CN209451136U - It is a kind of for carrying the conduit of radioactive particle and drug - Google Patents

Abstract

The utility model discloses a kind of for carrying the conduit of radioactive particle and drug, belong to the field of medical instrument technology, including tube body, the tube body is solid, the tube body front end is button loop spline structure, guidewire lumen is offered along the tube length direction in the tube body, the guidewire lumen is closed in the tube body front end, seal wire is equipped in the guidewire lumen, described seal wire one end is fixedly connected on the guidewire lumen front end, multiple radioactive particle storehouses are offered along the tube length direction around the guidewire lumen in the tube body, the tube body is externally provided with slow release layer, the fixator that can prevent the tube body displacement is socketed with outside the tube body tail end；It is small to solve current conduit radioactive particle load capacity, oncotherapy effect is poor and is inconvenient to the problem of operating.

Description

It is a kind of for carrying the conduit of radioactive particle and drug

Technical field

The utility model belongs to the field of medical instrument technology, and in particular to a kind of for carrying radioactive particle and drug Conduit.

Background technique

Malignant obstructive jaundice is to lead to cholangiectasis since tumour blocks or oppresses bile duct, and cause a series of liver functions It can damage, eventually lead to acute liver failure.Patient occur jaundice it is medical when, be often in advanced tumor, surgery without Method excision, such patient often uses Palliative biliary tract prosthesis implantation to restore obstruction of bile duct, but market sale main support is Bare bracket can occur bile duct and send out pernicious again with the extension of time, tumour invades bile duct through bracket mesh again in 3 months Obstruction.

¹²⁵I or¹⁰³For Pd particle as a kind of low dose rate radioactive source, ray range is short, and small in size, implanted prosthetics is quick, prevents Shield is simple, effective Radiotherapy dosimetry is concentrated within the scope of local 1.5cm can play radiotherapy effect and to dirty around normal Device influence is little, has been widely used for the treatment of entity tumor in recent years.Application No. is the patents of 201520513967.X to set Having counted can carry¹²⁵I particle drainage tube, but the drainage tube can carry two rows of radioactive particles, simulated BT-TPS and (closely put Treat treatment planning systems) dose study show integral dose it is relatively low；To reach ideal prescribed dose, needs to extend and put The intracorporeal indwelling time of penetrating property particle chain.In addition, that previously designs carries¹²⁵The particle drainage tube cross section I is ellipse knot Structure, resistance is larger when implantation, and bile is easy to go out at skin to exosmose by drainage tube after being implanted into.Therefore a kind of raising is designed Radioactive particle load capacity improves oncotherapy effect and the conduit of operation is facilitated to be very important.

Utility model content

The purpose of the utility model is to provide a kind of for carrying the conduit of radioactive particle and drug, solves and leads at present Pipe radioactive particle load capacity is small, and oncotherapy effect is poor and is inconvenient to the problem of operating.

The utility model the technical scheme adopted is that a kind of for carrying the conduit of radioactive particle and drug, including Tube body, the tube body are solid, and the tube body front end is button loop spline structure, are opened up in the tube body along the tube length direction There is guidewire lumen, the guidewire lumen is closed in the tube body front end, and seal wire, described seal wire one end are equipped in the guidewire lumen It is fixedly connected on the guidewire lumen front end, is opened up around the guidewire lumen along the tube length direction in the tube body There are multiple radioactive particle storehouses, the tube body is externally provided with slow release layer, and the pipe can be prevented by being socketed with outside the tube body tail end The fixator of body displacement.

The utility model is also characterized by the slow release layer is by nano material and degradable high polymer material mixing spray Layer body made of applying.

The utility model is also characterized by the nano material is galapectite pipe.

The utility model is also characterized by the degradable high polymer material is PGLA.

The utility model is also characterized by the fixator generally umbrella-shaped structure, offered among the fixator Through-hole, the fixator are socketed on outside the tube body by the through-hole.

It is locked the utility model is also characterized by the tube body passes through described fixator one end by clamping piece, it is described Clip bottom both ends are respectively equipped with fixed pin, and the clamping piece is placed on outside the tube body tail end and is inserted by the fixed pin Enter the locking tube body in the tube body.

The utility model is also characterized by the tube length is 45cm.

The utility model is also characterized by the radion storehouse is being closed at the tube body front end 5cm, it is described Radion storehouse closed end is marked equipped with opacity ring.

The utility model is also characterized by the radioactive particle storehouse is three, and three radioactive particle storehouses It is uniformly arranged centered on guidewire lumen.

The beneficial effects of the utility model are: being equipped with a plurality of radioactive particle storehouse in the utility model catheter tube, improve The load capacity of radioactive particle, meanwhile, a plurality of radioactive particle storehouse is placed in tube body, reduces tube body implantation outer diameter, convenient Implant procedure；Tube body trypsin method has slow release layer, can load tumor therapeutic agent in slow release layer, after tube body implants, drug can To be released slowly to tumor locus, slow release speed of medicine can be with brachytherapy biological dosage mutual of radioactive particle Match, to improve local tumor killing effect；The utility model carries out the same of radiotherapy by improving radioactive particle load capacity, part When, by tube body external drug slow releasing function in tumor locus, the two synergistic effect improves oncotherapy effect.

Detailed description of the invention

Fig. 1 is provided by the utility model for carrying the structural schematic diagram of the conduit of radioactive particle and drug；

Fig. 2 is Fig. 1 middle tube body along the direction A-A schematic cross-section；

Fig. 3 is fixator schematic diagram of internal structure in Fig. 1；

Fig. 4 is fixator top view in Fig. 1.

Description of symbols:

1, tube body, 11, guidewire lumen, 12, slow release layer, 13, radioactive particle storehouse, 14, seal wire, 15, fixator, 151, logical Hole, 16, clamping piece, 161, fixed pin, 17, opacity ring label.

Specific embodiment

With reference to the accompanying drawing, a specific embodiment of the utility model is described in detail, it is to be understood that this The protection scope of utility model is not limited by the specific implementation.

It is a kind of for carrying the conduit of radioactive particle and drug, as shown in Figure 1, Figure 2, Figure 3 and Figure 4, including tube body 1, The tube body 1 is solid, and 1 front end of tube body is button loop spline structure, is opened up in the tube body 1 along 1 length direction of tube body There is guidewire lumen 11, the guidewire lumen 11 is closed in 1 front end of tube body, is equipped with seal wire 14, institute in the guidewire lumen 11 Stating seal wire 14 is 0.014inch loach micro-wire, for preventing radioactive particle from shifting, is also convenient for the replacement of conduit, described to lead 14 one end of silk are fixedly connected on 11 front end of guidewire lumen, along the pipe around the guidewire lumen 11 in the tube body 1 1 length direction of body is opened up there are three radioactive particle storehouse 13, and three radioactive particle storehouses 13 are centered on guidewire lumen 11 Uniformly arrangement, the tube body 1 are externally provided with slow release layer 12, and the slow release layer 12 is made of galapectite pipe and PGLA mixing spraying, institute State the fixator 15 for being socketed with outside 1 tail end of tube body and capable of preventing the tube body 1 from shifting, the fixator 15 generally umbrella knot Structure, through-hole 151 is offered among the fixator 15, and the fixator 15 is socketed on outside the tube body 1 by the through-hole 151 Portion, the tube body 1 pass through described 15 one end of fixator and are locked by clamping piece 16, and the 16 bottom both ends of clip are respectively equipped with Fixed pin 161, the clamping piece 16 are placed on outside 1 tail end of tube body and are inserted into the tube body 1 by the fixed pin 161 Lock the tube body 1.

Further, in order to facilitate implant procedure, 1 length of tube body is 45cm.

Further, for the ease of observing under x-ray, the radion storehouse 13 is being sealed at the 1 front end 5cm of tube body It closes, 13 closed end of radion storehouse is equipped with opacity ring label 17.

The application method of the utility model: it is implanted into biliary tract prosthesis (diameter 10mm) in bile duct first, across stenosis of bile duct Area, by the inner cavity of the utility model conduit implantation biliary tract prosthesis, by radion storehouse 13 by an implantation radiation particle；Tube body Be coated with gradually to degrade on 1 and discharge the drug of anti-tumor drug or radio therapy sensitization, can corradiation particle carry out it is anti-swollen Tumor treatment；After tube body 1 implants, drug can be released slowly to tumor locus, and slow release speed of medicine can be with radioactivity grain The brachytherapy biological dosage of son is mutually matched, to improve local tumor killing effect.

Disclosed above is only specific embodiment of the utility model, and still, the utility model embodiment is not limited to This, the changes that any person skilled in the art can think of should all fall into the protection scope of the utility model.

Claims (9)

1. a kind of for carrying the conduit of radioactive particle and drug, which is characterized in that including tube body (1), the tube body (1) is Solid, tube body (1) front end are button loop spline structure, and the tube body (1) is interior to offer seal wire along the tube body (1) length direction Lumen (11), the guidewire lumen (11) are closed in the tube body (1) front end, and seal wire is equipped in the guidewire lumen (11) (14), described seal wire (14) one end is fixedly connected on the guidewire lumen (11) front end, and the tube body (1) is interior in the wire leading pipe Multiple radioactive particle storehouses (13) are offered along the tube body (1) length direction around chamber (11), the tube body (1) is externally provided with slow It releases layer (12), the fixator (15) that the tube body (1) can be prevented to shift is socketed with outside tube body (1) tail end.

2. according to claim 1 for carrying the conduit of radioactive particle and drug, which is characterized in that the slow release layer It (12) is the layer body made of nano material and degradable high polymer material mixing spraying.

3. according to claim 2 for carrying the conduit of radioactive particle and drug, which is characterized in that the nanometer material Material is galapectite pipe.

4. according to claim 2 for carrying the conduit of radioactive particle and drug, which is characterized in that described degradable High molecular material is PGLA.

5. according to claim 1 for carrying the conduit of radioactive particle and drug, which is characterized in that the fixator (15) generally umbrella-shaped structure, fixator (15) centre offer through-hole (151), and the fixator (15) passes through described logical It is external that hole (151) is socketed on the tube body (1).

6. according to claim 1 for carrying the conduit of radioactive particle and drug, which is characterized in that the tube body (1) it passes through the fixator (15) one end to lock by clamping piece (16), clamping piece (16) the bottom both ends are respectively equipped with solid Determine needle (161), the clamping piece (16) is placed on outside the tube body (1) tail end and by described in the fixed pin (161) insertion The locking tube body (1) in tube body (1).

7. according to claim 1 for carrying the conduit of radioactive particle and drug, which is characterized in that the tube body (1) length is 45cm.

8. according to claim 1 for carrying the conduit of radioactive particle and drug, which is characterized in that the radioactivity Particle storehouse (13) is being closed at the tube body (1) front end 5cm, and radioactive particle storehouse (13) closed end is equipped with impermeable X Wire loop marks (17).

9. according to claim 1 for carrying the conduit of radioactive particle and drug, which is characterized in that the radioactivity Particle storehouse (13) is three, and three radioactive particle storehouses (13) are uniformly arranged centered on guidewire lumen (11).