CN107281418A - A kind of food, functional food or pharmaceutical composition and its production and use - Google Patents

A kind of food, functional food or pharmaceutical composition and its production and use Download PDF

Info

Publication number
CN107281418A
CN107281418A CN201710476767.5A CN201710476767A CN107281418A CN 107281418 A CN107281418 A CN 107281418A CN 201710476767 A CN201710476767 A CN 201710476767A CN 107281418 A CN107281418 A CN 107281418A
Authority
CN
China
Prior art keywords
parts
root
composition
orange peel
chinese yam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201710476767.5A
Other languages
Chinese (zh)
Other versions
CN107281418B (en
Inventor
谢慧
罗霞
王耿
廖逸茹
张瑾
王胜兰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chengdu University of Traditional Chinese Medicine
Original Assignee
Chengdu University of Traditional Chinese Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu University of Traditional Chinese Medicine filed Critical Chengdu University of Traditional Chinese Medicine
Priority to CN201710476767.5A priority Critical patent/CN107281418B/en
Publication of CN107281418A publication Critical patent/CN107281418A/en
Application granted granted Critical
Publication of CN107281418B publication Critical patent/CN107281418B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a kind of food, functional food or pharmaceutical composition, it is by being prepared from containing the raw material that following weight is matched:0.5 1.5 parts of Gorgon fruit, 0.5 1.5 parts of Chinese yam, 0.05 0.15 parts of lotus seeds, 0.1 1 parts of lily, 0.5 1.5 parts of the root of Dahurain angelica, 0.5 1.5 parts of Buddha's hand, 0.1 1 parts of perilla leaf, 0.1 1 parts of peppermint, 0.05 0.15 parts of Fermented Soybean, 0.5 1.5 parts of balloonflower root, 0.05 0.15 parts of coix seed, 0.1 1.5 parts of jujube, 0.005 0.02 parts of rde bean, 0.05 0.15 parts of dried orange peel, 0.005 0.02 parts of Semen Lablab Album, 0.05 0.15 parts of malt, 0.05 0.15 parts of Exocarpium Citri Grandis, 0.05 0.15 parts of hawthorn, 0.05 0.15 parts of peach kernel.Present invention also offers the preparation method of said composition and purposes.Substantially, application prospect is good for present composition clinical remission or treatment infant's respiration systemic disease, protecting the spleen and stomach effect.

Description

A kind of food, functional food or pharmaceutical composition and its production and use
Technical field
The present invention relates to a kind of food, functional food or pharmaceutical composition and its production and use.
Background technology
With the development of the social economy, the idea of prenatal and postnatal care, children's health is the focus of people.Breathing problem Tend to disease of digestive system for the common morbidity of children.And for weakness of the spleen and the stomach children, the infection of usual respiratory tract can be straight The problem of causing digestive system is connect, the characteristics of such as common cold of gastrointestinal type occurs in common susceptible children.Nose is the First Line of respiratory tract, Found in 1 epidemiology survey for west area, the incidence of allergic rhinitis accounts for more than 30%, and next is directed to The retrospective analysis of 10 Nian Nei China allergic rhinitis, it is in stable state to show its incidence of disease.Allergic rhinitis are by sensitization source Caused immune system discharges the allergic disease of inflammatory factor, in close relations with asthma in children, early to find under study for action, The incidence of Asthma with allergic rhinitis is the infant with allergic rhinitis higher than other.Again and, with two tires The opening of policy, the development of medical technology, the quantity of Cesarean esction increases year by year, and at 1, gold U.S. is for Cesarean esction in recent years and suffers from Found in the epidemiology survey of youngster's allergic rhinitis and asthma, Cesarean esction is relevant with children's allergic rhinitis and asthma, and has The infant of family's allergies becomes apparent.So children's substantial amounts with breathing problem, and easily with digestive system Disease.
With the development of the social economy, the quickening and the pollution of environment of urbanization process, the anaphylactia of children be in by The trend that year increases, allergic rhinitis shows as a large amount of clear water sample tears, sneeze etc., and later stage delay can cause chronic rhinosinusitis coexisting, The diseases such as nasal polyp.Intelligence development and body development are influenceed, child suffers from rhinitis for a long time, and respiratory obstruction can make cerebral anoxia and cause Dizzy drowsiness, notice can not be concentrated, school grade declines etc., to the brain of child, including cognitive ability, memory and psychology Activity has significant influence.Not smooth because exhaling in addition, child can be breathed with mouth, can also directly stimulate pharyngeal cavity to cause pharyngitis, grow this It can make that child's lip is thickening in the past, tooth is outwards developed, and causes facial deformity.And doctor trained in Western medicine is used for the allergic rhinitis of children Based on the anti symptom treatments such as antihistamine, hormone and decongestant, but it is repeatedly used for a long and can causes atrophy of nasal turbinates, mycteroxerosis etc. is no Good reaction.The traditional Chinese medical science is for allergic rhinitis and chronic rhinosinusitis coexisting therapeutic effect preferably and without other side effects.
The children physique traditional Chinese medical science thinks easily empty easily real, easily cold easily heat, and it is young be beyond expression, therefore " paediatrics " is called " mute section ", The generation real example of disease then occurs rapidly, and the chronic diseases marked by deficiency of vital energy, which want guardian's carefulness to find that doctor carefully haves a medical check-up, can just be diagnosed, and can not Rapidly treated.So prevention of diseae controls even more important in paediatrics than morbidity.And doctor trained in Western medicine is browsed for allergic rhinitis And the respiratory disease guide such as asthma is to eliminate anaphylactogen, based on Symptomatic medicine.And allergic disease recurrent exerbation, it is many For Long-term taking medicine, children's administration difficulty, such as atomization also more to be mismatched, it is difficult to effectively treatment.
Domestic market has for weakness of the spleen and the stomach food of children such as " fertile youngster's powder ", " spleen-invigorating paste ", but it is only for there is spleen The infant of stomach weakness symptom, it is impossible to be used in because of infection breathing problem, insufficiency of lung-QI influences the infant of taste, pin is still lacked at present To children's allergic rhinitis, the product that chronic rhinosinusitis coexisting is intervened for a long time from food.
The content of the invention
It can alleviate it is an object of the invention to provide one kind or/and treat infant's respiration systemic disease, take into account taste fortune Change, treatment children's lung qi is obstructed, nasal obstruction, food, functional food or pharmaceutical composition of weakness of the spleen and the stomach problem and preparation method thereof And purposes.The invention provides a kind of food, functional food or pharmaceutical composition.
The invention provides a kind of food, functional food or pharmaceutical composition, it is the original by being matched containing following weight Material is prepared from:
0.5-1.5 parts of Gorgon fruit, 0.5-1.5 parts of Chinese yam, 0.05-0.15 parts of lotus seeds, 0.1-1 parts of lily, root of Dahurain angelica 0.5-1.5 Part, 0.5-1.5 parts of Buddha's hand, 0.1-1 parts of perilla leaf, 0.1-1 parts of peppermint, 0.05-0.15 parts of Fermented Soybean, 0.5-1.5 parts of balloonflower root, the heart of a lotus seed 0.05-0.15 parts of the seed of jog's tears, 0.1-1.5 parts of jujube, 0.005-0.02 parts of rde bean, 0.05-0.15 parts of dried orange peel, Semen Lablab Album 0.005- 0.02 part, 0.05-0.15 parts of malt, 0.05-0.15 parts of Exocarpium Citri Grandis, 0.05-0.15 parts of hawthorn, 0.05-0.15 parts of peach kernel.
Wherein, it is that the raw material matched by following weight is prepared from:
1 part of Gorgon fruit, 1 part of Chinese yam, 0.1 part of lotus seeds, 0.5 part of lily, 0.5 part of the root of Dahurain angelica, 0.5 part of Buddha's hand, 0.5 part of perilla leaf, 0.2 part of peppermint, 0.1 part of Fermented Soybean, 1 part of balloonflower root, 0.1 part of coix seed, 0.1 part of jujube, 0.01 part of rde bean, 0.1 part of dried orange peel, in vain 0.01 part of French beans, 0.1 part of malt, 0.1 part of Exocarpium Citri Grandis, 0.1 part of hawthorn, 0.1 part of peach kernel.
Wherein, the Chinese yam is Chinese yam rhizome;The dried orange peel is stir-fry dried orange peel;The malt is coloured malt;The hawthorn is Jiao Hawthorn.
Wherein, it is the primary medicinal powder by the raw material, or water or extractive with organic solvent are active component, and adding to connect The auxiliary material or complementary composition received are prepared into conventional oral formulations.
Wherein, the oral formulations are paste, granule, pulvis, tablet, capsule, oral liquid.
Wherein, the granule is prepared from by the supplementary material of following proportionings:
1 part of Gorgon fruit, 1 part of Chinese yam rhizome, 0.1 part of lotus rice, 0.5 part of lily, 0.5 part of the root of Dahurain angelica, 0.5 part of Buddha's hand, perilla leaf 0.5 Part, 0.2 part of peppermint, 0.1 part of Fermented Soybean, 1 part of balloonflower root, 0.1 part of coix seed, 0.1 part of jujube, 0.01 part of rde bean fries dried orange peel 0.1 Part, 0.01 part of Semen Lablab Album, 0.1 part of coloured malt, 0.1 part of Exocarpium Citri Grandis, 0.1 part of charred FRUCTUS CRATAEGI, 0.1 part of peach kernel, 7 parts of cooked rice flour noodles, white sand 2 parts of sugar.
Present invention also offers the preparation method of above-mentioned composition, it is that the raw material is beaten into powder or water or organic is added Solvent extraction, adds acceptable auxiliary material or complementary composition is prepared from.
Wherein, it comprises the following steps:
A) take Gorgon fruit, it is Chinese yam rhizome, lotus rice, lily, the root of Dahurain angelica, Buddha's hand, perilla leaf, peppermint, Fermented Soybean, balloonflower root, coix seed, big Jujube, rde bean, stir-fry dried orange peel, Semen Lablab Album, coloured malt, Exocarpium Citri Grandis, charred FRUCTUS CRATAEGI, peach kernel, powder is beaten in mixing, standby after sieving;
B) rice is taken, bakees, beat after powder, sieving, the raw material after being sieved with step a is mixed;
C) white granulated sugar or other acceptable auxiliary materials are added or complementary composition is prepared into conventional preparation.
Alleviation or/and treatment infant's respiration systemic disease, digestive system are being prepared present invention also offers above-mentioned composition Purposes in disease, the medicine of deficiency of both lung and spleen or functional food.
Present invention also offers above-mentioned composition prepare alleviate or/and treatment treating infant's rhinitis, nose-nasosinusitis, repeatedly on Purposes in respiratory tract infection, poor appetite, the medicine of morbid night crying of babies sleep terror fright at night or functional food.
Children's visceral-qi is clever clearly, pure-yang constituent, easily empty easily real, and easy cold easily heat, congenital deficiency of kidney-QI, lung defends mistake admittedly, and the day after tomorrow loses In transporting, ailment said due to cold or exposure diseases caused by external factors, rhinocleisis.Nasal conditions for children improve, and should start with terms of lung spleen kidney three, invigorating the spleen helps fortune Change, Gu lung resists exopathogen, kidney tonifying is supported congenital.Gorgon fruit is sweet flat with tonifying spleen and stopping diarrhea, puckery and supplementing the kidney to control the nocturnal, mild in medicine property and, returns spleen kidney two Through.《Plain Questions acupuncture manipulation is discussed》Say:Spleen reality ... being suitable to treat with drugs or foods of sweet-tasteless flavor to be made.Chinese yam is sweet flat,《Sheng Nong's herbal classic》Volume 1 is called it and " in main wound, mended Empty thin ... tonifying middle-Jiao and Qi power, long muscle, long term usage normal hearing and eyesight ", for the product of flat tonifying spleen and stomach, two medicines are monarch drug in a prescription, root of Dahurain angelica pungent-warm solution altogether Table, declares clearing the nasal passage.The pungent row temperature of Buddha's hand lead to, promoting the circulation of qi dampness elimination, the sensible inducing resuscitation of peppermint, perilla leaf warming meridian, helps yang transforming qi, share with Fragrant promoting the circulation of qi, Wen Tonggu lungs, clear the nasal passage is altogether ministerial drug.《The secret record of Feng Shi embroidered purses》" balloonflower root enters lung to volume 5, and can rise to drop.So Exceedingly high gas in tunnel, and without the sorrow of ruffian plug " balloonflower root a surname opens lung qi, tonneau water channel carries all up works into reinforcing earth to generate metal of medicine, For adjutant.Semen Nelumbinis are sweet flat and puckery, are longer than the thick stomach of tonifying spleen, relieving diarrhea with astringents, hawthorn, malt promoting digestion and removing indigestion, share can invigorating the spleen open Stomach, improves a poor appetite.The sweet flat bowl spares of French beans, invigorating the spleen for eliminating dampness, adlay it is sweet it is light be slightly cold, invigorating spleen to remove dampness, the bitter drop of dried orange peel, Exocarpium Citri Grandis pungent-warm Property more increases the effect of our promoting the circulation of qi invigorating the spleen, eliminating dampness and stomach.All medicines share, can the positive lung of sensible promoting the circulation of qi temperature, and can invigorating the spleen disperse accumulations and stomach Clearing damp, invigorating kidney qi.So as to improvement children's nose illness for the treatment of both principal and secondary aspect of disease.
The composition that the present invention is provided can be while improve room Children respiratory system disease such as allergic rhinitis, chronic nose-nose Sinusitis, nasal obstruction etc., repeated cold, asthma etc., transporting and transforming function of the spleen and stomach is taken into account, treatment children's lung qi is obstructed, the problem of weakness of the spleen and the stomach, recovers Spleen and stomach function, it is also effective to infant morbid night crying of babies sleep terror fright at night symptom, fill up the market vacancy.The present invention is integration of drinking and medicinal herbs Chinese medicine group Into, clinical application effect substantially, it is safe and reliable without other additives, can long-term taking, and meet children's traditional food habit Used, in good taste, children's acceptance is high, and the present invention also has the advantages that simple production process, cost are low, is easy to carry.
Embodiment
It is described further below with embodiment, but the present invention is not limited to these embodiments.
The preparation of the present composition of embodiment 1
Prescription content:Gorgon fruit 1g, Chinese yam rhizome 1g, lotus seeds 0.1g, lily 0.5g, root of Dahurain angelica 0.5g, Buddha's hand 0.5g, perilla leaf 0.5g, peppermint 0.2g, Fermented Soybean 0.1g, balloonflower root 1g, coix seed 0.1g, jujube 0.1g, rde bean 0.01g, fry dried orange peel 0.1g, in vain French beans 0.01g, coloured malt 0.1g, Exocarpium Citri Grandis 0.1g, charred FRUCTUS CRATAEGI 0.1g, peach kernel 0.1g.
Technique:
1st, weigh medicinal material by prescription and be laid in baking box, baking box is preheated in advance, with 120 degrees Celsius of constant temperature baking 30min, every 10min is stirred 1 time, it is ensured that medicinal material baking is uniform, to the micro- sallow rear taking-up in medicinal material surface.
2nd, the medicinal material after will be baked dries in the air to normal temperature after taking out, and beats powder, and cross 100 mesh sieves.
3rd, rice low temperature beats powder after bakeing, and crosses 100 mesh sieves, and (add 7g) in proportion mixes with medicinal powder.
4th, medicinal powder is mixed with cooked rice flour noodles after sieving places into baking oven 60-65 degree and is dried, it is to avoid medicinal powder or cooked rice flour noodles knot Block.
5th, auxiliary material white granulated sugar is added:100 mesh sieves are crossed after white granulated sugar is smashed with powder beater, by 2g/ daily doses and medicinal powder and Ground rice is together added.
It is clinical:Once a day, 1 time 15~30 grams, are washed open with boiling water and are adjusted to pasty state and take.Can long-term taking, most Low doses are 15 days.
The preparation of the present composition of embodiment 2
Prescription:Gorgon fruit 0.5g, Chinese yam 0.5g, lotus seeds 0.05g, lily 0.1g, root of Dahurain angelica 0.5g, Buddha's hand 0.5g, perilla leaf 0.1g, peppermint 0.1g, Fermented Soybean 0.05g, balloonflower root 0.5g, coix seed 0.05g, jujube 0.1g, rde bean 0.005g, dried orange peel 0.05g, 0.005g parts of Semen Lablab Album, malt 0.05g, Exocarpium Citri Grandis 0.05g, hawthorn 0.15g, peach kernel 0.15g.
Preparation technology:The preparation technology of be the same as Example 1.
The preparation of the present composition of embodiment 3
Prescription:Gorgon fruit 1.5g, Chinese yam 1.5g, lotus seeds 0.15g, lily 1g, root of Dahurain angelica 1.5g, Buddha's hand 1.5g, perilla leaf 1g are thin Lotus 1g, Fermented Soybean 0.15g, balloonflower root 1.5g, coix seed 0.15g, jujube 1.5g, rde bean 0.02g, dried orange peel 0.15g, Semen Lablab Album 0.02g, malt 0.15g, Exocarpium Citri Grandis 0.15g, hawthorn 0.05g, peach kernel 0.05g.
Preparation technology:The preparation technology of be the same as Example 1.
The preparation of the present composition of embodiment 4
Prescription:The prescription of be the same as Example 1.
Preparation technology:Each bulk drug is weighed by prescription, is crushed, sieving adds cooked rice flour noodles 7g, white granulated sugar 2g, is well mixed, Packing, is produced.
Beneficial effects of the present invention are illustrated below by way of test example.
The clinical observation of the food of the present invention of test example 1, health products or pharmaceutical composition
1st, general information
59, be Hospital Affiliated To Chengdu Traditional Chinese Medicine Univ Pediatric Clinic and Hospitalized Children, and it is small to meet the whole nation in 1987 The diagnostic criteria that respiratory tract meeting is formulated.
Diagnostic criteria:
1. 0~2 years old repetitive upper respiratory tract infection it is annual/7 times;
2. 3~5 years old repetitive upper respiratory tract infection it is annual/6 times;
3. 6~14 years old repetitive upper respiratory tract infection it is annual/5 times.
The concept of repetitive upper respiratory tract infection:Repetitive upper respiratory tract infection is that virus infection is caused mostly, and it is the upper respiratory tract A kind of inflammatory reaction of recurrent exerbation, clinical symptoms to generate heat, have a running nose, beat spray Spray, cough, swallow red, antiadoncus repeatedly Showed Deng to be main.
Control group 29, comes off 1.Man 13, female 14;It is 6 months~10 years old age, average 4.8 years old, annual attack times For 5~13 times.Treatment group 30, man 16, female 14,7 months~10 years old age, average 5.2 years old, and annual attack times are 6~ 13 times.Two groups of courses of disease are 0.4~2 year.Two groups of infants no significant difference (P < in terms of sex, age and the course of disease 0.05), with comparativity.
2nd, treatment method
Control group:Symptomatic treatment (processing of such as bringing down a fever, relieving cough and reducing sputum, fluid infusion treatment, in the case where there is bacterium infection, Antibiotic therapy can be given.Note:The use of the Conventional antibiotic course of disease sick on this has no influence《Paediatrics》).
Treatment group gives infant spleen-tonifying the solid lung nutrition soup (group that i.e. prepared by the method for the embodiment of the present invention 1 under conventional therapy Compound) 1 wrap every time, one time a day, takes after mixing it with hot water, continuously takes March.
3rd, criterion of therapeutical effect
It is effective:3 months courses for the treatment of of medication terminated in later six months, and attack times reduce by more than 2/3, symptom during breaking-out before relatively treating Substantially mitigate, the course for the treatment of substantially shortens.
Effectively:3 months courses for the treatment of of medication terminate number of incidences in later six months and reduce more than 1/2 earlier above, symptom mitigation during morbidity, The course for the treatment of shortens.
It is invalid:Treat sequela number of times to reduce less than 1/2, symptom and the course for the treatment of are not improved during morbidity.
Total effective rate is effective+effective.
4th, result
The treatment group of table 1 is compared with the treatment results of control group
Group Sum It is effective Effectively It is invalid Total effective rate
Control group 29 7 9 13 55.5%
Treatment group 30 12 14 4 86.7%
From table 1, using the treatment group of pharmaceutical composition of the present invention to the total effective rate of repeated respiratory tract infections in children Up to 86.7%, the 55.5% of control group is significantly better than, illustrates that pharmaceutical composition of the present invention has to repeated respiratory tract infections in children There is excellent therapeutic effect.
The sensory evaluation of the food of the present invention of test example 2, health products or pharmaceutical composition
First, the mouthfeel for adding different sugars compares
The product is infant foods, it is not recommended that use food additives, and composition prepared by the embodiment of the present invention 1 is powder Agent, is not suitable for using maltose and honey flavoring, different types of sugar is added and compared.Added respectively in recipe quantity on the one white Sugared 2g, brown sugar 2g, rock sugar 2g carry out mouthfeel contrast, the results are shown in Table 2.
Table 2 adds the products taste of different sugars
It can be seen that, add different types of sugar influences larger to the mouthfeel of the present composition, wherein, during using white sugar 2g, Boiling water reconstitutes rear smell burnt odor, similar to sesame cream in dark brown pasty state, delicate mouthfeel, delicate fragrance naturally, sweetness slightly returns hardship, Mouthfeel is good;And add not good during other carbohydrates, brown sugar is for example added, mouthfeel is bitter;When adding rock sugar, slight bitter, mouthfeel slightly sticks greasy.
2nd, the mouthfeel of addition different amounts white sugar compares
The product is juvenile product, it is not recommended that use food additives, adds white sugar and carries out flavoring, while adding to white sugar Dosage is optimized.0.5g, 1g, 1.5g, 2g, 2.5g white sugar are added in prescription on the one respectively to its original bitter taste and existing sugariness Contrasted, the results are shown in Table 3.
Table 3 adds the products taste of not same amount white sugar
It can be seen that, white sugar consumption is different, and the mouthfeel to the present composition has an impact, wherein, during using white sugar 2g, bitter taste Disappear, sugariness is suitable, and mouthfeel is optimal.
Therefore, present composition mouthfeel is good, edible suitable for children.
To sum up, present composition compatibility rationally, can be used for alleviating various symptoms caused by room Children respiratory system disease, Especially to the evident in efficacy of repeated respiratory tract infections in children, clinical cure rate is high;And present composition security is good, mouthfeel Good, children's acceptance is high, and a kind of new medicament selection is provided for clinic.

Claims (10)

1. a kind of food, functional food or pharmaceutical composition, it is characterised in that:It is the raw material system by being matched containing following weight It is standby to form:
0.5-1.5 parts of Gorgon fruit, 0.5-1.5 parts of Chinese yam, 0.05-0.15 parts of lotus seeds, 0.1-1 parts of lily, 0.5-1.5 parts of the root of Dahurain angelica, Buddhist 0.5-1.5 parts of hand, 0.1-1 parts of perilla leaf, 0.1-1 parts of peppermint, 0.05-0.15 parts of Fermented Soybean, 0.5-1.5 parts of balloonflower root, coix seed 0.05-0.15 parts, 0.1-1.5 parts of jujube, 0.005-0.02 parts of rde bean, 0.05-0.15 parts of dried orange peel, Semen Lablab Album 0.005-0.02 Part, 0.05-0.15 parts of malt, 0.05-0.15 parts of Exocarpium Citri Grandis, 0.05-0.15 parts of hawthorn, 0.05-0.15 parts of peach kernel.
2. composition according to claim 1, it is characterised in that:It is that the raw material matched by following weight is prepared from:
1 part of Gorgon fruit, 1 part of Chinese yam, 0.1 part of lotus seeds, 0.5 part of lily, 0.5 part of the root of Dahurain angelica, 0.5 part of Buddha's hand, 0.5 part of perilla leaf, peppermint 0.2 part, 0.1 part of Fermented Soybean, 1 part of balloonflower root, 0.1 part of coix seed, 0.1 part of jujube, 0.01 part of rde bean, 0.1 part of dried orange peel, Semen Lablab Album 0.01 part, 0.1 part of malt, 0.1 part of Exocarpium Citri Grandis, 0.1 part of hawthorn, 0.1 part of peach kernel.
3. composition according to claim 2, it is characterised in that:The Chinese yam is Chinese yam rhizome;The dried orange peel is stir-fry dried orange peel; The malt is coloured malt;The hawthorn is charred FRUCTUS CRATAEGI.
4. the composition according to claim 1-3 any one, it is characterised in that:It is by the crude drug in whole of the raw material Powder, or water or extractive with organic solvent are active component, add acceptable auxiliary material or complementary composition be prepared into it is conventional Oral formulations.
5. composition according to claim 4, it is characterised in that:The oral formulations are paste, granule, pulvis, piece Agent, capsule, oral liquid.
6. composition according to claim 5, it is characterised in that:The granule by following proportionings supplementary material prepare and Into:
1 part of Gorgon fruit, 1 part of Chinese yam rhizome, 0.1 part of lotus rice, 0.5 part of lily, 0.5 part of the root of Dahurain angelica, 0.5 part of Buddha's hand, 0.5 part of perilla leaf is thin 0.2 part of lotus, 0.1 part of Fermented Soybean, 1 part of balloonflower root, 0.1 part of coix seed, 0.1 part of jujube, 0.01 part of rde bean fries 0.1 part of dried orange peel, in vain 0.01 part of French beans, 0.1 part of coloured malt, 0.1 part of Exocarpium Citri Grandis, 0.1 part of charred FRUCTUS CRATAEGI, 0.1 part of peach kernel, 7 parts of cooked rice flour noodles, 2 parts of white granulated sugar.
7. the preparation method of composition described in claim 1-5 any one, it is characterised in that:It is by the raw material beat powder, Or water or organic solvent extraction are added, add acceptable auxiliary material or complementary composition is prepared from.
8. the preparation method of composition according to claim 7, it is characterised in that:It comprises the following steps:
A) take Gorgon fruit, Chinese yam rhizome, lotus rice, lily, the root of Dahurain angelica, Buddha's hand, perilla leaf, peppermint, Fermented Soybean, balloonflower root, coix seed, jujube, Rde bean, stir-fry dried orange peel, Semen Lablab Album, coloured malt, Exocarpium Citri Grandis, charred FRUCTUS CRATAEGI, peach kernel, powder is beaten in mixing, standby after sieving;
B) rice is taken, bakees, beat after powder, sieving, the raw material after being sieved with step a is mixed;
C) white granulated sugar or other acceptable auxiliary materials are added or complementary composition is prepared into conventional preparation.
9. composition described in claim 1-6 any one is preparing alleviation or/and treatment infant's respiration systemic disease, Digestive Purposes in system disease, the medicine of deficiency of both lung and spleen or functional food.
10. composition described in claim 1-6 any one is preparing alleviation or/and treatment treating infant's rhinitis, chronic nose-nasal sinus Purposes in inflammation, repetitive upper respiratory tract infection, poor appetite, the medicine of morbid night crying of babies sleep terror fright at night or functional food.
CN201710476767.5A 2017-06-21 2017-06-21 Pharmaceutical composition and preparation method and application thereof Active CN107281418B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710476767.5A CN107281418B (en) 2017-06-21 2017-06-21 Pharmaceutical composition and preparation method and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710476767.5A CN107281418B (en) 2017-06-21 2017-06-21 Pharmaceutical composition and preparation method and application thereof

Publications (2)

Publication Number Publication Date
CN107281418A true CN107281418A (en) 2017-10-24
CN107281418B CN107281418B (en) 2021-01-15

Family

ID=60097478

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710476767.5A Active CN107281418B (en) 2017-06-21 2017-06-21 Pharmaceutical composition and preparation method and application thereof

Country Status (1)

Country Link
CN (1) CN107281418B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1947782A (en) * 2006-08-16 2007-04-18 湖南科威制药有限公司 Infantile health-care capsule prepn. method
CN102416038A (en) * 2011-12-09 2012-04-18 上海市中医医院 Chinese medicinal composition for treating infantile recurrent respiratory tract infection
CN103120793A (en) * 2013-01-09 2013-05-29 北京中医药大学东方医院 Traditional Chinese medicine composition for preventing and treating recurrent respiratory tract infection of children and application thereof
CN103830481A (en) * 2014-03-26 2014-06-04 杨巧芝 Medicine for treating recurrent respiratory tract infection of children
CN105853486A (en) * 2016-04-11 2016-08-17 韩秀华 Traditional Chinese medicine preparation for treating children recurrent respiratory infection and preparation method and application thereof
CN106267052A (en) * 2015-06-03 2017-01-04 天津药物研究院有限公司 A kind of medicine treating infantile acute upper respiratory infection and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1947782A (en) * 2006-08-16 2007-04-18 湖南科威制药有限公司 Infantile health-care capsule prepn. method
CN102416038A (en) * 2011-12-09 2012-04-18 上海市中医医院 Chinese medicinal composition for treating infantile recurrent respiratory tract infection
CN103120793A (en) * 2013-01-09 2013-05-29 北京中医药大学东方医院 Traditional Chinese medicine composition for preventing and treating recurrent respiratory tract infection of children and application thereof
CN103830481A (en) * 2014-03-26 2014-06-04 杨巧芝 Medicine for treating recurrent respiratory tract infection of children
CN106267052A (en) * 2015-06-03 2017-01-04 天津药物研究院有限公司 A kind of medicine treating infantile acute upper respiratory infection and preparation method thereof
CN105853486A (en) * 2016-04-11 2016-08-17 韩秀华 Traditional Chinese medicine preparation for treating children recurrent respiratory infection and preparation method and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杜磊等: "《当代中医专科专病治验精华 传染病卷》", 31 December 2013 *

Also Published As

Publication number Publication date
CN107281418B (en) 2021-01-15

Similar Documents

Publication Publication Date Title
CN100450540C (en) External plaster for treating child cold type cough and preparing method
CN104474385A (en) Medicine for treating incoordination between spleen and stomach and preparation method of medicine
CN105362906A (en) Traditional Chinese medicine for treating spleen-stomach deficiency and food stagnation symptoms of children and method for preparing traditional Chinese medicine
CN103719491B (en) A kind of sealwort invigorating the spleen moistening lung health protection tea and preparation method thereof
CN113769029B (en) Medicinal and edible herbal composition for improving intestinal absorption and immune function
CN104667188A (en) Traditional Chinese medicine preparation for treating sphagitis
CN104288477A (en) Traditional Chinese medicine preparation curing infantile asthma
CN101468173B (en) Chinese medicinal composition for treating children's indigestion and preparation method thereof
CN107281418A (en) A kind of food, functional food or pharmaceutical composition and its production and use
CN103007202B (en) Traditional Chinese medicine composition for treating pancreatic cancer
CN104857404A (en) Traditional Chinese medicine preparation for treating pertussis by reducing phlegm and stopping coughing
CN101601822A (en) A kind of medicine for the treatment of infantile cough and laryngeal stridor and preparation method thereof
CN105770705A (en) Medicinal preparation for treating functional dyspepsia of children and application of medicinal preparation
CN104510891A (en) Traditional Chinese medicine composition for treating whooping cough and preparation method thereof
CN104127539A (en) Mussaenda pubescens lozenge and production method thereof
CN1062470C (en) Chinese medicine prepn for infant anorexia
CN106177568A (en) A kind of oral ulcer bag special is made tea and preparation method thereof
CN104840795A (en) Traditional Chinese medicine composition for treating infantile dry cough
CN105770612A (en) Traditional Chinese medicine preparation for treating infantile diarrhea
CN104127504B (en) Infantile common cold cough syrup and preparation method thereof
CN104147095A (en) Pediatric expectorant syrup and preparation method thereof
CN104815143A (en) Traditional Chinese medicine composition for promoting children asthma health, and preparation method thereof
CN104258361A (en) Traditional Chinese medicine composition for treating infantile asthma
CN104491571A (en) Medicament for treating throat pain and thirst and preparation method thereof
CN104147094A (en) Children's bronchitis syrup and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant