CN103550514B - A kind of Chinese medicine treating chronic reflux nephropathy - Google Patents

A kind of Chinese medicine treating chronic reflux nephropathy Download PDF

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CN103550514B
CN103550514B CN201310504708.6A CN201310504708A CN103550514B CN 103550514 B CN103550514 B CN 103550514B CN 201310504708 A CN201310504708 A CN 201310504708A CN 103550514 B CN103550514 B CN 103550514B
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parts
herba
grams
radix
reflux nephropathy
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CN103550514A (en
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顾燕君
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Li Dequan
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Abstract

The present invention relates to a kind of Chinese medicine treating chronic reflux nephropathy, the medical material of following weight proportion be prepared from: hair connect 14 parts, Rhizoma Gymnadeniae 12 parts, Radix Solani Torvi 10 parts, Herba Lysimachiae Fortunei 10 parts, thorn coriander 8 parts, Herba pegani harmalae 8 parts, Radix seu folium cipakessae cinerascentis 12 parts, Gaster Sus domestica 14 parts, precipice Rhizoma Zingiberis Recens 14 parts, Fructus Ailanthi 16 parts, seed of Hygrophila saxatilis Ridl. 12 parts, Flos jasmini 10 parts, Radix Orthosiphonis Wulfenioidis 14 parts, Herba Thalictri elati 12 parts, Herba Cirrohopetali Andersonii 10 parts, Cacumen Securinegae Suffruticosae 14 parts。Clinical trial certificate, the present invention can safely and effectively treat chronic reflux nephropathy。

Description

A kind of Chinese medicine treating chronic reflux nephropathy
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine treating chronic reflux nephropathy。
Background technology
Chronic reflux nephropathy (chronicrefluxnephropathy), was called " atrophic pyelonephritis " in the past, was the one of interstitial kidney diseases。And dilatating and deformable, get involved cortex loose with the irregular thick cicatrix on kidney surface, renal calices pestle shape of getting involved wither shrink back, vesicoureteral reflux (VUR) is for feature。When detecting cicatrix, VUR is likely to indefinite, or VUR disappears。Some cases is characterized by repeatedly urinary tract infection (UTI), and owing to synulotic degree is different, renal damage can be limitation and diffusivity。The cause of disease of chronic reflux nephropathy is vesicoureteral reflux。Vesicoureteral reflux is under the urine reflux physiological conditions by unsound vesicoureteral junction, and the complete performance of anatomical function of the flap valve mechanism of ureter final stage prevents this reflux。
But chronic reflux nephropathy is still lacked at present to the effective medicine of generally recognized as safe。
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Hair is side, [source] Ranunculaceae Pheasant's-Eye Sichuan gold small cup even, with all herbal medicine。Summer gathers, and cleans, dries in the shade。[function cures mainly] heat clearing and damp drying, calm。For carbuncle sore tumefacting virus, conjunctival congestion and swelling pain, vomiting dysentery, cardiopalmus sleeplessness, epilepsy。
Rhizoma Gymnadeniae [source] is the tuber of the orchid family Rhizoma Gymnadeniae platymiscium Rhizoma Gymnadeniae。Autumn excavates, and removes stem and leaf and fibrous root, cleans, and puts into boiling in water to being degree without core white, pulls out and dry。[function cures mainly] the kidney invigorating and essence nourishing, regulating QI to relieve pain。Weak after being ill, neurasthenia, cough, sexual impotence, chronic diarrhea, leucorrhea, traumatic injury, congestion swells and ache。
Radix Solani Torvi [source] Solanaceae nightshade Radix Solani Torvi, is used as medicine with root。The whole year can adopt, and cleans and dries。[function cures mainly] dissipating blood stasis, stimulates the menstrual flow, detumescence, pain relieving, cough-relieving。Root: for traumatic injury stasis of blood pain, lumbar muscle strain, stomachache, toothache, amenorrhea, chronic cough。Fresh leaf: mash external application and can control innominate toxic swelling。
The false close net Cyclosorus plant Herba Lysimachiae Fortunei of Herba Lysimachiae Fortunei [source] Polypodiaceae, with all herbal medicine。Xia Qiu gathers, and cleans using fresh herb or dries。[function cures mainly] expelling wind and clearing away heat, eliminating damp, detoxifying。For infantile convulsion, cold cough, children's bronchopneumonia, laryngopharynx swelling and pain, tonsillitis, heatstroke is suffered from abdominal pain, dysentery, diarrhoea, urinary system infection, bones and muscles pain;Carbuncle furuncle, furuncle, venom are controlled in external。
Thorn coriander [source] Umbelliferae thorn coriander platymiscium thorn coriander, with all herbal medicine。Xia Qiucai, dries in the shade or using fresh herb。[function cures mainly] dispelling wind is antipyretic, stomach invigorating。For catching a cold, measles is caved in, tracheitis, enteritis, diarrhoea, acute infectious hepatitis;Treating swelling and pain by traumatic injury is controlled in external。
Herba pegani harmalae [source] zygophyllaceae Peganum Three Plants Herba pegani harmalae PeganumharmalaL., is used as medicine with herb and seed。Xia Qiucai herb, adopts during seed maturity, dries or using fresh herb。[function cures mainly] lung qi dispersing cough-relieving, wind-damp dispelling, removing toxic substances。Son: cough and asthma。Herb: innominate toxic swelling, rheumatic arthritis are controlled in external。
Radix seu folium cipakessae cinerascentis [source] Meliaceae Cipadessa baecifera Miq platymiscium gray wool Cipadessa baecifera Miq., it is used as medicine with root, leaf。Root can be adopted the whole year, and section is dried。Ye Xiaqiucai, using fresh herb or dry in the shade。[function cures mainly] heat-clearing and toxic substances removing, circulation of qi promoting relieving constipation, preventing the attack (or recurrence) of malaria。For catching a cold, heating is not moved back, malaria, constipation, stomachache, dysentery, rheumatic arthritis;Children's's dermatitis, skin pruritus, burn and scald are controlled in external。
Gaster Sus domestica [source] Compositae wild carraway platymiscium Cacalia tangutica is used as medicine with underground tuber。Excavate after autumn end Seedling is withered, clean and dry。[function cures mainly] dispels the wind, and reduces phlegm, suppressing the hyperactive liver。For dizziness of having a headache, rheumatalgia, hemiplegia, cough with copious phlegm。
Ginger precipice, precipice Rhizoma Zingiberis Recens [source] fern Polypodiaceae precipice Rhizoma Zingiberis Recens, is used as medicine with root stock。Spring and summer gathers, unhairing, cleans section, dries。[function cures mainly] expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral。For rheumatalgia, traumatic injury, fracture, otitis media。
Fructus Ailanthi [source] this product is the fruit of quassia ailanthus altissima (mill.) swingle。The fruit picking of autumn end, dries。[function cures mainly] clearing away heat and promoting diuresis, pain relieving, hemostasis。For having a stomachache, have blood in stool, hematuria;Trichomonas vaginitis is controlled in external。
The seed of seed of Hygrophila saxatilis Ridl. [source] Acanthaceae Hygrophila phytolith Hygrophila salicifolia。[function cures mainly] spasmolytic pain relieving。For demented, twitch, asthma, stomachache。Carbuncle, malignant boil are controlled in external。
Flos jasmini [source] Oleaceae Flos Jasmini Sambac platymiscium Flos jasmini. it is used as medicine with Herb。The whole year can adopt, and dries or using fresh herb。[function cures mainly] circulation of qi promoting menstruction regulating and pain relieving, heat clearing away eliminating stagnation。For having a stomachache, hepatitis, menoxenia, dysmenorrhea, leukorrhagia, stomatitis, skin itching, orchitis, mastitis, tuberculous lymphadenitis。
Radix Orthosiphonis Wulfenioidis [source] Labiatae Radix Orthosiphonis Wulfenioidis platymiscium Radix Orthosiphonis Wulfenioidis, is used as medicine with root。Xia Qiu gathers, and cleans and dries。[function cures mainly] dispels the wind diuresis, and analgesiaization is amassed, synthetism granulation promoting。For food stagnation, vasculitis, nephritis, cystitis, lithangiuria, rheumatalgia;Traumatic injury is controlled in external, fracture。
The herb of Herba Thalictri elati [source] Ranunculaceae Fortune Meadowrue Herb platymiscium Herba Thalictri elati。Xia Qiu gathers, and cleans and dries。[function cures mainly] heat-clearing and toxic substances removing, arresting convulsion, removing food stagnancy。For infantile pneumonia, infantile convulsion, infantile malnutrition。
Herba Cirrohopetali Andersonii [source] the orchid family volume lobe epidendrum comb cap volume lobe orchid CirrhopetalnmandersoniiHook.f., with all herbal medicine。The four seasons can adopt, using fresh herb or dry。[function cures mainly] expelling wind and removing dampness, invigorates blood circulation, and cough-relieving helps digestion long-pending。For traumatic injury, human female is empty, infantile cough, pertussis。
Cacumen Securinegae Suffruticosae [source] is Euphorbiaceae phyllanthus emblica platymiscium Cacumen Securinegae Suffruticosae PhyllanthusurinariaL., with all herbal medicine。Xia Qiu gathers herb, decontamination, dries。[function cures mainly] clearing away heat and promoting diuresis, improving eyesight, removing food stagnancy。For oedema due to nephritis, urinary system infection, calculus, enteritis, dysentery, young waiter in a wineshop or an inn's infantile malnutrition, eye keratitis, icterohepatitis;External is controlled Trimeresurus stejnegeri and is bitten。
Summary of the invention
It is desirable to provide a kind of Chinese medicine treating chronic reflux nephropathy, by selecting suitable medical material and proportioning thereof, reach safely and effectively to cure the purpose of chronic reflux nephropathy。
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine treating chronic reflux nephropathy, it is characterized in that, the medical material of following weight proportion be prepared from: hair connect 14 parts, Rhizoma Gymnadeniae 12 parts, Radix Solani Torvi 10 parts, Herba Lysimachiae Fortunei 10 parts, thorn coriander 8 parts, Herba pegani harmalae 8 parts, Radix seu folium cipakessae cinerascentis 12 parts, Gaster Sus domestica 14 parts, precipice Rhizoma Zingiberis Recens 14 parts, Fructus Ailanthi 16 parts, seed of Hygrophila saxatilis Ridl. 12 parts, Flos jasmini 10 parts, Radix Orthosiphonis Wulfenioidis 14 parts, Herba Thalictri elati 12 parts, Herba Cirrohopetali Andersonii 10 parts, Cacumen Securinegae Suffruticosae 14 parts。
Below in conjunction with clinical laboratory data, beneficial effects of the present invention is described:
1, physical data
Inventor collects the out-patient of 95 example chronic reflux nephropathy-2011 years in June, 2008 altogether between JIUYUE, age 21-60 year, course of disease 1-5。It is randomly divided into: treatment group 75 example, blank group 20 examples。Two groups of data such as age, the state of an illness there was no significant difference, and has comparability。
2, test method
The capsule that the oral present invention specific embodiment 1 of 2.1 treatment groups prepares, sooner or later respectively once。15 days courses for the treatment of。
2.2 blank group oral placebo capsules, sooner or later respectively once。15 days courses for the treatment of。
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal。Taking a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or normal。Invalid: clinical symptoms is without being clearly better or increasing the weight of。
3.2 treatment statistical results are in Table 1。
1 liang of table group comparitive study
Group n Recovery from illness Take a turn for the better Invalid Untoward reaction example Total effective rate (%)
Treatment group 75 16 (21.3%) 38 (50.7%) 21 (28%) 0 72%
Blank group 20 0 5 (25%) 15 (75%) 0 25%
Visible, chronic reflux nephropathy can safely and effectively be controlled by the medicine that the present invention prepares。
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment。
Specific embodiment 1
Weigh: hair connect 14 grams, Rhizoma Gymnadeniae 12 grams, Radix Solani Torvi 10 grams, Herba Lysimachiae Fortunei 10 grams, thorn coriander 8 grams, Herba pegani harmalae 8 grams, Radix seu folium cipakessae cinerascentis 12 grams, Gaster Sus domestica 14 grams, precipice Rhizoma Zingiberis Recens 14 grams, Fructus Ailanthi 16 grams, seed of Hygrophila saxatilis Ridl. 12 grams, Flos jasmini 10 grams, Radix Orthosiphonis Wulfenioidis 14 grams, Herba Thalictri elati 12 grams, Herba Cirrohopetali Andersonii 10 grams, Cacumen Securinegae Suffruticosae 14 grams, add 8 times amount water, decoct 1.5 hours, filter;Filtering residue adds 6 times amount water, decocts 1 hour, filters;Merging filtrate, concentration, dry, load capsule shells, the capsule of 1 day consumption of adult normal must be met。
For treating chronic reflux nephropathy。Oral, every bu is taken for twice sooner or later。
Specific embodiment 2
Weigh: hair connect 14 grams, Rhizoma Gymnadeniae 12 grams, Radix Solani Torvi 10 grams, Herba Lysimachiae Fortunei 10 grams, thorn coriander 8 grams, Herba pegani harmalae 8 grams, Radix seu folium cipakessae cinerascentis 12 grams, Gaster Sus domestica 14 grams, precipice Rhizoma Zingiberis Recens 14 grams, Fructus Ailanthi 16 grams, seed of Hygrophila saxatilis Ridl. 12 grams, Flos jasmini 10 grams, Radix Orthosiphonis Wulfenioidis 14 grams, Herba Thalictri elati 12 grams, Herba Cirrohopetali Andersonii 10 grams, Cacumen Securinegae Suffruticosae 14 grams, add 8 times amount water, decoct 1.5 hours, filter;Filtering residue adds 6 times amount water, decocts 1 hour, filters;Merging filtrate, concentration, dry, pulverize, the powder of 1 day consumption of adult normal must be met。
For treating chronic reflux nephropathy。Oral, every bu is taken for twice sooner or later。
Specific embodiment 3
Weigh: hair connect 14 grams, Rhizoma Gymnadeniae 12 grams, Radix Solani Torvi 10 grams, Herba Lysimachiae Fortunei 10 grams, thorn coriander 8 grams, Herba pegani harmalae 8 grams, Radix seu folium cipakessae cinerascentis 12 grams, Gaster Sus domestica 14 grams, precipice Rhizoma Zingiberis Recens 14 grams, Fructus Ailanthi 16 grams, seed of Hygrophila saxatilis Ridl. 12 grams, Flos jasmini 10 grams, Radix Orthosiphonis Wulfenioidis 14 grams, Herba Thalictri elati 12 grams, Herba Cirrohopetali Andersonii 10 grams, Cacumen Securinegae Suffruticosae 14 grams, add 8 times amount water, decoct 1.5 hours, filter;Filtering residue adds 6 times amount water, decocts 1 hour, filters;Merging filtrate, concentration, dry, add appropriate dextrin and correctives, granulate according to this area common process, packaging, can be prepared by meeting the granule of 1 day consumption of adult normal。
For treating chronic reflux nephropathy。Oral, every bu is taken for twice sooner or later。

Claims (1)

1. the Chinese medicine treating chronic reflux nephropathy, it is characterized in that, the medical material of following weight proportion be prepared from: hair connect 14 parts, Rhizoma Gymnadeniae 12 parts, Radix Solani Torvi 10 parts, Herba Lysimachiae Fortunei 10 parts, thorn coriander 8 parts, Herba pegani harmalae 8 parts, Radix seu folium cipakessae cinerascentis 12 parts, Gaster Sus domestica 14 parts, precipice Rhizoma Zingiberis Recens 14 parts, Fructus Ailanthi 16 parts, seed of Hygrophila saxatilis Ridl. 12 parts, Flos jasmini 10 parts, Radix Orthosiphonis Wulfenioidis 14 parts, Herba Thalictri elati 12 parts, Herba Cirrohopetali Andersonii 10 parts, Cacumen Securinegae Suffruticosae 14 parts。
CN201310504708.6A 2013-10-23 2013-10-23 A kind of Chinese medicine treating chronic reflux nephropathy Expired - Fee Related CN103550514B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1343504A (en) * 2000-09-15 2002-04-10 孔文舟 Composite medicine for treating nephrosis and its preparing process
CN1973864A (en) * 2006-08-31 2007-06-06 胡瑞 Medicine composition for treating hematuria and nephropyelitis and its prepn
CN102451458A (en) * 2010-10-27 2012-05-16 赵传利 Traditional Chinese medicine formula for treating chronic pyelonephritis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1343504A (en) * 2000-09-15 2002-04-10 孔文舟 Composite medicine for treating nephrosis and its preparing process
CN1973864A (en) * 2006-08-31 2007-06-06 胡瑞 Medicine composition for treating hematuria and nephropyelitis and its prepn
CN102451458A (en) * 2010-10-27 2012-05-16 赵传利 Traditional Chinese medicine formula for treating chronic pyelonephritis

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