CO2017011536A2 - Composiciones que comprenden una combinación de un anticuerpo anti muerte programada 1 (pd-1) y otro anticuerpo - Google Patents

Composiciones que comprenden una combinación de un anticuerpo anti muerte programada 1 (pd-1) y otro anticuerpo

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Publication number
CO2017011536A2
CO2017011536A2 CONC2017/0011536A CO2017011536A CO2017011536A2 CO 2017011536 A2 CO2017011536 A2 CO 2017011536A2 CO 2017011536 A CO2017011536 A CO 2017011536A CO 2017011536 A2 CO2017011536 A2 CO 2017011536A2
Authority
CO
Colombia
Prior art keywords
antibody
combination
death
composition
compositions
Prior art date
Application number
CONC2017/0011536A
Other languages
English (en)
Inventor
Vikram SADINENI
Yong Quan
Wallace Kaserer
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55809254&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2017011536(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CO2017011536A2 publication Critical patent/CO2017011536A2/es

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    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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Abstract

La presente invención se refiere a composiciones farmacéuticas que comprenden una combinación de un agente contra el cáncer que es un primer anticuerpo y un segundo anticuerpo. En algunas modalidades, el primer anticuerpo es un anticuerpo anti-muerte programada-1 (PD-1). En ciertas modalidades, la composición es una formulación de dosis fija. En ciertas modalidades, la composición se administra como una dosis uniforme. También un kit para tratar un sujeto afectado con una enfermedad, en donde el kit comprende una dosis de cualquier composición descrita en la presente e instrucciones para usar la composición en cualquiera de los métodos descritos para tratar una enfermedad.
CONC2017/0011536A 2015-04-17 2017-11-10 Composiciones que comprenden una combinación de un anticuerpo anti muerte programada 1 (pd-1) y otro anticuerpo CO2017011536A2 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562149325P 2015-04-17 2015-04-17
US201562265268P 2015-12-09 2015-12-09
US201562269000P 2015-12-17 2015-12-17
US201662303855P 2016-03-04 2016-03-04
PCT/US2016/027913 WO2016168716A1 (en) 2015-04-17 2016-04-15 Compositions comprising a combination of an anti-pd-1 antibody and another antibody

Publications (1)

Publication Number Publication Date
CO2017011536A2 true CO2017011536A2 (es) 2018-02-09

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CONC2017/0011536A CO2017011536A2 (es) 2015-04-17 2017-11-10 Composiciones que comprenden una combinación de un anticuerpo anti muerte programada 1 (pd-1) y otro anticuerpo

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US (4) US20160304607A1 (es)
EP (2) EP3738610A1 (es)
JP (3) JP6949718B2 (es)
KR (1) KR20170138477A (es)
CN (2) CN113577264A (es)
AU (2) AU2016249395B2 (es)
BR (1) BR112017021688A2 (es)
CA (1) CA2982839A1 (es)
CL (1) CL2017002636A1 (es)
CO (1) CO2017011536A2 (es)
CY (1) CY1123397T1 (es)
DK (1) DK3283107T3 (es)
EA (1) EA201792273A1 (es)
ES (1) ES2813580T3 (es)
HK (1) HK1247099A1 (es)
HR (1) HRP20201334T1 (es)
HU (1) HUE050894T2 (es)
IL (2) IL255072B (es)
LT (1) LT3283107T (es)
MA (1) MA53243A (es)
MX (2) MX2017013270A (es)
MY (1) MY188749A (es)
PE (1) PE20180394A1 (es)
PH (1) PH12017501774A1 (es)
PL (1) PL3283107T3 (es)
PT (1) PT3283107T (es)
RS (1) RS60753B1 (es)
SG (2) SG11201708223QA (es)
SI (1) SI3283107T1 (es)
TN (1) TN2017000440A1 (es)
TW (3) TWI733664B (es)
WO (1) WO2016168716A1 (es)

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AR072999A1 (es) 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
AR091649A1 (es) 2012-07-02 2015-02-18 Bristol Myers Squibb Co Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
CA2909160C (en) 2013-04-09 2021-05-25 Lixte Biotechnology, Inc. Formulations of oxabicycloheptanes and oxabicycloheptenes
RS58705B1 (sr) 2013-09-20 2019-06-28 Bristol Myers Squibb Co Kombinacija anti-lag-3 antitela i anti-pd-1 antitela za lečenje tumora
EP3049442A4 (en) 2013-09-26 2017-06-28 Costim Pharmaceuticals Inc. Methods for treating hematologic cancers
WO2015173267A1 (en) 2014-05-13 2015-11-19 Medimmune Limited Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small cell lung cancer
PT3148579T (pt) 2014-05-28 2021-03-11 Ludwig Inst For Cancer Res Ltd Anticorpos anti-gitr e métodos da sua utilização
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