DK2442870T3 - Pyrazinooxazepin-derivater. - Google Patents

Pyrazinooxazepin-derivater.

Info

Publication number: DK2442870T3
Authority: DK; Denmark
Prior art keywords: pyrazinooxazepin; derivatives; pyrazinooxazepin derivatives
Prior art date: 2009-06-15

Application number

DK10727154.6T

Other languages

English (en)

Inventor

Shigekazu Sasaki

Tomokazu Kusumoto

Izumi Nomura

Hironobu Maezaki

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-06-15

Filing date

2010-06-14

Publication date

2014-06-30

2010-06-14 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2014-06-30 Application granted granted Critical

2014-06-30 Publication of DK2442870T3 publication Critical patent/DK2442870T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Hematology (AREA)
Surgery (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK10727154.6T 2009-06-15 2010-06-14 Pyrazinooxazepin-derivater. DK2442870T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2009142673		2009-06-15
PCT/JP2010/060408 WO2010147226A1 (en)	2009-06-15	2010-06-14	Pyrazinooxazepine derivatives

Publications (1)

Publication Number	Publication Date
DK2442870T3 true DK2442870T3 (da)	2014-06-30

Family

ID=42561089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK10727154.6T DK2442870T3 (da)	2009-06-15	2010-06-14	Pyrazinooxazepin-derivater.

Country Status (41)

Country	Link
US (4)	US9115139B2 (da)
EP (1)	EP2442870B1 (da)
JP (2)	JP5579262B2 (da)
KR (1)	KR101768234B1 (da)
CN (1)	CN102458579B (da)
AR (1)	AR077094A1 (da)
AU (1)	AU2010260847B2 (da)
BR (1)	BRPI1011502A2 (da)
CA (1)	CA2765239C (da)
CL (1)	CL2011003154A1 (da)
CO (1)	CO6491037A2 (da)
CR (1)	CR20120021A (da)
CY (1)	CY1115483T1 (da)
DK (1)	DK2442870T3 (da)
DO (1)	DOP2011000393A (da)
EA (1)	EA021079B1 (da)
EC (1)	ECSP12011603A (da)
ES (1)	ES2480275T3 (da)
GE (1)	GEP20146168B (da)
HK (1)	HK1169623A1 (da)
HR (1)	HRP20140589T1 (da)
IL (1)	IL216761A (da)
JO (1)	JO3087B1 (da)
MA (1)	MA33430B1 (da)
ME (1)	ME01835B (da)
MX (1)	MX2011013081A (da)
MY (1)	MY157497A (da)
NZ (1)	NZ597507A (da)
PE (1)	PE20121049A1 (da)
PL (1)	PL2442870T3 (da)
PT (1)	PT2442870E (da)
RS (1)	RS53414B (da)
SG (1)	SG176696A1 (da)
SI (1)	SI2442870T1 (da)
SM (1)	SMT201400080B (da)
TN (1)	TN2011000630A1 (da)
TW (2)	TWI542592B (da)
UA (1)	UA108357C2 (da)
UY (1)	UY32707A (da)
WO (1)	WO2010147226A1 (da)
ZA (1)	ZA201109370B (da)

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JP5528699B2 (ja) *	2006-05-16	2014-06-25	武田薬品工業株式会社	縮合複素環化合物およびその用途
KR101768234B1 (ko) *	2009-06-15	2017-08-14	다케다 야쿠힌 고교 가부시키가이샤	피라지노옥사제핀 유도체
US20130267500A1 (en)	2010-09-01	2013-10-10	Arena Pharmaceuticals, Inc.	5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
JP2014201578A (ja) *	2013-04-09	2014-10-27	武田薬品工業株式会社	線維筋痛症治療剤
JP2014214132A (ja) *	2013-04-26	2014-11-17	武田薬品工業株式会社	ニコチン依存症の予防・治療剤
WO2015066344A1 (en)	2013-11-01	2015-05-07	Arena Pharmaceuticals, Inc.	5-ht2c receptor agonists and compositions and methods of use
WO2017026538A1 (en)	2015-08-07	2017-02-16	Takeda Pharmaceutical Company Limited	Production method of pyrazine
WO2017111178A1 (en) *	2015-12-24	2017-06-29	Takeda Pharmaceutical Company Limited	Solid preparation
US9985579B2 (en)	2016-04-12	2018-05-29	Preformed Line Products Co.	Mounting assembly for mounting a solar panel
JPWO2019131902A1 (ja) *	2017-12-27	2020-12-10	武田薬品工業株式会社	腹圧性尿失禁および便失禁の治療薬

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JP2992677B2 (ja)	1995-06-05	1999-12-20	武田薬品工業株式会社	骨形成促進医薬組成物
SE0002754D0 (sv)	2000-07-21	2000-07-21	Pharmacia & Upjohn Ab	New pharmaceutical combination formulation and method of treatment with the combination
DE60139021D1 (de)	2000-11-20	2009-07-30	Biovitrum Ab Publ	Piperazinylpyrazinverbindungen als antagonisten des serotonin-5-ht2-rezeptors
US6699866B2 (en)	2001-04-17	2004-03-02	Sepracor Inc.	Thiazole and other heterocyclic ligands for mammalian dopamine, muscarinic and serotonin receptors and transporters, and methods of use thereof
SE0201544D0 (sv)	2002-05-17	2002-05-17	Biovitrum Ab	Novel compounds and thier use
AU2003243089B2 (en)	2002-06-19	2010-01-07	Biovitrum Ab (Publ)	Novel compounds, their use and preparation
DE60321606D1 (de)	2002-06-19	2008-07-24	Biovitrum Ab Publ	Piperazinylpyrazine als Modulatoren des Serotonin 5-HT2C Rezeptors
US7625887B2 (en)	2003-01-28	2009-12-01	Takeda Pharmaceutical Company Limited	Receptor agonists
CL2004000826A1 (es)	2003-04-25	2005-03-04	Pfizer	Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129
EP2189448B1 (en)	2003-06-17	2014-01-29	Arena Pharmaceuticals, Inc.	Processes for the Separation of 3-Benzazepine Racemates
NZ578503A (en)	2003-06-17	2011-02-25	Arena Pharm Inc	Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
JP2006056881A (ja)	2004-07-21	2006-03-02	Takeda Chem Ind Ltd	縮合環化合物
SI1926712T1 (sl)	2005-09-01	2010-01-29	Lilly Co Eli	6-substituirani 2,3.4,5-tetrahidro-1h-benzo(d)azepini kot agonisti 5-ht2c receptorja
FR2895259B1 (fr)	2005-12-22	2008-02-22	Urosphere Sas	Methodes de traitement des incontinences urinaires
JP5528699B2 (ja) *	2006-05-16	2014-06-25	武田薬品工業株式会社	縮合複素環化合物およびその用途
WO2008108445A1 (ja) *	2007-03-07	2008-09-12	Takeda Pharmaceutical Company Limited	ベンゾオキサゼピン誘導体およびその用途
US20090062253A1 (en) *	2007-08-31	2009-03-05	Kalypsys, Inc.	Heterocyclodiazepine cannabinoid receptor modulators for treatment of disease
WO2009063993A1 (ja) *	2007-11-15	2009-05-22	Takeda Pharmaceutical Company Limited	縮合ピリジン誘導体およびその用途
WO2009063991A1 (ja) *	2007-11-15	2009-05-22	Takeda Pharmaceutical Company Limited	ピリドオキサゼピン誘導体およびその用途
EP2789338A3 (en)	2007-11-15	2015-01-14	Takeda Pharmaceutical Company Limited	Condensed pyridine derivate and use thereof
US8299103B2 (en)	2009-06-15	2012-10-30	Boehringer Ingelheim International Gmbh	Compounds which selectively modulate the CB2 receptor
KR101768234B1 (ko) *	2009-06-15	2017-08-14	다케다 야쿠힌 고교 가부시키가이샤	피라지노옥사제핀 유도체

2010
- 2010-06-14 KR KR1020127000935A patent/KR101768234B1/ko active IP Right Grant
- 2010-06-14 GE GEAP201012529A patent/GEP20146168B/en unknown
- 2010-06-14 MY MYPI2011006107A patent/MY157497A/en unknown
- 2010-06-14 ME MEP-2014-81A patent/ME01835B/me unknown
- 2010-06-14 WO PCT/JP2010/060408 patent/WO2010147226A1/en active Application Filing
- 2010-06-14 JP JP2012514674A patent/JP5579262B2/ja not_active Expired - Fee Related
- 2010-06-14 SG SG2011090149A patent/SG176696A1/en unknown
- 2010-06-14 RS RS20140373A patent/RS53414B/en unknown
- 2010-06-14 UA UAA201200408A patent/UA108357C2/ru unknown
- 2010-06-14 SI SI201030641T patent/SI2442870T1/sl unknown
- 2010-06-14 BR BRPI1011502A patent/BRPI1011502A2/pt not_active Application Discontinuation
- 2010-06-14 CA CA2765239A patent/CA2765239C/en not_active Expired - Fee Related
- 2010-06-14 UY UY0001032707A patent/UY32707A/es not_active Application Discontinuation
- 2010-06-14 AU AU2010260847A patent/AU2010260847B2/en not_active Ceased
- 2010-06-14 PE PE2011002104A patent/PE20121049A1/es active IP Right Grant
- 2010-06-14 PT PT107271546T patent/PT2442870E/pt unknown
- 2010-06-14 NZ NZ597507A patent/NZ597507A/xx not_active IP Right Cessation
- 2010-06-14 TW TW099119242A patent/TWI542592B/zh not_active IP Right Cessation
- 2010-06-14 EA EA201270017A patent/EA021079B1/ru not_active IP Right Cessation
- 2010-06-14 US US13/377,918 patent/US9115139B2/en not_active Expired - Fee Related
- 2010-06-14 US US12/814,692 patent/US8318722B2/en not_active Expired - Fee Related
- 2010-06-14 PL PL10727154T patent/PL2442870T3/pl unknown
- 2010-06-14 MX MX2011013081A patent/MX2011013081A/es active IP Right Grant
- 2010-06-14 JO JOP/2010/0194A patent/JO3087B1/ar active
- 2010-06-14 ES ES10727154.6T patent/ES2480275T3/es active Active
- 2010-06-14 CN CN201080036178.1A patent/CN102458579B/zh not_active Expired - Fee Related
- 2010-06-14 EP EP10727154.6A patent/EP2442870B1/en active Active
- 2010-06-14 AR ARP100102101A patent/AR077094A1/es not_active Application Discontinuation
- 2010-06-14 TW TW104112674A patent/TW201529584A/zh unknown
- 2010-06-14 MA MA34535A patent/MA33430B1/fr unknown
- 2010-06-14 DK DK10727154.6T patent/DK2442870T3/da active
2011
- 2011-07-28 US US13/192,845 patent/US8314088B2/en not_active Expired - Fee Related
- 2011-07-28 US US13/192,865 patent/US8324201B2/en not_active Expired - Fee Related
- 2011-12-04 IL IL216761A patent/IL216761A/en not_active IP Right Cessation
- 2011-12-08 TN TNP2011000630A patent/TN2011000630A1/en unknown
- 2011-12-14 CL CL2011003154A patent/CL2011003154A1/es unknown
- 2011-12-14 DO DO2011000393A patent/DOP2011000393A/es unknown
- 2011-12-20 ZA ZA2011/09370A patent/ZA201109370B/en unknown
2012
- 2012-01-13 EC ECSP12011603 patent/ECSP12011603A/es unknown
- 2012-01-13 CO CO12004620A patent/CO6491037A2/es active IP Right Grant
- 2012-01-13 CR CR20120021A patent/CR20120021A/es unknown
- 2012-01-31 JP JP2012019274A patent/JP5579203B2/ja not_active Expired - Fee Related
- 2012-10-19 HK HK12110450.8A patent/HK1169623A1/xx not_active IP Right Cessation
2014
- 2014-06-23 HR HRP20140589AT patent/HRP20140589T1/hr unknown
- 2014-06-25 SM SM201400080T patent/SMT201400080B/xx unknown
- 2014-07-11 CY CY20141100527T patent/CY1115483T1/el unknown

Also Published As

Publication number	Publication date
KR101768234B1 (ko)	2017-08-14
ES2480275T3 (es)	2014-07-25
AU2010260847A1 (en)	2012-01-19
JP2012107032A (ja)	2012-06-07
SI2442870T1 (sl)	2014-07-31
MY157497A (en)	2016-06-15
SMT201400080B (it)	2014-09-08
MA33430B1 (fr)	2012-07-03
GEP20146168B (en)	2014-09-25
IL216761A (en)	2016-03-31
CA2765239C (en)	2018-08-07
US20120135979A1 (en)	2012-05-31
KR20120034734A (ko)	2012-04-12
EA021079B1 (ru)	2015-03-31
US8314088B2 (en)	2012-11-20
HK1169623A1 (en)	2013-02-01
ECSP12011603A (es)	2012-03-30
DOP2011000393A (es)	2012-02-15
ME01835B (me)	2014-12-20
US9115139B2 (en)	2015-08-25
JP5579203B2 (ja)	2014-08-27
CO6491037A2 (es)	2012-07-31
UA108357C2 (xx)	2015-04-27
BRPI1011502A2 (pt)	2016-03-22
EP2442870A1 (en)	2012-04-25
SG176696A1 (en)	2012-01-30
US8318722B2 (en)	2012-11-27
UY32707A (es)	2011-01-31
TW201529584A (zh)	2015-08-01
JP2012530051A (ja)	2012-11-29
ZA201109370B (en)	2012-10-31
AR077094A1 (es)	2011-08-03
PE20121049A1 (es)	2012-08-22
HRP20140589T1 (hr)	2014-08-01
US8324201B2 (en)	2012-12-04
CY1115483T1 (el)	2017-01-04
US20110282054A1 (en)	2011-11-17
CN102458579A (zh)	2012-05-16
JP5579262B2 (ja)	2014-08-27
US20100317651A1 (en)	2010-12-16
NZ597507A (en)	2013-09-27
TW201109338A (en)	2011-03-16
US20110288291A1 (en)	2011-11-24
EA201270017A1 (ru)	2012-07-30
TN2011000630A1 (en)	2013-05-24
EP2442870B1 (en)	2014-04-16
CN102458579B (zh)	2014-11-05
TWI542592B (zh)	2016-07-21
PT2442870E (pt)	2014-07-16
WO2010147226A1 (en)	2010-12-23
PL2442870T3 (pl)	2014-12-31
RS53414B (en)	2014-12-31
CR20120021A (es)	2012-03-06
CA2765239A1 (en)	2010-12-23
AU2010260847B2 (en)	2016-11-24
CL2011003154A1 (es)	2012-06-15
IL216761A0 (en)	2012-02-29
JO3087B1 (ar)	2017-03-15
MX2011013081A (es)	2012-01-20

Publication	Publication Date	Title
NO2021006I1 (no)	2021-02-15	Quofenix, delafloksacin
BRPI1013246A2 (pt)	2016-04-05	derivados de benzofuralina
BR112012002828A2 (pt)	2015-10-13	derivados de 5-fluorpirimidinona
BRPI1010301A2 (pt)	2016-03-15	composição.
DK2462134T3 (da)	2014-08-11	N1-sulfonyl-5-fluorpyrimidinonderivater
ECSP12011999A (es)	2012-07-31	Derivados benzamida sustituidos
DK2308877T3 (da)	2014-04-22	Imidazopyridin-2-on-derivater
BRPI1008774A2 (pt)	2016-03-08	espiroamida substituída
BRPI1011134A2 (pt)	2018-02-06	turbomáquina.
DK2397480T3 (da)	2013-09-02	Diazepindionderivat
BRPI1013844A2 (pt)	2016-04-12	derivados de piridina-isoxazol
BRPI1016117A2 (pt)	2016-04-12	derivados de isoxazol-isoxazol e isoxasol-isotiazol.
UY33125A (es)	2011-07-29	Diaza-espiro-[5,5]-undecanos
DK2344471T3 (da)	2013-10-07	7-piperidinalkyl-3,4-dihydroquinolon-derivat
DK2275414T3 (da)	2015-06-22	Cyclopentylacrylamidderivat
BRPI1014454A2 (pt)	2016-04-05	derivados de isoxazol-pirazol
BRPI0917446A2 (pt)	2015-12-22	derivados de acilaminobenzamida.
DK2387580T3 (da)	2014-10-13	Deoxyactagardinderivater
DK2442870T3 (da)	2014-06-30	Pyrazinooxazepin-derivater.
BR112012004964A2 (pt)	2016-04-05	girocóptero
BRPI1008070A2 (pt)	2016-03-15	tricianoboratos
BRPI1016192A2 (pt)	2016-04-19	derivados de soxazol.
IT1396487B1 (it)	2012-12-14	Convogliatore.
BRPI0906714A2 (pt)	2015-06-30	Derivados de oxazepinopirimidona heteroarilamida substituídos.
BR112012002810A2 (pt)	2015-09-15	derivados de n1-acil-5-fluoropirimidinona