RU2551963C2
(ru)
*
|
2010-09-09 |
2015-06-10 |
Пфайзер Инк. |
Молекулы, связывающиеся с 4-1вв
|
CA3019531A1
(en)
*
|
2011-04-19 |
2012-10-26 |
Pfizer Inc. |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
CN107964042B
(zh)
|
2012-05-30 |
2022-04-19 |
中外制药株式会社 |
靶组织特异性抗原结合分子
|
US9834610B2
(en)
*
|
2013-01-31 |
2017-12-05 |
Thomas Jefferson University |
Fusion proteins for modulating regulatory and effector T cells
|
ES2935257T3
(es)
|
2013-03-15 |
2023-03-03 |
Univ Chicago |
Métodos y composiciones relacionadas con la actividad de las células T
|
EP3783017A1
(en)
|
2013-04-02 |
2021-02-24 |
Chugai Seiyaku Kabushiki Kaisha |
Fc region variant
|
CA2925421C
(en)
|
2013-09-24 |
2023-08-29 |
Medicenna Therapeutics, Inc. |
Interleukin-2 fusion proteins and uses thereof
|
US20160264670A1
(en)
*
|
2013-11-06 |
2016-09-15 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens and combinations thereof
|
AU2014358191B2
(en)
|
2013-12-04 |
2020-12-24 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules
|
SG11201605097SA
(en)
|
2013-12-24 |
2016-07-28 |
Bristol Myers Squibb Co |
Tricyclic compounds as anticancer agents
|
US10899840B2
(en)
|
2014-02-04 |
2021-01-26 |
Pfizer Inc. |
Combination of a PD-1 antagonist and a 4-1BB agonist for treating cancer
|
KR101503341B1
(ko)
|
2014-03-12 |
2015-03-18 |
국립암센터 |
자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법
|
JP6592505B2
(ja)
|
2014-04-24 |
2019-10-16 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
インターロイキン−2のスーパーアンタゴニスト、パーシャルアゴニスト及びアンタゴニスト
|
KR20170004006A
(ko)
*
|
2014-05-21 |
2017-01-10 |
화이자 인코포레이티드 |
암을 치료하기 위한 항-ccr4 항체 및 4-1bb 효능제의 조합
|
ES2755395T3
(es)
|
2014-06-06 |
2020-04-22 |
Bristol Myers Squibb Co |
Anticuerpos contra el receptor del factor de necrosis tumoral inducido por glucocorticoides (GITR) y usos de los mismos
|
MX2016015610A
(es)
|
2014-06-06 |
2017-07-13 |
Flexus Biosciences Inc |
Agentes inmunorreguladores.
|
CA2955676A1
(en)
|
2014-08-25 |
2016-03-03 |
Pfizer Inc. |
Combination of a pd-1 antagonist and an alk inhibitor for treating cancer
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
EP3215141A4
(en)
|
2014-11-05 |
2018-06-06 |
Flexus Biosciences, Inc. |
Immunoregulatory agents
|
UY36391A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen
|
US10100129B2
(en)
|
2014-11-21 |
2018-10-16 |
Bristol-Myers Squibb Company |
Antibodies against CD73 and uses thereof
|
TW201630907A
(zh)
|
2014-12-22 |
2016-09-01 |
必治妥美雅史谷比公司 |
TGFβR拮抗劑
|
SG11201705116SA
(en)
|
2015-01-20 |
2017-08-30 |
Igm Biosciences Inc |
Tumor necrosis factor (tnf) superfamily receptor binding molecules and uses thereof
|
WO2016127052A1
(en)
|
2015-02-05 |
2016-08-11 |
Bristol-Myers Squibb Company |
Cxcl11 and smica as predictive biomarkers for efficacy of anti-ctla4 immunotherapy
|
TW201632559A
(zh)
*
|
2015-02-22 |
2016-09-16 |
索倫多醫療公司 |
結合cd137之抗體治療劑
|
CN107405401B
(zh)
|
2015-02-26 |
2022-02-01 |
默克专利股份公司 |
用于治疗癌症的pd-1/pd-l1抑制剂
|
US9884868B2
(en)
|
2015-03-02 |
2018-02-06 |
Rigel Pharmaceuticals, Inc. |
TGF-beta inhibitors
|
BR112017020999A2
(pt)
|
2015-04-03 |
2018-07-03 |
Bristol-Myers Squibb Company |
inibidores de indolamina-2,3-dioxigenase para o tratamento de câncer
|
TW201642897A
(zh)
|
2015-04-08 |
2016-12-16 |
F 星生物科技有限公司 |
Her2結合劑治療
|
LT3283527T
(lt)
|
2015-04-13 |
2021-03-25 |
Five Prime Therapeutics, Inc. |
Kompleksinė terapija vėžio gydymui
|
WO2016183114A1
(en)
|
2015-05-11 |
2016-11-17 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
US9725449B2
(en)
|
2015-05-12 |
2017-08-08 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
US10174024B2
(en)
|
2015-05-12 |
2019-01-08 |
Bristol-Myers Squibb Company |
5H-pyrido[3,2-B]indole compounds as anticancer agents
|
ES2938525T3
(es)
*
|
2015-05-18 |
2023-04-12 |
Pieris Pharmaceuticals Gmbh |
Polipéptido de fusión anticanceroso
|
MX2017014699A
(es)
*
|
2015-05-21 |
2018-04-11 |
Alligator Bioscience Ab |
Polipeptidos novedosos.
|
GB201509338D0
(en)
|
2015-05-29 |
2015-07-15 |
Bergenbio As |
Combination therapy
|
SG10202008304TA
(en)
|
2015-05-29 |
2020-10-29 |
Bristol Myers Squibb Co |
Antibodies against ox40 and uses thereof
|
EP3310810A1
(en)
|
2015-06-16 |
2018-04-25 |
Merck Patent GmbH |
Pd-l1 antagonist combination treatments
|
US10786547B2
(en)
|
2015-07-16 |
2020-09-29 |
Biokine Therapeutics Ltd. |
Compositions, articles of manufacture and methods for treating cancer
|
KR20180034548A
(ko)
|
2015-07-28 |
2018-04-04 |
브리스톨-마이어스 스큅 컴퍼니 |
Tgf 베타 수용체 길항제
|
WO2017025871A1
(en)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
WO2017035118A1
(en)
|
2015-08-25 |
2017-03-02 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
US10875926B2
(en)
|
2015-09-22 |
2020-12-29 |
Dingfu Biotarget Co., Ltd. |
Fully human antibody against human CD 137
|
US10149887B2
(en)
|
2015-10-23 |
2018-12-11 |
Canbas Co., Ltd. |
Peptides and peptidomimetics in combination with t cell activating and/or checkpoint inhibiting agents for cancer treatment
|
PE20181300A1
(es)
|
2015-11-02 |
2018-08-09 |
Five Prime Therapeutics Inc |
Polipeptidos del dominio extracelular de cd80 y su uso en el tratamiento del cancer
|
US10894830B2
(en)
|
2015-11-03 |
2021-01-19 |
Janssen Biotech, Inc. |
Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and their uses
|
GB201519481D0
(en)
|
2015-11-04 |
2015-12-16 |
Cancer Rec Tech Ltd |
Immunomodulatory antibodies
|
SG11201803817PA
(en)
|
2015-11-19 |
2018-06-28 |
Bristol Myers Squibb Co |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
CA3004794A1
(en)
|
2015-11-23 |
2017-06-01 |
Five Prime Therapeutics, Inc. |
Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment
|
EP3390406A1
(en)
|
2015-12-15 |
2018-10-24 |
Bristol-Myers Squibb Company |
Cxcr4 receptor antagonists
|
EP3402823A4
(en)
*
|
2016-01-11 |
2019-09-18 |
Inhibrx, Inc. |
MULTIVALENT AND MULTISPECIFIC 41BB BINDING FUSION PROTEINS
|
BR112018014016A2
(pt)
|
2016-01-25 |
2019-02-05 |
Pfizer |
combinação de um agonista de ox40 e um agonista de anticorpo monoclonal 4-1bb para tratamento de câncer
|
BR112018067368A2
(pt)
|
2016-03-04 |
2019-01-15 |
Bristol-Myers Squibb Company |
terapia de combinação com anticorpos anti-cd73
|
WO2017184619A2
(en)
|
2016-04-18 |
2017-10-26 |
Celldex Therapeutics, Inc. |
Agonistic antibodies that bind human cd40 and uses thereof
|
WO2017192811A1
(en)
|
2016-05-04 |
2017-11-09 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
JP2019516682A
(ja)
|
2016-05-04 |
2019-06-20 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法
|
EP3452452A4
(en)
|
2016-05-04 |
2019-10-30 |
Bristol-Myers Squibb Company |
INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE AND METHOD FOR THEIR USE
|
JP2019516687A
(ja)
|
2016-05-04 |
2019-06-20 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法
|
JP2019519485A
(ja)
|
2016-05-04 |
2019-07-11 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法
|
EP3464367B1
(en)
|
2016-05-27 |
2020-09-09 |
AbbVie Biotherapeutics Inc. |
Bispecific binding proteins binding an immunomodulatory protein and a tumor antigen
|
US10875921B2
(en)
|
2016-05-27 |
2020-12-29 |
Abbvie Biotherapeutics Inc. |
Anti-4-1BB antibodies and their uses
|
KR20230066647A
(ko)
|
2016-06-17 |
2023-05-16 |
마젠타 테라퓨틱스 인코포레이티드 |
Cd117+ 세포의 고갈을 위한 조성물 및 방법
|
CN109475603B
(zh)
|
2016-06-20 |
2023-06-13 |
科马布有限公司 |
抗pd-l1抗体
|
MY200602A
(en)
|
2016-07-14 |
2024-01-04 |
Bristol Myers Squibb Co |
Antibodies against tim3 and uses thereof
|
EA201990293A1
(ru)
|
2016-07-14 |
2019-07-31 |
Генмаб А/С |
Мультиспецифичные антитела против cd40 и cd137
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
US20190292179A1
(en)
|
2016-07-21 |
2019-09-26 |
Bristol-Myers Squibb Company |
TGF Beta RECEPTOR ANTAGONISTS
|
US10669344B2
(en)
|
2016-08-12 |
2020-06-02 |
Janssen Biotech, Inc. |
Engineered antibodies and other Fc-domain containing molecules with enhanced agonism and effector functions
|
MA45941A
(fr)
|
2016-08-12 |
2019-06-19 |
Janssen Biotech Inc |
Anticorps de membres de la superfamille anti-tnfr modifiés par fc ayant une activité agoniste améliorée et leurs procédés d'utilisation
|
WO2018035046A1
(en)
|
2016-08-15 |
2018-02-22 |
President And Fellows Of Harvard College |
Treating infections using idsd from proteus mirabilis
|
MY194032A
(en)
|
2016-08-17 |
2022-11-09 |
Compugen Ltd |
Anti-tigit antibodies, anti-pvrig antibodies and combinations thereof
|
CN106244611B
(zh)
*
|
2016-08-23 |
2019-05-17 |
浙江普康生物技术股份有限公司 |
一种细胞免疫佐剂tsa-41的制备方法及应用
|
US11351164B2
(en)
|
2016-08-26 |
2022-06-07 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
NZ751956A
(en)
|
2016-09-23 |
2022-01-28 |
Merus Nv |
Binding molecules that modulate a biological activity expressed by a cell
|
EP3522923A1
(en)
|
2016-10-06 |
2019-08-14 |
Pfizer Inc |
Dosing regimen of avelumab for the treatment of cancer
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
US10660909B2
(en)
|
2016-11-17 |
2020-05-26 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists
|
JP7274417B2
(ja)
*
|
2016-11-23 |
2023-05-16 |
イミュノア・セラピューティクス・インコーポレイテッド |
4-1bb結合タンパク質及びその使用
|
US11512134B2
(en)
|
2017-08-01 |
2022-11-29 |
Eli Lilly And Company |
Anti-CD137 antibodies
|
WO2018132279A1
(en)
|
2017-01-05 |
2018-07-19 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
ES2905890T3
(es)
*
|
2017-01-06 |
2022-04-12 |
Eutilex Co Ltd |
Anticuerpos anti-4-1BB humano y usos de los mismos
|
TW201837168A
(zh)
|
2017-01-06 |
2018-10-16 |
美商艾歐凡斯生物治療公司 |
以腫瘤壞死因子受體超家族(tnfrsf)促效劑使腫瘤浸潤淋巴球(til)擴增及til與tnfrsf促效劑的治療組合
|
US11566077B2
(en)
|
2017-01-17 |
2023-01-31 |
The University Of Chicago |
Dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment
|
WO2018134787A2
(en)
|
2017-01-20 |
2018-07-26 |
Magenta Therapeutics, Inc. |
Compositions and methods for the depletion of cd137+ cells
|
PL3570844T3
(pl)
|
2017-01-20 |
2024-02-26 |
Arcus Biosciences, Inc. |
Azolopirymidyna do leczenia zaburzeń związanych z nowotworami
|
CA3053222A1
(en)
|
2017-02-10 |
2018-08-16 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
KR102585848B1
(ko)
|
2017-02-24 |
2023-10-11 |
마크로제닉스, 인크. |
Cd137 및 종양 항원에 결합할 수 있는 이중특이적 결합 분자, 및 그것의 용도
|
US20200031944A1
(en)
|
2017-03-31 |
2020-01-30 |
Five Prime Therapeutics, Inc. |
Combination therapy for cancer using anti-gitr antibodies
|
CA3059366A1
(en)
|
2017-04-13 |
2018-10-18 |
Agenus Inc. |
Anti-cd137 antibodies and methods of use thereof
|
CA3059939A1
(en)
|
2017-04-21 |
2018-10-25 |
Kyn Therapeutics |
Indole ahr inhibitors and uses thereof
|
AU2018258661A1
(en)
|
2017-04-28 |
2019-10-17 |
Five Prime Therapeutics, Inc. |
Methods of treatment with CD80 extracellular domain polypeptides
|
US11066392B2
(en)
|
2017-05-12 |
2021-07-20 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
WO2018213377A1
(en)
|
2017-05-17 |
2018-11-22 |
Arcus Biosciences, Inc. |
Quinazoline-pyrazole derivatives for the treatment of cancer-related disorders
|
US11225523B2
(en)
|
2017-06-01 |
2022-01-18 |
Compugen Ltd. |
Triple combination antibody therapies
|
WO2018226714A1
(en)
|
2017-06-05 |
2018-12-13 |
Iovance Biotherapeutics, Inc. |
Methods of using tumor infiltrating lymphocytes in double-refractory melanoma
|
WO2018226336A1
(en)
|
2017-06-09 |
2018-12-13 |
Providence Health & Services - Oregon |
Utilization of cd39 and cd103 for identification of human tumor reactive cells for treatment of cancer
|
EP3641814A4
(en)
|
2017-06-19 |
2021-06-23 |
Medicenna Therapeutics Inc. |
USES AND METHODS FOR IL-2 SUPERAGONISTS, AGONISTS, AND FUSIONS THEREOF
|
CN116769035A
(zh)
*
|
2017-06-25 |
2023-09-19 |
西雅图免疫公司 |
抗4-1bb抗体及其制备和使用方法
|
BR112019027259A2
(pt)
|
2017-06-30 |
2020-07-14 |
Bristol-Myers Squibb Company |
formas amorfas e cristalinas de inibidores da ido
|
NZ760841A
(en)
|
2017-07-11 |
2024-02-23 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
EP3655439A1
(en)
|
2017-07-20 |
2020-05-27 |
Aptevo Research and Development LLC |
Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
|
CN110997691B
(zh)
|
2017-07-28 |
2023-11-07 |
百时美施贵宝公司 |
作为抗癌剂的环二核苷酸
|
JOP20200016B1
(ar)
*
|
2017-08-01 |
2022-10-30 |
Lilly Co Eli |
أجسام مضادة لـ cd137
|
JP7269917B2
(ja)
|
2017-08-17 |
2023-05-09 |
イケナ オンコロジー, インコーポレイテッド |
Ahr阻害剤およびその使用
|
WO2019036855A1
(en)
|
2017-08-21 |
2019-02-28 |
Adagene Inc. |
ANTI-CD137 MOLECULES AND THEIR USE
|
ES2904317T3
(es)
|
2017-08-31 |
2022-04-04 |
Bristol Myers Squibb Co |
Dinucleótidos cíclicos como agentes anticancerosos
|
CN111032672A
(zh)
|
2017-08-31 |
2020-04-17 |
百时美施贵宝公司 |
作为抗癌剂的环二核苷酸
|
JP7209697B2
(ja)
|
2017-08-31 |
2023-01-20 |
ブリストル-マイヤーズ スクイブ カンパニー |
抗癌剤としての環状ジヌクレオチド
|
EP3684366A4
(en)
|
2017-09-22 |
2021-09-08 |
Kymera Therapeutics, Inc. |
CRBN LIGANDS AND USES OF THE LATEST
|
IL307995A
(en)
|
2017-09-22 |
2023-12-01 |
Kymera Therapeutics Inc |
Protein compounds and their uses
|
WO2019074822A1
(en)
|
2017-10-09 |
2019-04-18 |
Bristol-Myers Squibb Company |
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND METHODS OF USE
|
US11203592B2
(en)
|
2017-10-09 |
2021-12-21 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
US20230192897A1
(en)
|
2017-10-10 |
2023-06-22 |
Numab Therapeutics AG |
Multispecific antibody
|
EP3470428A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Innovation AG |
Antibodies targeting cd137 and methods of use thereof
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
MA50354A
(fr)
*
|
2017-10-10 |
2020-08-19 |
Numab Therapeutics AG |
Anticorps ciblant le cd137 et leurs méthodes d'utilisation
|
CN111344297B
(zh)
|
2017-10-10 |
2023-10-20 |
百时美施贵宝公司 |
作为抗癌剂的环二核苷酸
|
CN109651507B
(zh)
*
|
2017-10-12 |
2021-11-26 |
瑞阳(苏州)生物科技有限公司 |
一种激动型4-1bb单克隆抗体
|
WO2019079261A1
(en)
|
2017-10-16 |
2019-04-25 |
Bristol-Myers Squibb Company |
CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
EP3704159A1
(en)
|
2017-11-01 |
2020-09-09 |
Bristol-Myers Squibb Company |
Immunostimulatory agonistic antibodies for use in treating cancer
|
US11166959B2
(en)
|
2017-11-06 |
2021-11-09 |
Bristol-Myers Squibb Company |
Isofuranone compounds useful as HPK1 inhibitors
|
CA3081539A1
(en)
|
2017-11-08 |
2019-05-16 |
Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. |
Conjugates of biomolecule and use thereof
|
TWI701259B
(zh)
*
|
2017-11-09 |
2020-08-11 |
大陸商上海懷越生物科技有限公司 |
4﹘1bb抗體及其製備方法和應用
|
KR20200100060A
(ko)
|
2017-11-17 |
2020-08-25 |
이오반스 바이오테라퓨틱스, 인크. |
미세 바늘 흡인물 및 소형 생검물로부터의 til 확장
|
EP3713961A2
(en)
|
2017-11-20 |
2020-09-30 |
Compass Therapeutics LLC |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
WO2019109238A1
(en)
|
2017-12-05 |
2019-06-13 |
Lyvgen Biopharma Co., Ltd. |
Anti-cd137 antibodies and uses thereof
|
IL304055A
(en)
|
2017-12-26 |
2023-08-01 |
Kymera Therapeutics Inc |
IRAK joints and used in them
|
CN110003332B
(zh)
*
|
2018-01-05 |
2021-05-11 |
上海原能细胞医学技术有限公司 |
Cd137抗体及其应用
|
US11447449B2
(en)
|
2018-01-05 |
2022-09-20 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
WO2019136459A1
(en)
|
2018-01-08 |
2019-07-11 |
Iovance Biotherapeutics, Inc. |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
BR112020013848A2
(pt)
|
2018-01-08 |
2020-12-01 |
Iovance Biotherapeutics, Inc. |
métodos para expandir linfócitos infiltrantes de tumor e para tratar um indivíduo com câncer, população de linfócitos infiltrantes de tumor, e, método para avaliar fatores de transcrição
|
US11713446B2
(en)
|
2018-01-08 |
2023-08-01 |
Iovance Biotherapeutics, Inc. |
Processes for generating TIL products enriched for tumor antigen-specific T-cells
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
CN111886255A
(zh)
|
2018-01-12 |
2020-11-03 |
百时美施贵宝公司 |
抗tim3抗体及其用途
|
WO2019140380A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
MX2020007543A
(es)
*
|
2018-01-15 |
2020-09-09 |
Pfizer |
Metodos para administrar inmunoterapia de receptor de antigeno quimerico en combinacion con agonista 4-1bb.
|
TW201932491A
(zh)
*
|
2018-01-22 |
2019-08-16 |
大陸商江蘇恆瑞醫藥股份有限公司 |
抗4-1bb抗體、其抗原結合片段及其醫藥用途
|
CN118005640A
(zh)
|
2018-01-29 |
2024-05-10 |
默克专利股份有限公司 |
Gcn2抑制剂及其用途
|
CN111867581B
(zh)
|
2018-01-29 |
2023-12-26 |
默克专利股份有限公司 |
Gcn2抑制剂及其用途
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
US10519187B2
(en)
|
2018-02-13 |
2019-12-31 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
MA51875A
(fr)
|
2018-02-13 |
2020-12-23 |
Iovance Biotherapeutics Inc |
Expansion de lymphocytes infiltrant les tumeurs (til) avec des antagonistes du récepteur a2a de l'adénosine et combinaisons thérapeutiques de til et d'antagonistes du récepteur a2a de l'adénosine
|
WO2019165315A1
(en)
|
2018-02-23 |
2019-08-29 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists alone or in combination
|
WO2019173798A1
(en)
|
2018-03-08 |
2019-09-12 |
Rubius Therapeutics, Inc. |
Therapeutic cell systems and methods for treating cancer and infectious diseases
|
CN111801341B
(zh)
|
2018-03-08 |
2023-10-24 |
百时美施贵宝公司 |
作为抗癌剂的环二核苷酸
|
CN111971304A
(zh)
|
2018-03-21 |
2020-11-20 |
戊瑞治疗有限公司 |
在酸性pH结合至VISTA的抗体
|
MA52076A
(fr)
*
|
2018-03-23 |
2021-01-27 |
Lilly Co Eli |
Anticorps anti-cd137 pour une combinaison avec des anticorps anti-pd-1
|
CA3094763C
(en)
*
|
2018-03-23 |
2024-01-02 |
Eli Lilly And Company |
Anti-cd137 antibodies for combination with anti-pd-l1 antibodies
|
CN112513254A
(zh)
|
2018-03-29 |
2021-03-16 |
艾欧凡斯生物治疗公司 |
肿瘤浸润淋巴细胞的制备方法及其在免疫治疗中的用途
|
EP3773720A4
(en)
*
|
2018-04-10 |
2022-01-05 |
Wuxi Biologics (Shanghai) Co. Ltd. |
MONOCLONAL ANTIBODY AGAINST HUMAN 4-1BB, ITS PREPARATION PROCESS, AND ITS USE
|
KR20200142542A
(ko)
|
2018-04-12 |
2020-12-22 |
브리스톨-마이어스 스큅 컴퍼니 |
Cd73 길항제 항체 및 pd-1/pd-l1 축 길항제 항체에 의한 항암 조합 요법
|
BR112020016997A2
(pt)
|
2018-04-13 |
2021-01-19 |
F. Hoffmann-La Roche Ag |
Moléculas de ligação e de ácido nucleico isolada, vetor, célula hospedeira, métodos para produzir a molécula de ligação, para tratar um indivíduo com câncer e para regular positivamente ou prolongar a atividade de células t, composição farmacêutica e uso da molécula de ligação
|
AU2019255196A1
(en)
|
2018-04-16 |
2020-11-12 |
Arrys Therapeutics, Inc. |
EP4 inhibitors and use thereof
|
MX2020011134A
(es)
|
2018-04-27 |
2020-11-11 |
Iovance Biotherapeutics Inc |
Proceso cerrado para expansion y edicion de genes de linfocitos infiltrantes de tumor y usos de los mismos en inmunoterapia.
|
US20230339891A1
(en)
|
2018-05-03 |
2023-10-26 |
Bristol-Myers Squibb Company |
Uracil derivatives as mer-axl inhibitors
|
WO2019217753A1
(en)
|
2018-05-10 |
2019-11-14 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
CA3103629A1
(en)
|
2018-06-15 |
2019-12-19 |
Flagship Pioneering Innovations V, Inc. |
Increasing immune activity through modulation of postcellular signaling factors
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
WO2020006018A1
(en)
|
2018-06-27 |
2020-01-02 |
Bristol-Myers Squibb Company |
Substituted naphthyridinone compounds useful as t cell activators
|
SG11202012973RA
(en)
|
2018-06-27 |
2021-01-28 |
Bristol Myers Squibb Co |
Naphthyridinone compounds useful as t cell activators
|
WO2020010177A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Tricyclic crbn ligands and uses thereof
|
MX2021000009A
(es)
|
2018-07-09 |
2021-03-09 |
Five Prime Therapeutics Inc |
Anticuerpos de union a transcripcion tipo inmunoglobulina 4 (ilt4).
|
PE20210687A1
(es)
|
2018-07-11 |
2021-04-08 |
Bristol Myers Squibb Co |
Anticuerpos de union a vista a ph acido
|
US20220048996A1
(en)
|
2018-07-12 |
2022-02-17 |
F-Star Beta Limited |
Antibody molecules that bind cd137 and ox40
|
GB201811404D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-CD137 Antibodies
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
EP3820569A1
(en)
|
2018-07-12 |
2021-05-19 |
F-Star Beta Limited |
Antibody molecules that bind pd-l1 and cd137
|
CN112334488B
(zh)
|
2018-07-19 |
2023-12-08 |
伊莱利利公司 |
靶向免疫检查点的双特异性抗体
|
WO2020023355A1
(en)
|
2018-07-23 |
2020-01-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
US20210355113A1
(en)
|
2018-07-23 |
2021-11-18 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
CA3107079A1
(en)
|
2018-07-27 |
2020-01-30 |
Arcus Biosciences, Inc. |
Pyridone a2r antagonists
|
KR102259473B1
(ko)
|
2018-08-10 |
2021-06-02 |
추가이 세이야쿠 가부시키가이샤 |
항cd137 항원 결합 분자 및 그의 사용
|
US10959986B2
(en)
|
2018-08-29 |
2021-03-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
US11253525B2
(en)
|
2018-08-29 |
2022-02-22 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療
|
CN113164419A
(zh)
|
2018-09-07 |
2021-07-23 |
皮克医疗公司 |
Eif4e抑制剂和其用途
|
WO2020061429A1
(en)
|
2018-09-20 |
2020-03-26 |
Iovance Biotherapeutics, Inc. |
Expansion of tils from cryopreserved tumor samples
|
EP3636320A1
(en)
|
2018-10-09 |
2020-04-15 |
Numab Therapeutics AG |
Antibodies targeting cd137 and methods of use thereof
|
CN112805068A
(zh)
|
2018-10-09 |
2021-05-14 |
努玛治疗有限公司 |
靶向cd137的抗体及其使用方法
|
EP3863722A2
(en)
|
2018-10-10 |
2021-08-18 |
Tilos Theapeutics, Inc. |
Anti-lap antibody variants and uses thereof
|
EP3864049A1
(en)
|
2018-10-11 |
2021-08-18 |
Inhibrx, Inc. |
Pd-1 single domain antibodies and therapeutic compositions thereof
|
PE20211292A1
(es)
|
2018-11-05 |
2021-07-20 |
Iovance Biotherapeutics Inc |
Procesos para la produccion de linfocitos infiltrantes de tumor y usos de estos en inmunoterapia
|
JP2022512899A
(ja)
|
2018-11-05 |
2022-02-07 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
抗pd-1抗体に対して不応性のnsclc患者の治療
|
US20220033775A1
(en)
|
2018-11-05 |
2022-02-03 |
Iovance Biotherapeutics, Inc. |
Expansion of tils utilizing akt pathways inhibitors
|
EP3877512A2
(en)
|
2018-11-05 |
2021-09-15 |
Iovance Biotherapeutics, Inc. |
Selection of improved tumor reactive t-cells
|
MX2021006379A
(es)
*
|
2018-11-30 |
2021-10-13 |
Abl Bio Inc |
Anticuerpos biespecificos anti-pd-l1/anti-4-1bb y usos de los mismos.
|
JP2022516401A
(ja)
|
2018-11-30 |
2022-02-28 |
カイメラ セラピューティクス, インコーポレイテッド |
Irak分解剤およびそれらの使用
|
WO2020131547A1
(en)
|
2018-12-19 |
2020-06-25 |
Iovance Biotherapeutics, Inc. |
Methods of expanding tumor infiltrating lymphocytes using engineered cytokine receptor pairs and uses thereof
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
US20220153864A1
(en)
|
2019-02-26 |
2022-05-19 |
Pieris Pharmaceuticals Gmbh |
Novel Fusion Proteins Specific for CD137 and GPC3
|
WO2020187998A1
(en)
|
2019-03-19 |
2020-09-24 |
Fundació Privada Institut D'investigació Oncològica De Vall Hebron |
Combination therapy with omomyc and an antibody binding pd-1 or ctla-4 for the treatment of cancer
|
CA3134144A1
(en)
|
2019-03-29 |
2020-10-08 |
Myst Therapeutics, Llc |
Ex vivo methods for producing a t cell therapeutic and related compositions and methods
|
JP2022528887A
(ja)
|
2019-04-02 |
2022-06-16 |
バイスクルテクス・リミテッド |
バイシクルトキシンコンジュゲートおよびその使用
|
US11485750B1
(en)
|
2019-04-05 |
2022-11-01 |
Kymera Therapeutics, Inc. |
STAT degraders and uses thereof
|
EP3958908A1
(en)
|
2019-04-24 |
2022-03-02 |
Heidelberg Pharma Research GmbH |
Amatoxin antibody-drug conjugates and uses thereof
|
WO2020227159A2
(en)
|
2019-05-03 |
2020-11-12 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity
|
KR20220008306A
(ko)
|
2019-05-10 |
2022-01-20 |
리브젠 바이오파마 코., 엘티디. |
인간화 항-cd137 항체 및 이의 용도
|
WO2020231713A1
(en)
|
2019-05-13 |
2020-11-19 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
WO2020231766A1
(en)
|
2019-05-13 |
2020-11-19 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
US20220249559A1
(en)
|
2019-05-13 |
2022-08-11 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for selecting tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
CA3141452A1
(en)
|
2019-05-24 |
2020-12-03 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
JP2022534889A
(ja)
|
2019-05-24 |
2022-08-04 |
ファイザー・インコーポレイテッド |
Cdk阻害剤を使用した組合せ療法
|
TW202108559A
(zh)
|
2019-05-31 |
2021-03-01 |
美商醫肯納腫瘤學公司 |
Tead抑制劑及其用途
|
KR20220016945A
(ko)
|
2019-06-04 |
2022-02-10 |
몰리큘라 파트너스 아게 |
다중특이적 단백질
|
US20220306630A1
(en)
|
2019-08-06 |
2022-09-29 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
AR119821A1
(es)
|
2019-08-28 |
2022-01-12 |
Bristol Myers Squibb Co |
Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
|
WO2021050964A1
(en)
|
2019-09-13 |
2021-03-18 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
JP2022548292A
(ja)
|
2019-09-19 |
2022-11-17 |
ブリストル-マイヤーズ スクイブ カンパニー |
酸性pHでVISTAと結合する抗体
|
MX2022003633A
(es)
|
2019-09-25 |
2022-04-19 |
Pfizer |
Moduladores poliheterociclicos de sting (estimulador de genes de interferon).
|
US20220389381A1
(en)
|
2019-10-25 |
2022-12-08 |
Iovance Biotherapeutics, Inc. |
Gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
JP7432716B2
(ja)
|
2019-11-13 |
2024-02-16 |
合肥瀚科邁博生物技術有限公司 |
ヒト4-1bbに結合可能な分子及びその応用
|
CN112898426A
(zh)
*
|
2019-11-19 |
2021-06-04 |
非同(成都)生物科技有限公司 |
人源化4-1bb单克隆抗体及其药物组合物
|
MX2022005839A
(es)
|
2019-11-19 |
2022-06-09 |
Bristol Myers Squibb Co |
Compuestos utiles como inhibidores de la proteina helios.
|
JP2023502531A
(ja)
|
2019-11-26 |
2023-01-24 |
イケナ オンコロジー, インコーポレイテッド |
多形カルバゾール誘導体およびその使用
|
IL293357A
(en)
|
2019-11-26 |
2022-07-01 |
Bristol Myers Squibb Co |
Salts/crystals of (r)-n-(4-chlorophenyl)-2-((1s,4s)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
|
IL293350A
(en)
|
2019-11-27 |
2022-07-01 |
Myst Therapeutics Llc |
A method for producing tumor-reactive t cells using modulatory substances
|
CA3161104A1
(en)
|
2019-12-11 |
2021-06-17 |
Cecile Chartier-Courtaud |
Processes for the production of tumor infiltrating lymphocytes (tils) and methods of using the same
|
MX2022007576A
(es)
|
2019-12-17 |
2022-09-23 |
Kymera Therapeutics Inc |
Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
|
WO2021127217A1
(en)
|
2019-12-17 |
2021-06-24 |
Flagship Pioneering Innovations V, Inc. |
Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly
|
EP4076524A4
(en)
|
2019-12-17 |
2023-11-29 |
Kymera Therapeutics, Inc. |
IRAQ DEGRADERS AND USES THEREOF
|
BR112022009470A2
(pt)
|
2019-12-18 |
2022-08-16 |
Pfizer |
Regime de tratamento diário para o câncer com um inibidor de prmt5
|
US20230094758A1
(en)
|
2019-12-23 |
2023-03-30 |
Bristol-Myers Squibb Company |
Substituted quinazolinyl compounds useful as t cell activators
|
AR120823A1
(es)
|
2019-12-23 |
2022-03-23 |
Bristol Myers Squibb Co |
Compuestos bicíclicos sustituidos útiles como activadores de células t
|
CA3162979A1
(en)
|
2019-12-23 |
2021-07-01 |
Upender Velaparthi |
Substituted piperazine derivatives useful as t cell activators
|
CN114846015A
(zh)
|
2019-12-23 |
2022-08-02 |
百时美施贵宝公司 |
用作t细胞激活剂的经取代的杂芳基化合物
|
CN115297931A
(zh)
|
2019-12-23 |
2022-11-04 |
凯麦拉医疗公司 |
Smarca降解剂和其用途
|
IL294269A
(en)
|
2019-12-23 |
2022-08-01 |
Bristol Myers Squibb Co |
Substitute quinolinyl piperazine compounds are useful as t-cell activators
|
AU2021206618A1
(en)
|
2020-01-06 |
2022-08-18 |
Hifibio, Inc. |
Anti-TNFR2 antibody and uses thereof
|
WO2021141977A1
(en)
|
2020-01-07 |
2021-07-15 |
Board Of Regents, The University Of Texas System |
Improved human methyl thioadenosine/adenosine depleting enzyme variants for cancer therapy
|
BR112022013494A2
(pt)
|
2020-01-07 |
2022-09-13 |
Hifibio Hk Ltd |
Anticorpo anti-galectina-9 e usos do mesmo
|
EP4090663A1
(en)
|
2020-01-15 |
2022-11-23 |
Blueprint Medicines Corporation |
Map4k1 inhibitors
|
TW202144395A
(zh)
*
|
2020-02-12 |
2021-12-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
US20230106973A1
(en)
|
2020-02-17 |
2023-04-06 |
Board Of Regents, The University Of Texas System |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
CN115427438A
(zh)
|
2020-02-27 |
2022-12-02 |
迈斯特治疗公司 |
肿瘤反应性t细胞的离体富集和扩增的方法及其相关组合物
|
BR112022016491A2
(pt)
*
|
2020-02-28 |
2022-10-11 |
Shanghai Henlius Biotech Inc |
Construto anti-cd137 e usos do mesmo
|
CN115151573A
(zh)
|
2020-02-28 |
2022-10-04 |
上海复宏汉霖生物技术股份有限公司 |
抗cd137构建体、多特异性抗体及其用途
|
BR112022017727A2
(pt)
|
2020-03-03 |
2022-11-16 |
Pic Therapeutics Inc |
Inibidores de eif4e e usos dos mesmos
|
JP2023517044A
(ja)
|
2020-03-09 |
2023-04-21 |
ファイザー・インク |
融合タンパク質およびその使用
|
TW202200543A
(zh)
|
2020-03-19 |
2022-01-01 |
美商凱麥拉醫療公司 |
Mdm2降解劑及其用途
|
BR112022018600A2
(pt)
|
2020-03-19 |
2022-11-08 |
Arcus Biosciences Inc |
Compostos, composição farmacêutica, método de tratamento de uma doença e combinação
|
TW202140441A
(zh)
|
2020-03-23 |
2021-11-01 |
美商必治妥美雅史谷比公司 |
經取代之側氧基異吲哚啉化合物
|
US20230272056A1
(en)
|
2020-04-09 |
2023-08-31 |
Merck Sharp & Dohme Llc |
Affinity matured anti-lap antibodies and uses thereof
|
CA3177413A1
(en)
|
2020-05-04 |
2021-11-11 |
Michelle SIMPSON-ABELSON |
Selection of improved tumor reactive t-cells
|
US20230172987A1
(en)
|
2020-05-04 |
2023-06-08 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
BR112022021956A2
(pt)
|
2020-05-13 |
2022-12-13 |
Pfizer |
Métodos, terapias e usos para o tratamento de câncer
|
CA3176246A1
(en)
|
2020-06-02 |
2021-12-09 |
Arcus Biosciences, Inc. |
Antibodies to tigit
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
WO2021258010A1
(en)
|
2020-06-19 |
2021-12-23 |
Gossamer Bio Services, Inc. |
Oxime compounds useful as t cell activators
|
JP2023532339A
(ja)
|
2020-06-29 |
2023-07-27 |
フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド |
サノトランスミッションを促進するためにエンジニアリングされたウイルス及び癌の処置におけるそれらの使用
|
CA3187255A1
(en)
|
2020-07-30 |
2022-02-03 |
Duncan Walker |
Methods of treating mutant lymphomas
|
WO2022033419A2
(en)
|
2020-08-10 |
2022-02-17 |
Shanghai Xbh Biotechnology Co., Ltd. |
Compositions and methods for treating autoimmune diseases and cancers by targeting igsf8
|
MX2023001588A
(es)
|
2020-08-17 |
2023-05-03 |
Bicycletx Ltd |
Conjugados biciclo específicos para nectina-4 y usos de estos.
|
CN116194105A
(zh)
|
2020-09-14 |
2023-05-30 |
辉瑞大药厂 |
治疗癌症的方法、疗法及用途
|
CN114195894A
(zh)
*
|
2020-09-17 |
2022-03-18 |
普米斯生物技术(珠海)有限公司 |
一种靶向4-1bb的抗体及其应用
|
CN114195900B
(zh)
|
2020-09-17 |
2024-02-23 |
普米斯生物技术(珠海)有限公司 |
一种抗4-1bb/pd-l1双特异性抗体及其用途
|
WO2022076606A1
(en)
|
2020-10-06 |
2022-04-14 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
EP4225330A1
(en)
|
2020-10-06 |
2023-08-16 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
US20230416382A1
(en)
|
2020-10-14 |
2023-12-28 |
Five Prime Therapeutics, Inc. |
Anti-c-c chemokine receptor 8 (ccr8) antibodies and methods of use thereof
|
EP3988568A1
(en)
|
2020-10-21 |
2022-04-27 |
Numab Therapeutics AG |
Combination treatment
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
CA3200814A1
(en)
|
2020-12-02 |
2022-06-09 |
Alfredo C. Castro |
Tead inhibitors and uses thereof
|
WO2022125941A1
(en)
|
2020-12-11 |
2022-06-16 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with braf inhibitors and/or mek inhibitors
|
AU2021400725A1
(en)
|
2020-12-16 |
2023-08-03 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
JP2023554395A
(ja)
|
2020-12-17 |
2023-12-27 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Ctla-4及びpd-1阻害剤と併用した腫瘍浸潤リンパ球療法による治療
|
CA3202473A1
(en)
|
2020-12-17 |
2022-06-23 |
Friedrich Graf Finckenstein |
Treatment of cancers with tumor infiltrating lymphocytes
|
WO2022148979A1
(en)
|
2021-01-11 |
2022-07-14 |
Bicycletx Limited |
Methods for treating cancer
|
WO2022153161A1
(en)
|
2021-01-14 |
2022-07-21 |
Pfizer Inc. |
Treatment of cancer using a prmt5 inhibitor
|
EP4288430A1
(en)
|
2021-02-02 |
2023-12-13 |
Liminal Biosciences Limited |
Gpr84 antagonists and uses thereof
|
JP2024505571A
(ja)
|
2021-02-02 |
2024-02-06 |
リミナル・バイオサイエンシーズ・リミテッド |
Gpr84アンタゴニストおよびその使用
|
US20240109899A1
(en)
|
2021-02-04 |
2024-04-04 |
Bristol-Myers Squibb Company |
Benzofuran compounds as sting agonists
|
WO2022170219A1
(en)
|
2021-02-05 |
2022-08-11 |
Iovance Biotherapeutics, Inc. |
Adjuvant therapy for cancer
|
AU2022221124A1
(en)
|
2021-02-12 |
2023-08-03 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives for the treatment of cancer
|
WO2022174269A1
(en)
|
2021-02-15 |
2022-08-18 |
Kymera Therapeutics, Inc. |
Irak4 degraders and uses thereof
|
WO2022187741A2
(en)
|
2021-03-05 |
2022-09-09 |
Iovance Biotherapeutics, Inc. |
Tumor storage and cell culture compositions
|
EP4301756A1
(en)
|
2021-03-05 |
2024-01-10 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
WO2022192145A1
(en)
|
2021-03-08 |
2022-09-15 |
Blueprint Medicines Corporation |
Map4k1 inhibitors
|
US11918582B2
(en)
|
2021-03-15 |
2024-03-05 |
Rapt Therapeutics, Inc. |
Pyrazole pyrimidine compounds and uses thereof
|
US11964978B2
(en)
|
2021-03-18 |
2024-04-23 |
Pfizer Inc. |
Modulators of STING (stimulator of interferon genes)
|
EP4313109A1
(en)
|
2021-03-31 |
2024-02-07 |
Flagship Pioneering Innovations V, Inc. |
Thanotransmission polypeptides and their use in treating cancer
|
AU2022253450A1
(en)
|
2021-04-05 |
2023-11-16 |
Bristol-Myers Squibb Company |
Pyridinyl substituted oxoisoindoline compounds for the treatment of cancer
|
WO2022216644A1
(en)
|
2021-04-06 |
2022-10-13 |
Bristol-Myers Squibb Company |
Pyridinyl substituted oxoisoindoline compounds
|
IL307673A
(en)
|
2021-04-16 |
2023-12-01 |
Ikena Oncology Inc |
MEK inhibitors and their use
|
WO2022225981A2
(en)
|
2021-04-19 |
2022-10-27 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
EP4340850A1
(en)
|
2021-05-17 |
2024-03-27 |
Iovance Biotherapeutics, Inc. |
Pd-1 gene-edited tumor infiltrating lymphocytes and uses of same in immunotherapy
|
WO2022246177A1
(en)
|
2021-05-21 |
2022-11-24 |
Arcus Biosciences, Inc. |
Axl compounds
|
TW202313603A
(zh)
|
2021-05-21 |
2023-04-01 |
美商阿克思生物科學有限公司 |
Axl抑制劑化合物
|
WO2022261018A1
(en)
|
2021-06-07 |
2022-12-15 |
Providence Health & Services - Oregon |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
CA3224374A1
(en)
|
2021-06-29 |
2023-01-05 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
EP4370523A1
(en)
|
2021-07-14 |
2024-05-22 |
Blueprint Medicines Corporation |
Heterocyclic compounds as map4k1 inhibitors
|
CN117940406A
(zh)
|
2021-07-15 |
2024-04-26 |
缆图药品公司 |
Map4k1抑制剂
|
TW202327631A
(zh)
|
2021-07-28 |
2023-07-16 |
美商艾歐凡斯生物治療公司 |
利用腫瘤浸潤性淋巴球療法與kras抑制劑組合治療癌症患者
|
US20230134932A1
(en)
|
2021-08-25 |
2023-05-04 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
US20230150997A1
(en)
|
2021-08-25 |
2023-05-18 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
WO2023049862A1
(en)
|
2021-09-24 |
2023-03-30 |
Iovance Biotherapeutics, Inc. |
Expansion processes and agents for tumor infiltrating lymphocytes
|
CA3233994A1
(en)
*
|
2021-10-12 |
2023-04-20 |
Wenci GONG |
Single-domain 4-1bb antibodies
|
WO2023064958A1
(en)
|
2021-10-15 |
2023-04-20 |
Compugen Ltd. |
Combination therapy with anti-pvrig antibodies formulations, anti-tigit antibodies, and anti-pd-1 antibodies
|
TW202331735A
(zh)
|
2021-10-27 |
2023-08-01 |
美商艾歐凡斯生物治療公司 |
協調用於患者特異性免疫療法之細胞之製造的系統及方法
|
TW202325279A
(zh)
|
2021-10-29 |
2023-07-01 |
美商阿克思生物科學有限公司 |
HIF-2α抑制劑及其使用方法
|
AU2022388729A1
(en)
|
2021-11-10 |
2024-05-16 |
Iovance Biotherapeutics, Inc. |
Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
WO2023122777A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
WO2023122772A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
WO2023122778A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Pyridazinone derivatives useful as t cell activators
|
WO2023147486A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Tumor infiltrating lymphocytes engineered to express payloads
|
WO2023150186A1
(en)
|
2022-02-01 |
2023-08-10 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023201369A1
(en)
|
2022-04-15 |
2023-10-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
WO2023215719A1
(en)
|
2022-05-02 |
2023-11-09 |
Arcus Biosciences, Inc. |
Anti-tigit antibodies and uses of the same
|
WO2023230205A1
(en)
|
2022-05-25 |
2023-11-30 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2024015251A1
(en)
|
2022-07-15 |
2024-01-18 |
Arcus Biosciences, Inc. |
Inhibitors of hpk1 and methods of use thereof
|
WO2024020034A1
(en)
|
2022-07-20 |
2024-01-25 |
Arcus Biosciences, Inc. |
Cbl-b inhibitors and methods of use thereof
|
WO2024030758A1
(en)
|
2022-08-01 |
2024-02-08 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
WO2024028364A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Aryl-triazolyl and related gpr84 antagonists and uses thereof
|
WO2024028363A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Heteroaryl carboxamide and related gpr84 antagonists and uses thereof
|
WO2024028365A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Substituted pyridone gpr84 antagonists and uses thereof
|
WO2024036100A1
(en)
|
2022-08-08 |
2024-02-15 |
Bristol-Myers Squibb Company |
Substituted tetrazolyl compounds useful as t cell activators
|
WO2024036101A1
(en)
|
2022-08-09 |
2024-02-15 |
Bristol-Myers Squibb Company |
Tertiary amine substituted bicyclic compounds useful as t cell activators
|
WO2024033388A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024033389A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024033457A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024033458A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives
|
WO2024040194A1
(en)
|
2022-08-17 |
2024-02-22 |
Capstan Therapeutics, Inc. |
Conditioning for in vivo immune cell engineering
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
WO2024081385A1
(en)
|
2022-10-14 |
2024-04-18 |
Arcus Biosciences, Inc. |
Hpk1 inhibitors and methods of use thereof
|
WO2024086718A1
(en)
|
2022-10-20 |
2024-04-25 |
Arcus Biosciences, Inc. |
Lyophilized formulations of cd73 compounds
|