CN103550513B - A kind of Chinese medicine treating cholestatic hepatitis - Google Patents
A kind of Chinese medicine treating cholestatic hepatitis Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine treating cholestatic hepatitis, the medical material of following weight proportion be prepared from: Fructus Litseae 14 parts, Herba Moslae 12 parts, Herba Triostei himalayani 8 parts, herba meliloti 10 parts, twoflower rattlesnake plantain 14 parts, the Strobilus Pini 14 parts, Cortex capparis Bodinieri radicis 16 parts, Ramulus et Folium Semiliquidambaris cathayensis 8 parts, Auricled Hedyotis Herb 14 parts, Herba speranskiae cantonensis 13 parts, tamarind 16 parts, Coriaria sinica 15 parts, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 12 parts, Folium Combreti Alferedii 14 parts, Herba Hemiboeae 8 parts, Radix Codonopsis Convolvulaceae 10 parts, Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) 12 parts。Clinical trial certificate, the present invention can safely and effectively treat cholestatic hepatitis。
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine treating cholestatic hepatitis。
Background technology
Cholestatic hepatitis is to cause hepatocyte and (or) bile capillary paracholia because of many reasons, causes partially or completely property bile flow retardance。Multiple acute hepatitis of being born in is fallen ill after several weeks。Cholestatic hepatitis is to cause hepatocyte and (or) bile capillary paracholia because of many reasons, causes that partially or completely the retardance of property bile flow is the syndrome of feature, accounts for the 2～8% of icterohepatitis。
Cholestatic hepatitis is still lacked at present to the effective medicine of generally recognized as safe。
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Fructus Litseae [source] this product is Lauraceae Litsea plant cubeb litsen tree Litseacubeba (Lour.) Pers., with fruit, root and leaf。Gathering during fruit maturation in autumn, root, leaf can be adopted the whole year, remove impurity, dry。[function cures mainly] warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain。Root: for cold syndrome of the stomach vomiting, coldness and pain in the epigastrium, colic of cold type is suffered from abdominal pain, stagnancy of cold-damp, turbid urine。
The wounded in the battle herb that Herba Moslae [source] is labiate elsholtzia splendens。[function cures mainly] diaphoresis expelling summer-heat, row water wet dissipation, during stomach warming is adjusted。Controlling Xia Yue sense cold fluid-retention cold, have a headache and fever, aversion to cold is lossless, and the feeling of stuffiness in chest is suffered from abdominal pain, vomiting and diarrhoea, edema, beriberi。
Herba Triostei himalayani [source] the Caprifoliaceae stem of a herb platymiscium punching stem of a herb sugarcane TriosteumhimalayanumWall.[T.fargesiiFranch.], it is used as medicine with whole herb with root。Xia Qiu excavates, and cleans and dries。[function cures mainly] inducing diuresis to remove edema, promoting blood flow to regulate menstruation。For edema, dysuria, menoxenia。
Herba meliloti [source] pulse family melilot Herba Meliloti officinalis Melilotusofficinalis (L.) Desr., with all herbal medicine。Summer adopts, and cleans and dries。[function cures mainly] relieving spasm to stop pain。For asthma, bronchitis, intestinal colic；Wound is controlled in external, and lymph node swells and ache。
Twoflower rattlesnake plantain [source] the orchid family jade phoenix flower plant Pluma Anseris domestica jade phoenix flower Habenariadentata (Swartz) Schlecht. (HabenariamiersianaChamp.), is used as medicine with tuber。Autumn and winter excavate, and clean steaming, dry or using fresh herb。[function cures mainly] tonifying the lung kidney, diuresis。For lumbago due to renal deficiency, body is empty after being ill, impotence due to deficiency of the kidney, colicky, stomachache, and pulmonary tuberculosis is coughed, orchitis, urinary tract infection。
The cone of the Strobilus Pini [source] Pinaceae pine genus plant lacebark pine (Periostracum Serpentis pine, Budgerigar pine) PinusbungeanaZucc.。[function cures mainly] eliminates the phlegm, and cough-relieving is relievingd asthma。Chronic tracheitis, asthma, cough with copious phlegm。
Cortex capparis Bodinieri radicis [source] Capparidaceae Chinese lime platymiscium Cortex capparis Bodinieri radicis, is used as medicine with Herb, root bark。Autumn and winter gather, and clean section, dry。[function cures mainly] relaxing muscles and tendons and activating QI and blood in the collateral, heat-clearing and toxic substances removing。Herb: for rheumatalgia, traumatic injury；Root bark: tonsillitis, toothache。
Ramulus et Folium Semiliquidambaris cathayensis [source] is Hamamelidaceae Altingia plant Ramulus et Folium Semiliquidambaris cathayensis AltingiachingiiMetc, is used as medicine with root or branch, leaf。The whole year can adopt, and dries standby respectively。[function cures mainly] expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation。For rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise；External is controlled on cutter hemorrhage。
The herb of Auricled Hedyotis Herb [source] Rubiaceae plants of Hedyotis Auricled Hedyotis Herb HedyotisauriculariaL.。The whole year can adopt, and cleans, using fresh herb or dry。[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling。For cold, fever, cough due to lung-heat, laryngalgia, acute conjunctivitis, enteritis, dysentery；Venom, traumatic injury, ulcerative carbuncle toxic swelling, mastitis, eczema are controlled in external。
Herba speranskiae cantonensis [source] Euphorbiaceae Speranskia plant tumor fruit speranskia tuberculata Speranskiacantoniensis (Hance) PxetHoffm., with all herbal medicine。Autumn gathers herb, dries。[function cures mainly] dispels wind and removes dampness, promoting blood flow to regulate menstruation, pain relieving。For catching a cold, cough due to consumptive disease, tuberculous lymphadenitis, rheumatic arthritis, sciatica, traumatic injury, menoxenia, leucorrhea。
Tamarind [source] pulse family tamarind platymiscium tamarind TamarindusindicaL., with fruit medicine。Spring adopts, and removes seed, dries。[function cures mainly] clearing away summer-heat, promoting digestion and removing stagnation。For heatstroke, inappetence, infantile malnutrition, vomiting during pregnancy, constipation。
Coriaria sinica [source] Coriariaceae Coriaria plant Coriaria sinica CoriariasinicaMaxim., is used as medicine with root, leaf。Root is excavated winter, scrapes off crust, dries；Leaf is adopted summer, dries。[function cures mainly] expelling wind and removing dampness, analgesia, parasite killing。Root: for tuberculous lymphadenitis, traumatic injury, lyssodexis, rheumatic arthritis；Leaf: burn and scald, tinea capitis, eczema, sore swollen toxin are controlled in external。
Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) [source] is wrapped up in hedge firewood platymiscium for Acanthaceae and is wrapped up in hedge firewood GendarussavulgarisNees[JusticiagendarussaL.F.] it is used as medicine with Herb。The whole year can adopt, and cleans and dries or using fresh herb。[function cures mainly] reunion of fractured tendons and bones, reducing swelling and alleviating pain。For fracturing, bruise, rheumatic arthritis。
Folium Combreti Alferedii [source] the Combretum Racemosum Combretum CombretumalfrediiHance of plant windmill, is used as medicine with root, leaf。Autumn and winter adopt, and clean using fresh herb or dry in the shade。[function cures mainly] root: heat clearing away, function of gallbladder promoting。For icterohepatitis。Leaf: anthelmintic。For ascariasis, trichuriasis。The fresh leaf of external controls burn and scald。
Herba Hemiboeae [source] Gesneriaceae Hemiboea plant Herba Hemiboeae HemiboeasubcapitaraClarke, with all herbal medicine。Adopt after autumn, clean and dry。[function cures mainly] detoxifies。For venom, furuncle。
Radix Codonopsis Convolvulaceae [source] campanulaceae Codonopsis plant Radix Codonopsis Convolvulaceae CodonopsisconvolvulaceaKurz., is used as medicine with root。Autumn excavates, and cleans and dries。[function cures mainly] invigorating QI and blood, the lung moistening and production of body fluid promoting。For anemia, spontaneous perspiration, deficiency of lung-YIN is coughed, neurasthenia。
The alabastrum of Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) [source] thymelaeceae Flos Wikstroemiae Dolichanthae platymiscium Wikstroemia chamaedaphne (Bge.) Meisn. WikstroemiachamaedaphneMeisn., leaf also can be used as medicine。Pick flowers early autumn flower bud and leaf, dry in the shade or dry。[function cures mainly] removing water retention by purgation, relieving constipation。For edema distension, phlegm retention is gathered, cough with dyspnea dyspnea with fullness of the chest, acute and chronic infectious hepatitis, schizophrenia, epilepsy。
Summary of the invention
It is desirable to provide a kind of Chinese medicine treating cholestatic hepatitis, by selecting suitable medical material and proportioning thereof, reach safely and effectively to cure the purpose of cholestatic hepatitis。
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine treating cholestatic hepatitis, it is characterized in that, the medical material of following weight proportion be prepared from: Fructus Litseae 14 parts, Herba Moslae 12 parts, Herba Triostei himalayani 8 parts, herba meliloti 10 parts, twoflower rattlesnake plantain 14 parts, the Strobilus Pini 14 parts, Cortex capparis Bodinieri radicis 16 parts, Ramulus et Folium Semiliquidambaris cathayensis 8 parts, Auricled Hedyotis Herb 14 parts, Herba speranskiae cantonensis 13 parts, tamarind 16 parts, Coriaria sinica 15 parts, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 12 parts, Folium Combreti Alferedii 14 parts, Herba Hemiboeae 8 parts, Radix Codonopsis Convolvulaceae 10 parts, Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) 12 parts。
Below in conjunction with clinical laboratory data, beneficial effects of the present invention is described:
1, physical data
The out-patient of 80 example cholestatic hepatitiss is collected altogether between inventor's in JIUYUE, 2009 in December ,-2012, age 24-60 year, course of disease 1-7。It is randomly divided into: treatment group 55 example, blank group 25 examples。Two groups of data such as age, the state of an illness there was no significant difference, and has comparability。
2, test method
The capsule that the oral present invention specific embodiment 1 of 2.1 treatment groups prepares, sooner or later respectively once。7 days courses for the treatment of。
2.2 blank group oral placebo capsules, sooner or later respectively once。7 days courses for the treatment of。
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal。Taking a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or normal。Invalid: clinical symptoms is without being clearly better or increasing the weight of。
3.2 treatment statistical results are in Table 1。
1 liang of table group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Untoward reaction example | Total effective rate (%) |
| Treatment group | 55 | 11 (20%) | 32 (58.2%) | 12 (21.8%) | 0 | 78.2% |
| Blank group | 25 | 0 | 7 (28%) | 18 (72%) | 0 | 28% |
Visible, cholestatic hepatitis can safely and effectively be controlled by the medicine that the present invention prepares。
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment。
Specific embodiment 1
Weigh: Fructus Litseae 14 grams, Herba Moslae 12 grams, Herba Triostei himalayani 8 grams, herba meliloti 10 grams, twoflower rattlesnake plantain 14 grams, the Strobilus Pini 14 grams, Cortex capparis Bodinieri radicis 16 grams, Ramulus et Folium Semiliquidambaris cathayensis 8 grams, Auricled Hedyotis Herb 14 grams, Herba speranskiae cantonensis 13 grams, tamarind 16 grams, Coriaria sinica 15 grams, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 12 grams, Folium Combreti Alferedii 14 grams, Herba Hemiboeae 8 grams, Radix Codonopsis Convolvulaceae 10 grams, Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) 12 grams, add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour, filters；Merging filtrate, concentration, dry, load capsule shells, the capsule of 1 day consumption of adult normal must be met。
For treating cholestatic hepatitis。Oral, every bu is taken for twice sooner or later。
Specific embodiment 2
Weigh: Fructus Litseae 14 grams, Herba Moslae 12 grams, Herba Triostei himalayani 8 grams, herba meliloti 10 grams, twoflower rattlesnake plantain 14 grams, the Strobilus Pini 14 grams, Cortex capparis Bodinieri radicis 16 grams, Ramulus et Folium Semiliquidambaris cathayensis 8 grams, Auricled Hedyotis Herb 14 grams, Herba speranskiae cantonensis 13 grams, tamarind 16 grams, Coriaria sinica 15 grams, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 12 grams, Folium Combreti Alferedii 14 grams, Herba Hemiboeae 8 grams, Radix Codonopsis Convolvulaceae 10 grams, Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) 12 grams, add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour, filters；Merging filtrate, concentration, dry, pulverize, the powder of 1 day consumption of adult normal must be met。
For treating cholestatic hepatitis。Oral, every bu is taken for twice sooner or later。
Specific embodiment 3
Weigh: Fructus Litseae 14 grams, Herba Moslae 12 grams, Herba Triostei himalayani 8 grams, herba meliloti 10 grams, twoflower rattlesnake plantain 14 grams, the Strobilus Pini 14 grams, Cortex capparis Bodinieri radicis 16 grams, Ramulus et Folium Semiliquidambaris cathayensis 8 grams, Auricled Hedyotis Herb 14 grams, Herba speranskiae cantonensis 13 grams, tamarind 16 grams, Coriaria sinica 15 grams, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 12 grams, Folium Combreti Alferedii 14 grams, Herba Hemiboeae 8 grams, Radix Codonopsis Convolvulaceae 10 grams, Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) 12 grams, add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour, filters；Merging filtrate, concentration, dry, add appropriate dextrin and correctives, granulate according to this area common process, packaging, can be prepared by meeting the granule of 1 day consumption of adult normal。
For treating cholestatic hepatitis。Oral, every bu is taken for twice sooner or later。
Claims (1)
1. the Chinese medicine treating cholestatic hepatitis, it is characterized in that, the medical material of following weight proportion be prepared from: Fructus Litseae 14 parts, Herba Moslae 12 parts, Herba Triostei himalayani 8 parts, herba meliloti 10 parts, twoflower rattlesnake plantain 14 parts, the Strobilus Pini 14 parts, Cortex capparis Bodinieri radicis 16 parts, Ramulus et Folium Semiliquidambaris cathayensis 8 parts, Auricled Hedyotis Herb 14 parts, Herba speranskiae cantonensis 13 parts, tamarind 16 parts, Coriaria sinica 15 parts, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 12 parts, Folium Combreti Alferedii 14 parts, Herba Hemiboeae 8 parts, Radix Codonopsis Convolvulaceae 10 parts, Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) 12 parts。
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| CN104940838A (en) * | 2015-07-16 | 2015-09-30 | 王艳娣 | Traditional Chinese medicine composition for treating cholestatic hepatitis |
| CN105597026A (en) * | 2016-03-03 | 2016-05-25 | 青岛市黄岛区中医医院 | Traditional Chinese medicine decoction for treating cholestatic hepatitis |
| CN105853806A (en) * | 2016-05-27 | 2016-08-17 | 王德欣 | Traditional Chinese medicine for treating cholestatic hepatitis and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1539490A (en) * | 2003-11-04 | 2004-10-27 | 向忠友 | Chinese traditional medicine for curing cholestatic hepatitis and preparing method |
| CN1899572A (en) * | 2006-07-21 | 2007-01-24 | 贺长青 | Chinese medicine for treating hepatitis B and its preparing method |
| CN101152467A (en) * | 2007-09-28 | 2008-04-02 | 天津飞鹰制药有限公司 | Traditional Chinese medicine preparation for treating urgent and chronic hepatitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1539490A (en) * | 2003-11-04 | 2004-10-27 | 向忠友 | Chinese traditional medicine for curing cholestatic hepatitis and preparing method |
| CN1899572A (en) * | 2006-07-21 | 2007-01-24 | 贺长青 | Chinese medicine for treating hepatitis B and its preparing method |
| CN101152467A (en) * | 2007-09-28 | 2008-04-02 | 天津飞鹰制药有限公司 | Traditional Chinese medicine preparation for treating urgent and chronic hepatitis |
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