CN103690715B - A kind of Chinese medicine for the treatment of ischemic colitis - Google Patents
A kind of Chinese medicine for the treatment of ischemic colitis Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine for the treatment of ischemic colitis, be prepared from by the medical material of following weight proportion: break Jin 10 parts, adder's-fern 14 parts, Euonymus japonicus 14 parts, Herba Arenariae Serpyllifoliae 16 parts, hemlock chervil 10 parts, DAJIANJU 12 parts, Radix Atalantiae Buxifoliae 12 parts, Herba Scindapsi Officinalis 12 parts, Fructus Lithospermi Zollingeri 14 parts, vinegar woods 14 parts, herba meliloti 12 parts, the Strobilus Pini 10 parts, Herba thalictri sibirici 8 parts, Radix scopoliae sinensis 12 parts, Radix seu Folium Wendlandiae Uvariifoliae 8 parts, Caulis et Folium Viburni Ichangensis 14 parts, 15 parts, Bai Le catechu, Herba Thermopsis Lanceolatae 12 parts, Flammulina velutipes 8 parts by a fall.Clinical trial certificate, the present invention can safe and effective treatment ischemic colitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of ischemic colitis.
Background technology
Ischemic colitis (ischemiccolitis, IC) is the ischemic lesions that the intestinal wall Oligemia caused due to a variety of causes causes certain section of colon wall blood supply deficiency or backflow obstruction, makes the dystrophic a kind of syndrome of intestinal wall.Its early lesion is confined to mucous layer and tela submucosa, and clinical manifestation has stomachache, has blood in stool and suffer from diarrhoea, and severe patient can cause bowel necrosis, perforation, peritonitis and septic shock, is one of common cause of lower digestive tract hemorrhage, makes a definite diagnosis comparatively difficulty in early days.
The effective medicine of generally recognized as safe is still lacked at present for ischemic colitis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Break leaf, thorn and seed that Jin [source] is Flacourtiaceae plant longleaf xylosma by a fall.[function cures mainly] seed: control amenorrhea, skin ulcer tinea, scrofula; Thorn: lactogenic.Cool the blood dissipate blood stasis, reducing swelling and alleviating pain.
The rhizome that adder's-fern [source] is Plants of Polypodiaceae adder's-fern and Rhizoma Polygoni vivipari.The whole year all can excavate, and removing impurity, cleans, using fresh herb or dry.[function cures mainly] clearing away heat-damp and promoting diuresis detoxifies.Main damp and hot stranguria; Beriberoid pyretic arthralgia; Furuncle carbuncle; Rubella pruritus; Traumatic injury.
The peel of stem that Euonymus japonicus [source] is Celastraceae plant Euonymus japonicus EuonymusjaponzcusThunb. and branch.The whole year all can adopt, and cutting or bark dry.[function cures mainly] dispels the wind temperature; Bone and muscle strengthening; Promoting blood circulation and hemostasis.Main air pain of dampness syndrome; Soreness of the waist and knees; Traumatic injury wound is swollen; Fracture; Spit blood.
The herb that Herba Arenariae Serpyllifoliae [source] is pinkwort sandwort.[function cures mainly] heat clearing away, improving eyesight, removing toxic substances.Control conjunctival congestion, cough, gingivitis.
Hemlock chervil [source] Umbelliferae Torilis plant hemlock chervil Torilisjaponica(Houtt.) DC.[function cures mainly] promoting blood circulation and detumescence, convergence parasite killing.For chronic diarrhea, ascariasis; External is controlled carbuncle sore and is not closed up for a long time, trichomonas vaginitis.
The flower that DAJIANJU [source] is feverfew west szechwan pyrethrum.The 8-9 month gathers, and removing impurity, dries.[function cures mainly] dissipating blood stasis; Pain relieving.Main traumatic injury; Born of the same parents' backache; Headache.
Radix Atalantiae Buxifoliae [source] is the root of rutaceae wine cake Jin.The pain relieving of [function cures mainly] blood stasis removing, pleasantly reduces phlegm.Control treating swelling and pain by traumatic injury, fracture, rheumatalgia, hernia, flu, cough, malaria, stomachache.
Herba Scindapsi Officinalis [source] Araeceae Scindapsus plant Herba Scindapsi Officinalis ScindapsusofficinalisSchott, is used as medicine with Herb.The four seasons can adopt, and clean, dry.[function cures mainly] clearing away lung-heat to relieve cough, reunion of fractured tendons and bones.For upper respiratory tract infection, bronchitis, pertussis, angina pectoris, traumatic injury, fracture, bones and muscles pain.
The fruit that Fructus Lithospermi Zollingeri [source] is comfrey zollinger gromwell or large Radix Arnebiae (Radix Lithospermi).The 7-9 month gathers when fruit is ripe, dries.[function cures mainly] warming spleen and stomach for dispelling cold; Reducing swelling and alleviating pain; Reducing swelling and alleviating pain.Main bright gastral cavity cold type of pain is done swollen; General acid regurgitation water; Treating swelling and pain by traumatic injury; Fracture.
The fruit that vinegar woods [source] are rosaceous plant Photinia.Gather during 9-10 month fruit maturation, dry.[function cures mainly] parasite killing; Hemostasis; Astringing intestine to stop diarrhea; Promote the production of body fluid; Relieve the effect of alcohol.Main ascarid stomachache; Anal fistula hematochezia; Chronic dysentery.
Herba meliloti [source] pulse family melilot Herba Meliloti officinalis Melilotusofficinalis(L.) Desr., with all herbal medicine.Summer adopts, and cleans and dries.[function cures mainly] relieving spasm to stop pain.For asthma, bronchitis, intestinal colic; Wound is controlled in external, and lymph node swells and ache.
The cone of the Strobilus Pini [source] Pinaceae pine genus plant lacebark pine (Periostracum Serpentis is loose, Budgerigar is loose) PinusbungeanaZucc..[function cures mainly] eliminates the phlegm, and cough-relieving is relievingd asthma.Chronic tracheitis, asthma, cough with copious phlegm.
The herb that Herba thalictri sibirici [source] is hair breeding plant Herba thalictri sibirici or root and rhizome.Autumn excavates root and rhizome, removes silt particle, dries; Summer adopts herb, dries.[function cures mainly] heat-clearing and toxic substances removing.Control cough due to lung-heat, angina.
The root that Radix scopoliae sinensis [source] is the new hyoscyami of plant of Solanaceae.[function cures mainly] delivers cold expelling, relaxing muscles and tendons and activating QI and blood in the collateral, pain relieving.
Radix seu Folium Wendlandiae Uvariifoliae [source] Rubiaceae Radix seu Folium Wendlandiae Uvariifoliae platymiscium Radix seu Folium Wendlandiae Uvariifoliae WendlandiauvariifoliaHance, with root, leaf is used as medicine.The whole year can adopt, and cleans, using fresh herb or dry.[function cures mainly] expelling wind and removing dampness, dissipating blood stasis for subsidence of swelling, hemostasia and promoting granulation.Root: for rheumatic arthritis, traumatic injury.Leaf: traumatic hemorrhage is controlled in external, skin infection festers and does not close up for a long time.
Stem, leaf, root that Caulis et Folium Viburni Ichangensis [source] is caprifoliaceae plant Yichang Caulis Viburni Dilatati.Stem, leaf, gather when growing vigorous; Root, the whole year can adopt.Dry.[function cures mainly] expelling wind and cold, removing dampness to relieve itching.
Bai Le catechu [source] is that pulse family Bai Le Pterostyrax plant Bai Le sets Dichirostachysglomerata(Forsk) the decocting extractum of branch of Chiov..[function cures mainly] hemostasis antidiarrheal, sore analgesic therapy.Hemorrhage for taste-blindness rate.
The herb that Herba Thermopsis Lanceolatae [source] is leguminous plant experiment of general alkaloid of Thermopsis.[function cures mainly] eliminates the phlegm, cough-relieving.Control cough phlegm dyspnea.
The sporophore that Flammulina velutipes [source] is Bai Mo section fungus Flammulina velutipes.[function cures mainly] tonifying liver; Benefit the intestines and stomach; Anticancer.Main hepatopathy; Gastrointestinal tract inflammation; Ulcer; Cancer.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of ischemic colitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing ischemic colitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of ischemic colitis, it is characterized in that, be prepared from by the medical material of following weight proportion: break Jin 10 parts, adder's-fern 14 parts, Euonymus japonicus 14 parts, Herba Arenariae Serpyllifoliae 16 parts, hemlock chervil 10 parts, DAJIANJU 12 parts, Radix Atalantiae Buxifoliae 12 parts, Herba Scindapsi Officinalis 12 parts, Fructus Lithospermi Zollingeri 14 parts, vinegar woods 14 parts, herba meliloti 12 parts, the Strobilus Pini 10 parts, Herba thalictri sibirici 8 parts, Radix scopoliae sinensis 12 parts, Radix seu Folium Wendlandiae Uvariifoliae 8 parts, Caulis et Folium Viburni Ichangensis 14 parts, 15 parts, Bai Le catechu, Herba Thermopsis Lanceolatae 12 parts, Flammulina velutipes 8 parts by a fall.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
The out-patient of 116 routine ischemic colitiss is collected altogether, age 26-55 year, course of disease 1-5 between inventor's in December, 2011 in JIUYUE ,-2012.Be divided at random: treatment group 84 example, blank group 32 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, test chamber inspection is normal, observes having no recurrence in three months more afterwards.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) | Untoward reaction example |
| Treatment group | 84 | 23（27.4%） | 43（51.2%) | 18（21.4%) | 78.6% | 0 |
| Blank group | 32 | 0 | 6（18.7%） | 26（81.3%） | 18.7% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment ischemic colitis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
specific embodiment 1
Take: break Jin 10 grams, adder's-fern 14 grams, Euonymus japonicus 14 grams, Herba Arenariae Serpyllifoliae 16 grams, hemlock chervil 10 grams, DAJIANJU 12 grams, Radix Atalantiae Buxifoliae 12 grams, Herba Scindapsi Officinalis 12 grams, Fructus Lithospermi Zollingeri 14 grams, vinegar woods 14 grams, herba meliloti 12 grams, the Strobilus Pini 10 grams, Herba thalictri sibirici 8 grams, Radix scopoliae sinensis 12 grams, Radix seu Folium Wendlandiae Uvariifoliae 8 grams, Caulis et Folium Viburni Ichangensis 14 grams, 15 grams, Bai Le catechu, Herba Thermopsis Lanceolatae 12 grams, Flammulina velutipes 8 grams by a fall, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of ischemic colitis.Oral, every bu is taken for twice sooner or later.
specific embodiment 2
Take: break Jin 10 grams, adder's-fern 14 grams, Euonymus japonicus 14 grams, Herba Arenariae Serpyllifoliae 16 grams, hemlock chervil 10 grams, DAJIANJU 12 grams, Radix Atalantiae Buxifoliae 12 grams, Herba Scindapsi Officinalis 12 grams, Fructus Lithospermi Zollingeri 14 grams, vinegar woods 14 grams, herba meliloti 12 grams, the Strobilus Pini 10 grams, Herba thalictri sibirici 8 grams, Radix scopoliae sinensis 12 grams, Radix seu Folium Wendlandiae Uvariifoliae 8 grams, Caulis et Folium Viburni Ichangensis 14 grams, 15 grams, Bai Le catechu, Herba Thermopsis Lanceolatae 12 grams, Flammulina velutipes 8 grams by a fall, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of ischemic colitis.Oral, every bu is taken for twice sooner or later.
specific embodiment 3
Take: break Jin 10 grams, adder's-fern 14 grams, Euonymus japonicus 14 grams, Herba Arenariae Serpyllifoliae 16 grams, hemlock chervil 10 grams, DAJIANJU 12 grams, Radix Atalantiae Buxifoliae 12 grams, Herba Scindapsi Officinalis 12 grams, Fructus Lithospermi Zollingeri 14 grams, vinegar woods 14 grams, herba meliloti 12 grams, the Strobilus Pini 10 grams, Herba thalictri sibirici 8 grams, Radix scopoliae sinensis 12 grams, Radix seu Folium Wendlandiae Uvariifoliae 8 grams, Caulis et Folium Viburni Ichangensis 14 grams, 15 grams, Bai Le catechu, Herba Thermopsis Lanceolatae 12 grams, Flammulina velutipes 8 grams by a fall, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of ischemic colitis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of ischemic colitis for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: break Jin 10 parts, adder's-fern 14 parts, Euonymus japonicus 14 parts, Herba Arenariae Serpyllifoliae 16 parts, hemlock chervil 10 parts, DAJIANJU 12 parts, Radix Atalantiae Buxifoliae 12 parts, Herba Scindapsi Officinalis 12 parts, Fructus Lithospermi Zollingeri 14 parts, vinegar woods 14 parts, herba meliloti 12 parts, the Strobilus Pini 10 parts, Herba thalictri sibirici 8 parts, Radix scopoliae sinensis 12 parts, Radix seu Folium Wendlandiae Uvariifoliae 8 parts, Caulis et Folium Viburni Ichangensis 14 parts, 15 parts, Bai Le catechu, Herba Thermopsis Lanceolatae 12 parts, Flammulina velutipes 8 parts by a fall.
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| 溃疡性结肠炎的中医药治疗进展;苏婷，石显方;《光明中医》;20130930;第28卷(第9期);1977－1980 * |
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