CN104825753A - Traditional Chinese medicine composition for control of newborn piglet diarrhea by applying composition to sow - Google Patents
Traditional Chinese medicine composition for control of newborn piglet diarrhea by applying composition to sow Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for control of newborn piglet diarrhea by applying the composition to a sow, the composition comprises the following components: 27-43 parts of angelica, 18-32 parts of safflower, 26-44 parts of forsythia, 24-36 parts of kelp, 23-37 parts of pericarpium citri reticulatae viride, 28-44 parts of pericarpium citri reticulatae, 25-45 parts of cortex moutan, 29-45 parts of rhizoma anemarrhenae, 16-24 parts of poria cocos and 21-35 parts of licorice. The traditional Chinese medicine composition is applied to a newborn sow to achieve the purpose of prevention and treatment of newborn piglet diarrhea, is small in stress, time-saving, labor-saving, and suitable for drug needs for prevention and treatment of newborn piglet diarrhea of scale pig farm assembly line production mode, and can effectively prevent and treat newborn piglet diarrhea caused by a variety of causes.
Description
Technical field
The present invention relates to a kind of veterinary drug, particularly a kind of Chinese medicine composition and preparation method thereof of control newborn piglet diarrhoea of being taken medicine by sow.
Background technology
Newborn piglet diarrhoea is the ubiquitous multifactor property disease of one under intensive pig production working condition, to arrange the milky of special fishy odor or faint yellow loose stool for feature.This disease transmission is fast, and sickness rate, fatality rate are all high, and in whole nest morbidity, even if also growth promoter is slow for the piglet of resistance to mistake, easily forms cad pig, cause serious financial consequences to Swine Production.The generation of this disease may be relevant with the excessive Growth and Reproduction of antibacterial, virus or Enterozoa, and the stimulation that also may cause with nutritional imbalance is relevant, also may be relevant with the increase of intestinal osmotic pressure.Recent studies have found that, the feature of newborn piglet diarrhoea is the normal piglet occurring the 1st week after birth of diarrhoea, and antibiotic therapy is often undesirable, and does not associate with known pathogen.In the last few years, newborn piglet was suffered from diarrhoea, and be on the rise in some areas and the popular of pig farm, become the key factor restricting industry development of raising pigs, the healthy sane development of pig industry in serious threat.
At present; prevent and treat newborn piglet diarrhoea clinically; mainly by improving feeding and management condition, using antibiotic and return the generation that the measures such as the technology of raising reduce newborn piglet diarrhoeal diseases; piglet is mainly made a living with breast milk; oral administration difficulty; and oral administration increases labor intensity one by one, be not suitable for the medication demand of scale pasture pipeline system production model, intramuscular injection simultaneously increases stress again.Secondly, along with the extensive use of antibiotics, particularly non-rational use of drug clinically, cause drug residue and Resistant strain serious all the more, the food-safety problem brought thus causes the concern of the public day by day.Although reasonably return the generation of raising and effectively can control newborn piglet diarrhoea, but this technology is in actual production, be more rambunctious, there is the drawbacks such as artificial loose malicious contaminated environment, the rare outburst accidentally namely may bringing out other latent diseases of biosafety control, results in greater loss.
The Chinese medicine composition of Chinese invention patent application 2011102430301 disclosed treatment piglet severe diarrhoea is by Radix Scutellariae 1 ~ 11 part, 3 ~ 13 parts, Poria, Polyporus 3 ~ 13 parts, Rhizoma Osmundae 1 ~ 9 part, Pericarpium Citri Reticulatae 1 ~ 11 part, Cortex Cinnamomi 1 ~ 10 part.During use be by each for this Chinese medicine composition Chinese medicinal components altogether for smalls, directly gavage piglet.Chinese invention patent application 2012101401560 discloses a kind of herb fermenting preparation and manufacture method thereof of preventing and treating piglet diarrhea, and the parts by weight of this its each component of herb fermenting preparation consist of: Herba Andrographis 10 parts, Pericarpium Granati 8 parts, Fruticose Breyniae Leaf and Twig 8 parts, Herba Portulacae 8 parts, Radix Sophorae Flavescentis 6 parts, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 10 parts; Its use is also take directly to piglet.Obviously there is piglet directly oral very difficult deficiency equally in these medicines, and be not suitable for newborn piglet completely.
Chinese invention patent application number: 201110258204.1 disclose a kind of Chinese medicine composition for preventing and treating newborn piglet diarrhoea, and its medicine consists of: the Radix Pulsatillae 16 parts, Herba Andrographis 8 parts, Radix Sophorae Flavescentis 8 parts, Radix Scutellariae 8 parts, Radix Isatidis 8 parts, Folium Isatidis 10 parts of Radixs Astragali 6 parts, Radix Codonopsis 4 parts, Cortex Phellodendri 6 parts, 5 parts, Poria, Cortex Fraxini 6 parts, Fructus Chebulae 6 parts, the Radix Paeoniae Alba 4 parts, Caulis Akebiae 4 parts, the Radix Aucklandiae 4 parts, 6 parts, Radix Glycyrrhizae.This patent application has heat-clearing and toxic substances removing, anti-inflammation, invigorating the spleen and replenishing QI, spleen invigorating is promoted the production of body fluid, tonifying Qi and lifting yang, dampness removing are regulated the flow of vital energy, lactogenesis and by various functions such as blood breast barrier etc., and be that the mode taken by sow is treated piglet, overcome at first technology foot not.Tradition veterinary is thought, newborn piglet diarrhoea occur many because of female animal heat in blood in puerperal and postnatal blood stasis not to the greatest extent.Because milk is by the life of blood instituteization, female animal heat in blood, blood stasis is stagnated, then milk is unclear.Young stock the intestines and stomach is tender and lovely, and eupepsy is weak, and resistance against diseases is poor, breast milk is suck as crossed, injure gastrointestinal, then affect digestion function of stomach and intestine, can not ascending the clear and descending the turbid, and send out diarrhoea, but 201110258204.1 patent applications for the main rule for the treatment of, inherently can not remove the Disease in Infants pathologic basis of ill piglet, therefore with " heat-clearing and toxic substances removing, anti-inflammation, spleen invigorating promote the production of body fluid ", though there is certain curative effect, probably curative effect is slightly poor to be used for the treatment of newborn piglet diarrhoea.
Summary of the invention
The invention provides one and can overcome prior art deficiency, Chinese medicine composition of a kind of control newborn piglet diarrhoea of being taken medicine by sow and preparation method thereof is provided.
Of the present inventionly a kind ofly comprise following crude drug with parts by weight by the take medicine Chinese medicine composition of control newborn piglet diarrhoea of sow: Radix Angelicae Sinensis 27 – 43 parts, Flos Carthami 18 – 32 parts, Fructus Forsythiae 26 – 44 parts, Thallus Laminariae (Thallus Eckloniae) 24 – 36 parts, Pericarpium Citri Reticulatae Viride 23 – 37 parts, Pericarpium Citri Reticulatae 28 – 44 parts, Cortex Moutan 25 – 45 parts, the Rhizoma Anemarrhenae 29 – 45 parts, Poria 16 – 24 parts, Radix Glycyrrhizae 21 – 35 parts.
The best prescription of Chinese medicine composition of the present invention is: Radix Angelicae Sinensis 35 parts, 25 parts, Flos Carthami, Fructus Forsythiae 35 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, 25 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 30 parts, Cortex Moutan 35 parts, the Rhizoma Anemarrhenae 37 parts, Poria 20 parts, 28 parts, Radix Glycyrrhizae.
Of the present inventionly a kind ofly usually comprise Chinese medicine ingredients and the excipient of aforementioned proportion part by the take medicine Chinese medicine composition of control newborn piglet diarrhoea of sow, as solid carrier, anticaking agents and correctives etc., and according to conventional formulation method, can use after being prepared into the dosage forms such as powder, extractum powder, granule.
Example as the solid carrier of excipient comprises lactose, sucrose, corn starch, starch, cellulose derivative, alginic acid etc.
Example as anticaking agents comprises silicon dioxide, microcrystalline Cellulose, potassium ferrocyanide, sodium aluminosilicate, tricalcium phosphate etc.
Example as correctives comprises glycine, saccharin sodium, cyclamate, aspartame etc.
Further, if needed, Chinese medicine composition of the present invention can contain conventional additives such as correctives, and preferably in employing conventional method system such as powder, a rear use such as material agent, soluble powder etc.This preparation of Chinese medicine composition of the present invention preferably contains the Chinese medicine ingredients of aforementioned proportion part of approximately 20%-100% by weight as effective ingredient.
Chinese medicine composition of the present invention can be conventional Chinese powder medicine form, and its preparation method takes each Chinese medicine component in prescription ratio, and post-drying processed, stirs after pulverizing only, obtains being taken medicine by sow preventing and treating the Chinese medicine composition of newborn piglet diarrhoea through subpackage.The preferred preparation method of the present invention is: after clean system process, adopt this temperature to dry with 65 DEG C of drying and processings be both easy to pulverize, and not easily makes its saccharifying concerning the high medical material of some sugar contents simultaneously, after pulverizing 100 ~ 200 mesh sieves, obtain micropowder powder.
Chinese medicine composition of the present invention also can use Chinese medicinal compound extract extractum powder, its preparation method takes each Chinese medicine component in prescription ratio, after clean remove impurity processed, add the purified water of 8-10 times of medical material weight, decoct three times, each 1 hour, considered, merging filtrate, adopt conventional method simmer down to relative density to be 1.31 ~ 1.35(50 ~ 55 DEG C to relative density) thick paste, spraying dry, pulverizes, add anticaking agents, anti-draw humectant etc., mix and obtain and to be taken medicine the Chinese medicine composition extractum powder that control newborn piglet suffers from diarrhoea by sow.
Chinese medicine composition of the present invention can be Chinese medicine granules form, its preparation method takes each Chinese medicine component in prescription ratio, after clean remove impurity processed, add the purified water of 8-10 times of medical material weight, decoct three times, each 1 hour, considered, merging filtrate, adopt conventional method simmer down to relative density to be 1.31 ~ 1.35(50 ~ 55 DEG C to relative density) thick paste, add appropriate amount of auxiliary materials, as soluble starch, cane sugar powder, lactose etc., make granule, drying, obtain by sow take medicine control newborn piglet diarrhoea Chinese medicinal composition granules.Beneficial effect of the present invention and advantage as follows: 1) the present invention is directed to the relation between newborn piglet diarrhoea and its sow physiological pathology feature that blood stasis does not disappear puerperal, select Radix Angelicae Sinensis, Flos Carthami, Fructus Forsythiae, Thallus Laminariae (Thallus Eckloniae), Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, Cortex Moutan, the Rhizoma Anemarrhenae, the Chinese medicine such as Poria and Radix Glycyrrhizae, by each medicine compatibility, reach the effect of " blood circulation promoting and blood stasis dispelling, clearing away heat and promoting diuresis ", the overall physiological function state of adjustment sow, improve sow milk performance and milk quality, to strengthen piglet immunological phylactic power defensive power, restore piglet gastrointestinal system function, the object of Da Dao More disease.2) to be taken medicine control newborn piglet diarrhoea by newborn sow, stress be little, time and labour saving, is applicable to the medication demand of preventing and treating newborn piglet diarrhoea under Large-scale pig farm production line balance pattern.
Detailed description of the invention
Hereinafter, by providing preparation example and test example explains the present invention in detail, but the present invention is not limited to these embodiments.Below in an example, term " part " refers to weight portion.
Preparation example 1.
Taken medicine by sow and prevent and treat a preparation method for the Chinese medicine composition that newborn piglet is suffered from diarrhoea, comprise the following steps: in prescription ratio, take Radix Angelicae Sinensis 35 parts, 25 parts, Flos Carthami, Fructus Forsythiae 35 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, 25 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 30 parts, Cortex Moutan 35 parts, the Rhizoma Anemarrhenae 37 parts, Poria 20 parts, 28 parts, Radix Glycyrrhizae, clean system, 65 DEG C of oven dry, micronizing crosses 150 mesh sieves, stir, subpackage, obtain by sow take medicine control newborn piglet diarrhoea Chinese medicine composition.
Preparation example 2.
A kind of preparation method of the Chinese medicine composition preventing and treating newborn piglet diarrhoea of being taken medicine by sow, comprise the following steps: in prescription ratio, take Radix Angelicae Sinensis 35 parts, 25 parts, Flos Carthami, Fructus Forsythiae 35 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, 25 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 30 parts, Cortex Moutan 35 parts, the Rhizoma Anemarrhenae 37 parts, Poria 20 parts, 28 parts, Radix Glycyrrhizae, after clean remove impurity processed, add the purified water of 8-10 times of medical material weight, decoct three times, each 1 hour, considered, merging filtrate, adopt conventional method simmer down to relative density to be 1.31 ~ 1.35(50 ~ 55 DEG C to relative density) thick paste, spraying dry, pulverize, add anticaking agents, resist and draw humectant etc., mix and obtain by sow take medicine control newborn piglet diarrhoea Chinese medicine composition extractum powder.
Preparation example 3.
A kind of preparation method of the Chinese medicine composition preventing and treating newborn piglet diarrhoea of being taken medicine by sow, comprise the following steps: in prescription ratio, take Radix Angelicae Sinensis 43 parts, 32 parts, Flos Carthami, Fructus Forsythiae 44 parts, Thallus Laminariae (Thallus Eckloniae) 36 parts, 37 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 44 parts, Cortex Moutan 45 parts, the Rhizoma Anemarrhenae 45 parts, Poria 24 parts, 35 parts, Radix Glycyrrhizae, after clean remove impurity processed, add the purified water of 8-10 times of medical material weight, decoct three times, each 1 hour, considered, merging filtrate, adopt conventional method simmer down to relative density to be 1.31 ~ 1.35(50 ~ 55 DEG C to relative density) thick paste, add appropriate amount of auxiliary materials, as soluble starch, cane sugar powder, lactose etc., make granule, dry, obtain by sow take medicine control newborn piglet diarrhoea Chinese medicinal composition granules.
Following test example proves the useful prevention effect that Chinese medicine composition of the present invention is suffered from diarrhoea for newborn piglet, using preparation example 1 as supplying reagent thing.
The clinical experimental study of embodiment 1. Chinese medicine composition prevention of the present invention newborn piglet diarrhoea
1. the suburbs, test site Lanzhou Large-scale pig farm; sow livestock on hand 200, before test, there is the diarrhoeal diseases of unknown cause in the delivery room piglet on this pig farm; adopt conventional control measure (as improved delivery room management measure, antibiotic therapy and oresol etc.), all without obvious effect.
2. experimental animal chooses parity, body weight, age, litter size, 24 newborn sows that term is close, is divided into 2 groups at random, is respectively Chinese medicine composition group of the present invention and matched group.The sow immunization program included in is consistent, and trimester of pregnancy is consistent with feeding and management condition in puerperal, is the spacing raising in single hurdle.
3. testing program
3.1 therapeutic schemes adopt mixed feeding oral administration, and selected sow, puerperal, with the dosage of every part 400 grams, this product is placed on the wheat bran/feedstuff in crib, after on this medicine, sprinkle wheat bran wheat bran/feedstuff, allow sow search for food completely, every day is administered once, and is used in conjunction three days.
3.2 newborn piglets diarrhoea diagnostic criterias: (1) feces character changes, and in atherosclerotic or watery diarrhea, yellow skin is white, yellowish green or greyish white, or foul smelling; (2) defecation frequency significantly increases; (3) disease time 1 – 7 days; (4) disease such as abdominal distention, stomachache is accompanied.Possess symptom under (1), (2) and (3) item, be namely diagnosed as newborn piglet diarrhoea.
The situation such as 3.3 observation index conscientious observed and recorded piglet every day feces, spirit, appetite, morbidity, and measure the average weigth at birth of piglet and the average weight of weaning litter of 23 ages in days.Newborn piglet diarrhoea case is made a definite diagnosis according to following diagnostic criteria.
4. date processing adopts SPSSV17.0 to carry out data analysis.Cure rate and efficient diversity between each group are evaluated in X 2 test, and all statistical test all adopt two-sided test,
p< 0.05 thinks that the difference of inspection has statistical significance.
5. results and analysis
Chinese medicine composition of the present invention to take medicine the effect of prevention newborn piglet diarrhoea puerperal in table 1 by sow.Compare with matched group, the newborn piglet of trouble in Chinese medicine composition group of the present invention diarrhoea significantly reduces, difference extremely significantly (
p<0.01); Death rate newborn piglet in Chinese medicine composition of the present invention turned group during on 23rd significantly declines, difference extremely significantly (
p<0.01); The birth counterpoise bringing piglet in two groups into is suitable, without significant difference (
p>0.05), and 23 days wean time, the piglet average weight in Chinese medicine composition group of the present invention higher than the piglet counterpoise in matched group, significant difference (
p<0.05).Show, Chinese medicine composition of the present invention is taken medicine by sow puerperal, can effectively prevent newborn piglet to suffer from diarrhoea, and can significantly improve the average weight of piglet when 23 ages in days wean.
The clinical experimental study of embodiment 2. traditional Chinese medicine composition for treating newborn piglet diarrhoea of the present invention
1. the suburbs, test site Lanzhou Large-scale pig farm, sow livestock on hand about 200.
2. experimental animal chooses parity, body weight, age, litter size, the close newborn sow of term, the age in days of the pig that farrows in 1 ~ 7 day, naturally-occurring diarrhoea card, and present the morbidity of whole nest.
3. newborn piglet diarrhoea diagnostic criteria and curative effect determinate standard
3.1 diagnostic criterias (1) feces character changes, and in atherosclerotic or watery diarrhea, yellow skin is white, yellowish green or greyish white, or foul smelling; (2) defecation frequency significantly increases; (3) disease time 1 – 7 days; (4) disease such as abdominal distention, stomachache is accompanied.Possess symptom under (1), (2) and (3) item, be namely diagnosed as newborn piglet diarrhoea.
3.2 the standard of curative effect evaluation
Healing: affected pig is spiritual, the extensive place of appetite is normal, and excrement is bar shaped or graininess, anus drying, contraction, nothing redness.
Effective: affected pig spirit, appetite make moderate progress, and excrement slightly thickens, and dysentery number of times reduces, and anus redness does not disappear.
Invalid: disease of having loose bowels has no to alleviate and even increases the weight of, dead in therapeutic process.
3. therapeutic scheme and observation index
30 selected newborn sows are divided into 2 groups at random, often organize 15, the newborn sow of Chinese medicine composition group of the present invention, with the dosage of every part 400 grams, this product is placed on the wheat bran/feedstuff in crib, after on this medicine, sprinkle wheat bran wheat bran/feedstuff, allow sow free choice feeding, every day is administered once, depending on piglet diarrhea situation, and medication 1 – 3 times; If ill newborn piglet is not sucked the breast, then fed by human assistance and feed the sow milk of Chinese medicine composition of the present invention.Matched group adopts the Conventional treatment regimens on this pig farm, newborn piglet: norfloxacin oral liquid: body weight 5 below kg 1 mL/ time, 5 – 10 kg body weight 2 mL/ time, administered by oral gavage; The person of being in a bad way can take 1 time again after 6 h; Oresol: after dissolving, gives piglet 5 – 10mL.If find that newborn sow suffers from mastitis, then give sow: Herba Houttuyniae injectio 20 mL/ head, ofloxacin injection: 0.1 – 0.2 mL/kg, intramuscular injection, 1 –, 2 times/d, is used in conjunction 2 – 3d.Every day conscientious observed and recorded piglet feces, spirit, appetite, the situation such as morbidity.
4. statistical analysis
Test data SPSS V17.0 analyzes.The cure rate of test group and matched group and total effective rate with card side (
x 2 ) inspection relative analysis.
5. results and analysis
The effect that Chinese medicine composition of the present invention is suffered from diarrhoea by sow medication treatment in puerperal newborn piglet is in table 2.Two groups are compared, sickness rate no significant difference (
p>0.05), illustrate that two groups of baselines have comparability.Compare with matched group, cure rate and the total effective rate of traditional Chinese medicine composition for treating newborn piglet diarrheic syndromes of the present invention are significantly increased, difference extremely significantly (
p<0.001).Show that this religious name Chinese medicine composition to be taken medicine by sow puerperal and effectively can treat newborn piglet diarrhoea.
Conclusion: above-described embodiment result shows, Chinese medicine composition of the present invention to be taken medicine by sow puerperal effectively can treat newborn piglet diarrhoea.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. one kind by sow take medicine control newborn piglet diarrhoea Chinese medicine composition, it is characterized in that: described Chinese medicine composition comprises the following crude drug with parts by weight: Radix Angelicae Sinensis 27 – 43 parts, Flos Carthami 18 – 32 parts, Fructus Forsythiae 26 – 44 parts, Thallus Laminariae (Thallus Eckloniae) 24 – 36 parts, Pericarpium Citri Reticulatae Viride 23 – 37 parts, Pericarpium Citri Reticulatae 28 – 44 parts, Cortex Moutan 25 – 45 parts, the Rhizoma Anemarrhenae 29 – 45 parts, Poria 16 – 24 parts, Radix Glycyrrhizae 21 – 35 parts.
2. the Chinese medicine composition of a kind of control newborn piglet diarrhoea of being taken medicine by sow according to claim 1, is characterized in that Radix Angelicae Sinensis 35 parts, 25 parts, Flos Carthami, Fructus Forsythiae 35 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, 25 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 30 parts, Cortex Moutan 35 parts, the Rhizoma Anemarrhenae 37 parts, Poria 20 parts, 28 parts, Radix Glycyrrhizae.
3. described in claim 1 or 2 any one by sow take medicine control newborn piglet diarrhoea Chinese medicine composition preparation method, it is characterized in that taking each Chinese medicine component in prescription ratio same, clean post-drying processed, stir after pulverizing, obtain being taken medicine by sow preventing and treating the Chinese medicine composition of newborn piglet diarrhoea through subpackage.
4. preparation method according to claim 3, is characterized in that only making rear 65 DEG C of drying and processings, crosses 100 ~ 200 mesh sieves after pulverizing.
5. the preparation method of any one Chinese medicine composition preventing and treating newborn piglet diarrhoea of being taken medicine by sow described in claim 1 or 2, it is characterized in that: take each Chinese medicine component in prescription ratio, after clean remove impurity processed, add the purified water of 8-10 times of medical material weight, decoct three times, each 1 hour, considered, merging filtrate, adopt conventional method simmer down to relative density to be 1.31 ~ 1.35(50 ~ 55 DEG C to relative density) thick paste, spraying dry, pulverize, add anticaking agents, resist and draw humectant etc., mix and obtain by sow take medicine control newborn piglet diarrhoea Chinese medicine composition extractum powder.
6. the preparation method of any one Chinese medicine composition preventing and treating newborn piglet diarrhoea of being taken medicine by sow described in claim 1 or 2, it is characterized in that: take each Chinese medicine component in prescription ratio, after clean remove impurity processed, add the purified water of 8-10 times of medical material weight, decoct three times, each 1 hour, considered, merging filtrate, adopt conventional method simmer down to relative density to be 1.31 ~ 1.35(50 ~ 55 DEG C to relative density) thick paste, add appropriate soluble starch, cane sugar powder, the adjuvants such as lactose, make granule, dry, obtain by sow take medicine control newborn piglet diarrhoea Chinese medicinal composition granules.
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| CN105816563A (en) * | 2016-05-20 | 2016-08-03 | 山东德州神牛药业有限公司 | Application of traditional Chinese medicine composition in preparing drugs for improving reproductive performance of sows |
| CN106822890A (en) * | 2017-01-19 | 2017-06-13 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pharmaceutical composition for preventing and treating diarrhea of weaned piglets and its preparation method and application |
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| JP2005314280A (en) * | 2004-04-28 | 2005-11-10 | Nippon Beet Sugar Mfg Co Ltd | Immunoactivator for livestock in lactation period and starter containing the same |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816563A (en) * | 2016-05-20 | 2016-08-03 | 山东德州神牛药业有限公司 | Application of traditional Chinese medicine composition in preparing drugs for improving reproductive performance of sows |
| CN105816563B (en) * | 2016-05-20 | 2019-07-23 | 山东德州神牛药业有限公司 | A kind of Chinese medicine composition improves the application in sow reproductive performance drug in preparation |
| CN106822890A (en) * | 2017-01-19 | 2017-06-13 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pharmaceutical composition for preventing and treating diarrhea of weaned piglets and its preparation method and application |
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