CN103202900B - Traditional Chinese medicine feed additive for preventing and curing livestock and poultry diarrhea - Google Patents
Traditional Chinese medicine feed additive for preventing and curing livestock and poultry diarrhea Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicine feed additives, and in particular relates to a traditional Chinese medicine health-care feed additive for preventing and curing livestock and poultry diarrhea. The traditional Chinese medicine feed additive mainly comprises the following traditional Chinese medicinal materials in parts by weight: 10-20 parts of coptis chinensis, 15-20 parts of jasmine, 10-20 parts of root of common peony, 15-25 parts of dandelion and 10-15 parts of astragalus mongholicus. The traditional Chinese medicine feed additive provided by the invention has the efficacies of clearing away heat, purging pathogenic fire, detoxifying and the like, has obvious effects of preventing and curing livestock and poultry diarrhea, also can effectively prevent milk resistance, medicament residues and food safety issues, and is suitable for being popularized in animal production.
Description
Technical field
The invention belongs to veterinary drug technical field, particularly a kind of Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea.
Background technology
Along with urban and rural residents of China improve constantly livestock and poultry product quality requirement, as required product safety, green, drug residue free, nuisanceless etc.For meeting the vigorous market demand; the livestock and poultry breeding industry of China is constantly developed; breeding environment constantly worsens simultaneously; disease incident is more and more higher; a large amount of medicines adds causes animal products quality security problem to become increasingly conspicuous, and also brings the public to the trust crisis of animal products quality safety thus.Especially the event such as numerous media unit exposure such as CCTV1, CCTV13 and Focus fast-growing chickens in 2012 and false veterinary drug causes great disturbance in the industry, and medicine is easily residual is simultaneously the key factor affecting the animal products safety such as meat, egg, milk.Human body often takes in the left drugs such as the antibiotic of low dosage, can accumulate in vivo gradually and cause various organ generation pathology, produce allergy, allergic reaction, immunosupress etc., final harm humans is healthy, and the development that will continue to China's animal husbandry science causes and has a strong impact on.
Because cause the reason of diarrhoea a lot (as virus infections, bacteriological infection, water pollution, feed mold, environmental factor, the many factors such as temperature great change), cause treatment difficulty to strengthen, the antimicrobial at present for controlling livestock and poultry diarrhea has kind more than 200, and wherein beta-lactam antibiotic is as Amoxicillin, ampicillin, Ceftiofurs etc. are the common drugs in pig fowl preventing and treating bacterial diseases of young, but due to Long-Time Service, livestock and poultry Escherichia coli, the resistant rate of salmonella etc. is very high, and its curative effect significantly declines even invalid, and drug-fast bacteria is the trend of multidrug resistant and crossing drug resistant, and namely drug-fast bacteria is to FQNS, aminoglycoside, Florfenicol, compound sulfonamide medicine is also in resistance, add clinical in a large amount of abuse of antibiotics, even use human drugs, cause drug resistance problems day by day serious, result for the treatment of is day by day not remarkable, increase the weight of the difficulty of antibiotic research and development, be meanwhile used for the treatment of virus and cause the chemicals of diarrhoea as far back as U.S. FDA in 2006, amantadine is forbidden in the dispatch of the Ministry of Agriculture of China, Rimantadine, ACV, morpholine (two) guanidine (moroxydine), the chemical antiviral medicines such as Ribavirin, these measures cause cause of disease to produce the serious resistance to the action of a drug to these medicines, the more important thing is that these medicines easily remain, and harm humans is healthy, cause livestock and poultry and fur-bearing animal diarrhoea prevention and therapy medicine to occur blank.At present, diarrhoea still lacks the Chinese herbal feed additive of good prevention and therapy clinically, therefore urgently develops a kind of Chinese herbal feed additive of safe and reliable prevention and therapy diarrhoea to meet the demand of actual production.
Summary of the invention
The object of the present invention is to provide a kind of Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea.
The technical solution used in the present invention is as follows:
A Chinese herbal feed additive for prevention and therapy livestock and poultry diarrhea, the Chinese medicine primarily of following weight portion forms: coptis 10-20 part, cape jasmine 15-20 part, radix paeoniae rubrathe 10-20 part, dandelion 15-25 part, Radix Astragali 10-15 part.
Further, with parts by weight, also comprise: golden cypress 10-15 part, mother chrysanthemum 10-15 part, selfheal 15-20 part, thick wood-fern rhizome 10-15 part, lophatherum gracile 10-15 part, moutan bark 10-15 part, cordate houttuynia 10-20 part, root of large-flowered skullcap 10-20 part.
Belong to heat symptoms caused by an exopathgen from the dialectical diarrhoea of Chinese veterinarian's angle and be full of three burnt, the real hot or damp and hot illnesss of internal organs.Therefore with the clear purge the sthenic heart-fire of the coptis in side, the fire of clear middle Jiao that holds concurrently is main ingredient, and cape jasmine rushes down clearly the fire of three Jiao, diuresis, heat conduction is descending, the clear part of the body cavity above the diaphragm housing the heart and lungs lung-fire of the root of large-flowered skullcap, golden cypress rushes down the fire of part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels liver kidney, selfheal, dandelion, mother chrysanthemum, thick wood-fern rhizome, moutan bark, cordate houttuynia, lophatherum gracile are clearing heat and detoxicating etc. is adjuvant, radix paeoniae rubrathe clearing heat and cooling blood, promoting blood circulation to remove blood stasis, dysmenorrhoea analgesia is adjutant, the righting of Radix Astragali benefit gas, myogenic, the removing toxic substances of holder sore is for making medicine.All medicines share, and play the effect of clearing heat-fire, removing toxic substances, antibacterial, anti-inflammatory altogether, have antiviral functions.
This Chinese herb feed additive, according to the dialectical theory of Chinese veterinarian, not only can prevent livestock and poultry diarrhea, and result for the treatment of is remarkable, effective equally to fur-bearing animal.As prevented the diseases such as animal diarrhea such as chicken, duck, goose, quail, ox, sheep, donkey, camel, fox, racoon dog, ermine, rabbit all to have good curative effect, total effective rate is more than 96%.If when treating, total effective rate is more than 97%.
Chinese herbal feed additive of the present invention, regulates using dosage can prevent or treat the diarrhoea of livestock and poultry and fur-bearing animal significantly, and during as prevention, general addition is the 0.4-0.6% of forage volume; If treatment diarrhoea, using dosage is 0.5-1.5%.During use, after said medicine can being pulverized, cross 300 mesh sieves, obtain powder.Scale livestock farming can adopt spice mixed feeding method, and raising family scattered both can spice mixed feeding, and also powder decocting can be got juice drinking-water, large domestic animal also can adopt and gavage.Chinese herb feed additive of the present invention is pure tcm product, various formulation can be made as powder, oral liquid, granule, tablet, pill, paste etc., can effectively avoid anti-milk, medicament residue and food-safety problem, be suitable for promoting in husbandry sector.
Detailed description of the invention
With specific embodiment, technical scheme of the present invention is described below, but protection scope of the present invention is not limited thereto:
Embodiment 1
The feed addictive of control livestock and poultry diarrhea, it is composed as follows: coptis 15g, cape jasmine 17.5g, radix paeoniae rubrathe 15g, dandelion 20g, Radix Astragali 12.5g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 2
The feed addictive of control livestock and poultry diarrhea, it is composed as follows: coptis 10g, cape jasmine 15g, radix paeoniae rubrathe 10g, dandelion 15g, Radix Astragali 10g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 3
The feed addictive of control livestock and poultry diarrhea, it is composed as follows: coptis 20g, cape jasmine 20g, radix paeoniae rubrathe 20g, dandelion 25g, Radix Astragali 15g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 4
The feed addictive of control livestock and poultry diarrhea, it is composed as follows:
Coptis 15g, cape jasmine 17.5g, radix paeoniae rubrathe 15g, dandelion 20g, Radix Astragali 12.5g, golden cypress 12.5g, mother chrysanthemum 12.5g, selfheal 17.5g, thick wood-fern rhizome 12.5g, lophatherum gracile 12.5g, moutan bark 12.5g, cordate houttuynia 15g, root of large-flowered skullcap 15g.
All medicine pulverizations cross 300 mesh sieves, are a powder.
Embodiment 5
The feed addictive of control livestock and poultry diarrhea, it is composed as follows:
Coptis 10g, cape jasmine 15g, radix paeoniae rubrathe 10g, dandelion 15g, Radix Astragali 10g, golden cypress 10g, mother chrysanthemum 10g, selfheal 15g, thick wood-fern rhizome 10g, lophatherum gracile 10g, moutan bark 10g, cordate houttuynia 10g, root of large-flowered skullcap 10g.
All medicine pulverizations cross 300 mesh sieves, are a powder.
Embodiment 6
The feed addictive of control livestock and poultry diarrhea, it is composed as follows:
Coptis 20g, cape jasmine 20g, radix paeoniae rubrathe 20g, dandelion 25g, Radix Astragali 15g, golden cypress 15g, mother chrysanthemum 15g, selfheal 20g, thick wood-fern rhizome 15g, lophatherum gracile 15g, moutan bark 15g, cordate houttuynia 20g, root of large-flowered skullcap 20g.
All medicine pulverizations cross 300 mesh sieves, are a powder.
Effect:
Embodiment 1 additive spice is taken orally: during treatment, the large domestic animal such as ox, horse and camel: 150-300g/ head; Pig, sheep: 50-100g/ head, only, only, bird: 1-3g/ only, adds up curative effect after being used in conjunction 5 days to rabbit: 6-12g/ to fox, racoon dog, ermine: 15-30g/.Preventive dose reduces by half.
Efficacy determination: during prevention, protective rate is considered as effectively more than 96%.During treatment, take medicine 5, symptom of diarrhea is eliminated, and in 7 days not repeatedly, is considered as curing; In 10 days, without symptom of diarrhea, be considered as effectively, otherwise be considered as invalid.
Effect refers to table 1(prevention) and table 2(treatment).
Table 1
Table 2
| Poultry kind | Morbidity (head, only) | Cure (head, only) | Cure rate | Effectively (head, only) number | Efficient |
| ? | Number | Number | ? | ? | ? |
| Pig | 1178 | 1087 | 92.3% | 1143 | 97.0% |
| Ox | 82 | 75 | 91.5% | 79 | 96.3% |
| Horse | 13 | 11 | 84.6% | 13 | 100.0% |
| Sheep | 26 | 23 | 88.5% | 25 | 96.2% |
| Fox | 67 | 62 | 92.5% | 65 | 97.0% |
| Racoon dog | 72 | 66 | 91.7% | 72 | 100% |
| Ermine | 91 | 84 | 92.3% | 88 | 96.7% |
| Chicken | 227631 | 212339 | 93.3% | 220807 | 97.0% |
| Duck | 67359 | 63115 | 93.7% | 66146 | 98.2% |
| Goose | 22087 | 20783 | 94.1% | 21557 | 97.6% |
| Quail | 16984 | 15693 | 92.4% | 16508 | 97.2% |
Embodiment 4 additive spice is taken orally: during treatment, the large domestic animal such as ox, horse and camel: 150-300g/ head; Pig, sheep: 50-100g/ head, only, only, bird: 1-3g/ only, or according to forage volume 0.5-1.5% spice mixed feeding, adds up curative effect after being used in conjunction 5 days to rabbit: 6-12g/ to fox, racoon dog, ermine: 15-30g/.Preventive dose reduces by half.
Efficacy determination is with embodiment 1 additive.The results detailed in Table 3(prevention) and table 4(treatment).
Table 3
Table 4
Concrete case 1
In January, 2010,10000 Sanhuang broilers that Zhumadian Lee raises, randomly draw 500 and be divided into test group and control group, except conveniently raising, immunity inoculation, sterilization etc., the Chinese medicine composition of Example 1 is pulverized, and crosses 300 mesh sieves, and test group is added into feed according to 0.5% ratio and makes particle after mixing, add from 12 ages in days, until deliver for sale.
Period, control group occurred that the chicken of diarrhoea death amounts to 26, the death rate 10.4% except natural death; Test group because of dead chicken 7 of suffering from diarrhoea, the death rate 2.8%.
Concrete case 2
In March, 2010, the pig farm of Zhumadian Wang extracts 6 nests out at random with the piglet 73 of age in days with pig house, test group 36, control group 37, test number of days 20 days, period test group and control group except conveniently yard feeding pattern raisings, immunity inoculation, sterilization etc., the Chinese medicine composition pulverizing of Example 3, cross 300 mesh sieves, test group, according to 30g/ head, makes an addition to feed and makes particle after mixing, weaning first 3 days, bring into use, be used in conjunction 7 days.
There is not diarrhoea in period test group 36 piglets, efficient 100%; 6 are had to occur diarrhoea, the incidence of disease 16.21% in control group 37 piglets.According to 50g/ head after morbidity, decocting powder is got juice and is gavaged, and once a day, is used in conjunction 5, and simultaneously fluid infusion salt is used in conjunction 3 days, and wherein 1 serious sick pig adopts mequindox injection intramuscular injection to carry out treatment 3 days, and after 5 days, sick pig is all fully recovered.
Concrete case 3
In June, 2010,12000 quails that suburb, Jiaozhuo Zhu raises, randomly draw 600, are divided into test group and control group, each 300, two groups of conveniently raising, immunity inoculation, sterilizations etc. in unified house.
The Chinese medicine composition of Example 4 is pulverized, and crosses 300 mesh sieves, and test group is added into feed according to 0.4% ratio and makes particle, until deliver for sale from 5 ages in days after mixing.Period, control group occurred that the quail of diarrhoea death amounts to 29, the death rate 9.67% except natural death; Test group because of dead quail 7 of suffering from diarrhoea, the death rate 2.33%.
Concrete case 4
In May, 2011,4000 laying hens that Zhongmou County Wang raises were at 135 days, and part laying hen occurs that ight soil is thin in water sample, occasionally had yellow, white, green ight soil, body is become thin, and severe growth is bad, and cockscomb turns white, laying rate fluctuates, and eggshell color turns white, and indivedual chicken occurs dead; Pathological change is mainly manifested on enteron aisle, and intestinal mucosa is congested, hemorrhage, come off, and intestines wall is thinning, and cloaca is hemorrhage, interior just like watery yellow-white ight soil etc.
The Chinese medicine composition of Example 5 is pulverized, is crossed 300 mesh sieves and mix; Get this powder by 0.8% of material feeding amount to boil water, liquid is drunk water, dregs of a decoction spice, and after being used in conjunction 5 days, symptom disappears substantially, does not occur Relapse rate in 7 days, and disease must heal, and during medication, none example is dead.
Concrete case 5
In March, 2010, raise piglet 360 in a pig house of Zhumadian Chen, piglet is suffered from diarrhoea suddenly, discharge milky or linen pulpous state, pasty state stickiness ight soil, stench, sometimes with bubble or the trace of blood, then sick pig occurs that spirit is tired, and by hair slightly disorderly, body surface is unglazed, anorexia, weakness of limbs, walking is unstable or sleeping ground is difficult rises, ight soil is canescence stench, slack anus, fecal incontinence, become thin, dewater, indivedual pig extremely feeble and dead, case fatality rate 3.61%.Pathological change is that sick dead pig corpse is become thin, and mucous membrane is pale, anus and around faecal contamination, and intestinal mucosa is catarrhal inflammation, and intestines wall is thinning, has milky or canescence pasty state or ointment shape content, lymphonodi mesenterici mild swelling etc. in colon.Through clinical symptoms, pathological change and laboratory diagnosis, be diagnosed as the white scour of piglet.
The Chinese medicine composition of Example 6 is pulverized, cross 300 mesh sieves, test group is according to 50g/ head, and decocting is got juice and gavaged, once a day, serve on 5, dregs of a decoction spice, the salt of fluid infusion simultaneously drinking-water is used in conjunction 3 days, after 5 days, symptom disappears substantially, do not occur Relapse rate in 7 days, recovery from illness, during medication, none piglet is dead.
Concrete case 6
In November, 2010, there is poor appetite in piglet about Changzhi City Zhao buys 180 60 ages in days from other places, and spirit is depressed, vomiting and mucus diarrhoea, and between ight soil or have blood or come to mucous membrane tissue fragment etc., case fatality rate is 8.3%.Pathological change is based on enteron aisle.Small intestinal mucosa and mesenterium are congested, hemorrhage, dilatation of intestine, in be full of yellow liquid, intestinal villi shortens, and severe one Villus atrophy, even disappears; Colorectal mucosa generation Catarrhal, hemorrhagic enteritis, colon and the swelling of caecum mucous membrane, gauffer is obvious, above with mucus, clot and fibrinous exudate etc.Swine dysentery and epidemic diarrhea mixed infection is diagnosed as through clinical symptoms, pathological change and laboratory diagnosis.
The Chinese medicine composition of Example 2 is pulverized, cross 300 mesh sieves, test group is according to 75g/ head, and decocting is got juice and gavaged, once a day, serve on 5, dregs of a decoction spice, the salt of fluid infusion simultaneously drinking-water is used in conjunction 3 days, and piglet serious individually coordinates berberine sulphate parenteral solution, mequindox injection and interferon intramuscular injection, every day 1 time, be used in conjunction 3 days.After 5 days, symptom of diarrhea disappears substantially, does not occur Relapse rate in 7 days, recovery from illness, and during medication, none piglet is dead.
Above-described embodiment is the preferred embodiment of the present invention, but embodiments of the present invention are not restricted to the described embodiments, and the change that other any the present invention of not deviating from does all should be equivalent substitute mode, is included within protection scope of the present invention.
Claims (1)
1. the Chinese herbal feed additive of a prevention and therapy livestock and poultry diarrhea, it is characterized in that, be made up of the Chinese medicine of following weight portion: coptis 10-20 part, cape jasmine 15-20 part, radix paeoniae rubrathe 10-20 part, dandelion 15-25 part, Radix Astragali 10-15 part, golden cypress 10-15 part, mother chrysanthemum 10-15 part, selfheal 15-20 part, thick wood-fern rhizome 10-15 part, lophatherum gracile 10-15 part, moutan bark 10-15 part, cordate houttuynia 10-20 part, root of large-flowered skullcap 10-20 part.
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| CN101926411A (en) * | 2010-09-14 | 2010-12-29 | 丽水市林业科学研究院 | Heartleaf houttuynia herb livestock and poultry feed additive and preparation method thereof |
| CN102038082A (en) * | 2010-09-02 | 2011-05-04 | 吴艳霞 | Traditional Chinese medicinal feed additive for treating dysentery and diarrhea of livestock and poultry |
| CN102232467A (en) * | 2011-04-15 | 2011-11-09 | 北京康华远景科技有限公司 | Livestock and poultry anti-diarrheal feed additive and preparation method thereof |
| CN102379962A (en) * | 2010-09-03 | 2012-03-21 | 山东绿源新食品有限公司 | Traditional Chinese medicine combination for healthcare and treatment of livestock |
| CN102429967A (en) * | 2011-12-29 | 2012-05-02 | 甘肃农业大学 | Traditional Chinese medicine composition for preventing and treating bacterial diarrhea of livestock and poultry and application thereof |
| CN102640864A (en) * | 2012-02-23 | 2012-08-22 | 上海交通大学 | Chinese medicinal herb feed additive for improving immunity of chickens and preventing diarrhea and using method for additive |
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| CN102038082A (en) * | 2010-09-02 | 2011-05-04 | 吴艳霞 | Traditional Chinese medicinal feed additive for treating dysentery and diarrhea of livestock and poultry |
| CN102379962A (en) * | 2010-09-03 | 2012-03-21 | 山东绿源新食品有限公司 | Traditional Chinese medicine combination for healthcare and treatment of livestock |
| CN101926411A (en) * | 2010-09-14 | 2010-12-29 | 丽水市林业科学研究院 | Heartleaf houttuynia herb livestock and poultry feed additive and preparation method thereof |
| CN102232467A (en) * | 2011-04-15 | 2011-11-09 | 北京康华远景科技有限公司 | Livestock and poultry anti-diarrheal feed additive and preparation method thereof |
| CN102429967A (en) * | 2011-12-29 | 2012-05-02 | 甘肃农业大学 | Traditional Chinese medicine composition for preventing and treating bacterial diarrhea of livestock and poultry and application thereof |
| CN102640864A (en) * | 2012-02-23 | 2012-08-22 | 上海交通大学 | Chinese medicinal herb feed additive for improving immunity of chickens and preventing diarrhea and using method for additive |
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