CN107614003A - 拟肽大环化合物及其用途 - Google Patents
拟肽大环化合物及其用途 Download PDFInfo
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- CN107614003A CN107614003A CN201680029213.4A CN201680029213A CN107614003A CN 107614003 A CN107614003 A CN 107614003A CN 201680029213 A CN201680029213 A CN 201680029213A CN 107614003 A CN107614003 A CN 107614003A
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- macrocyclic compound
- peptidomimetic macrocyclic
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- alkyl
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4748—Details p53
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| US62/136,357 | 2015-03-20 | ||
| US201562232275P | 2015-09-24 | 2015-09-24 | |
| US62/232,275 | 2015-09-24 | ||
| PCT/US2016/023275 WO2016154058A1 (en) | 2015-03-20 | 2016-03-18 | Peptidomimetic macrocycles and uses thereof |
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| Publication number | Publication date |
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| JP2018516844A (ja) | 2018-06-28 |
| CA2979847A1 (en) | 2016-09-29 |
| AU2016235424A1 (en) | 2017-10-05 |
| KR20170129879A (ko) | 2017-11-27 |
| WO2016154058A1 (en) | 2016-09-29 |
| US20190256559A1 (en) | 2019-08-22 |
| BR112017019738A2 (pt) | 2018-05-29 |
| US10253067B2 (en) | 2019-04-09 |
| SG11201707750YA (en) | 2017-10-30 |
| EP3294318A1 (en) | 2018-03-21 |
| MX2017011834A (es) | 2018-04-11 |
| IL254444A0 (en) | 2017-11-30 |
| EP3294318A4 (en) | 2019-04-03 |
| US20160333049A1 (en) | 2016-11-17 |
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