CN103599328A - Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis - Google Patents
Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treatment of pulmonary alveolar proteinosis. The traditional Chinese medicine is made from the following medicinal materials by weight: 15 parts of spirea, 12 parts of Porana racemosa, 12 parts of Sedum lineare, 10 parts of Anemone dichotoma roots, 10 parts of gambier, 12 parts of Cayratia japonica, 14 parts of Pyrethrum tatsienense, 18 parts of suberect spatholobus stems, 8 parts of Rhizoma Dioscoreae Hypoglaucae, 22 parts of Clerodendrum yunnanense flowers, 20 parts of stems and leaves of Viburnum taitoense Hayata, 16 parts of Dicranum majus, 15 parts of Cissus assamica (Laws.) Craib, 10 parts of straightstalk alpine meadowrue roots, 14 parts of Panax pseudo-ginseng var. bipinnatifidus, 16 parts of Calystegia hederacea, and 12 parts of Coprinus sterqulinus Fr. Clinical experiments prove that the traditional Chinese medicine provided by the invention is safe and effective for treatment of pulmonary alveolar proteinosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of pulmonary alveolar proteinosis.
Background technology
Pulmonary alveolar proteinosis (PAP) is the not bright Uncommon Diseases of a kind of reason.Be characterized in having in alveolar the rich phospholipoprotein deposition of insolubility, clinical symptoms main manifestations for breathing hard, cough and expectoration.Chest x-ray Cheng Shuanfei diffusivity pulmonary infiltrates shade.It is feature that pathological examination be take the protein-like substance that is filled with periodic acid snow husband (PAS) stained positive in alveolar.The clinical manifestation of primary disease is widely different, and what have can, without any clinical symptoms, only find when health check-up; Approximately having 1/5 patient to take Secondary cases pulmonary infection symptom is First presentation, has cough, heating, chest discomfort etc.; Separately have an appointment 1/2 the hidden onset of attacking of patient, shows as cough, dyspnea, weak, and minority case can have low grade fever and spitting of blood, and respiratory symptom and the pulmonary lesion scope of getting involved have certain relation.
For pulmonary alveolar proteinosis, still lack at present the effective medicine of generally recognized as safe.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Ramulus et Folium Spiraeae Salicifolia [source] Rosaceae Spiraea light leaf Ramulus et Folium Spiraeae Salicifolia, is used as medicine with root and tender leaf.Adopt root the whole year, clean and dry; Tender leaf is adopted summer.[function cures mainly] heat-clearing and toxic substances removing.For conjunctival congestion and swelling pain, headache, toothache, cough due to lung-heat; Wound hemorrhage is controlled in external.
Moth rattan [source] Convolvulaceae moth rattan Porana racemosa Roxb., with all herbal medicine.[function cures mainly] delivers, helps digestion long-pending.Cure mainly Common Cold, food stagnation does not disappear.
Herba Sedi Linearis [source] is the stem and leaf of crassulaceae plants Herba Sedi Linearis.Using fresh herb is with adopting; Or summer, Qiu Liangji, extract Herb, clean, decontrol in water and scald, pick up, dry or a heatable brick bed dry.[function cures mainly] heat-clearing and toxic substances removing; Dampness removing; Hemostasis.Main laryngopharynx swelling and pain; Conjunctival congestion toxic swelling; Pyretic toxicity carbuncle; Furuncle; Erysipelas; Herpes zoster; Burn and scald; Venom; Jaundice; Damp-heat dysentery; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Verruca plana.
Two discrimination Anemone cathayensis Kitag. roots [source] are the rhizome of ranunculaceae plant two discrimination Anemone cathayensis Kitag..Excavate autumn, dries.[function cures mainly] relaxing muscles and tendons to promote blood circulation; Heat-clearing and toxic substances removing.Main traumatic injury; Rheumatic arthritis; Dysentery; Carbuncle sore.
GAMBIER [source] is decocted juice for Maguireothamnus speciosus Uncaria gambier Roxb. band leaf twig and is concentrated the dry extract forming.For Maguireothamnus speciosus Uncaria gambier Roxb. band leaf twig is decocted the concentrated dry extract forming of juice.
Abacopteris penangiana (Hook.) Ching [source] is rhizome and the herb of Thelypteridaceae plant Pronephrium penangianum.Gather autumn.[function cures mainly] dissipating blood stasis blood, dehumidifying.Control lumbago due to trauma, the blood clotting stagnation of QI.
Flos Pyrethri tatsienensis [source] is the head inflorescence of feverfew Flos Pyrethri tatsienensis.8～JIUYUE is picked flowers, and dries in the shade.[function cures mainly] invigorates blood circulation, damp eliminating, antiinflammatory, pain relieving.Control traumatic injury, damp-heat syndrome.
Kadsura interior [source] is the rattan of Schisandraceae Plant Kadsura interior or Kadsura heteroclita.Gather autumn, cleans and dry use, or endure cream and use.[function cures mainly] hemopoietic and blood; Regulating menstruation seed.Main deficient qi and blood; The paralysis of limb fiber crops; Rheumatic arthralgia; Deficient sterile; Seminal emission nebulousurine; Menoxenia; Leucorrhea with red and white discharge.
Rhizoma Dioscoreae Hypoglaucae [source] this product is the dry rhizome of Dioscoreaceae Plant Powder back of the body Rhizoma Dioscoreae Dioscorea hypoglauca Palibin.Autumn, two seasons of winter excavate, and remove fibrous root, clean, and section, dries.[function cures mainly] dampness removing goes turbid, wind expelling stagnation removing.For stranguria marked by chyluria, nebulousurine, leukorrhagia, rheumatic arthralgia, articular instability, lumbocrural pain.
Radix clerodendri yunnanensis flower [source] is the flower of Verbenaceae Radix clerodendri yunnanensis.The 4-7 month gathers while blooming, and dries.[function cures mainly] hemostasis; Leukorrhagia stopping.Main metrorrhagia; Leukorrhagia.
It to leaf oil Folium Cannabis [source], is the stem and leaf of Radix Ophiopogonis plant platform Dong Caulis Viburni Dilatati.Spring, summer gather, using fresh herb.[function cures mainly] eliminating stasis to stop pain; Relieving constipation.Main traumatic injury; Constipation.
The bent tail moss of many capsules [source] are the plant of the bent tail moss of the many capsules of Dicranaceae plant.Summer, autumn gather, and clean, and dry.[function cures mainly] clearing away lung-heat to relieve cough.Main cough due to lung-heat.
Fan blade rattan [source] Vitaceae fan blade rattan Cissus assamica (Laws.) Craib, is used as medicine with root.[function cures mainly] detumescence of drawing out the pus, eliminating stasis to stop pain.Cure mainly traumatic injury, sprain, Fengshi Guanjie pain, fracture, carbuncle pyogenic infections from tumour or sore.Formula is with still controlling osteomyelitis.Also can make nourishing agent.
Radix Thalictri elati [source] is the root of ranunculaceae plant compound leaf Herba Veratri Taliensis.Autumn, winter gather, and clean and dry.[function cures mainly] heat clearing and damp drying, removing pathogenic heat from blood and toxic substance from the body.Control dysphoria with smothery sensation thirsty, vomiting uncomfortable in chest, hematemesis and epistaxis, damp-heat dysentery, conjunctival congestion aphtha, carbuncle furunculosis, jaundice caused by damp-heat.
Rhizoma Panacis bipinnatifidi [source] is araliaceae ginseng plant's Rhizoma Panacis bipinnatifidi Panax bipinnatifidus Seem., with root stock, is used as medicine.Autumn end excavates, clean dry standby.[function cures mainly] strengthening by means of tonics, eliminating stasis to stop pain, hemostasis.For weak after being ill, hemoptysis of pulmonary tuberculosis, epistaxis, amenorrhea, puerperal abdominal pain due to blood stasis, arthralgia due to cold-dampnes, traumatic injury.
DAWANHUA [source] is Convolvulaceae calystegia plant DAWANHUA Calystegin hederacea Wall., with root stock and flower, is used as medicine.Dig root stock autumn, clean and dry or using fresh herb.The Xia Qiu using fresh herb of picking flowers.[function cures mainly] invigorating the spleen and benefiting QI, diuresis, regulating menstruation, leukorrhagia stopping; For insufficiency of the spleen dyspepsia, menoxenia, leucorrhea, milk is rare.Pain relieving; Toothache is controlled in external.
Excrement ghost umbrella [source] Mycophyta Basidiomycetes Agaricales Agaricaceae excrement ghost umbrella Coprinus sterquilinus Fr., is used as medicine with sporophore.[function cures mainly] beneficial the intestines and stomach, phlegm-eliminiating and qi-regulating, removing toxic substances, detumescence.Often eating can be aid digestion, eliminates the phlegm, and controls innominate toxic swelling and other carbuncle sore.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of pulmonary alveolar proteinosis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing pulmonary alveolar proteinosis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of pulmonary alveolar proteinosis, it is characterized in that, by the medical material of following weight proportion, be prepared from: 15 parts of Ramulus et Folium Spiraeae Salicifolia, 12 parts, moth rattan, 12 parts of Herba Sedi Lineariss, two 10 parts of discrimination Anemone cathayensis Kitag. roots, 10 parts of GAMBIER, 12 parts of Abacopteris penangiana (Hook.) Chings, 14 parts of Flos Pyrethri tatsienensis, 18 parts of Kadsura interior, 8 parts of Rhizoma Dioscoreae Hypoglaucaes, Radix clerodendri yunnanensis spend 22 parts, to 20 parts of leaf oil Folium Cannabis, 16 parts of the bent tail moss of many capsules, 15 parts, fan blade rattan, 10 parts of Radix Thalictri elatis, 14 parts of Rhizoma Panacis bipinnatifidis, 16 parts of DAWANHUA, 12 parts, excrement ghost umbrella.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
The out-patient that inventor collects 98 routine pulmonary alveolar proteinosises between year November altogether in JIUYUE, 2010-2012, age 31-58 year, course of disease 1-4.Be divided at random: treatment group 91 examples, blank group 27 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal, observes more afterwards and has no recurrence for three months.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) | Untoward reaction example |
| Treatment group | 91 | 31（34.1%） | 37（40.6%) | 23（25.3%) | 74.7% | 0 |
| Blank group | 27 | 1(3.7%) | 3（11.1%） | 23（85.2%） | 14.8% | 0 |
Visible, the medicine that the present invention makes can safe and effective treatment pulmonary alveolar proteinosis.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
specific embodiment 1
Take: 15 grams of Ramulus et Folium Spiraeae Salicifolia, 12 grams, moth rattan, 12 grams of Herba Sedi Lineariss, two 10 grams of discrimination Anemone cathayensis Kitag. roots, 10 grams of GAMBIER, 12 grams of Abacopteris penangiana (Hook.) Chings, 14 grams of Flos Pyrethri tatsienensis, 18 grams of Kadsura interior, 8 grams of Rhizoma Dioscoreae Hypoglaucaes, Radix clerodendri yunnanensis spend 22 grams, to 16 grams of the bent tail moss of 20 grams of leaf oil Folium Cannabis, many capsules, 15 grams, fan blade rattan, 10 grams of Radix Thalictri elatis, 14 grams of Rhizoma Panacis bipinnatifidis, 16 grams of DAWANHUA, 12 grams, excrement ghost umbrella, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of pulmonary alveolar proteinosis.Oral, every bu is taken for twice sooner or later.
specific embodiment 2
Take: 15 grams of Ramulus et Folium Spiraeae Salicifolia, 12 grams, moth rattan, 12 grams of Herba Sedi Lineariss, two 10 grams of discrimination Anemone cathayensis Kitag. roots, 10 grams of GAMBIER, 12 grams of Abacopteris penangiana (Hook.) Chings, 14 grams of Flos Pyrethri tatsienensis, 18 grams of Kadsura interior, 8 grams of Rhizoma Dioscoreae Hypoglaucaes, Radix clerodendri yunnanensis spend 22 grams, to 16 grams of the bent tail moss of 20 grams of leaf oil Folium Cannabis, many capsules, 15 grams, fan blade rattan, 10 grams of Radix Thalictri elatis, 14 grams of Rhizoma Panacis bipinnatifidis, 16 grams of DAWANHUA, 12 grams, excrement ghost umbrella, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of pulmonary alveolar proteinosis.Oral, every bu is taken for twice sooner or later.
specific embodiment 3
Take: 15 grams of Ramulus et Folium Spiraeae Salicifolia, 12 grams, moth rattan, 12 grams of Herba Sedi Lineariss, two 10 grams of discrimination Anemone cathayensis Kitag. roots, 10 grams of GAMBIER, 12 grams of Abacopteris penangiana (Hook.) Chings, 14 grams of Flos Pyrethri tatsienensis, 18 grams of Kadsura interior, 8 grams of Rhizoma Dioscoreae Hypoglaucaes, Radix clerodendri yunnanensis spend 22 grams, to 16 grams of the bent tail moss of 20 grams of leaf oil Folium Cannabis, many capsules, 15 grams, fan blade rattan, 10 grams of Radix Thalictri elatis, 14 grams of Rhizoma Panacis bipinnatifidis, 16 grams of DAWANHUA, 12 grams, excrement ghost umbrella, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and according to this area common process, to granulate, packing, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of pulmonary alveolar proteinosis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. a Chinese medicine for the treatment of pulmonary alveolar proteinosis, it is characterized in that, by the medical material of following weight proportion, be prepared from: 15 parts of Ramulus et Folium Spiraeae Salicifolia, 12 parts, moth rattan, 12 parts of Herba Sedi Lineariss, two 10 parts of discrimination Anemone cathayensis Kitag. roots, 10 parts of GAMBIER, 12 parts of Abacopteris penangiana (Hook.) Chings, 14 parts of Flos Pyrethri tatsienensis, 18 parts of Kadsura interior, 8 parts of Rhizoma Dioscoreae Hypoglaucaes, Radix clerodendri yunnanensis spend 22 parts, to 20 parts of leaf oil Folium Cannabis, 16 parts of the bent tail moss of many capsules, 15 parts, fan blade rattan, 10 parts of Radix Thalictri elatis, 14 parts of Rhizoma Panacis bipinnatifidis, 16 parts of DAWANHUA, 12 parts, excrement ghost umbrella.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310649387.9A CN103599328B (en) | 2013-12-06 | 2013-12-06 | Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104543241A (en) * | 2014-12-30 | 2015-04-29 | 蓝照斓 | Ardisia villosa Roxb health tea |
| CN104940726A (en) * | 2015-07-02 | 2015-09-30 | 张金梅 | Traditional Chinese medicine preparation for pulmonary alveolar proteinosis and preparation method of traditional Chinese medicine preparation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1736435A (en) * | 2005-09-12 | 2006-02-22 | 陈沙 | Chinese medicinal preparation for treating rhinitis and preparation process thereof |
| CN103301210A (en) * | 2013-06-24 | 2013-09-18 | 周国生 | Traditional Chinese medicine for treating varicosity |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1736435A (en) * | 2005-09-12 | 2006-02-22 | 陈沙 | Chinese medicinal preparation for treating rhinitis and preparation process thereof |
| CN103301210A (en) * | 2013-06-24 | 2013-09-18 | 周国生 | Traditional Chinese medicine for treating varicosity |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104543241A (en) * | 2014-12-30 | 2015-04-29 | 蓝照斓 | Ardisia villosa Roxb health tea |
| CN104940726A (en) * | 2015-07-02 | 2015-09-30 | 张金梅 | Traditional Chinese medicine preparation for pulmonary alveolar proteinosis and preparation method of traditional Chinese medicine preparation |
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