DE1301812B - Verfahren zur Herstellung von Benzolsulfonylharnstoffen - Google Patents
Verfahren zur Herstellung von BenzolsulfonylharnstoffenInfo
- Publication number
- DE1301812B DE1301812B DEF46721A DEF0046721A DE1301812B DE 1301812 B DE1301812 B DE 1301812B DE F46721 A DEF46721 A DE F46721A DE F0046721 A DEF0046721 A DE F0046721A DE 1301812 B DE1301812 B DE 1301812B
- Authority
- DE
- Germany
- Prior art keywords
- ethyl
- benzenesulfonyl
- benzamido
- methoxy
- urea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (69)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEF46721A DE1301812B (de) | 1965-07-27 | 1965-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
NO162726A NO121834B (no) | 1965-07-27 | 1966-04-25 | |
IL26016A IL26016A (en) | 1965-07-27 | 1966-06-22 | Benzenesulfonyl-ureas and process for their manufacture |
BR181115/66A BR6681115D0 (pt) | 1965-07-27 | 1966-07-08 | Processo para a preparacao de benzenossulfonil-ureias |
US564743A US3454635A (en) | 1965-07-27 | 1966-07-13 | Benzenesulfonyl-ureas and process for their manufacture |
DK364466AA DK117419B (da) | 1965-07-27 | 1966-07-13 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
FI661889A FI45959C (fi) | 1965-07-27 | 1966-07-14 | Menetelmä suun kautta annettavien, veren sokeripitoisuutta alentavien bentseenisulfonyylivirtsa-aineiden valmistamiseksi. |
IT15327/66A IT1043760B (it) | 1965-07-27 | 1966-07-14 | Benzolsolfoniluree e processo per la loro preparazione |
IL26194A IL26194A (en) | 1965-07-27 | 1966-07-21 | Benzenesulfonyl-ureas and process for their manufacture |
LU51617D LU51617A1 (no) | 1965-07-27 | 1966-07-22 | |
IS1581A IS756B6 (is) | 1965-07-27 | 1966-07-22 | Framleiðsla benzensulfonyl-þvagefna. |
LU51616D LU51616A1 (no) | 1965-07-27 | 1966-07-22 | |
ES0329462A ES329462A1 (es) | 1965-07-27 | 1966-07-23 | Un procedimiento para la preparacion de bencenosulfonilureas |
AT711068A AT274840B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
AT824368A AT278032B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
GB33416/66A GB1149391A (en) | 1965-07-27 | 1966-07-25 | Benzenesulphonyl-ureas and process for their manufacture |
AT711268A AT274842B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
AT710868A AT274838B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
AT08244/68A AT279638B (no) | 1965-07-27 | 1966-07-25 | |
AT708266A AT275541B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
AT708166A AT274830B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
AT710968A AT274839B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
AT711168A AT274841B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur Herstellung von neuen Benzolsulfonylharnstoffen und deren Salzen |
GB33285/66A GB1153272A (en) | 1965-07-27 | 1966-07-25 | Benzenesulphonyl-Ureas and Process for their manufacture |
AT08242/68A AT278031B (de) | 1965-07-27 | 1966-07-25 | Verfahren zur herstellung von neuen benzolsulfonylharnstoffen und deren salzen |
NO164067A NO123569B (no) | 1965-07-27 | 1966-07-26 | |
IT17340/66A IT1043761B (it) | 1965-07-27 | 1966-07-26 | Benzolsolfoniluree e processo per la loro preparazione |
SE10158/66A SE328566B (no) | 1965-07-27 | 1966-07-26 | |
MC636A MC601A1 (fr) | 1965-07-27 | 1966-07-26 | Benzène-sulfonyl-urées et leur préparation |
IS1582A IS822B6 (is) | 1965-07-27 | 1966-07-26 | Aðferð til að framleiða benzonsulfonylþvagefni |
DK388766AA DK123652B (da) | 1965-07-27 | 1966-07-26 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf med baser. |
CH824269A CH508606A (de) | 1965-07-27 | 1966-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
JP41049301A JPS526985B1 (no) | 1965-07-27 | 1966-07-27 | |
BE684654D BE684654A (no) | 1965-07-27 | 1966-07-27 | |
BE684652D BE684652A (no) | 1965-07-27 | 1966-07-27 | |
CH1086166A CH478103A (de) | 1965-07-27 | 1966-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
NL6610580A NL6610580A (no) | 1965-07-27 | 1966-07-27 | |
BR181609/66A BR6681609D0 (pt) | 1965-07-27 | 1966-07-27 | Processo para a preparacao de benzenossulfanil-ureias |
FR71117A FR1487897A (fr) | 1965-07-27 | 1966-07-27 | Benzène-sulfonyl-urées et leur préparation |
CH824469A CH491095A (de) | 1965-07-27 | 1966-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
CH823969A CH491094A (de) | 1965-07-27 | 1966-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
CH824169A CH478104A (de) | 1965-07-27 | 1966-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
CH824369A CH478105A (de) | 1965-07-27 | 1966-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
CH824069A CH491881A (de) | 1965-07-27 | 1966-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
AT08241/68A AT279637B (de) | 1965-07-27 | 1966-08-31 | Verfahren zur herstellung von neuen benzolsulfonylharnstoffen und deren salzen |
FR81659A FR5943M (no) | 1965-07-27 | 1966-10-26 | |
ES344046A ES344046A1 (es) | 1965-07-27 | 1967-08-11 | Procedimiento para la obtencion de n-(4- (beta-<2-metoxi-5-clorobenzamido>-etil) -bencenosulfonil)-n'- (4-metil-ciclo- hexil) -urea. |
ES344044A ES344044A1 (es) | 1965-07-27 | 1967-08-11 | Procedimiento para la obtencion de bencenosulfonilureas. |
ES344045A ES344045A1 (es) | 1965-07-27 | 1967-08-11 | Procedimiento para la obtencion de n-(4 - (beta-<2-metoxi- 5 -cloro-benzamido>-etil)-bencenosulfonil)-n'-ciclohexil - urea. |
ES344047A ES344047A1 (es) | 1965-07-27 | 1967-08-11 | Procedimiento para la obtencion de n-(4-(beta- <2-metoxi- 5-bromobenzamido>-etil) - bencenosulfonil) -n'-(4-metilciclo-hexil)-urea. |
ES344048A ES344048A1 (es) | 1965-07-27 | 1967-08-11 | Procedimiento para la obtencion de n-(4-(beta-2-metoxi-5- metil-benzamido - etil)-benzolsulfonil) - n' - (4 metil-ci- clohexil)-urea. |
ES344049A ES344049A1 (es) | 1965-07-27 | 1967-08-11 | Procedimiento para la obtencion de n-(4-(beta-2-metoxi-4- cloro-benzamido>-etil)-bencenosulfonil)-n'-(4-metil-ciclohe-xil)-urea. |
ES355476A ES355476A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea. |
ES355480A ES355480A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea. |
ES355477A ES355477A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea. |
ES355478A ES355478A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea. |
ES355474A ES355474A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea. |
ES355479A ES355479A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- cloro-benzamido>-etil) -bencenosulfonil)-n'-ciclohexil-urea. |
ES355481A ES355481A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- cloro-benzamido>-etil)-bencenosulfonil)-n'-ciclohexil-urea. |
ES355475A ES355475A1 (es) | 1965-07-27 | 1968-06-26 | Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea. |
US813387A US3507954A (en) | 1965-07-27 | 1969-03-03 | Benzenesulfonyl-ureas as anti-diabetic agents |
CY53470A CY534A (en) | 1965-07-27 | 1970-04-07 | Benzenesulphonyl-ureas and process for their manufacture |
CY54070A CY540A (en) | 1965-07-27 | 1970-05-22 | Benzenesulphonyl-ureas and process for their manufacture |
MY1970111A MY7000111A (en) | 1965-07-27 | 1970-12-31 | Benzenesulphonyl-ureas and process for their manufacture |
MY197086A MY7000086A (en) | 1965-07-27 | 1970-12-31 | Benzenesulphonyl-ureas and process for their manufacture |
IN1912/CAL/74A IN139501B (no) | 1965-07-27 | 1974-08-24 | |
IN1917/CAL/74A IN139506B (no) | 1965-07-27 | 1974-08-24 | |
IN1914/CAL/74A IN139503B (no) | 1965-07-27 | 1974-08-24 | |
IN688/CAL/76A IN143078B (no) | 1965-07-27 | 1976-04-21 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEF46721A DE1301812B (de) | 1965-07-27 | 1965-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
Publications (1)
Publication Number | Publication Date |
---|---|
DE1301812B true DE1301812B (de) | 1969-08-28 |
Family
ID=7101195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DEF46721A Pending DE1301812B (de) | 1965-07-27 | 1965-07-27 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS526985B1 (no) |
AT (11) | AT275541B (no) |
BE (2) | BE684654A (no) |
BR (2) | BR6681115D0 (no) |
CH (1) | CH478103A (no) |
CY (2) | CY534A (no) |
DE (1) | DE1301812B (no) |
DK (2) | DK117419B (no) |
ES (15) | ES329462A1 (no) |
FI (1) | FI45959C (no) |
FR (1) | FR5943M (no) |
GB (2) | GB1149391A (no) |
IL (2) | IL26016A (no) |
IN (3) | IN139506B (no) |
IS (2) | IS756B6 (no) |
IT (2) | IT1043760B (no) |
LU (2) | LU51616A1 (no) |
MC (1) | MC601A1 (no) |
MY (2) | MY7000111A (no) |
NL (1) | NL6610580A (no) |
NO (2) | NO121834B (no) |
SE (1) | SE328566B (no) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0362704A1 (de) * | 1988-10-01 | 1990-04-11 | Hoechst Aktiengesellschaft | Verfahren zur Mikronisierung von Glibenclamid |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670901A1 (de) * | 1967-08-09 | 1971-03-18 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
-
1965
- 1965-07-27 DE DEF46721A patent/DE1301812B/de active Pending
-
1966
- 1966-04-25 NO NO162726A patent/NO121834B/no unknown
- 1966-06-22 IL IL26016A patent/IL26016A/xx unknown
- 1966-07-08 BR BR181115/66A patent/BR6681115D0/pt unknown
- 1966-07-13 DK DK364466AA patent/DK117419B/da unknown
- 1966-07-14 FI FI661889A patent/FI45959C/fi active
- 1966-07-14 IT IT15327/66A patent/IT1043760B/it active
- 1966-07-21 IL IL26194A patent/IL26194A/xx unknown
- 1966-07-22 LU LU51616D patent/LU51616A1/xx unknown
- 1966-07-22 IS IS1581A patent/IS756B6/is unknown
- 1966-07-22 LU LU51617D patent/LU51617A1/xx unknown
- 1966-07-23 ES ES0329462A patent/ES329462A1/es not_active Expired
- 1966-07-25 AT AT708266A patent/AT275541B/de active
- 1966-07-25 AT AT08242/68A patent/AT278031B/de not_active IP Right Cessation
- 1966-07-25 AT AT824368A patent/AT278032B/de not_active IP Right Cessation
- 1966-07-25 AT AT711268A patent/AT274842B/de active
- 1966-07-25 AT AT710868A patent/AT274838B/de active
- 1966-07-25 AT AT711168A patent/AT274841B/de active
- 1966-07-25 AT AT08244/68A patent/AT279638B/de not_active IP Right Cessation
- 1966-07-25 AT AT708166A patent/AT274830B/de active
- 1966-07-25 AT AT710968A patent/AT274839B/de active
- 1966-07-25 GB GB33416/66A patent/GB1149391A/en not_active Expired
- 1966-07-25 AT AT711068A patent/AT274840B/de active
- 1966-07-25 GB GB33285/66A patent/GB1153272A/en not_active Expired
- 1966-07-26 SE SE10158/66A patent/SE328566B/xx unknown
- 1966-07-26 IS IS1582A patent/IS822B6/is unknown
- 1966-07-26 DK DK388766AA patent/DK123652B/da unknown
- 1966-07-26 NO NO164067A patent/NO123569B/no unknown
- 1966-07-26 IT IT17340/66A patent/IT1043761B/it active
- 1966-07-26 MC MC636A patent/MC601A1/xx unknown
- 1966-07-27 JP JP41049301A patent/JPS526985B1/ja active Pending
- 1966-07-27 BE BE684654D patent/BE684654A/xx not_active IP Right Cessation
- 1966-07-27 BR BR181609/66A patent/BR6681609D0/pt unknown
- 1966-07-27 CH CH1086166A patent/CH478103A/de not_active IP Right Cessation
- 1966-07-27 BE BE684652D patent/BE684652A/xx not_active IP Right Cessation
- 1966-07-27 NL NL6610580A patent/NL6610580A/xx unknown
- 1966-08-31 AT AT08241/68A patent/AT279637B/de not_active IP Right Cessation
- 1966-10-26 FR FR81659A patent/FR5943M/fr not_active Expired
-
1967
- 1967-08-11 ES ES344048A patent/ES344048A1/es not_active Expired
- 1967-08-11 ES ES344044A patent/ES344044A1/es not_active Expired
- 1967-08-11 ES ES344047A patent/ES344047A1/es not_active Expired
- 1967-08-11 ES ES344049A patent/ES344049A1/es not_active Expired
- 1967-08-11 ES ES344046A patent/ES344046A1/es not_active Expired
- 1967-08-11 ES ES344045A patent/ES344045A1/es not_active Expired
-
1968
- 1968-06-26 ES ES355478A patent/ES355478A1/es not_active Expired
- 1968-06-26 ES ES355480A patent/ES355480A1/es not_active Expired
- 1968-06-26 ES ES355475A patent/ES355475A1/es not_active Expired
- 1968-06-26 ES ES355477A patent/ES355477A1/es not_active Expired
- 1968-06-26 ES ES355479A patent/ES355479A1/es not_active Expired
- 1968-06-26 ES ES355476A patent/ES355476A1/es not_active Expired
- 1968-06-26 ES ES355474A patent/ES355474A1/es not_active Expired
- 1968-06-26 ES ES355481A patent/ES355481A1/es not_active Expired
-
1970
- 1970-04-07 CY CY53470A patent/CY534A/xx unknown
- 1970-05-22 CY CY54070A patent/CY540A/xx unknown
- 1970-12-31 MY MY1970111A patent/MY7000111A/xx unknown
- 1970-12-31 MY MY197086A patent/MY7000086A/xx unknown
-
1974
- 1974-08-24 IN IN1917/CAL/74A patent/IN139506B/en unknown
- 1974-08-24 IN IN1914/CAL/74A patent/IN139503B/en unknown
- 1974-08-24 IN IN1912/CAL/74A patent/IN139501B/en unknown
Non-Patent Citations (1)
Title |
---|
None * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0362704A1 (de) * | 1988-10-01 | 1990-04-11 | Hoechst Aktiengesellschaft | Verfahren zur Mikronisierung von Glibenclamid |
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