CY1106411T1 - Διαδepμικο θepαπευτικο συστημα με fentanyl - Google Patents

Διαδepμικο θepαπευτικο συστημα με fentanyl

Info

Publication number
CY1106411T1
CY1106411T1 CY20071100407T CY071100407T CY1106411T1 CY 1106411 T1 CY1106411 T1 CY 1106411T1 CY 20071100407 T CY20071100407 T CY 20071100407T CY 071100407 T CY071100407 T CY 071100407T CY 1106411 T1 CY1106411 T1 CY 1106411T1
Authority
CY
Cyprus
Prior art keywords
fentanyl
active substance
weight
saturation solubility
therapeutic system
Prior art date
Application number
CY20071100407T
Other languages
English (en)
Inventor
Walter Müller
Thomas Hille
Original Assignee
Lts Lohmann Therapie-Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7696568&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1106411(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lts Lohmann Therapie-Systeme Ag filed Critical Lts Lohmann Therapie-Systeme Ag
Publication of CY1106411T1 publication Critical patent/CY1106411T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η εφεύρεση αφορά σε ένα διαδερμικό θεραπευτικό σύστημα (TTS), που αποτελείται από ένα μη διαπερατό από την δραστική ουσία οπίσθιο στρώμα, τουλάχιστον ένα στρώμα μήτρας που περιέχει Fentanyl ή μία ανάλογη προς το Fentanyl δραστική ουσία με βάση πολυακρυλικό εστέρα και ένα προστατευτικό στρώμα που απομακρύνεται πριν την χρήση, το οποίο χαρακτηρίζεται από το γεγονός, ότι το πολυακρυλικό πολυμερές είναι αυτοκόλλητο και ελεύθερο από ομάδες καρβοξυλίου, εμφανίζει για το Fentanyl μία διαλυτότητα κορεσμού μεταξύ 3 και 20 % κατά βάρος, κατά προτίμηση μία διαλυτότητα κορεσμού μεταξύ 4 και 12% και κατά ιδιαίτερη προτίμηση μία διαλυτότητα κορεσμού μεταξύ 5 και 10 % κατά βάρος και ότι τα στρώματα που περιέχουν δραστική ουσία περιέχουν τουλάχιστον 80 % κατά βάρος της εισαχθείσας με κατεργασία δραστικής ουσίας σε μοριακά διάσπαρτη διαλυμένη μορφή.
CY20071100407T 2001-08-24 2007-03-22 Διαδepμικο θepαπευτικο συστημα με fentanyl CY1106411T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10141650A DE10141650C1 (de) 2001-08-24 2001-08-24 Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
PCT/EP2002/007664 WO2003018075A2 (de) 2001-08-24 2002-07-10 Transdermales therapeutisches system mit fentanyl bzw. verwandten substanzen

Publications (1)

Publication Number Publication Date
CY1106411T1 true CY1106411T1 (el) 2011-10-12

Family

ID=7696568

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100407T CY1106411T1 (el) 2001-08-24 2007-03-22 Διαδepμικο θepαπευτικο συστημα με fentanyl

Country Status (17)

Country Link
US (3) US10568845B2 (el)
EP (3) EP1418894B1 (el)
JP (2) JP5405709B2 (el)
KR (1) KR100895189B1 (el)
CN (2) CN1713899A (el)
AT (1) ATE352293T1 (el)
AU (1) AU2002328328B2 (el)
BR (1) BR0212026A (el)
CA (1) CA2457401C (el)
CY (1) CY1106411T1 (el)
DE (2) DE10141650C1 (el)
DK (1) DK1418894T3 (el)
ES (1) ES2280563T3 (el)
MX (1) MXPA04001676A (el)
PT (1) PT1418894E (el)
WO (1) WO2003018075A2 (el)
ZA (1) ZA200400314B (el)

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CA2457401C (en) 2010-09-07
EP1782799A2 (de) 2007-05-09
MXPA04001676A (es) 2004-05-31
JP5639843B2 (ja) 2014-12-10
ES2280563T3 (es) 2007-09-16
JP5405709B2 (ja) 2014-02-05
CN102258501A (zh) 2011-11-30
DK1418894T3 (da) 2007-04-10
CA2457401A1 (en) 2003-03-06
BR0212026A (pt) 2004-08-03
KR20040029007A (ko) 2004-04-03
US20040234584A1 (en) 2004-11-25
EP1825849A1 (de) 2007-08-29
US10940122B2 (en) 2021-03-09
ZA200400314B (en) 2004-11-01
US20200206148A1 (en) 2020-07-02
EP1418894A2 (de) 2004-05-19
EP1782799A3 (de) 2007-05-16
KR100895189B1 (ko) 2009-04-24
EP1418894B1 (de) 2007-01-24
CN1713899A (zh) 2005-12-28
DE10141650C1 (de) 2002-11-28
AU2002328328B2 (en) 2007-03-15
WO2003018075A2 (de) 2003-03-06
DE50209364D1 (en) 2007-03-15
US10568845B2 (en) 2020-02-25
JP2005501111A (ja) 2005-01-13
WO2003018075A3 (de) 2003-11-20
PT1418894E (pt) 2007-04-30
ATE352293T1 (de) 2007-02-15
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US20190262277A1 (en) 2019-08-29
US10583093B2 (en) 2020-03-10

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