CN107080111A - A kind of bait type medicine for aquaculture - Google Patents
A kind of bait type medicine for aquaculture Download PDFInfo
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- CN107080111A CN107080111A CN201710455398.1A CN201710455398A CN107080111A CN 107080111 A CN107080111 A CN 107080111A CN 201710455398 A CN201710455398 A CN 201710455398A CN 107080111 A CN107080111 A CN 107080111A
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- weight
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- bait
- aquaculture
- type medicine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
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Abstract
A kind of bait type medicine for aquaculture, it is characterized in that the bait type medicine is made up of the auxiliary material that can be used for bait with the tetracycline as active component and the second active ingredient compositions, the weight ratio of the tetracycline and the second active ingredient compositions is 1:0.6~1.2, second active ingredient compositions are by the glutamic acid of percentage by weight 4% 6%, the L-aminobutanedioic acid of percentage by weight 4% 6%, the leucine of percentage by weight 13%~18%, the arginine of percentage by weight 13%~18%, the tyrosine of percentage by weight 2% 3%, the N acetyl L cysteines of percentage by weight 2% 3%, the triethyl citrate of percentage by weight 1~2% and the glycine composition of surplus.
Description
Technical field
The invention belongs to Medicines in Aquaculture, more particularly to a kind of fish medicine.
Background technology
It is general using the addition bacteriostatic agent in water body or in bait in order to treat and prevent infection in aquaculture process
The mode of antibiotic is added in material, but the former consumes medication amount greatly, and it is also big to the pollution of environment, therefore generally,
By the way of medicine is added in bait, and the antibiotic that tetracycline is determined as a kind of with low cost, curative effect can both have been made
For water body bacteriostatic agent, the extensive use obtained in bait can be added again.But can produce " " Fourth Ring after human body intake tetracycline
In the problem of plain tooth " etc. is difficult to cure, existing aquaculture technology, generally required in application tetracycline and stop medicine up to 30d
Phase can just be such that its residual in aquatic products body is down to below 100 μ g/kg, and tetracycline exists more tight in aquaculture application
The limitation of weight, therefore provide and a kind of can reduce the bait type medicine that tetracycline remains in aquatic products body and turn into the prior art
Urgent problem to be solved.
The content of the invention
To solve aforementioned technical problem, the invention provides a kind of bait type medicine for aquaculture, its feature
It is the bait type medicine by can be used for the auxiliary material of bait and the tetracycline as active component and the second active component group
Compound is constituted, and the weight ratio of the tetracycline and the second active ingredient compositions is 1:0.6~1.2, second active component
Composition is by percentage by weight 4%-6% glutamic acid, percentage by weight 4%-6% L-aminobutanedioic acid, percentage by weight 13%
~18% leucine, the arginine of percentage by weight 13%~18%, percentage by weight 2%-3% tyrosine, weight hundred
Divide the N-acetyl-L-cysteine than 2%-3%, the triethyl citrate of percentage by weight 1~2% and the glycine group of surplus
Into.
Described a kind of bait type medicine for aquaculture, it is characterized in that tetracycline and the second active ingredient combinations
The weight ratio of thing is 1:0.8~1.
A kind of described bait type medicine for aquaculture, it is characterized in that second active ingredient compositions by
Glutamic acid, the L-aminobutanedioic acid of percentage by weight 5% of percentage by weight 5%, percentage by weight 15%-16% leucine, weight
Measure percentage 15%-16% arginine, percentage by weight 2%-3% tyrosine, percentage by weight 2%-3% N- second
Acyl-Cys, the triethyl citrate of percentage by weight 1~2% and the glycine composition of surplus.
Described, it is characterized in that the auxiliary material that can be used for bait is selected from from fish meal, dregs of beans, peanut meal, cotton dregs, vegetable seed
One or more in the dregs of rice, soya-bean oil, premix, flour, rice bran, wheat bran, medical stone.
Described a kind of bait type medicine for aquaculture, it is characterized in that the medicine is used for the fresh-water fishes of Cyprinidae
Cultivation.
Described a kind of bait type medicine for aquaculture, it is characterized in that the fresh-water fishes of the Cyprinidae are selected from green grass or young crops
Fish, grass carp, silver carp, bighead, carp, crucian, Tilapia mossambica.
The bait type medicine that the present invention is provided, passes through the proportioning between preferred tetracycline and the second active ingredient compositions
And second each component in active component proportioning, be found surprisingly that and can be used for making the auxiliary of bait with conventional by active component
When material mixing carries out feeding administration to the cyprinid fish of cultivation, in addition to it can normally play the antibiotic of tetracycline and act on, also
Fish only internal tetracycline residue can be significantly reduced, is individually given after tetracycline administration terminates containing the second active component
During the bait of composition, tetracycline can be further improved in fish only internal accretion rate, so as to be greatly reduced four
Off-drug period of ring element medicine when applied to aquaculture.Problem of the prior art is solved, the security of aquatic products is improved.
Triethyl citrate especially in the second active component, although conventional to be used generally as plasticizer, but carried in the present invention
In the medicine of confession, its effect for improving tetracycline accretion rate can be dramatically increased by adding triethyl citrate.And matched somebody with somebody
During Fang Youxuan, it has been found that become apparent using its effect during currently preferred formula.
Embodiment
Provided by the present invention for the bait type medicine of aquaculture, prepare in the following manner,
1) using tetracycline, the second active ingredient compositions are as the auxiliary material of bait with that can mix
2) by step 1) mixture in add water mix after suppress into strips dry after produce the present invention bait type medicine.
Used in present embodiment can as the accessory formula of bait for：
Fish meal 8%, dregs of beans 13%, peanut meal 18.8%, cotton dregs 13%, rapeseed dregs 13%, soya-bean oil 4%, premix 1%,
Flour 13%, rice bran 7%, wheat bran 8%, (above percentage accounts for the weight percent of bait for each component in bait to medical stone 1.2%
Than)
The premix uses the premix of carp 1% that biological feedstuff Co., Ltd of Beijing BDCom produces, and contains per g premixes
There is following nutritional ingredient：
Vitamin A >=400IU, vitamin D3100~300IU, vitamin E >=7mg, vitamin K3>=0.2mg, vitamin
B1>=0.3mg, vitamin B2>=0.5mg, vitamin B6>=0.22mg, niacinamide >=2.5mg, calcium pantothenate >=2mg, folic acid >=
0.2mg, vitamin C >=8mg, inositol >=7mg, 8~75mg of iron, 0.875~2.5mg of copper, 7~20mg of zinc, 2~10mg of manganese, iodine
>=0.03mg, 0.01~0.05mg of selenium, 0.01~0.2mg of cobalt.
The formula of embodiment 1~6 is as follows
Comparative example 1~6, it is identical with the formula of embodiment 1~6 respectively, but it is added without tetracycline
Pharmacological Examples
Using the childhood carp of health, 15.37 ± 0.39g of original body mass is divided into experimental group 1~6 and control group,
Experimental group 1~6 feeds the bait type medicine that embodiment 1~6 is obtained respectively, and control group will can be used for the auxiliary of bait
Material is fed as conventional bait.
The experiment pool is 86cm × 56cm × 48cm plastics pond, and 15 tail carps, every group of 1 pond are put in a suitable place to breed per pond.Feeding method is
The medicine being made is fed twice daily as bait, the time is respectively 9:00 and 18:00, the amount of feeding is about fish body weight every time
3%, it is 60mh/kg body weight to convert into tetracycline dosage, and Feeding time is 5d, and experiment takes 5 tail test fish at random after terminating per pond,
Internal Tetracycline Residues detection is carried out to it, then experimental group 1~6 is continued to feed the comparative example composition without tetracycline,
Control group continues only to feed conventional bait, and every group takes the experiment of 5 tails to carry out internal Tetracycline Residues inspection with fish at random again after lasting 5d
Survey, so that the average residual quantity of the internal tetracycline of control group fish only is 100 after experimental group raising 5d, tetracycline is residual in experimental group 1~6
Allowance result such as following table.
| Numbering | Experimental group 1 | Experimental group 2 | Experimental group 3 | Experimental group 4 | Experimental group 5 | Experimental group 6 | Control group |
| 5d residual quantities | 51 | 37 | 41 | 53 | 49 | 35 | 100 |
| 10d residual quantities | 0.51 | 0.37 | 0.35 | 0.43 | 0.30 | 0.29 | 1.98 |
As can be seen here, using the bait type medicine of the present invention, tetracycline can be substantially reduced in fish only internal residual, and
And when further feeding only has the comparative example of compound amino acid and bait after drug withdrawal, can also significantly improve the metabolism of tetracycline
Rate.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and
Any modifications, equivalent substitutions and improvements made within principle etc., are all contained within protection scope of the present invention.
Claims (6)
1. a kind of bait type medicine for aquaculture, it is characterised in that the bait type medicine is by can be used for bait
Auxiliary material is constituted with the tetracycline and the second active ingredient compositions as active component, the tetracycline and the second active component group
The weight ratio of compound is 1:0.6~1.2, second active ingredient compositions by percentage by weight 4%-6% glutamic acid, again
Amount percentage 4%-6% L-aminobutanedioic acid, the leucine of percentage by weight 13%~18%, percentage by weight 13%~18%
Arginine, percentage by weight 2%-3% tyrosine, percentage by weight 2%-3% N-acetyl-L-cysteine, weight hundred
Divide the triethyl citrate than 1~2% and the glycine composition of surplus.
2. a kind of bait type medicine for aquaculture as claimed in claim 1, it is characterized in that tetracycline and second is lived
Property component composition weight ratio be 1:0.8~1.
3. a kind of bait type medicine for aquaculture as claimed in claim 1, it is characterized in that described second it is active into
Compound is grouped by the glutamic acid of percentage by weight 5%, the L-aminobutanedioic acid of percentage by weight 5%, percentage by weight 15%-16%'s
Leucine, percentage by weight 15%-16% arginine, percentage by weight 2%-3% tyrosine, percentage by weight 2%-
3% N-acetyl-L-cysteine, the triethyl citrate of percentage by weight 1~2% and the glycine composition of surplus.
4. a kind of bait type medicine for aquaculture as claimed in claim 1, it is characterized in that described can be used for bait
The auxiliary material of material is selected from from fish meal, dregs of beans, peanut meal, cotton dregs, rapeseed dregs, soya-bean oil, premix, flour, rice bran, wheat bran, medical stone
In one or more.
5. a kind of bait type medicine for aquaculture as described in Claims 1 to 4 is any, it is characterized in that the medicine
Cultivation for the fresh-water fishes of Cyprinidae.
6. a kind of bait type medicine for aquaculture as claimed in claim 5, it is characterized in that the fresh water of the Cyprinidae
Fish is selected from black carp, grass carp, silver carp, bighead, carp, crucian, Tilapia mossambica.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710455398.1A CN107080111A (en) | 2017-06-16 | 2017-06-16 | A kind of bait type medicine for aquaculture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710455398.1A CN107080111A (en) | 2017-06-16 | 2017-06-16 | A kind of bait type medicine for aquaculture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107080111A true CN107080111A (en) | 2017-08-22 |
Family
ID=59606865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710455398.1A Pending CN107080111A (en) | 2017-06-16 | 2017-06-16 | A kind of bait type medicine for aquaculture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107080111A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110960541A (en) * | 2019-12-13 | 2020-04-07 | 西南大学 | Pharmaceutical composition for penaeus vannamei boone |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192372A (en) * | 2015-09-28 | 2015-12-30 | 全椒县花溪湖特种水产合作社 | Black carp premixed feedstuff and preparation method thereof |
-
2017
- 2017-06-16 CN CN201710455398.1A patent/CN107080111A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192372A (en) * | 2015-09-28 | 2015-12-30 | 全椒县花溪湖特种水产合作社 | Black carp premixed feedstuff and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110960541A (en) * | 2019-12-13 | 2020-04-07 | 西南大学 | Pharmaceutical composition for penaeus vannamei boone |
| CN110960541B (en) * | 2019-12-13 | 2022-10-28 | 西南大学 | Pharmaceutical composition for penaeus vannamei |
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Application publication date: 20170822 |