CN101905014A - Traditional Chinese medicine compound composition for treating diarrhea of weaned piglets - Google Patents
Traditional Chinese medicine compound composition for treating diarrhea of weaned piglets Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine compound composition for treating the diarrhea of weaned piglets. The composition is prepared by mixing the following traditional Chinese medicine raw materials with distilled water, decocting, filtering, removing impurities, mixing filtrate, concentrating under reduced pressure and drying, wherein the traditional Chinese medicine raw materials comprise: 50 to 70g of codonopsis, 50 to 70g of astragalus, 50 to 70g of licorice (fried), 30 to 50g of white atractylodes, 20 to 40g of poria, 20 to 40g of dried ginger, 30 to 60g of dioscorea, 30 to 60g of tangerine peel and 30 to 60g of crataegus. The composition is prepared according to the cause of diarrhea of weaned piglets and the principles of rectifying the spleen, harmonizing the stomach, supplementing qi and drying dampness and has the effects of regulating the microecological environment of intestinal tracts, enhancing the immunity, preventing and treating the diarrhea of the weaned piglets, along with low addition ratio in the daily ration, safety and no residue.
Description
Technical field
The present invention relates to the Chinese medicine compound compositions, specifically a kind of treatment diarrhea of weaned piglets Chinese medicine compound compositions.
Background technology
Piglet diarrhea all has the weightening finish of piglet survival ratio and later stage and has a strong impact on, and becomes the important diseases of restriction pig industry development.It is very common that 1 week of wean back, the diarrhoea phenomenon took place, and mortality rate often reaches 10%-20%, and high reaches more than 40%.The antibiosis class drug development of treatment piglet diarrhoea is rapid, and be widely used in veterinary clinic, and the dosage of use is also increasing, and Resistant strain also increases gradually, cause many unfavorable factors to this disease of clinical treatment, the food safety that causes, environmental pollution and drug resistance problem receive publicity day by day.Many developed countries successively ban use of antibiotic as feed additive, utilize the green barrier reduction simultaneously even stop the import meat from China, bring about great losses for China's meat products outlet.And the contained active substance of Chinese medicine compound has many target spots, can the enhancing human body immunity function, improve animal anti-stress, anti-disease ability, and improve breeding performonce fo animals, and have low-residual, be difficult for producing advantages such as drug resistance.Therefore development treatment diarrhea of weaned piglets Chinese medicine compound has great importance to the pig industry of China.
In recent years, China's piglet diarrhea is very general, is one of difficult problem of current puzzlement pig industry development.In the modernization Swine Production, usually take the way of early weaning to shorten the age of sucking of sow, improve the fertility performance of sow; But early weaning often brings a series of harmful effects to piglet, and it is very common wherein 1 week of wean back the diarrhoea phenomenon to take place.According to investigations, piglet accounts for 39.8% of the dead sum of piglet because of the death of suffering from diarrhoea.Piglet below 30 kilograms, average of the whole year sickness rate 46.5%, mortality rate 10.30%, the economic loss number that estimation China causes every year thus is with hundred million yuan.The generation of this disease is popular except that the direct death that causes pig, and also remote-effects become the important restraining factors that influence the economic benefit of raising pigs to the growth promoter of the pig of recovering.In recent years, the antibiosis class drug development of treatment piglet diarrhoea is rapid, and be widely used in veterinary clinic, the dosage that uses is also increasing, Resistant strain also increases gradually, cause many unfavorable factors to this disease of clinical treatment, the food safety that causes, environmental pollution and drug resistance problem receive publicity day by day.Many developed countries successively ban use of antibiotic as feed additive, utilize the green barrier reduction simultaneously even stop the import meat from China, bring about great losses for China's meat products outlet.Cause the reason more complicated of diarrhea of weaned piglets, mainly comprise nutrition physiology characteristics (digestive function is unsound, the influence of ablactation stress, external environment) and the disease factor (infection of antibacterial and virus) of piglet.Therefore, exploitation have wide spectrum, antimicrbial power strong, be difficult for producing drug resistance, medicine that toxic and side effects is little, being that veterinary circle is anxious need to wait the problem that solves.And the product that the Chinese herbal medicine distinctive Chinese medical theory that is China combines with practice, its aboundresources, with a long history, its effect and safety have been approved by people, are a big focus of international research in recent years as animal feed additive.Its contained active substance has many target spots, can the enhancing human body immunity function, improve animal anti-stress, anti-disease ability, and improve breeding performonce fo animals, and have low-residual, be difficult for producing advantages such as drug resistance.Chinese veterinarian's theory is thought the many and being invaded by exogenous pathogen of piglet diarrhea, and internal damage caused by infantile dyspepsia and weakness of the spleen and stomach are in close relations, and feeding and management is not good in addition, and it is not normal to cause transformation and transportation of the spleen and stomach, indigestion, clear QI being mixed up with turbid QI and having loose bowels.According to the principle that the dialectical opinion of Chinese veterinarian is controlled, " the spleen strengthening and damp drying " is the cardinal principle of treatment piglet diarrhea.According to traditional Chinese veterinary medicine theory and practice experience, piglet diarrhea is carried out determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs during treatment, from aspect prescriptions such as invigorating the spleen and replenishing QI, strengthening the spleen and nourishing the stomach, heat-clearing and toxic substances removing, dampness-eliminating and dysentery-stoppings.Piglet is in the period that growth promoter is exceedingly fast, and internal organs are tender and lovely, the spleen tending to insufficiency usually.Though cold and heat, new of a specified duration having loose bowels, all disease of visible weakness of the spleen and stomach.Eliminating pathogenic factor for supporting vital QI, make taste strong and, the then digestion of feedstuff, absorption and precise and tiny defeated cloth are normal, diarrhoea is from ending.
Summary of the invention
A kind of treatment diarrhea of weaned piglets Chinese medicine compound compositions of providing at the deficiencies in the prior art is provided, and said composition has treatment and preventive effect to diarrhea of weaned piglets, reduces the loss that pig industry causes because of this symptom greatly.
The object of the present invention is achieved like this:
A kind of treatment diarrhea of weaned piglets Chinese medicine compound compositions, said composition is to be mixed with distilled water by following traditional Chinese medicine raw, and decoction, filtering and impurity removing, merging filtrate, concentrating under reduced pressure, drying make, and raw material of Chinese medicine consists of:
Radix Codonopsis 50～70 grams, the Radix Astragali 50～70 grams, Radix Glycyrrhizae (processing) 50～70 grams, the Rhizoma Atractylodis Macrocephalae 30～50 grams, Poria 20～40 grams, Rhizoma Zingiberis 20～40 grams, Rhizoma Dioscoreae 30～60 grams, Pericarpium Citri Reticulatae 30～60 grams, Fructus Crataegi 30～60 grams.
The preparation method of above-mentioned composition is with Radix Codonopsis 50～70 grams, the Radix Astragali 50～70 grams, Radix Glycyrrhizae (processing) 50～70 grams, the Rhizoma Atractylodis Macrocephalae 30～50 grams, Poria 20～40 grams, Rhizoma Zingiberis 20～40 grams, Rhizoma Dioscoreae 30～60 grams, Pericarpium Citri Reticulatae 30～60 grams, Fructus Crataegi 30～60 grams and the mixed of distilled water by weight 1: 3, decoct 3 times, each 30 minutes, filtering and impurity removing then, merging filtrate, concentrating under reduced pressure, drying makes.
The present invention is the cause of disease according to diarrhea of weaned piglets, and with the principle prescription of reason spleen stomach function regulating, QI invigorating, dampness, this compound recipe has the effect of conditioning intestine of young pigs microecological environment, enhancing immunity, has significant effect for prevention and treatment diarrhea of weaned piglets; Adding proportion is low in the daily ration, safe noresidue.
The specific embodiment
Piglet diarrhea is meant that the piglet at 1～3 monthly age is the mass-sending disease of cardinal symptom with the dysentery, and especially sickness rate is quite high in the 10～15d of wean back, has brought very big loss to pig industry.
Embodiment 1
Radix Codonopsis 60 grams, the Radix Astragali 60 grams, Radix Glycyrrhizae (processing) 60 grams, the Rhizoma Atractylodis Macrocephalae 45 grams, Poria 30, Rhizoma Zingiberis 30 grams, Rhizoma Dioscoreae 50, Pericarpium Citri Reticulatae 50, Fructus Crataegi 50 grams and the mixed of distilled water by weight 1: 3, decoct 3 times, each 30 minutes, filtering and impurity removing then, merging filtrate, concentrating under reduced pressure dryly must be treated diarrhea of weaned piglets Chinese medicine compound compositions.
1. the test of prevention diarrhea of weaned piglets
The test contrast
1.1 test drug
Above-mentioned Chinese medicine compound compositions.
Citric acid: the 25kg/ bag (lot number: 20090609), produce by certain Citric Acid Plant.
1.2 experimental animal
Close and the healthy ablactational baby pig of 28 age in days body weight.
1.3 EXPERIMENTAL DESIGN
60 ablactational baby pig are divided into two groups, prevent 30 of Chinese medicine compound compositions groups, 30 of citric acid groups.Chinese medicine compound compositions group is weaned piglet and was begun to add 0.05% Chinese medicine compound compositions every day in diet the same day, adds continuously 15 days; The citric acid group is added 0.5% citric acid every day in diet, added continuously 15 days.
1.4 test site
Certain pig farm.
1.5 test index
The prevention effective percentage accounts for the percentage rate of a prevention number for effective number of prevention.A morbidity number is meant that prophylactic finishes the morbidity number in the 13d of back; Prevent effective number to be meant that prophylactic finishes a number of no disease symptoms in the 3d of back, during prophylactic, existing symptom lists the row for the treatment of a number in, does not list a prevention number in.
1.6 result
Table 1 diarrhea of weaned piglets prophylactic tria result
By table 1 as seen, Chinese medicine compound compositions group is 90% to the prevention rate of piglet diarrhea, and the citric acid group is 86.7%.
Embodiment 2
Radix Codonopsis 60 grams, the Radix Astragali 60 grams, Radix Glycyrrhizae (processing) 60 grams, the Rhizoma Atractylodis Macrocephalae 45 grams, Poria 30, Rhizoma Zingiberis 30 grams, Rhizoma Dioscoreae 50 grams, Pericarpium Citri Reticulatae 50 grams, Fructus Crataegi 50 grams and distilled water are after 1: 3 mixed, decoct 3 times, each 30 minutes, filtering and impurity removing then, merging filtrate, concentrating under reduced pressure, dryly must treat diarrhea of weaned piglets Chinese medicine compound compositions, before the use, its compositions is mixed with the solution of 0.11g/ml with aquesterilisa.
2. the test of control diarrhea of weaned piglets
2.1 test drug
Above-mentioned Chinese medicine compound composition solution.
Gentamycin: 2ml/ props up that (lot number: 20090621), Tianjin pharmaceutcal corporation, Ltd produces.
2.2 experimental animal
In swinery, select to suffer from 120 of diarrheal ablactational baby pig.
2.3 EXPERIMENTAL DESIGN
Suffer from the diarrheal ablactational baby pig for 120 and be divided into two groups, 60 every group, use Chinese medicine compound compositions and gentamycin to treat respectively.The Chinese medicine compound composition solution is oral, every of every day 2 times, each 2ml; The gentamycin intramuscular injection, every of every day 2 times, each 2ml.
2.4 testing index
Cure rate accounts for the percentage rate for the treatment of a number for curing a number.A healing number refers to the interior transference cure of medication 3d or alleviates; The interior symptom of 3d did not alleviate or death after a number of failing to respond to any medical treatment referred to medication.
2.5 test site
Certain pig farm.
2.6 result
Table 2 diarrhea of weaned piglets therapeutic test result
As seen from Table 2, the cure rate of gentamycin group is 90%, Chinese drug-treated group 91.7%.
Claims (2)
1. a treatment diarrhea of weaned piglets Chinese medicine compound compositions is characterized in that said composition is to be mixed with distilled water by following traditional Chinese medicine raw, and decoction, filtering and impurity removing, merging filtrate, concentrating under reduced pressure, drying make, and raw material of Chinese medicine consists of:
Radix Codonopsis 50～70 grams, the Radix Astragali 50～70 grams, Radix Glycyrrhizae (processing) 50～70 grams, the Rhizoma Atractylodis Macrocephalae 30～50 grams, Poria 20～40 grams, Rhizoma Zingiberis 20～40 grams, Rhizoma Dioscoreae 30～60 grams, Pericarpium Citri Reticulatae 30～60 grams, Fructus Crataegi 30～60 grams.
2. Chinese medicine compound compositions according to claim 1, the preparation method that it is characterized in that said composition are with Radix Codonopsis 50～70 grams, the Radix Astragali 50～70 grams, Radix Glycyrrhizae (processing) 50～70 grams, the Rhizoma Atractylodis Macrocephalae 30～50 grams, Poria 20～40 grams, Rhizoma Zingiberis 20～40 grams, Rhizoma Dioscoreae 30～60 grams, Pericarpium Citri Reticulatae 30～60 grams, Fructus Crataegi 30～60 grams and the mixed of distilled water by weight 1: 3 decoct each 30 minutes 3 times, filtering and impurity removing then, merging filtrate, concentrating under reduced pressure, drying makes.
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| CN103316272A (en) * | 2012-03-21 | 2013-09-25 | 汕头市畜宝生物科技有限公司 | Chinese medicinal composition for preventing swine diarrhea |
| CN103445001A (en) * | 2013-09-22 | 2013-12-18 | 金陵科技学院 | Traditional Chinese medicine feed additive capable of improving growth and function development of animal gastrointestinal tract, preparing method thereof and application thereof |
| CN103495151A (en) * | 2013-09-30 | 2014-01-08 | 河南亚卫动物药业有限公司 | Traditional Chinese medicine composition for treating pig cold diarrhea and preparation method thereof |
| CN103520683A (en) * | 2013-10-21 | 2014-01-22 | 曹远东 | Spleen-tonifying anti-diarrheic granule for piglets and preparation method of granule |
| CN103721227A (en) * | 2013-12-20 | 2014-04-16 | 河北科星药业有限公司 | Traditional Chinese medicinal composition for preventing spleen and stomach deficiency type diarrhea for weaned piglets |
| CN104436142A (en) * | 2014-12-19 | 2015-03-25 | 何子双 | Traditional Chinese medicine composition for treating porcine epizootic diarrhea |
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| CN104799109A (en) * | 2015-05-11 | 2015-07-29 | 中国科学院东北地理与农业生态研究所 | Feed additive capable of reducing diarrhea rate of piglets |
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| CN106668388A (en) * | 2016-11-18 | 2017-05-17 | 安徽禾泉农庄生态农业有限公司 | Method for treating diarrhea of pregnant ewes |
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