CN103006916A - Pure traditional Chinese medicine recipe for curing various animal diarrhoeal diseases and preparation method of pure traditional Chinese medicine recipe - Google Patents
Pure traditional Chinese medicine recipe for curing various animal diarrhoeal diseases and preparation method of pure traditional Chinese medicine recipe Download PDFInfo
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- CN103006916A CN103006916A CN2012105250540A CN201210525054A CN103006916A CN 103006916 A CN103006916 A CN 103006916A CN 2012105250540 A CN2012105250540 A CN 2012105250540A CN 201210525054 A CN201210525054 A CN 201210525054A CN 103006916 A CN103006916 A CN 103006916A
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Abstract
The invention discloses a pure traditional Chinese medicine recipe for curing various animal diarrhoeal diseases and a preparation method of the pure traditional Chinese medicine recipe. The pure traditional Chinese medicine recipe comprises the following ingredients: 1 g of white paeony root, 1 g of atractylis ovata, 1 g of Chinese pulsatilla root, 1 g of rhizoma atractylodis, 2 g of dried orange peel, 1 g of folium isatidis, 1 g of cortex phellodendri, 0.75 g of fructus forsythiae, 3 g of dandelion, 1.5 g of ash bark, 5 g of garden burnet, 1 g of pomegranate rind and 1 g of tuckahoe. The recipe has an effect on curing various animal diarrhoeal diseases such as piglet's yellow-white dysentery, epidemic diarrhea and transmissible gastroenteritis; the preparation method is simple and convenient to operate; and suitability for popularization and application is obtained.
Description
Technical field
The invention belongs to medical technical field, relate to a kind of pure Chinese medicine formula for the treatment of various animal diarrhoeal diseasess and preparation method thereof.
Background technology
People often and epidemic diarrhea sick transmissible gastroenteritis of swine call " pig winter have loose bowels disease ", also title " pig winter dysentery ".The pig at various ages all can fall ill, and be onset peak period March November in the first year to next year.Sick pig watery diarrhea is radial discharge sometimes, and feces is yellow, white, canescence or green, and piglets often dies because the dehydration of acutely having loose bowels too much causes death.Because the pig winter dysentery belongs to viral acute infectious disease, and normal and several cause of disease mixed infections, clinical curative effect with antibacterial drug therapy is not ideal enough; Later recover appetite though most of sick pigs (mainly being big-and-middle pig) are anti-, body weight from falling ill to recovering generally at 30～40 days, causes serious economic loss to pig industry.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of pure Chinese medicine formula for the treatment of various animal diarrhoeal diseasess and preparation method thereof, this prescription has curative effect height, instant effect, dispensing conveniently, cheap, difficult generation drug resistance, the characteristics that toxic and side effects is little, its preparation method is simple and easy to do, is fit to apply.
Its technical scheme is as follows:
A kind of pure Chinese medicine formula for the treatment of various animal diarrhoeal diseasess comprises following composition: Radix Paeoniae Alba 1g, Rhizoma Atractylodis Macrocephalae 1g, Radix Pulsatillae 1g, Rhizoma Atractylodis 1g, Pericarpium Citri Reticulatae 2g, Folium Isatidis 1g, Cortex Phellodendri 1g, Fructus Forsythiae 0.75g, Herba Taraxaci 3g, Cortex Fraxini 1.5g, Radix Sanguisorbae 5g, Pericarpium Granati 1g, Poria 1g.
A kind of preparation method for the treatment of the pure Chinese medicine of various animal diarrhoeal diseasess takes by weighing each constituent according to prescription of the present invention, puts oven dry under 65 ℃ in the baking oven, pulverizes to be smalls, crosses 40 mesh sieves, and mix homogeneously is deposited in aeration-drying place after the packing.
Beneficial effect of the present invention: the present invention treats the pure Chinese medicine formula of various animal diarrhoeal diseasess, effect with invigorating the spleen and benefiting QI, removing dampness to restore normal function of the stomach, dyspepsia and intestinal stasis relieving, clearing away heat-fire, broad-spectrum antiseptic, energy enhancing human body immunity power, improve Animal stress reaction, adjustment gastrointestinal function.This Chinese medicine compound can improve the antibacterial ability of ablactational baby pig serum and improve leukocyte and lymphocytic content in the piglet blood; And improve piglet stomach, intestinal mucosa integrity, strengthen digestion power.This Chinese medicine compound can reduce the piglet diarrhea rate, and has certain dose-effect relationship, improves significantly with dosage rising effect.Treatment piglet Salmonella diarrhoea, cure rate reaches 100%; Effectively prevent ablactation piglet diarrhea totally 56 nests; The total cure rate for the treatment of diarrhoeal diseases pig, total effective rate, total relapse rate are respectively 82.76%, 93.53%, 3.88%; To the cure rate of the sick pig of winter dysentery up to 82.76%, relapse rate low (only being 3.88%).Cure rate and the relapse rate of the irritability diarrhoea that the treatment abrupt change of climate causes are respectively 96.77% and 2.78%.This Chinese medicine compound is described to the various diarrhoea diseases of animal, evident in efficacy such as yellow and white dysentery of piglet, epidemic diarrhea, transmissible gastroenteritis etc., its preparation method is easy and simple to handle, is fit to apply.
The specific embodiment
Below in conjunction with the specific embodiment technical scheme of the present invention is described in more detail.
A kind of pure Chinese medicine formula for the treatment of various animal diarrhoeal diseasess comprises following composition: Radix Paeoniae Alba 1g, Rhizoma Atractylodis Macrocephalae 1g, Radix Pulsatillae 1g, Rhizoma Atractylodis 1g, Pericarpium Citri Reticulatae 2g, Folium Isatidis 1g, Cortex Phellodendri 1g, Fructus Forsythiae 0.75g, Herba Taraxaci 3g, Cortex Fraxini 1.5g, Radix Sanguisorbae 5g, Pericarpium Granati 1g, Poria 1g.
A kind of preparation method for the treatment of the pure Chinese medicine of various animal diarrhoeal diseasess takes by weighing each constituent according to prescription of the present invention, puts oven dry under 65 ℃ in the baking oven, pulverizes to be smalls, crosses 40 mesh sieves, and mix homogeneously is deposited in aeration-drying place after the packing.
The experiment of beneficial effect of the present invention
For examination animal 11～December in 2006, Ya'an, Sichuan and peripheral county show as in various degree 232 of the sick pigs of winter dysentery (wherein 146 of ablactational baby pig, 86 of growth pigs) of diarrhoea (row's gruel shape, scattered paste shape, the stench feces of abnormal smells from the patient) clinically, be divided into I, II, III group by sick pig cultivating condition situation, 24 of I groups (farming pig farm, river), II organizes (family is raised in the suburbs, Yaan scattered) 80, and III organizes (Mingshan County is raised the family scattered) 128.
For examination bacteria Escherichia coli A, B and pig Salmonella, be separating obtained advantage/malignant bacteria in the sick swine excrement of clinical winter dysentery.
Method
The present invention prescription, is thrown by 0.2g/kg body weight spice and to be taken the present invention's powder of filling a prescription, 2 times/days to diarrhoea and still have the sick pig of certain appetite the therapeutic test of the sick pig of winter dysentery; Adopt the method that gavages administration to treat to not appetitive sick pig.
Efficacy determination medication feces on the 1st～2 is shaped, and color and luster normally is recovery from illness; The symptom of diarrhea alleviator is for taking a turn for the better; It is invalid not alleviating or adding severe one.Observe and record the disease pig and cure interior recurrence of rear 1 week.Daily management.The drug sensitive test paper disk method.The result judges: antibacterial circle diameter greater than 15mm as extremely sensitive; 10～15mm is medium sensitivity; Be drug resistance less than 10mm.
Results and analysis
The present invention's prescription sees Table 1 to the efficacy result of pig winter dysentery under the different breeding condition.
Table 1 prescription of the present invention is to the curative effect unit of pig winter dysentery under the different breeding condition: head (%)
By as seen from Table 1, prescription of the present invention is respectively 91.67%, 87.50%, 78.13% to the cure rate of I, II, III group pig winter dysentery; Effective percentage is respectively 100%, 96.25%, 90.63%; Relapse rate is respectively 0%, 2.50%, 5.47%.The present invention's prescription is respectively 82.76%, 93.53%, 3.88% to total cure rate, total effective rate, total relapse rate of pig winter dysentery.
2.2 prescription of the present invention sees Table 2 to the efficacy result of ablactational baby pig, growth pig winter dysentery.
Table 2 prescription of the present invention is to the efficacy result unit of ablactational baby pig, growth pig winter dysentery: head (%)
By as seen from Table 2, prescription of the present invention is respectively 88.37%, 96.51%, 2.33% to cure rate, effective percentage and the relapse rate of growth pig winter dysentery; Ablactational baby pig is 79.45%, 91.78%, 4.79%.The present invention's prescription is better than ablactational baby pig to the curative effect of growth pig winter dysentery.
Drug sensitive test the results are shown in Table 3.
Table 3.5 kind of common drug separates the antibacterial circle diameter (unit: mm) of dominant bacteria to the sick pig of winter dysentery
As can be seen from Table 3: test is with escherichia coli A, B, and pig Sha Shi bacillus is to the present invention fill a prescription decoct, long-acting terramycin and LIJUNJING medium sensitivity; Extremely sensitive to gentamycin, Ah fluorine's celestial being.The present invention fills a prescription decoct to test escherichia coli A, B, and the antibacterial circle diameter of pig Salmonella is respectively 12.10mm, 12.20mm and 12.18mm.
The present invention's prescription has good curative effect to the pig winter dysentery, and its clinical total cure rate reaches 82.76%, and total effective rate is up to 93.53%, and relapse rate is low only to be 3.88%.The present invention prescription all obviously is better than the Mingshan County to the clinical cure rate of farming pig farm, river pig winter dysentery and effective percentage and raises the family scattered, and this may to have the factors such as lagging facility, living environment health relevant with farming pig farm, river.
The present invention's prescription obviously is better than ablactational baby pig to the curative effect of growth pig winter dysentery.This may be few with the piglet subcutaneous fat, and cold hardiness is poor, and Development of Digestive Organs, Digest enzyme are still incomplete, and piglet immunological mechanism is unsound, and premunition is poor, and ablactation stress etc. is relevant.Therefore, in the control of ablactational baby pig winter dysentery, also should strengthen feeding and management, give the high-quality feed of good, the easy to digest absorption of nutrition, fast gaining; Note thermal insulation and cold resistance, take comprehensive preventive health measures.
Prescription of the present invention and long-acting terramycin, LIJUNJING are to test escherichia coli A, B, and pig Salmonella In Vitro Bacteriostasis effect is suitable.The diseases prevention of relevant Chinese medicine, the effect of curing the disease not only depend on its In Vitro Bacteriostasis effect, also are subjected to the impact of organism metabolism, intestinal microbial population effect.Therefore, whether the fill a prescription effect of control pig winter dysentery of the present invention is better than long-acting terramycin, LIJUNJING etc., and further research awaits.
The present invention's prescription is theoretical according to traditional Chinese veterinarian, in conjunction with modern Chinese medicine pharmaceutical research achievement, sum up forefathers' treatment experience, screening has antibiotic, antivirus action Chinese herbal medicine (Radix Pulsatillae, Cortex Fraxini, Cortex Phellodendri, Fructus Forsythiae etc.), the compound preparation that forms of prescription repeatedly meticulously.Radix Pulsatillae heat-clearing and toxic substances removing in the side, specially controlling hematodiarrhoea except the large intestine heat in blood is principal agent; Cortex Phellodendri, Fructus Forsythiae etc. share and help principal agent heat-clearing and toxic substances removing, cooling blood for hemostasis is accessory drugs; The Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Atractylodis the spleen strengthening and damp drying, Pericarpium Granati astringing to arrest diarrhea are adjuvant drug; The Radix Sanguisorbae coordinating the actions of various ingredients in a prescription is for making.All medicines share to have heat-clearing and toxic substances removing, anti-inflammation, enhancing human body immunity power, adjusts the effect such as gastrointestinal function, so reach diseases prevention, the purpose of cure the disease (disease-resistant health care).
The above only is best mode for carrying out the invention, anyly is familiar with those skilled in the art in the technical scope that the present invention discloses, and the simple change of the technical scheme that can obtain apparently or equivalence are replaced and all fallen within the scope of protection of the present invention.
Claims (2)
1. a pure Chinese medicine formula for the treatment of various animal diarrhoeal diseasess is characterized in that, comprises following composition: Radix Paeoniae Alba 1g, Rhizoma Atractylodis Macrocephalae 1g, Radix Pulsatillae 1g, Rhizoma Atractylodis 1g, Pericarpium Citri Reticulatae 2g, Folium Isatidis 1g, Cortex Phellodendri 1g, Fructus Forsythiae 0.75g, Herba Taraxaci 3g, Cortex Fraxini 1.5g, Radix Sanguisorbae 5g, Pericarpium Granati 1g, Poria 1g.
2. the preparation method of the pure Chinese medicine of the various animal diarrhoeal diseasess of the described treatment of claim 1 is characterized in that prescription according to claim 1 takes by weighing each constituent, put in the baking oven 65 ℃ of lower oven dry, pulverize and be smalls, cross 40 mesh sieves, mix homogeneously is deposited in aeration-drying place after the packing.
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102961717A (en) * | 2012-11-22 | 2013-03-13 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treating domestic animal dyspepsia and preparation method thereof |
| CN103520683A (en) * | 2013-10-21 | 2014-01-22 | 曹远东 | Spleen-tonifying anti-diarrheic granule for piglets and preparation method of granule |
| CN103656093A (en) * | 2013-12-25 | 2014-03-26 | 山东新希望六和集团有限公司 | Drug for treating pig bloody flux and preparation method thereof |
| CN104784322A (en) * | 2015-03-26 | 2015-07-22 | 北京康华远景科技股份有限公司 | Botanical drug composite for treating swine dysentery and preparation method of composite |
| CN104799014A (en) * | 2015-05-20 | 2015-07-29 | 湖北省金谷药业有限公司 | Natural plant feed additive for promoting healthy development of digestive tract of weaned piglet and preparing method thereof |
| CN104996842A (en) * | 2015-08-20 | 2015-10-28 | 兴安县森澳养殖有限公司 | Piglet feed additive |
| CN104997886A (en) * | 2015-07-28 | 2015-10-28 | 句容市浩源生态农业科技有限公司 | Modified attapulgite preparation for prevention and treatment of pullorum disease and preparation method thereof |
| CN105213449A (en) * | 2014-06-30 | 2016-01-06 | 普莱柯生物工程股份有限公司 | A kind of Chinese medicine composition, its preparation method, Chinese medicine preparation and purposes |
| CN108653443A (en) * | 2018-07-16 | 2018-10-16 | 资兴市泰坤农林生态产业有限公司 | A kind of Chinese medicine and the preparation method and application thereof for treating chicken intestinal diorder |
| CN112791156A (en) * | 2021-03-10 | 2021-05-14 | 李崇斌 | Pharmaceutical composition for preventing and treating transmissible gastroenteritis of piglets, preparation method and application |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961717A (en) * | 2012-11-22 | 2013-03-13 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treating domestic animal dyspepsia and preparation method thereof |
| CN102961717B (en) * | 2012-11-22 | 2015-03-04 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treating domestic animal dyspepsia and preparation method thereof |
| CN103520683B (en) * | 2013-10-21 | 2015-06-24 | 曹远东 | Spleen-tonifying anti-diarrheic granule for piglets and preparation method of granule |
| CN103520683A (en) * | 2013-10-21 | 2014-01-22 | 曹远东 | Spleen-tonifying anti-diarrheic granule for piglets and preparation method of granule |
| CN103656093B (en) * | 2013-12-25 | 2015-11-04 | 山东新希望六和集团有限公司 | Be used for the treatment of medicine of Sanguis sus domestica dysentery and preparation method thereof |
| CN103656093A (en) * | 2013-12-25 | 2014-03-26 | 山东新希望六和集团有限公司 | Drug for treating pig bloody flux and preparation method thereof |
| CN105213449A (en) * | 2014-06-30 | 2016-01-06 | 普莱柯生物工程股份有限公司 | A kind of Chinese medicine composition, its preparation method, Chinese medicine preparation and purposes |
| CN104784322A (en) * | 2015-03-26 | 2015-07-22 | 北京康华远景科技股份有限公司 | Botanical drug composite for treating swine dysentery and preparation method of composite |
| CN104784322B (en) * | 2015-03-26 | 2018-08-07 | 北京康华远景科技股份有限公司 | A kind of plant drug composition and preparation method thereof for treating pig dysentery characterized by blood in the stool |
| CN104799014A (en) * | 2015-05-20 | 2015-07-29 | 湖北省金谷药业有限公司 | Natural plant feed additive for promoting healthy development of digestive tract of weaned piglet and preparing method thereof |
| CN104997886A (en) * | 2015-07-28 | 2015-10-28 | 句容市浩源生态农业科技有限公司 | Modified attapulgite preparation for prevention and treatment of pullorum disease and preparation method thereof |
| CN104997886B (en) * | 2015-07-28 | 2018-09-25 | 句容市浩源生态农业科技有限公司 | A kind of modified attapulgite preparation and preparation method thereof of prevention white diarrhea |
| CN104996842A (en) * | 2015-08-20 | 2015-10-28 | 兴安县森澳养殖有限公司 | Piglet feed additive |
| CN108653443A (en) * | 2018-07-16 | 2018-10-16 | 资兴市泰坤农林生态产业有限公司 | A kind of Chinese medicine and the preparation method and application thereof for treating chicken intestinal diorder |
| CN112791156A (en) * | 2021-03-10 | 2021-05-14 | 李崇斌 | Pharmaceutical composition for preventing and treating transmissible gastroenteritis of piglets, preparation method and application |
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Application publication date: 20130403 |