CN107569497A - A kind of bait type medicine for Cyprinidae aquaculture - Google Patents
A kind of bait type medicine for Cyprinidae aquaculture Download PDFInfo
- Publication number
- CN107569497A CN107569497A CN201710497649.2A CN201710497649A CN107569497A CN 107569497 A CN107569497 A CN 107569497A CN 201710497649 A CN201710497649 A CN 201710497649A CN 107569497 A CN107569497 A CN 107569497A
- Authority
- CN
- China
- Prior art keywords
- weight
- percentage
- bait
- cyprinidae
- aquaculture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Fodder In General (AREA)
Abstract
A kind of bait type medicine for Cyprinidae aquaculture, it is characterized in that the bait type medicine is made up of the auxiliary material that can be used for bait with the terramycin as active component and the second active ingredient compositions, the weight ratio of the terramycin and the second active ingredient compositions is 1:0.6~1.2, second active ingredient compositions are by the tyrosine of percentage by weight 4% 6%, the tryptophan of percentage by weight 4% 6%, the leucine of percentage by weight 13%~18%, the alanine of percentage by weight 5%~7%, the threonine of percentage by weight 2% 3%, the N acetyl L cysteines of percentage by weight 2% 3%, the tributyl 2-acetylcitrate of percentage by weight 1~2% and the glycine composition of surplus.
Description
Technical field
The invention belongs to Medicines in Aquaculture, more particularly to a kind of fish medicine.
Background technology
In aquaculture process, in order to treat and prevent infection typically using the addition bacteriostatic agent in water body or in bait
The mode of antibiotic is added in material, but the former consumes that medication amount is big, and the pollution to environment is also big, therefore generally,
By the way of medicine is added in bait, and terramycin can both have been made as the antibiotic that a kind of cost is cheap, curative effect determines
For water body bacteriostatic agent, the extensive use obtained in bait can be added again.But " " Fourth Ring can be produced after human body intake terramycin
The problem of plain tooth " etc. is difficult to cure, in existing aquaculture technology, is generally required in application terramycin and stop medicine up to 30d
Phase can just be such that its residual in aquatic products body is down to below 100 μ g/kg, make it in aquaculture using there is more serious
Limitation, therefore provide and a kind of can reduce the bait type medicine that terramycin remains in aquatic products body and turn into the prior art urgently
The problem of to be solved.
The content of the invention
To solve aforementioned technical problem, the invention provides a kind of bait type medicine for Cyprinidae aquaculture, its
Be characterised by the bait type medicine by can be used for the auxiliary material of bait and the terramycin as active component and second it is active into
Be grouped compound composition, it is characterised in that the bait type medicine by can be used for the auxiliary material of bait with as the native mould of active component
Element and the second active ingredient compositions composition, second active ingredient compositions by percentage by weight 4%-6% tyrosine,
Percentage by weight 4%-6% tryptophan, the leucine of percentage by weight 13%~18%, the third of percentage by weight 5%~7%
Propylhomoserin, percentage by weight 2%-3% threonine, percentage by weight 2%-3% N-acetyl-L-cysteine, weight percent
The glycine composition of tributyl 2-acetylcitrate and surplus than 1~2%.
Described a kind of bait type medicine for Cyprinidae aquaculture, it is characterized in that terramycin and the second active component
The weight ratio of composition is 1:0.8~1.
Described a kind of bait type medicine for Cyprinidae aquaculture, it is characterized in that second active ingredient combinations
Thing is by the tyrosine of percentage by weight 5%, the tryptophan of percentage by weight 5%, percentage by weight 14%-16% leucine,
The alanine of percentage by weight 6%, percentage by weight 2%-3% threonine, percentage by weight 2%-3% N- acetyl-L-
Cysteine, the tributyl 2-acetylcitrate of percentage by weight 1~2% and the glycine composition of surplus.
Described, it is characterized in that the auxiliary material that can be used for bait is selected from from fish meal, dregs of beans, peanut meal, cotton dregs, vegetable seed
One or more in the dregs of rice, soya-bean oil, premix, flour, rice bran, wheat bran, medical stone.
Described a kind of bait type medicine for Cyprinidae aquaculture, it is characterized in that the medicine is used for the light of Cyprinidae
The cultivation of water fish.
Described a kind of bait type medicine for Cyprinidae aquaculture, it is characterized in that the fresh-water fishes of the Cyprinidae are selected from
Black carp, grass carp, silver carp, bighead, carp, crucian, Tilapia mossambica.
Bait type medicine provided by the invention, passes through the proportioning between preferred terramycin and the second active ingredient compositions
And second each component in active component proportioning, be found surprisingly that by active component and routine can be used for make the auxiliary of bait
When material mixing carries out feeding administration to the cyprinid fish of cultivation, in addition to the antibiotic except can normally play terramycin acts on, also
Fish only internal Determination of oxytetracycline residues can be significantly reduced, is individually given containing the second active component after terramycin administration terminates
During the bait of composition, terramycin can be further improved in fish only internal accretion rate, so as to which soil is greatly reduced
Off-drug period of mycin medicine when applied to aquaculture.Solve problem of the prior art, improve the security of aquatic products.
Tributyl 2-acetylcitrate especially in the second active component, although conventional use generally as plasticizer, in this hair
In bright prescription screening process it has been surprisingly found that in the plasticizer of the citric acid ester type of routine, only when addition acetyl lemon
Lemon acid tributyl during compound amino acid compatibility with that can significantly improve terramycin accretion rate.And when carrying out being formulated preferred,
It has been found that become apparent using its effect during currently preferred formula.
Embodiment
Provided by the present invention for the bait type medicine of aquaculture, prepare in the following manner,
1) using terramycin, the second active ingredient compositions are as the auxiliary material of bait with can mix
2) it will be suppressed in the mixture of step 1) plus after water mixing and produce bait type medicine of the invention after drying into strips.
Used in present embodiment can as bait accessory formula for：
Fish meal 8%, dregs of beans 13%, peanut meal 18.8%, cotton dregs 13%, rapeseed dregs 13%, soya-bean oil 4%, premix 1%,
Flour 13%, rice bran 7%, wheat bran 8%, (above percentage is the weight percent that each component accounts for bait in bait to medical stone 1.2%
Than)
The premix uses the premix of carp 1% of biological feedstuff Co., Ltd of Beijing BDCom production, contains per g premixes
There is following nutritional ingredient：
Vitamin A >=400IU, vitamin D3100~300IU, vitamin E >=7mg, vitamin K3>=0.2mg, vitamin
B1>=0.3mg, vitamin B2>=0.5mg, vitamin B6>=0.22mg, niacinamide >=2.5mg, calcium pantothenate >=2mg, folic acid >=
0.2mg, vitamin C >=8mg, inositol >=7mg, 8~75mg of iron, 0.875~2.5mg of copper, 7~20mg of zinc, 2~10mg of manganese, iodine
>=0.03mg, 0.01~0.05mg of selenium, 0.01~0.2mg of cobalt.
The formula of embodiment 1~6 is as follows
Comparative example 1~6, it is identical with the formula of embodiment 1~6 respectively, but it is added without terramycin
Pharmacological Examples
Using the childhood carp of health, 15.37 ± 0.39g of original body mass, it is divided into experimental group 1~6 and control group,
Experimental group 1~6 feeds the bait type medicine that embodiment 1~6 obtains respectively, and control group will can be used for the auxiliary of bait
Material is fed as conventional bait.
The experiment pool is 86cm × 56cm × 48cm plastics pond, and 15 tail carps, every group of 1 pond are put in a suitable place to breed per pond.Feeding method is
Fed daily using manufactured medicine as bait twice, the time is respectively 9:00 and 18:00, the amount of feeding is about fish body weight every time
3%, equivalent terramycin dosage is 60mh/kg body weight, Feeding time 5d, tests and takes 5 tail test fish at random per pond after terminating,
Internal oxytetracycline residues detection is carried out to it, then experimental group 1~6 is continued to feed the comparative example composition without terramycin,
Control group continues only to feed conventional bait, and every group takes the experiment of 5 tails to carry out internal oxytetracycline residues inspection with fish at random again after lasting 5d
Survey, the average residual quantity of terramycin is 100 inside control group fish after raising 5d using experimental group, and terramycin is residual in experimental group 1~6
Allowance result such as following table.
| Numbering | Experimental group 1 | Experimental group 2 | Experimental group 3 | Experimental group 4 | Experimental group 5 | Experimental group 6 | Control group |
| 5d residual quantities | 31 | 27 | 33 | 29 | 18 | 19 | 100 |
| 10d residual quantities | 0.31 | 0.27 | 0.25 | 0.27 | 0.10 | 0.09 | 2.98 |
As can be seen here, using the bait type medicine of the present invention, terramycin can be substantially reduced in fish only internal residual, and
And when further feeding only has the comparative example of compound amino acid and bait after drug withdrawal, it can also significantly improve the metabolism of terramycin
Rate.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and
All any modification, equivalent and improvement made within principle etc., are all contained within protection scope of the present invention.
Claims (4)
1. a kind of bait type medicine for Cyprinidae aquaculture, it is characterised in that the bait type medicine is by can be used for bait
The auxiliary material of material forms with the terramycin as active component and the second active ingredient compositions, second active ingredient compositions
By percentage by weight 4%-6% tyrosine, percentage by weight 4%-6% tryptophan, percentage by weight 13%~18%
Leucine, the alanine of percentage by weight 5%~7%, percentage by weight 2%-3% threonine, percentage by weight 2%-3%
N-acetyl-L-cysteine, the glycine composition of the tributyl 2-acetylcitrate of percentage by weight 1~2% and surplus.
2. a kind of bait type medicine for Cyprinidae aquaculture as claimed in claim 1, it is characterized in that terramycin and the
The weight ratio of two active ingredient compositions is 1:0.8~1.
A kind of 3. bait type medicine for Cyprinidae aquaculture as claimed in claim 1, it is characterized in that described second lives
Property component composition is by the tyrosine of percentage by weight 5%, the tryptophan of percentage by weight 5%, percentage by weight 14%-16%
Leucine, the alanine of percentage by weight 6%, percentage by weight 2%-3% threonine, percentage by weight 2%-3%'s
N-acetyl-L-cysteine, the tributyl 2-acetylcitrate of percentage by weight 1~2% and the glycine composition of surplus.
4. a kind of bait type medicine for Cyprinidae aquaculture as claimed in claim 1, it is characterized in that the Cyprinidae
Fresh-water fishes are selected from black carp, grass carp, silver carp, bighead, carp, crucian, Tilapia mossambica.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710497649.2A CN107569497A (en) | 2017-06-27 | 2017-06-27 | A kind of bait type medicine for Cyprinidae aquaculture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710497649.2A CN107569497A (en) | 2017-06-27 | 2017-06-27 | A kind of bait type medicine for Cyprinidae aquaculture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107569497A true CN107569497A (en) | 2018-01-12 |
Family
ID=61049560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710497649.2A Pending CN107569497A (en) | 2017-06-27 | 2017-06-27 | A kind of bait type medicine for Cyprinidae aquaculture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107569497A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192372A (en) * | 2015-09-28 | 2015-12-30 | 全椒县花溪湖特种水产合作社 | Black carp premixed feedstuff and preparation method thereof |
-
2017
- 2017-06-27 CN CN201710497649.2A patent/CN107569497A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192372A (en) * | 2015-09-28 | 2015-12-30 | 全椒县花溪湖特种水产合作社 | Black carp premixed feedstuff and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 付同禄等: "饲料添加剂现状及在鱼虾饲料中的利用", 《饲料工业》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Daniel | A review on replacing fish meal in aqua feeds using plant protein sources | |
| Xie et al. | Partial replacement of fish-meal by soy protein concentrate and soybean meal based protein blend for juvenile Pacific white shrimp, Litopenaeus vannamei | |
| Ai et al. | Effects of replacement of fish meal by soybean meal and supplementation of methionine in fish meal/soybean meal‐based diets on growth performance of the southern catfish silurus meridionalis | |
| CN104938866B (en) | A kind of anti-piglet stress with improve the feed additive of intestinal and preparation method and application | |
| AU2019250440B2 (en) | Use of alpha lipoic acid as a feed additive for aquatic animals | |
| Djissou et al. | Use of Moringa oleifera leaves and maggots as protein sources in complete replacement for fish meal in Nile tilapia (Oreochromis niloticus) diets | |
| Yu et al. | Replacement of fish meal by meat and bone meal in diets for juvenile snakehead Ophiocephalus argus | |
| CN107375305A (en) | A kind of medicinal fish composition that can reduce antibiotic residue | |
| CN107158009A (en) | A kind of pharmaceutical composition for aquaculture | |
| CN105815570A (en) | Application of albumin tannate in preparation of feed additive for animals | |
| CN107080111A (en) | A kind of bait type medicine for aquaculture | |
| KR100897488B1 (en) | Feedstuff composition including red shale | |
| KR101684462B1 (en) | A feed additive composition for increasing growth and improving water purification comprising a mixture of tumeric, and stevia as an effective ingredient | |
| CN107569497A (en) | A kind of bait type medicine for Cyprinidae aquaculture | |
| CN107281195A (en) | It is a kind of to reduce the aquaculture pharmaceutical composition of antibiotic residue | |
| CN107158010A (en) | A kind of fish medicine | |
| CN109511820A (en) | A kind of health premixed feed and health mixed fodder applied to laying hen | |
| CN107281194A (en) | A kind of compound medicine for fish culture | |
| Kroeckel et al. | Bioavailability of free lysine and protein-bound lysine from casein and fishmeal in juvenile turbot (Psetta maxima) | |
| CN111802535B (en) | Natural composition for improving anti-stress response of fish and application thereof | |
| CN105685393A (en) | Pig fattening feed capable of improving pig immunity | |
| CN107212155A (en) | A kind of pharmaceutical composition for Cyprinidae man's fish culture | |
| CN107174588A (en) | A kind of medicine for fish culture | |
| CN107455298A (en) | A kind of Cyprinidae person's fish culture pharmaceutical composition that can reduce antibiotic residue | |
| CN111772057A (en) | Natural compound for improving fish anti-stress response and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180112 |