CR20110701A - Derivados de pirazoles, su preparacion y su aplicacion terapeutica. - Google Patents

Derivados de pirazoles, su preparacion y su aplicacion terapeutica.

Info

Publication number
CR20110701A
CR20110701A CR20110701A CR20110701A CR20110701A CR 20110701 A CR20110701 A CR 20110701A CR 20110701 A CR20110701 A CR 20110701A CR 20110701 A CR20110701 A CR 20110701A CR 20110701 A CR20110701 A CR 20110701A
Authority
CR
Costa Rica
Prior art keywords
preparation
pirazoles
derivados
therapeutic application
therapeutic
Prior art date
Application number
CR20110701A
Other languages
English (en)
Inventor
Pierre-Yves Abecassis
Pascal Desmazeau
Michel Tabart
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of CR20110701A publication Critical patent/CR20110701A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms

Abstract

La presente invención se refiere a derivados de pirazoles, a su preparación y a su aplicación terapéutica.
CR20110701A 2009-07-03 2011-12-21 Derivados de pirazoles, su preparacion y su aplicacion terapeutica. CR20110701A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0903270A FR2947546B1 (fr) 2009-07-03 2009-07-03 Derives de pyrazoles, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
CR20110701A true CR20110701A (es) 2012-03-06

Family

ID=41695643

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20110701A CR20110701A (es) 2009-07-03 2011-12-21 Derivados de pirazoles, su preparacion y su aplicacion terapeutica.

Country Status (31)

Country Link
US (1) US8367715B2 (es)
EP (1) EP2448924B1 (es)
JP (1) JP5680640B2 (es)
KR (1) KR20120037967A (es)
CN (1) CN102471280B (es)
AR (1) AR077371A1 (es)
AU (1) AU2010267824A1 (es)
BR (1) BR112012000104A2 (es)
CA (1) CA2767096A1 (es)
CL (1) CL2012000013A1 (es)
CO (1) CO6480992A2 (es)
CR (1) CR20110701A (es)
DO (1) DOP2012000001A (es)
EA (1) EA020364B1 (es)
EC (2) ECSP12011659A (es)
FR (1) FR2947546B1 (es)
HK (1) HK1169387A1 (es)
IL (1) IL217300A0 (es)
MA (1) MA33500B1 (es)
MX (1) MX2012000267A (es)
MY (1) MY155829A (es)
NI (1) NI201200001A (es)
NZ (1) NZ597578A (es)
PE (1) PE20120917A1 (es)
SG (1) SG177463A1 (es)
TN (1) TN2011000658A1 (es)
TW (1) TWI471312B (es)
UA (1) UA106500C2 (es)
UY (1) UY32757A (es)
WO (1) WO2011001122A2 (es)
ZA (1) ZA201200027B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2908409B1 (fr) * 2006-11-10 2009-01-09 Sanofi Aventis Sa Pyrazoles substituees,compositions les contenant,procede de fabrication et utilisation
CA2862832A1 (en) * 2012-01-09 2013-07-18 X-Rx, Inc. Benzhydrol-pyrazole derivatives having kinase inhibitory activity and uses thereof
AR094812A1 (es) 2013-02-20 2015-08-26 Eisai R&D Man Co Ltd Derivado de piridina monocíclico como inhibidor del fgfr
KR102344105B1 (ko) 2014-08-18 2021-12-29 에자이 알앤드디 매니지먼트 가부시키가이샤 모노시클릭 피리딘 유도체의 염 및 이의 결정
CN107619388A (zh) * 2016-07-13 2018-01-23 南京天印健华医药科技有限公司 作为fgfr抑制剂的杂环化合物
CN107840842A (zh) 2016-09-19 2018-03-27 北京天诚医药科技有限公司 炔代杂环化合物、其制备方法及其在医药学上的应用
MX2020008610A (es) 2018-03-28 2020-09-21 Eisai R&D Man Co Ltd Agente terapeutico para carcinoma hepatocelular.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331541B1 (en) * 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
GB0317127D0 (en) * 2003-07-22 2003-08-27 Astex Technology Ltd Pharmaceutical compounds
MX2007008809A (es) * 2005-01-21 2007-09-07 Astex Therapeutics Ltd Combinaciones de inhibidores de pirazol cinasa y otros agentes antitumor.
KR101461680B1 (ko) * 2005-12-02 2014-11-19 바이엘 헬스케어 엘엘씨 과다-증식성 장애 및 맥관형성과 관련된 질환의 치료에유용한 치환된 4-아미노-피롤로트리아진 유도체
WO2007075377A2 (en) * 2005-12-15 2007-07-05 Cytokinetics, Inc. Certain chemical entities, compositions and methods
US20070208000A1 (en) * 2005-12-15 2007-09-06 Morgan Bradley P Certain chemical entities, compositions and methods
FR2908409B1 (fr) * 2006-11-10 2009-01-09 Sanofi Aventis Sa Pyrazoles substituees,compositions les contenant,procede de fabrication et utilisation
MX2009006170A (es) * 2006-12-11 2009-06-19 Irmc Llc Compuestos y composiciones como inhibidores de cinasa.

Also Published As

Publication number Publication date
UY32757A (es) 2011-01-31
JP2012531466A (ja) 2012-12-10
KR20120037967A (ko) 2012-04-20
UA106500C2 (uk) 2014-09-10
US8367715B2 (en) 2013-02-05
FR2947546B1 (fr) 2011-07-01
CA2767096A1 (fr) 2011-01-06
WO2011001122A2 (fr) 2011-01-06
BR112012000104A2 (pt) 2016-03-15
DOP2012000001A (es) 2012-01-31
TW201107298A (en) 2011-03-01
IL217300A0 (en) 2012-02-29
FR2947546A1 (fr) 2011-01-07
ZA201200027B (en) 2013-03-27
ECSP12011569A (es) 2012-02-29
CN102471280A (zh) 2012-05-23
CL2012000013A1 (es) 2012-09-14
CO6480992A2 (es) 2012-07-16
EP2448924B1 (fr) 2013-09-04
SG177463A1 (en) 2012-02-28
EA201270128A1 (ru) 2012-07-30
HK1169387A1 (en) 2013-01-25
NZ597578A (en) 2013-11-29
EA020364B1 (ru) 2014-10-30
PE20120917A1 (es) 2012-08-17
AU2010267824A1 (en) 2012-02-16
AR077371A1 (es) 2011-08-24
TWI471312B (zh) 2015-02-01
EP2448924A2 (fr) 2012-05-09
MA33500B1 (fr) 2012-08-01
MX2012000267A (es) 2012-04-30
US20120270918A1 (en) 2012-10-25
TN2011000658A1 (fr) 2013-05-24
CN102471280B (zh) 2014-08-06
ECSP12011659A (es) 2012-03-30
WO2011001122A3 (fr) 2011-02-24
NI201200001A (es) 2012-03-30
MY155829A (en) 2015-12-15
JP5680640B2 (ja) 2015-03-04

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