
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample
US11957346B2 (en) 2022-02-18 2024-04-16 Kitotech Medical, Inc. Force modulating deep skin staples and instruments
WO2023193010A1 (en) 2022-04-01 2023-10-05 The Regents Of The University Of California Methods of improving cancer immunotherapy
US20230346666A1 (en) 2022-04-29 2023-11-02 Colgate-Palmolive Company Personal Care Composition

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1699012A (en) * 1927-11-22 1929-01-15 Joseph S Naylor Stock and poultry marker
US3072122A (en) * 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
FR1584474A (de) 1968-02-20 1969-12-26
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
DE2513467C3 (de) * 1975-03-26 1979-10-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Gerät zur Infusion von Flüssigkeiten in den menschlichen oder tierischen Körper
IT1202218B (it) * 1985-05-21 1989-02-02 Mario Aluigi Piastre di derivazione multi-aghi per uso mesoterapico e relative custodie salva punte
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5312456A (en) 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
ATE211398T1 (de) * 1994-02-28 2002-01-15 Novo Nordisk As Nadeleinheit
AU5869796A (en) * 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
ATE234129T1 (de) 1996-06-18 2003-03-15 Alza Corp Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
US6183434B1 (en) 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
CA2241615A1 (en) 1997-06-26 1998-12-26 An-Go-Gen Inc. Catheters
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
CA2352974A1 (en) * 1998-12-18 2000-06-22 John H. Livingston Insertion sets with micro-piercing members for use with medical devices and methods of using the same
ATE462468T1 (de) * 1999-06-04 2010-04-15 Georgia Tech Res Inst Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance

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EP1086718B1 (de) 2006-11-29
US20030199812A1 (en) 2003-10-23
DE60032082T2 (de) 2007-06-21
AU778234B2 (en) 2004-11-25
JP2001149485A (ja) 2001-06-05
US6960193B2 (en) 2005-11-01
AU5352800A (en) 2001-03-29
CA2315469C (en) 2009-04-21
ES2273639T3 (es) 2007-05-16
US20060047243A1 (en) 2006-03-02
ATE346644T1 (de) 2006-12-15
EP1086718A1 (de) 2001-03-28

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