CN209451138U - A kind of matrix type application carrying radioactive particle - Google Patents

A kind of matrix type application carrying radioactive particle Download PDF

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Publication number
CN209451138U
CN209451138U CN201821595788.5U CN201821595788U CN209451138U CN 209451138 U CN209451138 U CN 209451138U CN 201821595788 U CN201821595788 U CN 201821595788U CN 209451138 U CN209451138 U CN 209451138U
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particle
layer
storehouse
adhesive layer
particle storehouse
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CN201821595788.5U
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焦德超
李宗明
朱明�
徐苗
杨红
周学良
陈建建
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Abstract

The utility model belongs to the field of medical instrument technology, is related to a kind of matrix type application that can carry radioactive particle, including adherent layer, adhesive layer, drug matrices layer and the protective layer being arranged from top to bottom;The one side of adhesive layer is covered with adherent layer by glue, and another side is fixed with drug matrices layer by glue;Drug matrices layer includes alternately arranged particle storehouse and medicament lumen; particle storehouse and medicament lumen are single side face openings; particle storehouse is fixed on adhesive layer in multiple row longitudinal rows; each column particle storehouse includes the single particle storehouse for particle filled composite parallel to each other; the medicament lumen for filling drug is equipped on adhesive layer between adjacent particles storehouse; the other end in particle storehouse is detachably connected with the plastic strip for closing particle storehouse, and plastic strip is fixedly connected with protective layer;Particle storehouse implantation particle is closed after forming chain structure using plastic strip, to form stringer particle chain closed at both ends.The utility model is structurally reasonable, easy to operate, practical.

Description

A kind of matrix type application carrying radioactive particle
Technical field
The utility model relates to the field of medical instrument technology, specially a kind of matrix type that can carry radioactive particle is applied Patch.
Background technique
The primary treatment scheme of radical-ability surgical resection art infantile tumour, but some lesion resections still have it is swollen The case where tumor micro- infiltration, occurs or residual (showing as tumour positive margin), eventually leads to tumour and recurs quickly in a short time.Chamber Tumour in tumour such as oesophagus and bile duct in road, often because tumour blocking normal human's cavity cause patient's correlation internal organs block into And eating difficulties or obstructive jaundice is caused to occur, eventually lead to death.Clinical usually use appeases nasal feeding nutrition Pipe merging or bile duct internal and external drainage pipe implantation.Cutaneum carcinoma is radiotherapy than more sensitive tumour, and conventional method patient needs Fluconazole ear drops are carried out in hospital for a long time, and since tumour comparison sheet is shallow, the short-term outer radiotherapy of large dosage is easy to cause skin to burst Situations such as rotten, occurs.Tumour such as portal vein tumor thrombus etc. in many cavities of human body, therefore blocking blood vessel causes patient's correlation to be blocked Clinical symptoms mainly open blood vessel using conventional bracket implantation at present, temporary alleviation clinical symptoms, but due to the branch of tumour Growth in frame, short then several weeks, it is long then several months, tumour is just again by blood vessel blockage.
125I or103For Pd particle as a kind of low dose rate radioactive source, ray range is short, and small in size, implanted prosthetics is quick, prevents Shield is simple, in this way can concentrate on effective Radiotherapy dosimetry within the scope of local 1.5cm and influence very on normal surrounding organ It is micro-, the treatment of entity tumor is had been widely used in recent years, but is applied the tumour after cancer surgery excision residual It stays or the supplementary therapy of positive margin, with conventional emitting nasal feeding nutrition tube and bile duct internal and external drainage pipe combines treatment, skin superficial Oncotherapy and combined with conventional stent treatment aspect there is still a need for explore.
Utility model content
The mesh of the utility model is the deficiency in order to solve above-mentioned technology, provides a kind of skeleton that can carry radioactive particle Type application, matrix type application can be combined with conventional emitting nasal feeding nutrition tube and bile duct internal and external drainage pipe, so that Routine nasogastric feeding Pipe nutrient canal and biliary stent are supported with nutrient canal or the therapeutic effect with brachytherapy while drainage, Neng Gouying Used in the oncotherapy of skin superficial, avoid the related complication of the outer radiotherapy of high dose, combined after energy with conventional stent to Play a dual role of opening blood vessel and brachytherapy.
To achieve the goals above, the technical solution that the application uses are as follows: one kind can carry the matrix type of radioactive particle Application, including adherent layer, adhesive layer, drug matrices layer and the protective layer being arranged from top to bottom;
The one side of adhesive layer is covered with adherent layer by the glue coated, and the another side of adhesive layer is fixedly connected by glue There is drug matrices layer, the another side of drug matrices layer is detachably connected matcoveredn;
Drug matrices layer includes alternately arranged particle storehouse and medicament lumen, and particle storehouse and medicament lumen are single-open, grain Sub- storehouse is fixedly installed on adhesive layer in multiple row longitudinal rows, and each column particle storehouse includes multiple parallel to each other for filling grain The single particle storehouse of son is provided with the medicament lumen for filling drug on adhesive layer between adjacent particles storehouse, particle storehouse The plastic strip for closing particle storehouse is removably connected on open end, plastic strip is fixedly connected with protective layer.
The utility model is also characterized by
Wherein, adhesive layer is histocompatbility adhesive layer, and glue is histocompatbility glue, and medicament lumen is medicament slow release type Medicament lumen, protective layer are hydrophilic film protective layer, and adherent layer is to carry on the back close paper adherent layer.
Wherein, application with a thickness of 2~3mm, drug matrices layer with a thickness of 1~1.2mm, the diameter in single particle storehouse is 0.6~0.9mm, the column pitch between multiple row particle storehouse are 0.5~1cm, the interval in each column particle storehouse between single particle storehouse For 0.2~0.5mm.
Wherein, it is filled in particle storehouse125I particle or103Pd particle.
Compared with prior art, the utility model has the beneficial effects that carrying radioactivity grain in 1, the utility model The matrix type application of son can be cut according to the size of tumour and the thickness of emitting nasal feeding nutrition tube, and clinical applicability is strong, and It is easy to operate;2, the matrix type application of the utility model, which can stick in, plays antitumor action at the positive of tumour incisxal edge;3, The matrix type application of the utility model can be adhered to emitting nasal feeding nutrition tube or biliary stent, and implantation human body plays nutrition or drainage Antineoplaston is carried out while effect, and there is strong histocompatbility, has good tolerance to gastric acid, in radiotherapy It can be taken off after task external;4, the matrix type application of the utility model can be adhered in conventional stent, open blood vessel While carry out brachytherapy.
Detailed description of the invention
Fig. 1 is the structural schematic diagram for the matrix type application that the utility model one kind can carry radioactive particle;
Fig. 2 is the sectional view that the utility model one kind can carry drug casing play in the matrix type application of radioactive particle.
In figure: 1, adherent layer;2, adhesive layer;3, drug matrices layer;4, protective layer;5, particle storehouse;6, medicament lumen.
Specific embodiment
Below with reference to the attached drawing in the utility model embodiment, to a specific embodiment of the utility model carry out into The description of one step.
As depicted in figs. 1 and 2, a kind of matrix type application carrying radioactive particle, it is anti-including what is be arranged from top to bottom Adhesion coating 1, adhesive layer 2, drug matrices layer 3 and protective layer 4, adherent layer 1 is for protecting adhesive layer 2 and easily tearing when in use It goes, the one side of adhesive layer 2 is used for medicament-carried casing play 3, and another side is for being pasted onto human body, and drug matrices layer 3 is for storing up Put treatment tumour drug and built-in radioactive particle particle storehouse 5, protective layer 4 be hydrophilic film, for protect drug and Resistance when reducing implantation;
The one side of adhesive layer 2 is covered with adherent layer 1 by the glue coated, and the another side of adhesive layer 2 is fixed by glue It is connected with drug matrices layer 3, the another side of drug matrices layer 3 is detachably connected matcoveredn 4;
Drug matrices layer 3 includes alternately arranged particle storehouse 5 and medicament lumen 6, and particle storehouse 5 and medicament lumen 6 are single side faces Opening, particle storehouse 5 are fixedly installed on adhesive layer 2 in multiple row longitudinal rows, and each column particle storehouse 5 includes multiple parallel to each other For the single particle storehouse of particle filled composite, the drug for filling drug is provided on adhesive layer 2 between adjacent particles storehouse 5 Chamber 6, the plastic strip for closing particle storehouse 5 is removably connected on the open end in particle storehouse 5, and plastic strip and protective layer 4 are solid Fixed connection, particle storehouse 5 are swelled tunnel in the particle that the surface of adhesive layer 2 forms stringer arrangement, are applied in the structure between particle storehouse 5 It is covered with the drug for treating tumour.
Wherein, adhesive layer 2 is histocompatbility adhesive layer, and glue is histocompatbility glue, and medicament lumen 6 is medicament slow release Type medicament lumen, protective layer 4 are hydrophilic film protective layer, and adherent layer 1 is to carry on the back close paper adherent layer.
Wherein, application with a thickness of 2~3mm, drug matrices layer 3 with a thickness of 1~1.2mm, the diameter in single particle storehouse 5 For 0.6~0.9mm, the column pitch between multiple row particle storehouse 5 is 0.5~1cm, in each column particle storehouse 5 between single particle storehouse 5 Between be divided into 0.2~0.5mm.
Wherein, it is filled in particle storehouse 5125I particle or103Pd particle.
When it is implemented, being first turned on the protective layer 4 being detachably connected with drug matrices layer 3, particle storehouse is in one at this time End opening state uses the external radioactive particle of 18G puncture needle125I or103Pd implanting gun, by particle by a push-in particle storehouse It is interior, filled with the drug for treating tumour in medicament lumen 6, it is then stained with protective layer 4, and make the plastics connected on protective layer 4 Item seals particle storehouse 5, can be cut at this time according to the size of tumour and the thickness of emitting nasal feeding nutrition tube.
The adherent layer 1 that the matrix type applies is torn off, then sticks in and plays antitumor action at the positive of tumour incisxal edge, It is directly removed after use;Or it is adhered to emitting nasal feeding nutrition tube or biliary stent, implantation human body plays nutrition or drainage is made With while carry out antineoplaston, after completing brachytherapy task, can be taken off external;Or be adhered in conventional stent, Brachytherapy is carried out while opening blood vessel.
Disclosed above is only specific embodiment of the utility model, but the utility model embodiment is not limited to This, the changes that any person skilled in the art can think of should all fall into the protection scope of the utility model.

Claims (4)

1. the matrix type application that one kind can carry radioactive particle, which is characterized in that including the adherent layer being arranged from top to bottom (1), adhesive layer (2), drug matrices layer (3) and protective layer (4);
The one side of the adhesive layer (2) by coat glue be covered with the adherent layer (1), the adhesive layer (2) it is another Face is fixedly connected with the drug matrices layer (3) by glue, and the another side of the drug matrices layer (3) is detachably connected State protective layer (4);
The drug matrices layer (3) includes alternately arranged particle storehouse (5) and medicament lumen (6), particle storehouse (5) and medicament lumen (6) It is single side face opening, the particle storehouse (5) is fixedly installed on the adhesive layer (2) in multiple row longitudinal rows, each column institute Stating particle storehouse (5) includes multiple single particle storehouses for particle filled composite parallel to each other, is located on the adhesive layer (2) adjacent The medicament lumen (6) for filling drug is provided between the particle storehouse (5), on the open end of the particle storehouse (5) It is removably connected with the plastic strip for closing the particle storehouse (5), the plastic strip is fixedly connected with the protective layer (4).
2. the matrix type application that one kind as described in claim 1 can carry radioactive particle, which is characterized in that the adhesive layer It (2) is histocompatbility adhesive layer, the glue is histocompatbility glue, and the medicament lumen (6) is medicament slow release type drug Chamber, the protective layer (4) are hydrophilic film protective layer, and the adherent layer (1) is to carry on the back close paper adherent layer.
3. the matrix type application that one kind as described in claim 1 can carry radioactive particle, which is characterized in that the application With a thickness of 2~3mm, the drug matrices layer (3) with a thickness of 1~1.2mm, the diameter of the single particle storehouse (5) is 0.6~ 0.9mm, the column pitch between particle storehouse (5) described in multiple row is 0.5~1cm, the single particle in particle storehouse (5) described in each column 0.2~0.5mm is divided between storehouse (5).
4. the matrix type application that one kind as described in claim 1 can carry radioactive particle, which is characterized in that the particle storehouse (5) it is filled with125I particle or103Pd particle.
CN201821595788.5U 2018-09-28 2018-09-28 A kind of matrix type application carrying radioactive particle Active CN209451138U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821595788.5U CN209451138U (en) 2018-09-28 2018-09-28 A kind of matrix type application carrying radioactive particle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821595788.5U CN209451138U (en) 2018-09-28 2018-09-28 A kind of matrix type application carrying radioactive particle

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111249629A (en) * 2020-01-19 2020-06-09 闫鹏 Carried in mouth125Radioactive particle conformal pressed film and its preparation method
CN113694363A (en) * 2021-09-24 2021-11-26 韩雪冰 Radioactive particle implantation fixing device and method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111249629A (en) * 2020-01-19 2020-06-09 闫鹏 Carried in mouth125Radioactive particle conformal pressed film and its preparation method
CN113694363A (en) * 2021-09-24 2021-11-26 韩雪冰 Radioactive particle implantation fixing device and method
CN113694363B (en) * 2021-09-24 2022-12-27 韩雪冰 Radioactive particle implantation fixing device and method

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