CN111249629A - Carried in mouth125Radioactive particle conformal pressed film and its preparation method - Google Patents
Carried in mouth125Radioactive particle conformal pressed film and its preparation method Download PDFInfo
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- CN111249629A CN111249629A CN202010061028.1A CN202010061028A CN111249629A CN 111249629 A CN111249629 A CN 111249629A CN 202010061028 A CN202010061028 A CN 202010061028A CN 111249629 A CN111249629 A CN 111249629A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1002—Intraluminal radiation therapy
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- General Health & Medical Sciences (AREA)
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- Radiation-Therapy Devices (AREA)
Abstract
The invention discloses an oral wearable portable I125The invention discloses a proper-type pressed film of radioactive particles and a preparation method thereof, wherein the proper-type pressed film comprises radioactive particles, model wax wraps the outer sides of a plurality of radioactive particles, a first protective membrane is bonded on one side of the model wax, and an aluminum foil is bonded on one side, far away from the model wax, of the first protective membrane125Compared with the prior treatment mode, the mode of controlling and treating the gingival cancer by the radioactive particle conformal pressed film greatly reduces the adverse reaction of the radiotherapy of the treated patient, and the utility model has simple and convenient installation, can be freely disassembled, can be worn in the ordinary outpatient service, saves the hospitalization time of the patient, finally, the production process of the invention is simple and convenient, the cost is low, the treatment cost is only 1/3 of the traditional treatment,the treatment cost required to be paid by the patient is reduced.
Description
The technical field is as follows:
the invention belongs to the field of treatment of gingival cancer, and particularly relates to an oral wearable portable carrier I125A suitable pressed film of radioactive particles and its preparation method are provided.
Background art:
the gum cancer is a common oral malignant tumor, is the second place in the oral cancer attack of Asian population, and the operation is the main treatment mode, but the operation easily causes the facial deformity of the jaw, and seriously affects the facial beauty and the life quality of the patient. Patients who generally do not receive surgical treatment will choose radiation therapy. However, the external radiation treatment of gingival cancer seriously affects the beauty of the face and the quality of life of a patient due to skin damage and oral mucositis.
Brachytherapy is a technique in which radioisotopes are implanted or placed around the tumor. The central high dose and the rapid dose decay with increasing distance are the biggest features. Isotope I125 is the most commonly used permanent radioisotope implantation in China, and the current technology is to permanently implant I125 radioactive particles into the tumor body through puncture. However, the treatment method has several major defects, 1, the treatment mode is invasive operation, the blood vessels around the gingiva are many, and the blood vessels are easy to be damaged; 2. the cleanness of the oral cavity is strictly ensured after the operation, so that the infection is avoided, and the daily life is inconvenient; 3. after the patient has radioactive damage, the radioactive implant particles can not be taken out; the radioactive particles are easy to generate radiation damage of other organs after falling off from the tumor body; and the treatment cost is higher, and the use is inconvenient.
The invention content is as follows:
the object of the present invention is to solve the above problems by providing an intra-oral wearable carrier I125The radioactive particle conformal pressed film and the preparation method thereof solve the defects of the prior equipment.
In order to solve the above problems, the present invention provides an intra-oral wearable type carrier I125The technical scheme of the preparation method of the radioactive particle conformal pressed film comprises the following steps:
carried in mouth125The radioactive particle conformal pressed film comprises radioactive particles, model wax wraps the outer sides of a plurality of radioactive particles, a first protective film is bonded to one side of the model wax, an aluminum foil is bonded to one side, away from the model wax, of the first protective film, a second protective film is bonded to one side, away from the first protective film, of the aluminum foil, and the first protective film and the second protective film are bonded; and a sealing membrane is bonded on one side of the model wax, which is far away from the first protective membrane.
Preferably, the area of the aluminum foil is larger than the area of the plurality of radioactive particles.
Preferably, the first protective film and the second protective film have the same surface profile.
Preferably, the first protective membrane, the second protective membrane and the sealing membrane are all made of polymer resin materials.
Carried in mouth125The preparation method of the radioactive particle conformal pressed film comprises the following steps:
s1, intraoral impression: the inside of the patient's mouth is cleaned and pretreated, and an intraoral impression is then taken using the impression material, the impression should be complete, and the condition of the intraoral tissue clearly recorded.
S2, model perfusion: pouring a liquid state plaster model into the formed oral impression, completely filling the oral impression with liquid plaster, taking out the plaster from the oral impression after the plaster is solidified, trimming and ensuring that the plaster model has no air bubbles.
S3, fixing the radioactive particles: the radioactive particles are fixed to a predetermined radiation site of the phantom by bonding with a mold wax.
S4, punching the membrane: the radioactive particles are placed on the surface of the plaster mold, and the first protective film is punched using a vacuum laminator so that the surface profile of the first protective film is the same as the profile of the plaster mold, and then the edge is trimmed.
S5, pasting aluminum foil: and pasting the aluminum foil on the first protective film at a position close to the position of the radioactive particles, and ensuring the flatness of the aluminum foil.
S6, film adhesion: and placing the second protective membrane on the first protective membrane, punching by using a vacuum film pressing machine, and trimming the edge of the carrier after punching is finished.
S7, enclosing radioactive particles: and (3) sticking a sealing film on the position where the radioactive particles are exposed outside.
S8, try-on of the carrier: the patient wears the finished wearable carrier in the oral cavity and trims the redundant part of the carrier according to the subjective feeling of the patient
Preferably, in S1, when the oral cavity of the patient is treated, food residues inside the oral cavity of the patient need to be removed.
Preferably, in S2, the gypsum pattern is placed in a gypsum dryer for drying.
Preferably, after the first protection film is punched in S4, the edge of the film needs to be ground to avoid sharp edges.
Preferably, in S6, the second protective film sheet and the first protective film sheet are bonded together and then similarly subjected to an edging process.
The invention has the beneficial effects that:
compared with the conventional treatment mode, the mode of controlling and treating the gingival cancer by using the intraoral wearable I125 radioactive particle conformable squeeze film which is convenient to carry and install greatly reduces the adverse reaction of radiotherapy of a treated patient, has simple and convenient installation and can be freely disassembled, can be worn in a common clinic, saves the hospitalization time of the patient, and finally has simple and convenient production process, low cost and treatment cost which is only 1/3 of the traditional treatment, thereby reducing the treatment cost required by the patient.
Description of the drawings:
for ease of illustration, the invention is described in detail by the following detailed description and the accompanying drawings.
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the preparation process of the present invention.
In the figure: 1. emitting particles; 2. a model wax; 3. a first protective membrane; 4. aluminum foil; 5. a second protective membrane; 6. and sealing the membrane.
The specific implementation mode is as follows:
as shown in fig. 1-2, the following technical solutions are adopted in the present embodiment: carried in mouth125Radiation particle conformal pressed film, including radiation particle 1, the parcel in a plurality of radiation particle 1 outside has model wax 2, and 2 one sides of model wax are bonded and are had first protection diaphragm 3, and the laminating of one side that model wax 2 was kept away from to first protection diaphragm 3 has aluminiumA foil 4, wherein a second protective membrane 5 is attached to one side, away from the first protective membrane 3, of the aluminum foil 4, and the first protective membrane 3 and the second protective membrane 5 are bonded; a sealing membrane 6 is bonded to the mold wax 2 on the side away from the first protective sheet 3.
The area of the aluminum foil 4 is larger than the areas of the plurality of radiation particles 1, so that the radiation emitted by the radiation particles 1 can be weakened by the aluminum foil 4, and the human body is prevented from being damaged greatly.
The surface contours of the first protective film 3 and the second protective film 5 are the same, so that the first protective film can be more suitable for the inner contour of the oral cavity of a patient.
The first protective membrane 3, the second protective membrane 5 and the sealing membrane 6 are made of high polymer resin materials, and the high polymer resin materials have high radiation resistance, can avoid radiation from directly acting on a human body, and cannot cause great damage to the body.
Carried in mouth125The preparation method of the radioactive particle conformal pressed film comprises the following steps:
s1, intraoral impression: the inside of the patient's mouth is cleaned and pretreated, and an intraoral impression is then taken using the impression material, the impression should be complete, and the condition of the intraoral tissue clearly recorded.
S2, model perfusion: pouring a liquid state plaster model into the formed oral impression, completely filling the oral impression with liquid plaster, taking out the plaster from the oral impression after the plaster is solidified, trimming and ensuring that the plaster model has no air bubbles.
S3, fixing the radioactive particles: the radioactive particles 1 are fixed to a predetermined radiation site of the mold by bonding with the mold wax 2.
S4, punching the membrane: the radioactive seeds 1 are placed on the surface of the plaster mold, and the first protective sheet 3 is punched using a vacuum laminator, and the surface profile of the first protective sheet 3 is made the same as the plaster mold profile, and then the edge is trimmed.
S5, pasting aluminum foil: the aluminum foil 4 is stuck to the first protective film 3 at a position close to the radioactive seeds 1, and the flatness of the aluminum foil 4 is ensured.
S6, film adhesion: the second protective film 5 is placed on the first protective film 3 and punched with a vacuum laminator, and the carrier edge is trimmed after punching is completed.
S7, enclosing radioactive particles: the radioactive particles 1 are stuck to the exposed position using a sealing film 6.
S8, try-on of the carrier: the patient wears the finished wearable carrier in the oral cavity and trims the redundant part of the carrier according to the subjective feeling of the patient
In S1, when the oral cavity of the patient is treated, food residue inside the oral cavity of the patient needs to be removed, so that the finish degree of the impression inside the oral cavity is higher.
In the step S2, the gypsum pattern needs to be placed in a gypsum dryer for drying, so as to accelerate the drying of the gypsum pattern and reduce the time required for manufacturing the carrier.
Wherein, need polish the edge of diaphragm after punching press first protection diaphragm 3 in S4, avoid appearing sharp limit, the sharp change of avoiding appearing causes the oppression to patient' S oral cavity, makes the oral cavity be injured.
In S6, the edge grinding process is also required after the second protective film 5 and the first protective film 3 are bonded, and the entire carrier is subjected to edge grinding so that no sharp surface is present on the surface of the carrier.
Specifically, the method comprises the following steps: cleaning and pretreating the inside of the oral cavity of a patient, then using impression material to obtain an oral impression, ensuring the integrity of the impression, clearly recording the condition of the tissues in the mouth, then pouring a liquid gypsum model into the formed oral impression, completely filling the oral impression with liquid gypsum, taking out the oral impression after the gypsum is solidified, trimming the oral impression, then using model wax 2 to bond and fix the radioactive particles 1 on the preset radioactive parts of the model, then manufacturing a carrier part, firstly placing the radioactive particles 1 on the surface of a gypsum mould, stamping a first protective film 3 by using a vacuum film pressing machine, enabling the surface contour of the first protective film 3 to be the same as that of the gypsum mould, trimming the edge, and then pasting an aluminum foil 4 on the first protective film 3 at the position close to the radioactive particles 1, and guarantee the level and smooth of aluminium foil 4, place second protection diaphragm 5 on first protection diaphragm 3 at last, and utilize the vacuum film pressing machine to carry out the punching press, and finish the carrier edge after the punching press is accomplished, the carrier preparation is accomplished, it can to use sealed diaphragm 6 to paste in the exposed outside position of radiation particle 1 at last, then let the patient wear the wear type carrier of completion with processing in the oral cavity, and the unnecessary part on the carrier is pruned according to patient's subjective impression can.
While there have been shown and described what are at present considered to be the fundamental principles of the invention and its essential features and advantages, it will be understood by those skilled in the art that the invention is not limited by the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the invention as defined by the appended claims and their equivalents.
Claims (9)
1. Carried in mouth125A suitable pressed film of radioactive particles comprises radioactive particles (1) and is characterized in that: the outer sides of the plurality of radioactive particles (1) are wrapped with model wax (2), one side of the model wax (2) is bonded with a first protective membrane (3), one side, far away from the model wax (2), of the first protective membrane (3) is bonded with an aluminum foil (4), one side, far away from the first protective membrane (3), of the aluminum foil (4) is bonded with a second protective membrane (5), and the first protective membrane (3) is bonded with the second protective membrane (5); and a sealing membrane (6) is bonded on one side of the model wax (2) far away from the first protective membrane (3).
2. An intra-oral wearable carrier I according to claim 1125The conformal pressed film of the radioactive particles is characterized in that: the area of the aluminum foil (4) is larger than the area of the plurality of radioactive particles (1).
3. An intra-oral wearable carrier I according to claim 1125The conformal pressed film of the radioactive particles is characterized in that:the surface profiles of the first protective membrane (3) and the second protective membrane (5) are identical.
4. An intra-oral wearable carrier I according to claim 1125The conformal pressed film of the radioactive particles is characterized in that: the first protective membrane (3), the second protective membrane (5) and the sealing membrane (6) are all made of high polymer resin materials.
5. Carried in mouth125The preparation method of the radioactive particle conformal pressed film is characterized by comprising the following steps: the method comprises the following steps:
s1, intraoral impression: the inside of the patient's mouth is cleaned and pretreated, and an intraoral impression is then taken using the impression material, the impression should be complete, and the condition of the intraoral tissue clearly recorded.
S2, model perfusion: pouring a liquid state plaster model into the formed oral impression, completely filling the oral impression with liquid plaster, taking out the plaster from the oral impression after the plaster is solidified, trimming and ensuring that the plaster model has no air bubbles.
S3, fixing the radioactive particles: the radioactive particles (1) are adhesively fixed to a predetermined radiation site of a mold by using a mold wax (2).
S4, punching the membrane: placing the radioactive particles (1) on the surface of a plaster mold, punching the first protective membrane (3) by using a vacuum film pressing machine, enabling the surface contour of the first protective membrane (3) to be identical to the contour of the plaster mold, and then trimming the edge.
S5, pasting aluminum foil: and pasting the aluminum foil (4) on the first protective membrane (3) at a position close to the radioactive particles (1) and ensuring the smoothness of the aluminum foil (4).
S6, film adhesion: the second protective film (5) is placed on the first protective film (3) and is punched by a vacuum film pressing machine, and the edge of the carrier is trimmed after punching is completed.
S7, enclosing radioactive particles: the sealing film (6) is used to stick the radioactive particles (1) to the exposed position.
S8, try-on of the carrier: the patient wears the finished wearable carrier in the oral cavity and trims the excess parts of the carrier according to the subjective feeling of the patient.
6. An intra-oral wearable carrier I according to claim 5125The preparation method of the radioactive particle conformal pressed film is characterized by comprising the following steps: when the oral cavity of the patient is treated in the S1, food waste inside the oral cavity of the patient needs to be removed.
7. An intra-oral wearable carrier I according to claim 5125The preparation method of the radioactive particle conformal pressed film is characterized by comprising the following steps: in S2, the gypsum pattern is dried in a gypsum dryer.
8. An intra-oral wearable carrier I according to claim 5125The preparation method of the radioactive particle conformal pressed film is characterized by comprising the following steps: need polish the edge of diaphragm after punching press first protection diaphragm (3) in S4, avoid appearing sharp edge.
9. An intra-oral wearable carrier I according to claim 5125The preparation method of the radioactive particle conformal pressed film is characterized by comprising the following steps: in the step S6, the second protective film (5) and the first protective film (3) are bonded together and then edging process is also required.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010061028.1A CN111249629A (en) | 2020-01-19 | 2020-01-19 | Carried in mouth125Radioactive particle conformal pressed film and its preparation method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010061028.1A CN111249629A (en) | 2020-01-19 | 2020-01-19 | Carried in mouth125Radioactive particle conformal pressed film and its preparation method |
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| CN111249629A true CN111249629A (en) | 2020-06-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010061028.1A Pending CN111249629A (en) | 2020-01-19 | 2020-01-19 | Carried in mouth125Radioactive particle conformal pressed film and its preparation method |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2181662A1 (en) * | 1995-07-21 | 1997-01-22 | Hans Kronholz | Flexible, adaptable plastic bodies with single catheters or catheters embedded at equal distances or sheaths for inserting catheters for radiotherapy |
| EP1284778A1 (en) * | 2000-05-18 | 2003-02-26 | Theragenics Corporation | Catheter attachment and catheter for brachytherapy |
| WO2008124918A1 (en) * | 2007-04-11 | 2008-10-23 | Pharos Life Corporation | Lightsource for soft oral tissue |
| US20110051892A1 (en) * | 2009-09-01 | 2011-03-03 | Izi Medical Products, Llc | Radiation therapy skin marker |
| CN104415379A (en) * | 2013-08-25 | 2015-03-18 | 上海交通大学附属第一人民医院 | Iodine-125 sealed radioactive particle and preparation method thereof |
| CN106730307A (en) * | 2017-01-04 | 2017-05-31 | 成都维宁生物技术有限公司 | Conformal therapy is pasted and its Manufacturing approach and use |
| CN109172022A (en) * | 2018-08-17 | 2019-01-11 | 广州医科大学附属肿瘤医院 | The fixed device of the desensitizing agent of hyperesthesia of dentin's treatment and preparation, forming method |
| CN109260695A (en) * | 2018-09-21 | 2019-01-25 | 沈阳市佳艺义齿加工厂 | Tooth is protected in the production method of oral cavity customized type movement shield tooth and movement obtained |
| CN209451138U (en) * | 2018-09-28 | 2019-10-01 | 焦德超 | A kind of matrix type application carrying radioactive particle |
-
2020
- 2020-01-19 CN CN202010061028.1A patent/CN111249629A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2181662A1 (en) * | 1995-07-21 | 1997-01-22 | Hans Kronholz | Flexible, adaptable plastic bodies with single catheters or catheters embedded at equal distances or sheaths for inserting catheters for radiotherapy |
| EP1284778A1 (en) * | 2000-05-18 | 2003-02-26 | Theragenics Corporation | Catheter attachment and catheter for brachytherapy |
| WO2008124918A1 (en) * | 2007-04-11 | 2008-10-23 | Pharos Life Corporation | Lightsource for soft oral tissue |
| US20110051892A1 (en) * | 2009-09-01 | 2011-03-03 | Izi Medical Products, Llc | Radiation therapy skin marker |
| CN104415379A (en) * | 2013-08-25 | 2015-03-18 | 上海交通大学附属第一人民医院 | Iodine-125 sealed radioactive particle and preparation method thereof |
| CN106730307A (en) * | 2017-01-04 | 2017-05-31 | 成都维宁生物技术有限公司 | Conformal therapy is pasted and its Manufacturing approach and use |
| CN109172022A (en) * | 2018-08-17 | 2019-01-11 | 广州医科大学附属肿瘤医院 | The fixed device of the desensitizing agent of hyperesthesia of dentin's treatment and preparation, forming method |
| CN109260695A (en) * | 2018-09-21 | 2019-01-25 | 沈阳市佳艺义齿加工厂 | Tooth is protected in the production method of oral cavity customized type movement shield tooth and movement obtained |
| CN209451138U (en) * | 2018-09-28 | 2019-10-01 | 焦德超 | A kind of matrix type application carrying radioactive particle |
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Application publication date: 20200609 |
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