CN1216045A - 具有内皮素受体拮抗效应的n－(2,1,3－苯并噻(噁)二唑基)磺酰胺 - Google Patents

具有内皮素受体拮抗效应的n－(2,1,3－苯并噻(噁)二唑基)磺酰胺 Download PDF

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Publication number
CN1216045A
CN1216045A CN97193775A CN97193775A CN1216045A CN 1216045 A CN1216045 A CN 1216045A CN 97193775 A CN97193775 A CN 97193775A CN 97193775 A CN97193775 A CN 97193775A CN 1216045 A CN1216045 A CN 1216045A
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CN
China
Prior art keywords
formula
compound
amino
thiophene
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN97193775A
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English (en)
Chinese (zh)
Inventor
W·米德尔斯基
M·奥斯瓦尔德
D·多尔师
C·J·施密特格斯
C·威姆
M·克里斯塔德尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of CN1216045A publication Critical patent/CN1216045A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN97193775A 1996-02-24 1997-02-20 具有内皮素受体拮抗效应的n－(2,1,3－苯并噻(噁)二唑基)磺酰胺 Pending CN1216045A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19606980A DE19606980A1 (de) 1996-02-24 1996-02-24 Endothelin-Rezeptor-Antagonisten
DE19606980.7 1996-02-24

Publications (1)

Publication Number Publication Date
CN1216045A true CN1216045A (zh) 1999-05-05

Family

ID=7786338

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97193775A Pending CN1216045A (zh) 1996-02-24 1997-02-20 具有内皮素受体拮抗效应的n－(2,1,3－苯并噻(噁)二唑基)磺酰胺

Country Status (7)

Country Link
EP (1) EP0885219A1 (de)
CN (1) CN1216045A (de)
AR (1) AR005946A1 (de)
AU (1) AU1875697A (de)
DE (1) DE19606980A1 (de)
WO (1) WO1997030996A1 (de)
ZA (1) ZA971474B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6678669B2 (en) 1996-02-09 2004-01-13 Adeza Biomedical Corporation Method for selecting medical and biochemical diagnostic tests using neural network-related applications
DE10155076A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Verwendung von Endothelin-Rezeptor-Antagonisten zur Behandlung von Tumorerkrankungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591761A (en) * 1993-05-20 1997-01-07 Texas Biotechnology Corporation Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
DE19509950A1 (de) * 1995-03-18 1996-09-19 Merck Patent Gmbh Endothelin-Rezeptor-Antagonisten

Also Published As

Publication number Publication date
WO1997030996A1 (de) 1997-08-28
ZA971474B (en) 1997-08-28
DE19606980A1 (de) 1997-08-28
AU1875697A (en) 1997-09-10
EP0885219A1 (de) 1998-12-23
AR005946A1 (es) 1999-07-21

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