CO5601011A2 - Derivados de 3-ciclil-5-(anillo de 5 miembros que contiene nitrogeno) metil-oxazolidinona y su uso como agentes antibacterianos - Google Patents

Derivados de 3-ciclil-5-(anillo de 5 miembros que contiene nitrogeno) metil-oxazolidinona y su uso como agentes antibacterianos

Info

Publication number
CO5601011A2
CO5601011A2 CO04083221A CO04083221A CO5601011A2 CO 5601011 A2 CO5601011 A2 CO 5601011A2 CO 04083221 A CO04083221 A CO 04083221A CO 04083221 A CO04083221 A CO 04083221A CO 5601011 A2 CO5601011 A2 CO 5601011A2
Authority
CO
Colombia
Prior art keywords
ciclil
oxazolidinone
derivatives
methyl
ring
Prior art date
Application number
CO04083221A
Other languages
English (en)
Inventor
Michael Barry Gravestock
Neil James Hales
Folkert Reeck
Yuefen Zhou
Paul Robert Fleming
Daniel Robert Carcanague
Marc Michel Girardot
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CO5601011A2 publication Critical patent/CO5601011A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1.- Un compuesto de fórmula (I), ó una sal farmacéuticamente aceptable, ó un éster hidrolizable in vivo de éste, en donde -N-HET se selecciona de las estructuras (la) a (If) siguientes:en donde u y v son independientemente 0 ó 1;R1 es un grupo alquil C1-C4;Q se selecciona de Q1 a Q6:en donde R2 y R3 son independientemente seleccionados entre H, F, Cl, CF3, OMe, SMe, Me y Et, en donde B1 es O ó S;en donde T se selecciona de los grupos de (TA) hasta (TE) siguientes (en donde AR1, AR2, AR2a, AR2b, AR3, AR3a, AR3b, AR4, AR4a, CY1 y CY2 se definen más adelante); ...
CO04083221A 2002-02-28 2004-08-25 Derivados de 3-ciclil-5-(anillo de 5 miembros que contiene nitrogeno) metil-oxazolidinona y su uso como agentes antibacterianos CO5601011A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36095702P 2002-02-28 2002-02-28

Publications (1)

Publication Number Publication Date
CO5601011A2 true CO5601011A2 (es) 2006-01-31

Family

ID=27766248

Family Applications (1)

Application Number Title Priority Date Filing Date
CO04083221A CO5601011A2 (es) 2002-02-28 2004-08-25 Derivados de 3-ciclil-5-(anillo de 5 miembros que contiene nitrogeno) metil-oxazolidinona y su uso como agentes antibacterianos

Country Status (20)

Country Link
US (1) US7473699B2 (es)
EP (1) EP1497286A1 (es)
JP (1) JP2005524661A (es)
KR (1) KR20040087329A (es)
CN (1) CN1649866A (es)
AR (1) AR040399A1 (es)
AU (1) AU2003207340A1 (es)
BR (1) BR0308056A (es)
CA (1) CA2477344A1 (es)
CO (1) CO5601011A2 (es)
IL (1) IL163688A0 (es)
IS (1) IS7427A (es)
MX (1) MXPA04008312A (es)
NO (1) NO20043950L (es)
NZ (1) NZ535592A (es)
PL (1) PL372191A1 (es)
RU (1) RU2004129276A (es)
TW (1) TW200304821A (es)
WO (1) WO2003072575A1 (es)
ZA (1) ZA200406812B (es)

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Also Published As

Publication number Publication date
PL372191A1 (en) 2005-07-11
NZ535592A (en) 2006-07-28
AU2003207340A1 (en) 2003-09-09
RU2004129276A (ru) 2005-06-10
US20050119292A1 (en) 2005-06-02
BR0308056A (pt) 2004-12-07
IL163688A0 (en) 2005-12-18
EP1497286A1 (en) 2005-01-19
CN1649866A (zh) 2005-08-03
KR20040087329A (ko) 2004-10-13
US7473699B2 (en) 2009-01-06
JP2005524661A (ja) 2005-08-18
AR040399A1 (es) 2005-04-06
TW200304821A (en) 2003-10-16
MXPA04008312A (es) 2004-11-26
NO20043950L (no) 2004-10-13
CA2477344A1 (en) 2003-09-04
IS7427A (is) 2004-08-27
ZA200406812B (en) 2005-09-12
WO2003072575A1 (en) 2003-09-04

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