CY1111985T1 - 5-μελεις, βασισμενοι σε ετεροκυκλο αναστολεις κινασης ρ38 - Google Patents

5-μελεις, βασισμενοι σε ετεροκυκλο αναστολεις κινασης ρ38

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Publication number
CY1111985T1
CY1111985T1 CY20111101022T CY111101022T CY1111985T1 CY 1111985 T1 CY1111985 T1 CY 1111985T1 CY 20111101022 T CY20111101022 T CY 20111101022T CY 111101022 T CY111101022 T CY 111101022T CY 1111985 T1 CY1111985 T1 CY 1111985T1
Authority
CY
Cyprus
Prior art keywords
kinase
hydrocycle
based model
model surface
disorders
Prior art date
Application number
CY20111101022T
Other languages
English (en)
Inventor
Olga M Fryszman
Hengyuan Lang
Jiong Lan
Edcon Chang
Yunfeng Fang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34108816&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1111985(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1111985T1 publication Critical patent/CY1111985T1/el

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Abstract

Παρέχονται 5-μελείς, βασισμένοι σε ετερόκυκλο, αναστολείς κινάσης p38. Επιπλέον, παρέχονται αναστολείς κινάσης p38, περιλαμβανομένης και της κινάσης p38α και p38β, βασισμένοι σε πυραζόλη και ιμιδαζόλη. Επίσης, παρέχονται φαρμακευτικές συνθέσεις οι οποίες περιέχουν τις ενώσεις. Μέθοδοι χρήσης των ενώσεων και των συνθέσεων περικλείονται επίσης, περιλαμβανομένης και μεθόδου για τη θεραπεία, την πρόληψη ή τη βελτίωση ενός ή περισσότερων συμπτωμάτων νόσων και διαταραχών που προκαλούνται από την κινάση p38, τα οποία περιλαμβάνουν, αλλά δεν περιορίζονται σε, τις φλεγμονώδεις νόσους και διαταραχές.
CY20111101022T 2003-06-26 2011-10-27 5-μελεις, βασισμενοι σε ετεροκυκλο αναστολεις κινασης ρ38 CY1111985T1 (el)

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