CN103202899B - Traditional Chinese medicine feed additive for preventing and curing livestock and poultry diarrhea - Google Patents

Traditional Chinese medicine feed additive for preventing and curing livestock and poultry diarrhea Download PDF

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CN103202899B
CN103202899B CN201310110309.1A CN201310110309A CN103202899B CN 103202899 B CN103202899 B CN 103202899B CN 201310110309 A CN201310110309 A CN 201310110309A CN 103202899 B CN103202899 B CN 103202899B
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traditional chinese
chinese medicine
feed additive
parts
days
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CN103202899A (en
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张磊
陈鹏举
侯金丽
周红杰
孙淼淼
韩斐
蔡珍珍
解金辉
郜许普
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HENAN BIYUNTIAN FEED Co Ltd
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Abstract

The invention belongs to the technical field of traditional Chinese medicine feed additives, and in particular relates to a traditional Chinese medicine feed additive for preventing and curing livestock and poultry diarrhea. The traditional Chinese medicine feed additive mainly comprises the following traditional Chinese medicinal materials in parts by weight: 10-20 parts of jasmine, 15-25 parts of dandelion, 15-20 parts of root of common peony and 10-15 parts of astragalus mongholicus. The traditional Chinese medicine feed additive for preventing and curing livestock and poultry diarrhea provided by the invention has the efficacies of clearing away heat, purging pathogenic fire, detoxifying, dissipating blood stasis and the like, has obvious effects of preventing and curing livestock and poultry diarrhea, also can effectively prevent milk resistance, medicament residues and food safety issues, and is suitable for being popularized in animal production.

Description

The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea
Technical field
The invention belongs to veterinary drug technical field, particularly a kind of Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea.
Background technology
Along with the fast development of Chinese national economy and the raising day by day of living standards of the people, urban and rural residents not only to animal products as the demand such as meat, egg, milk and livestock and poultry product (boil as smoked intestines class, smoked boil ham, sauce spiced and stewed food, pickled and cured meat, milk powder) obviously rises, and the quality requirement of animal products is improved constantly, as required product safety, green, drug residue free, nuisanceless etc.For meeting the vigorous market demand; the livestock and poultry breeding industry of China is constantly developed; breeding environment constantly worsens simultaneously; disease incident is more and more higher; a large amount of medicines adds causes animal products quality security problem to become increasingly conspicuous; the public brought thus is to the trust crisis of animal products quality safety, and the development of also continuing to China's animal husbandry science causes and has a strong impact on.
Livestock and poultry diarrhea is (as bacterial diarrhoea of bacterial disease such as colibacillosis, salmonellosis, duck infectious serositis; The diarrhoea that the virosis such as ewcastle disease, influenza, transmissible gastroenteritis cause, and the diarrhoea etc. that stress cause) and fur-bearing animal diarrhoea etc. sporadic for many years popular in many provinces and regions of China, bring larger economic loss to China's aquaculture.
Because cause the reason a lot (as many factors such as virus infections, bacteriological infection, water pollution, feed mold, environmental factor, temperature great changes) of diarrhoea, treatment difficulty is caused to strengthen, add clinical in a large amount of abuse of antibiotics and blindly add the measure prevention and therapy such as antiviral agent, cause of disease is caused to produce the serious resistance to the action of a drug to these medicines, result for the treatment of is day by day not remarkable, the more important thing is that these medicines easily remain, harm humans is healthy, causes livestock and poultry and fur-bearing animal diarrhoea prevention and therapy medicine to occur blank.At present, diarrhoea still lacks the Chinese herbal feed additive of good prevention and therapy clinically, therefore urgently develops a kind of Chinese herbal feed additive of safe and reliable prevention and therapy diarrhoea to meet the demand of actual production.
Summary of the invention
The object of the present invention is to provide a kind of Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea.
The technical solution used in the present invention is as follows:
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, the Chinese medicine primarily of following weight portion forms: cape jasmine 10-20 part, dandelion 15-25 part, radix paeoniae rubrathe 15-20 part, Radix Astragali 10-15 part.
Further, with parts by weight, described feed addictive also comprises: coptis 10-20 part, root of large-flowered skullcap 10-15 part, golden cypress 10-15 part, mother chrysanthemum 10-15 part, selfheal 15-20 part, thick wood-fern rhizome 10-15 part, lophatherum gracile 10-15 part, moutan bark 10-15 part.
Belong to heat symptoms caused by an exopathgen from the dialectical diarrhoea of Chinese veterinarian's angle and be full of three burnt, the real hot or damp and hot illnesss of internal organs, therefore the fire of three Jiao in side, is rushed down clearly with cape jasmine, diuresis, behavior main ingredient under heat conduction, the clear purge the sthenic heart-fire of the coptis, the fire of double clear middle Jiao, the clear part of the body cavity above the diaphragm housing the heart and lungs lung-fire of the root of large-flowered skullcap, golden cypress rushes down the fire of part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels liver kidney, dandelion, mother chrysanthemum, lophatherum gracile, rhizome of cyrtomium, selfheal, moutan bark etc. are clearing heat and detoxicating is adjuvant, the analgesia of radix paeoniae rubrathe clearing heat and cooling blood, promoting blood circulation to remove blood stasis, dysmenorrhoea is adjutant, and the righting of Radix Astragali benefit gas, myogenic, the removing toxic substances of holder sore are for making medicine.All medicines share, and play the effect of clearing heat-fire, removing toxic substances, antibacterial, anti-inflammatory altogether, have antiviral efficacy.
The present invention is clinical in preventing bird (as chicken, duck, goose, quail, dove etc.), the greatly diarrheal disease such as animal (as pig, ox, sheep, donkey, camel etc.) and fur-bearing animal (nursing, recoon dog, ermine, rabbit etc.) all to have good curative effect, and total effective rate is more than 97%; If be used for the treatment of, when using the technical scheme of claim 1 and 2, evident in efficacy, efficiently can be reached for 92.6%, 93.8% respectively.
Chinese herbal feed additive of the present invention, regulates using dosage can prevent or treat the diarrhoea of livestock and poultry and fur-bearing animal significantly, and during as prevention, general addition is the 0.4-0.6% of feeding quality; If treatment diarrhoea, using dosage is 0.5%-1.5%.During use, after said medicine is pulverized, cross 300 mesh sieves, obtain powder.Scale livestock farming can adopt spice mixed feeding method, and raising family scattered both can spice mixed feeding, also powder decocting can be got juice drinking-water, also can gavage.Chinese herb feed additive of the present invention is pure tcm product, can effectively avoid anti-milk, medicament residue and food-safety problem, various formulation (as powder, oral liquid, granule, tablet, pill, paste etc.) can be processed into simultaneously, be suitable for promoting in husbandry sector.
The present invention, relative to prior art, has following advantage:
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea provided by the present invention, there is the effects such as clearing heat-fire, removing toxic substances, the loose stasis of blood, prevention and therapy livestock and poultry diarrhea Be very effective, and can effectively avoid anti-milk, medicament residue and food-safety problem, be suitable for promoting in husbandry sector.
Detailed description of the invention
With specific embodiment, technical scheme of the present invention is described below, but protection scope of the present invention is not limited thereto:
Embodiment 1
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, its weight portion is composed as follows:
Cape jasmine 15 parts, dandelion 20 parts, the radix paeoniae rubrathe 17.5 parts, the Radix Astragali 12.5 parts.
All medicine pulverizations are crossed 300 mesh sieves, obtains powder.
Embodiment 2
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, its weight portion is composed as follows:
Cape jasmine 10 parts, dandelion 15 parts, the radix paeoniae rubrathe 15 parts, the Radix Astragali 10 parts.
All medicine pulverizations are crossed 300 mesh sieves, obtains powder.
Embodiment 3
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, its weight portion is composed as follows:
Cape jasmine 20 parts, dandelion 25 parts, the radix paeoniae rubrathe 20 parts, the Radix Astragali 15 parts.
All medicine pulverizations are crossed 300 mesh sieves, obtains powder.
Embodiment 4
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, it is composed as follows:
Cape jasmine 15g, dandelion 20g, radix paeoniae rubrathe 17.5g, Radix Astragali 12.5g, coptis 15g, root of large-flowered skullcap 12.5g, golden cypress 12.5g, mother chrysanthemum 12.5g, selfheal 17.5g, thick wood-fern rhizome 12.5g, lophatherum gracile 12.5g, moutan bark 12.5g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 5
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, it is composed as follows:
Cape jasmine 10g, dandelion 15g, radix paeoniae rubrathe 15g, Radix Astragali 10g, coptis 10g, root of large-flowered skullcap 10g, golden cypress 10g, mother chrysanthemum 10g, selfheal 15g, thick wood-fern rhizome 10g, lophatherum gracile 10g, moutan bark 10g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 6
The Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, it is composed as follows:
Cape jasmine 20g, dandelion 25g, radix paeoniae rubrathe 20g, Radix Astragali 15g, coptis 20g, root of large-flowered skullcap 15g, golden cypress 15g, mother chrysanthemum 15g, selfheal 20g, thick wood-fern rhizome 15g, lophatherum gracile 15g, moutan bark 15g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Effect example:
Embodiment 1 additive spice is taken orally: the large domestic animal such as ox, horse and camel: 150-300g/ head; Pig, sheep: 50-100g/ head, only, only, bird: 1-3g/ only, adds up effect after being used in conjunction 5 days to rabbit: 6-12g/ to fox, racoon dog, ermine: 15-30g/.Preventive dose reduces by half.
Efficacy determination: during prevention, protective rate is considered as effectively more than 96%.During treatment, take medicine 5, symptom of diarrhea is eliminated, and in 7 days not repeatedly, is considered as curing; In 10 days, without symptom of diarrhea, be considered as effectively, otherwise be considered as invalid.
Concrete effect is prevented in Table 1() and table 2(treatment):
Table 1
Table 2
Embodiment 4 additive spice is taken orally: the large domestic animal such as ox, horse and camel: 150-300g/ head; Pig, sheep: 50-100g/ head, only, only, bird: 1-3g/ only, or according to 0.4%-1.5% spice mixed feeding, adds up curative effect after being used in conjunction 5 days to rabbit: 6-12g/ to fox, racoon dog, ermine: 15-30g/.Preventive dose reduces by half.
Efficacy determination: during prevention, protective rate is considered as effectively more than 96%.Take medicine during treatment 5, symptom of diarrhea is eliminated, and in 7 days not repeatedly, is considered as curing; In 10 days, without symptom of diarrhea, be considered as effectively, otherwise invalid.Effect refers to table 3(prevention) and table 4(treatment).
Table 3
Table 4
Concrete case 1
In February, 2011, the pig farm of Jiaozuo City Boai County Zhao extracts 8 nests out at random with the piglet 94 of age in days with pig house, test group 48, control group 46, test number of days 20 days, period test group and control group except conveniently yard feeding pattern raising, immunity inoculation, sterilization etc., the Chinese medicine composition of Example 1 is pulverized, and crosses 300 mesh sieves, test group is according to 30g/ head, make an addition to feed and make particle after mixing, weaning and bring into use for first 4 days, be used in conjunction 7 days.Period, test group 48 piglets have 1 pig to occur mild diarrhea, and the incidence of disease is 2.08%, and efficient 97.92%, morbidity pig is according to 50g/ head, and decocting is got juice and gavaged, and once a day, is used in conjunction 3, recovery from illness.5 are had to occur diarrhoea, the incidence of disease 10.86% in control group 46 piglets.According to 50g/ head after morbidity, decocting is got juice and is gavaged, and once a day, is used in conjunction 5, and simultaneously fluid infusion salt is used in conjunction 3 days, and wherein 2 serious sick pigs adopt mequindox injection intramuscular injection to carry out treatment 3 days, fully recover after 5 days.Test confirms: chemoprophylaxis of the present invention and treatment diarrhea of weaned piglets Be very effective.
Concrete case 2
In November, 2009,15000 laying hens that Liangyuan District, Shangqiu Lee raises, randomly draw 600 and are divided into test group and control group, and except conveniently raisings, immunity inoculation, sterilization etc., the Chinese medicine composition of Example 4 is pulverized, mistake 300 mesh sieves.
To suffer from diarrhoea occurrence regularity according to this laying hen, generally suffer from diarrhoea during 100 age in days to 125 ages in days, therefore test group is from 95 ages in days, is added into feed according to 0.6% ratio in the past, mixes rear for chicken free choice feeding, is used in conjunction 10 days.
Preventive effect is observed: duration of test, control group chicken group the dead chicken 28 of 95 to 145 age in days internal causes diarrhoea, the death rate 9.33%; Test group is none death in 95 to 145 ages in days.
Concrete case 3
In December, 2010, piglet about Zhongmou County Wang buys 320 70 ages in days from other places occurs that spirit is depressed, poor appetite, vomiting, diarrhoea, and between ight soil or have blood or come to mucous membrane tissue fragment etc., to fall ill in 3 days dead 37, case fatality rate is 11.56%.Cuing open inspection, to be changed to small intestinal mucosa and mesenterium congested, hemorrhage, dilatation of intestine, in be full of yellow liquid, intestinal villi shortens, and severe one Villus atrophy, even disappears; Colorectal mucosa generation Catarrhal, hemorrhagic enteritis, colon and the swelling of caecum mucous membrane, above with mucus, clot and fibrinous exudate etc.Swine dysentery and epidemic diarrhea mixed infection is diagnosed as through clinical symptoms, pathological change and laboratory diagnosis.
The Chinese medicine composition of Example 5 is pulverized, cross 300 mesh sieves, test group is according to 90g/ head, decocting is got juice and is gavaged, every day 1 time, serve on 5, dregs of a decoction spice, simultaneously fluid infusion salt drinking-water is used in conjunction 3 days, and wherein 19 serious piglets coordinate berberine sulphate parenteral solution, mequindox injection and interferon intramuscular injection (dosage uses to specifications), every day 1 time, be used in conjunction 3 days, after 5 days, symptom of diarrhea disappears substantially, during medication, in 19 serious pigs 4 because of outside dehydration Serious Mortality, then none piglet death; Do not occur Relapse rate in 7 days, in 10 days, piglet has no symptom of diarrhea, and recovery from illness, after 15 days, pig grows fine, and each side is normal.
Concrete case 4
In December, 2011,5000 large-scale white meat-type chickens of block that Suburb of Zhengzhou Zou raises, at 29 ages in days, occur that ight soil is thin in water sample, occasionally have yellow, white, green ight soil, there is undergrowth in serious broiler chicken, body is become thin, hat whisker turns white, and falls ill after 3 days, and chicken starts to occur death; Chicken intestinal mucosa of dying of illness is congested, hemorrhage, come off, and intestines wall is thinning, and cloaca is hemorrhage, interior just like watery yellow-white ight soil etc.The Chinese medicine composition of Example 6 is pulverized, is crossed 300 mesh sieves and mix; Get this powder by 0.8% of material feeding amount to boil water, liquid medicine is drunk water, dregs of a decoction spice, and after being used in conjunction 5 days, symptom disappears substantially, does not occur Relapse rate in 7 days, and disease must heal, and during medication, none example is dead; Symptom of diarrhea is not found in 10 days.
Concrete case 5
In June, 2011, there is diarrhoea at 31 ages in days in 11000 quails that Ruzhou City Zhang raises, ight soil is thin, and color mostly is yellowish-white, green excrement, also shows yellow butyrous ight soil, serious quail body is become thin, dehydration, claw is dry, falls ill and occurs death after 3 days, the quail died of illness cut open inspection change multilist present intestinal mucosa congested, hemorrhage, come off, intestines wall is thinning, and cloaca is hemorrhage, interior just like watery yellow-white ight soil etc.
The Chinese medicine composition pulverizing of Example 2,300 mesh sieves excessively, add feed according to 0.8% ratio and after mixing, free choice feeding, is used in conjunction 5 days; Add Sodamint electrolytic salt and VC in drinking-water, be used in conjunction 2 days.After being used in conjunction 5 days, symptom of diarrhea disappears substantially, does not occur the diseases such as diarrhoea in 10 days, and disease must heal, and is total to dead 426, the death rate 3.87% during medication.
Concrete case 6
On March 11st, 2012, the piglet 136 raised in Kaifeng southern suburbs Cao pig house, piglet is suffered from diarrhoea suddenly, discharge milky or linen pulpous state, pasty state stickiness ight soil, then sick pig occurs that spirit is tired, by hair slightly disorderly, body surface is unglazed, anorexia, weakness of limbs, walking is unstable or sleeping ground is difficult rises, and ight soil is canescence stench, slack anus, fecal incontinence, become thin, dewater, indivedual pig extremely feeble and dead, the death rate 5.15%.Pathological change is that sick dead pig corpse is become thin, and mucous membrane is pale, anus and around faecal contamination, and intestinal mucosa is catarrhal inflammation, and intestines wall is thinning, has milky or canescence pasty state or ointment shape content, lymphonodi mesenterici mild swelling etc. in colon.Through clinical symptoms, pathological change and laboratory diagnosis, be diagnosed as the white scour of piglet.
The Chinese medicine composition of Example 3 is pulverized, cross 300 mesh sieves, test group is according to 50g/ head, and decocting is got juice and gavaged, once a day, serve on 5, the salt of fluid infusion simultaneously drinking-water is used in conjunction 3 days, and after 5 days, symptom disappears substantially, Relapse rate is not there is in 10 days, recovery from illness, except 2 piglets are because of except serious dehydration death during medication, more dead without piglet.
Above-described embodiment is the preferred embodiment of the present invention, but embodiments of the present invention are not restricted to the described embodiments, and the change that other any the present invention of not deviating from does all should be equivalent substitute mode, is included within protection scope of the present invention.

Claims (1)

1. the Chinese herbal feed additive of prevention and therapy livestock and poultry diarrhea, it is characterized in that, be made up of the Chinese medicine of following weight portion: cape jasmine 10-20 part, dandelion 15-25 part, radix paeoniae rubrathe 15-20 part, Radix Astragali 10-15 part, coptis 10-20 part, root of large-flowered skullcap 10-15 part, golden cypress 10-15 part, mother chrysanthemum 10-15 part, selfheal 15-20 part, thick wood-fern rhizome 10-15 part, lophatherum gracile 10-15 part, moutan bark 10-15 part.
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CN103766656B (en) * 2014-01-22 2015-04-15 中国科学院东北地理与农业生态研究所 Feed additive for relieving stress of piglets and preparation method thereof
CN103907566A (en) * 2014-04-14 2014-07-09 湖南农业大学 Method for assisting in cultivating Yuanbao chicken by aid of traditional Chinese medicinal materials
CN104000049B (en) * 2014-06-17 2016-04-06 临沂大学 A kind of composition and application thereof preventing and treating lamb dysentery
CN105831392B (en) * 2015-01-16 2020-12-22 北京大北农科技集团股份有限公司 Pig feed additive and feed thereof
CN105494928A (en) * 2015-12-03 2016-04-20 闫冷 Feed additive for treating diarrhea of pigeons
CN107173609A (en) * 2017-05-25 2017-09-19 乐清益昌食品技术有限公司 A kind of Chinese herbal feed additive for being used to prevent and treat poultry diarrhea

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Inventor after: Zhang Lei

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