US4450150A
(en)
|
1973-05-17 |
1984-05-22 |
Arthur D. Little, Inc. |
Biodegradable, implantable drug delivery depots, and method for preparing and using the same
|
JPS63502716A
(ja)
|
1986-03-07 |
1988-10-13 |
マサチューセッツ・インステチュート・オブ・テクノロジー |
糖タンパク安定性の強化方法
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
WO1988009344A1
(en)
|
1987-05-21 |
1988-12-01 |
Creative Biomolecules, Inc. |
Targeted multifunctional proteins
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
DK0710719T3
(da)
|
1990-01-12 |
2007-07-09 |
Amgen Fremont Inc |
Frembringelse af xenogene antistoffer
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
EP0814159B1
(en)
|
1990-08-29 |
2005-07-27 |
GenPharm International, Inc. |
Transgenic mice capable of producing heterologous antibodies
|
US6770274B1
(en)
|
1990-09-14 |
2004-08-03 |
The General Hospital Corporation |
Viral mutant HSV mediated destruction of neoplastic cells
|
DK0564531T3
(da)
|
1990-12-03 |
1998-09-28 |
Genentech Inc |
Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber
|
US5780279A
(en)
|
1990-12-03 |
1998-07-14 |
Genentech, Inc. |
Method of selection of proteolytic cleavage sites by directed evolution and phagemid display
|
JP3266311B2
(ja)
|
1991-05-02 |
2002-03-18 |
生化学工業株式会社 |
新規ポリペプチドおよびこれを用いる抗hiv剤
|
US5871907A
(en)
|
1991-05-15 |
1999-02-16 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US5858657A
(en)
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US6225447B1
(en)
|
1991-05-15 |
2001-05-01 |
Cambridge Antibody Technology Ltd. |
Methods for producing members of specific binding pairs
|
GB9206422D0
(en)
|
1992-03-24 |
1992-05-06 |
Bolt Sarah L |
Antibody preparation
|
US7381803B1
(en)
|
1992-03-27 |
2008-06-03 |
Pdl Biopharma, Inc. |
Humanized antibodies against CD3
|
US5855885A
(en)
|
1993-01-22 |
1999-01-05 |
Smith; Rodger |
Isolation and production of catalytic antibodies using phage technology
|
US5728379A
(en)
|
1994-06-23 |
1998-03-17 |
Georgetown University |
Tumor- or cell-specific herpes simplex virus replication
|
US6699468B1
(en)
|
1994-06-23 |
2004-03-02 |
Georgetown University |
Replication-competent herpes simplex virus mediates destruction of neoplastic cells
|
US5585096A
(en)
|
1994-06-23 |
1996-12-17 |
Georgetown University |
Replication-competent herpes simplex virus mediates destruction of neoplastic cells
|
US5702892A
(en)
|
1995-05-09 |
1997-12-30 |
The United States Of America As Represented By The Department Of Health And Human Services |
Phage-display of immunoglobulin heavy chain libraries
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
US5824318A
(en)
|
1996-07-24 |
1998-10-20 |
American Cyanamid Company |
Avirulent herpetic viruses useful as tumoricidal agents and vaccines
|
EP0942968B1
(en)
|
1996-12-03 |
2008-02-27 |
Amgen Fremont Inc. |
Fully human antibodies that bind EGFR
|
US6057098A
(en)
|
1997-04-04 |
2000-05-02 |
Biosite Diagnostics, Inc. |
Polyvalent display libraries
|
US6379674B1
(en)
|
1997-08-12 |
2002-04-30 |
Georgetown University |
Use of herpes vectors for tumor therapy
|
WO1999040942A1
(fr)
|
1998-02-10 |
1999-08-19 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Preparations a liberation controlee
|
KR100508289B1
(ko)
|
1998-04-21 |
2005-08-17 |
마이크로메트 에이지 |
Cd19×cd3 특이 폴리펩티드 및 그의 용도
|
GB9815909D0
(en)
|
1998-07-21 |
1998-09-16 |
Btg Int Ltd |
Antibody preparation
|
GB2344287A
(en)
|
1998-12-03 |
2000-06-07 |
Ferring Bv |
Controlled release pharmaceutical formulation
|
JP2003535565A
(ja)
|
1998-12-31 |
2003-12-02 |
アーチ ディベロプメント コーポレイション |
新生物疾患の治療に有用な組換え単純ヘルペスウイルス
|
US6307024B1
(en)
|
1999-03-09 |
2001-10-23 |
Zymogenetics, Inc. |
Cytokine zalpha11 Ligand
|
AU2905199A
(en)
|
1999-03-15 |
2000-10-04 |
Trustees Of The University Of Pennsylvania, The |
Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject
|
US6764675B1
(en)
|
1999-06-08 |
2004-07-20 |
The Uab Research Foundation |
Herpes simplex virus expressing foreign genes and method for treating cancers therewith
|
US6833268B1
(en)
|
1999-06-10 |
2004-12-21 |
Abgenix, Inc. |
Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions
|
ES2254359T3
(es)
|
2000-01-21 |
2006-06-16 |
Biovex Limited |
Cepa viral para el tratamiento oncolitico de canceres.
|
JP2004511425A
(ja)
|
2000-02-08 |
2004-04-15 |
ザ ペン ステート リサーチ ファウンデーション |
免疫療法に使用されるインターロイキン13受容体サブユニットアルファー2
|
WO2002076216A1
(en)
|
2001-03-27 |
2002-10-03 |
Medigene, Inc. |
Viral vectors and their use in therapeutic methods
|
AR036993A1
(es)
*
|
2001-04-02 |
2004-10-20 |
Wyeth Corp |
Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
|
ATE444363T1
(de)
|
2001-11-05 |
2009-10-15 |
Zymogenetics Inc |
Il-21-antagonisten
|
EP1461423B1
(en)
|
2001-12-03 |
2008-05-14 |
Amgen Fremont Inc. |
Antibody categorization based on binding characteristics
|
EP2338910B1
(en)
|
2002-01-18 |
2015-07-08 |
ZymoGenetics, Inc. |
Cytokine receptor Zcytor17 multimers
|
US7736652B2
(en)
|
2002-03-21 |
2010-06-15 |
The Regents Of The University Of California |
Antibody fusion proteins: effective adjuvants of protein vaccination
|
ES2381265T3
(es)
|
2002-06-07 |
2012-05-24 |
Zymogenetics, Inc. |
Uso de IL-21 y anticuerpo monoclonal para tratar cánceres sólidos
|
US7917208B2
(en)
|
2002-10-04 |
2011-03-29 |
Microchips, Inc. |
Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
|
CN1513993A
(zh)
|
2002-12-31 |
2004-07-21 |
北京博泰迪生物工程科技开发有限公司 |
中国人基因组cDNA文库白细胞介素21的编码基因序列及其蛋白质的氨基酸序列
|
JP2008501621A
(ja)
|
2003-05-31 |
2008-01-24 |
マイクロメット アクツィエン ゲゼルシャフト |
B細胞関連疾患を処置するための二重特異性抗cd3、抗cd19抗体構築物を含む薬学的組成物
|
CA2538083A1
(en)
|
2003-09-25 |
2005-04-07 |
Zymogenetics, Inc. |
Methods of treating autoimmune diseases using il-21
|
DK1673398T3
(da)
|
2003-10-16 |
2011-04-18 |
Micromet Ag |
Multispecifikke, deimmuniserede CD3-bindere
|
BRPI0511782B8
(pt)
|
2004-06-03 |
2021-05-25 |
Novimmune Sa |
anticorpos anti-cd3, uso e método de produção dos mesmos, composição farmacêutica, molécula de ácido nucleico isolada e vetor
|
WO2006002394A2
(en)
|
2004-06-24 |
2006-01-05 |
New York University |
Avirulent oncolytic herpes simplex virus strains engineered to counter the innate host response
|
EP1861399B1
(en)
|
2005-03-14 |
2011-12-14 |
Merck Sharp & Dohme Corp. |
Cgrp receptor antagonists
|
BRPI0609079A2
(pt)
|
2005-04-18 |
2010-11-16 |
Novo Nordisk As |
peptìdeo, composição farmacêutica, método para o tratamento de cáncer, uso de um peptìdeo construto de ácido nucleico, vetor, hospedeiro, e, anticorpo
|
SI2439273T1
(sl)
*
|
2005-05-09 |
2019-05-31 |
Ono Pharmaceutical Co., Ltd. |
Človeška monoklonska protitelesa za programirano smrt 1 (PD-1) in postopki za zdravljenje raka z uporabo protiteles proti PD-1 samostojno ali v kombinaciji z ostalimi imunoterapevtiki
|
EP2567973B1
(en)
|
2005-11-28 |
2014-05-14 |
Zymogenetics, Inc. |
IL-21 antagonists
|
AU2006341398B9
(en)
|
2005-11-28 |
2012-02-02 |
Zymogenetics, Inc. |
IL-21 receptor antagonists
|
TW200745163A
(en)
|
2006-02-17 |
2007-12-16 |
Syntonix Pharmaceuticals Inc |
Peptides that block the binding of IgG to FcRn
|
CA2648484A1
(en)
|
2006-05-08 |
2007-11-15 |
Philogen Spa |
Antibody-targeted cytokines for therapy
|
US8475784B2
(en)
|
2006-10-26 |
2013-07-02 |
Novo Nordisk A/S |
IL-21 variants
|
AU2007336184A1
(en)
|
2006-12-21 |
2008-06-26 |
Novo Nordisk A/S |
Interleukin-21 variants with altered binding to the IL-21 receptor
|
CN101230335B
(zh)
|
2007-01-22 |
2010-08-11 |
北京奥源和力生物技术有限公司 |
单纯疱疹病毒和重组病毒及宿主细胞及其药物组合物
|
CN101230334B
(zh)
|
2007-01-22 |
2011-06-01 |
北京奥源和力生物技术有限公司 |
单纯疱疹病毒和重组病毒及宿主细胞及其药物组合物
|
HUE040467T2
(hu)
|
2007-04-03 |
2019-03-28 |
Amgen Res Munich Gmbh |
Keresztfaj-specifikus kötõdomén
|
WO2008119567A2
(en)
|
2007-04-03 |
2008-10-09 |
Micromet Ag |
Cross-species-specific cd3-epsilon binding domain
|
AU2008241699B2
(en)
|
2007-04-19 |
2011-02-03 |
Dong-A Pharmaceutical. Co., Ltd |
A biodegradable microsphere composition suitable for the controlled release of glucose controlling peptide and formulation thereof
|
CA2910933C
(en)
|
2007-12-07 |
2017-04-11 |
Zymogenetics, Inc. |
Anti-human il-21 monoclonal antibodies
|
EP2262837A4
(en)
*
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
PD-1 BINDING PROTEINS
|
CA2721202A1
(en)
|
2008-04-17 |
2009-10-22 |
Hilde Adi Pierrette Revets |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
JP2012510429A
(ja)
*
|
2008-08-25 |
2012-05-10 |
アンプリミューン、インコーポレーテッド |
Pd−1アンタゴニストおよびその使用方法
|
KR101820535B1
(ko)
|
2008-10-01 |
2018-01-19 |
암젠 리서치 (뮌헨) 게엠베하 |
종간특이적 psmaxcd3 이중특이적 단일쇄 항체
|
EP2406282A1
(en)
|
2009-03-11 |
2012-01-18 |
Novo Nordisk A/S |
Interleukin-21 variants having antagonistic binding to the il-21 receptor
|
CA2756244A1
(en)
|
2009-04-02 |
2010-10-07 |
Roche Glycart Ag |
Multispecific antibodies comprising full length antibodies and single chain fab fragments
|
EP2975051B1
(en)
|
2009-06-26 |
2021-04-14 |
Regeneron Pharmaceuticals, Inc. |
Readily isolated bispecific antibodies with native immunoglobulin format
|
PE20120630A1
(es)
|
2009-08-17 |
2012-05-26 |
Roche Glycart Ag |
Inmunoconjugados dirigidos
|
RU2607374C2
(ru)
|
2009-10-30 |
2017-01-10 |
Новозаймс Байофарма Дк А/С |
Варианты альбумина
|
US8993524B2
(en)
|
2010-03-05 |
2015-03-31 |
The Johns Hopkins University |
Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
|
US20130225496A1
(en)
|
2010-11-01 |
2013-08-29 |
Novozymes Biopharma Dk A/S |
Albumin Variants
|
US20120258073A1
(en)
|
2011-02-10 |
2012-10-11 |
Christian Gerdes |
Immunotherapy
|
AU2012229251A1
(en)
|
2011-03-11 |
2013-09-12 |
Amgen Inc. |
Method of correlated mutational analysis to improve therapeutic antibodies
|
EA201892619A1
(ru)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
|
CN104011072B
(zh)
|
2011-05-05 |
2018-10-12 |
阿尔布梅迪克斯医疗有限公司 |
白蛋白变体
|
US11492383B2
(en)
|
2011-06-24 |
2022-11-08 |
Stephen D. Gillies |
Light chain immunoglobulin fusion proteins and methods of use thereof
|
WO2013006795A2
(en)
|
2011-07-07 |
2013-01-10 |
Humanitas International Foundation |
Antiviral compositions and methods of their use
|
DK2753355T3
(en)
|
2011-09-08 |
2019-01-28 |
Univ New York |
ONCOLYTIC HERP SIMPLEX VIRUSES AND THERAPEUTIC APPLICATIONS THEREOF
|
CN109022465B
(zh)
|
2011-10-28 |
2022-04-29 |
特瓦制药澳大利亚私人有限公司 |
多肽构建体及其用途
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
US20140315817A1
(en)
|
2011-11-18 |
2014-10-23 |
Eleven Biotherapeutics, Inc. |
Variant serum albumin with improved half-life and other properties
|
WO2013096732A2
(en)
|
2011-12-23 |
2013-06-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of treating or preventing viral diseases by blocking interleukin-21
|
WO2013109904A1
(en)
|
2012-01-19 |
2013-07-25 |
University Of Miami |
Compositions, methods and kits for treatment of cancer and autoimmune diseases
|
CA2861592A1
(en)
|
2012-03-16 |
2013-09-19 |
Novozymes Biopharma Dk A/S |
Albumin variants
|
PT3489254T
(pt)
|
2012-04-30 |
2022-12-30 |
Biocon Ltd |
Proteínas de fusão direcionadas/imunomoduladoras e seus métodos de fabrico
|
EP2847219A1
(en)
*
|
2012-05-07 |
2015-03-18 |
Amgen Inc. |
Anti-erythropoietin antibodies
|
WO2013169693A1
(en)
|
2012-05-09 |
2013-11-14 |
Bristol-Myers Squibb Company |
Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody
|
EP2882777B1
(en)
|
2012-08-07 |
2018-10-10 |
Roche Glycart AG |
Composition comprising two antibodies engineered to have reduced and increased effector function
|
WO2014072481A1
(en)
|
2012-11-08 |
2014-05-15 |
Novozymes Biopharma Dk A/S |
Albumin variants
|
WO2014139468A1
(en)
|
2013-03-15 |
2014-09-18 |
Admark Healthcare, Llc |
Fusion protein molecules and method of use
|
SG11201508528TA
(en)
|
2013-05-02 |
2015-11-27 |
Anaptysbio Inc |
Antibodies directed against programmed death-1 (pd-1)
|
WO2015000585A1
(en)
*
|
2013-07-02 |
2015-01-08 |
Walter Sebald |
Muteins of cytokines of the gamma-chain receptor family conjugated to a non-protein group
|
US20160237156A1
(en)
|
2013-07-11 |
2016-08-18 |
The California Institute For Biomedical Research |
Immunoglobulin fusion proteins and compositions thereof
|
SG10201804945WA
(en)
|
2013-12-12 |
2018-07-30 |
Shanghai hengrui pharmaceutical co ltd |
Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
KR20160117463A
(ko)
|
2014-02-06 |
2016-10-10 |
에프. 호프만-라 로슈 아게 |
인터루킨-10 면역접합체
|
RU2689160C2
(ru)
|
2014-02-19 |
2019-05-24 |
Мерк Патент Гмбх |
Противораковая таргетная иммунотерапия с применением il-12
|
DK3128997T3
(da)
|
2014-04-08 |
2020-08-24 |
Boston Pharmaceuticals Inc |
Bindingmolekyler specifikke for il-21 og anvendelser deraf
|
CN104403004B
(zh)
|
2014-11-24 |
2017-10-13 |
苏州丁孚靶点生物技术有限公司 |
抗体‑干扰素异二聚体的制备和用途
|
EP3875152B1
(en)
|
2014-12-15 |
2024-04-10 |
Washington University |
Compositions and methods for targeted cytokine delivery
|
US10662240B2
(en)
|
2014-12-19 |
2020-05-26 |
Mabtech Ab |
Composition, kit and method for inhibition of IL-21 mediated activation of human cells
|
US10940212B2
(en)
|
2014-12-19 |
2021-03-09 |
Monash University |
IL-21 agonist antibodies and methods of treatment using same
|
KR20160113452A
(ko)
|
2015-03-20 |
2016-09-29 |
(주)엘지하우시스 |
진공 단열재용 심재 및 진공단열재
|
MX2018001227A
(es)
|
2015-07-30 |
2018-03-26 |
Macrogenics Inc |
Moleculas de union a pd-1 y metodos de uso de las mismas.
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
AU2016303497A1
(en)
|
2015-07-31 |
2018-03-01 |
Tarveda Therapeutics, Inc. |
Compositions and methods for immuno-oncology therapies
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
TWI793062B
(zh)
|
2015-07-31 |
2023-02-21 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
KR102055396B1
(ko)
|
2015-08-11 |
2019-12-12 |
우시 바이올로직스 (케이만) 인코포레이티드 |
신규한 항-pd-1 항체
|
KR102434314B1
(ko)
|
2015-09-01 |
2022-08-19 |
아게누스 인코포레이티드 |
항-pd-1 항체 및 이를 이용하는 방법
|
EP3356404B1
(en)
|
2015-10-02 |
2021-08-18 |
F. Hoffmann-La Roche AG |
Anti-pd1 antibodies and methods of use
|
US10894830B2
(en)
|
2015-11-03 |
2021-01-19 |
Janssen Biotech, Inc. |
Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and their uses
|
WO2017077382A1
(en)
|
2015-11-06 |
2017-05-11 |
Orionis Biosciences Nv |
Bi-functional chimeric proteins and uses thereof
|
US20170174779A1
(en)
*
|
2015-12-22 |
2017-06-22 |
Regeneron Pharmaceuticals, Inc. |
Combination of Anti-PD-1 Antibodies and Anti-CD20/Anti-CD3 Antibodies to Treat Cancer
|
SG10202108724YA
(en)
|
2016-01-08 |
2021-09-29 |
Replimune Ltd |
Modified oncolytic virus
|
US20210000921A1
(en)
|
2016-01-11 |
2021-01-07 |
Flagship Pioneering Innovations V. Inc. |
Methods and compositions for modulating thymic function
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
KR20180101623A
(ko)
|
2016-02-03 |
2018-09-12 |
암젠 리서치 (뮌헨) 게엠베하 |
Psma 및 cd3 이중특이성 t 세포 맞물림 항체 작제물
|
EP3411402B1
(en)
|
2016-02-03 |
2021-12-22 |
Amgen Research (Munich) GmbH |
Bcma and cd3 bispecific t cell engaging antibody constructs
|
JP7220458B2
(ja)
|
2016-02-05 |
2023-02-10 |
ワシントン・ユニバーシティ |
標的サイトカインデリバリーのための組成物および方法
|
WO2017134306A1
(en)
|
2016-02-05 |
2017-08-10 |
Orionis Biosciences Nv |
Cd8 binding agents
|
WO2017158436A1
(en)
|
2016-03-17 |
2017-09-21 |
Oslo Universitetssykehus Hf |
Fusion proteins targeting tumour associated macrophages for treating cancer
|
US11291721B2
(en)
|
2016-03-21 |
2022-04-05 |
Marengo Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
EP3436479A1
(en)
|
2016-04-01 |
2019-02-06 |
Amgen Inc. |
Chimeric receptors to flt3 and methods of use thereof
|
EP3380621A4
(en)
|
2016-04-22 |
2019-05-08 |
Immvira Co., Limited |
CONSTRUCTION OF THE VECTOR OF OBLIGATES ONCOLYTIC HERPES SIMPLEX VIRUSES (OHSV) AND CANCER THERAPY CONSTRUCTIONS
|
BR112019000015A2
(pt)
|
2016-06-30 |
2019-04-24 |
Oncorus, Inc. |
distribuição por vírus oncolítico pseudotipado de polipeptídeos terapêuticos
|
RU2656181C1
(ru)
|
2016-07-13 |
2018-05-31 |
Закрытое Акционерное Общество "Биокад" |
Анти-pd-1-антитела, способ их получения и способ применения
|
CA3032669A1
(en)
|
2016-08-01 |
2018-02-08 |
William Jia |
Oncolytic herpes simplex virus vectors expressing immune system-stimulatory molecules
|
KR101928981B1
(ko)
|
2016-09-02 |
2018-12-13 |
고려대학교 산학협력단 |
항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물
|
BR112019004995A2
(pt)
|
2016-09-14 |
2019-06-04 |
Beijing hanmi pharm co ltd |
anticorpo que se liga especificamente a pd-1 e fragmento funcional do mesmo
|
MX2019003058A
(es)
|
2016-09-21 |
2019-11-28 |
Cstone Pharmaceuticals |
Anticuerpos monoclonales novedosos para muerte programada 1 (pd-1).
|
AU2017331275A1
(en)
|
2016-09-23 |
2019-05-16 |
Oncosec Medical Incorporated |
Modulating responses to checkpoint inhibitor therapy
|
CA3039992A1
(en)
|
2016-11-02 |
2018-05-11 |
Jounce Therapeutics, Inc. |
Antibodies to pd-1 and uses thereof
|
GB201700350D0
(en)
|
2017-01-09 |
2017-02-22 |
Replimune Ltd |
Altered virus
|
CN107082812B
(zh)
|
2017-03-29 |
2018-11-13 |
上海科医联创生物科技有限公司 |
一种恢复衰竭性免疫细胞功能的融合蛋白及其应用
|
PL3606946T3
(pl)
|
2017-04-03 |
2022-11-28 |
F. Hoffmann-La Roche Ag |
Immunokoniugaty przeciwciała anty-PD-1 ze zmutowaną IL-2 lub z IL-15
|
CA3068841A1
(en)
|
2017-07-03 |
2019-01-10 |
Torque Therapeutics, Inc. |
Fusion molecules targeting immune regulatory cells and uses thereof
|
JP2021515599A
(ja)
|
2018-03-09 |
2021-06-24 |
アスクジーン・ファーマ・インコーポレイテッドAskGene Pharma, Inc. |
新規のサイトカインプロドラッグ
|
US20210024631A1
(en)
|
2018-03-28 |
2021-01-28 |
Orionis Biosciences, Inc. |
Bi-functional proteins and construction thereof
|
CA3095920A1
(en)
|
2018-04-10 |
2019-10-17 |
Amgen Inc. |
Chimeric receptors to dll3 and methods of use thereof
|
KR20210021486A
(ko)
|
2018-06-18 |
2021-02-26 |
안위타 바이오사이언시스, 인코포레이티드 |
사이토카인 융합 단백질 및 이의 용도
|
AU2019350466A1
(en)
|
2018-09-28 |
2021-04-29 |
Pierre Fabre Medicament |
New immunocytokines for the treatment of cancer
|
US20220025050A1
(en)
|
2018-12-21 |
2022-01-27 |
Ose Immunotherapeutics |
Bifunctional molecule directed against human pd-1
|