CN103202909B - Traditional Chinese medicine feed additive for preventing and curing diarrhea of livestock and poultry as well as fur-bearing animals - Google Patents
Traditional Chinese medicine feed additive for preventing and curing diarrhea of livestock and poultry as well as fur-bearing animals Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine feed additive for preventing and curing diarrhea of livestock and poultry as well as fur-bearing animals, which belongs to the technical field of traditional Chinese medicine feed additives. The traditional Chinese medicine feed additive mainly comprises the following traditional Chinese medicines in parts by weight: 10-20 parts of coptis chinensis, 15-25 parts of golden cypress, 10-20 parts of moutan bark, 15-20 parts of root of common peony, 10-20 parts of mother chrysanthemum and 10-15 parts of astragalus mongholicus. The traditional Chinese medicine feed additive not only can prevent diarrhea of livestock and poultry, but also has an obvious therapeutic effect, is similarly effective to fur-bearing animals, is a pure traditional Chinese medicine, can effectively prevent problems of milk resistance, medicament residues and poor food safety, and is suitable for being popularized in animal production.
Description
Technical field
The invention belongs to veterinary drug technical field, particularly a kind of Chinese herbal feed additive preventing and treating livestock and poultry and fur-bearing animal diarrhoea.
Background technology
Along with China's living standard of urban and rural population level improves constantly, and the raising of people's environmental consciousness and Consciousness of food security, livestock and poultry product quality requirement is improved constantly, increasingly stringent is required to food-safety problem.As required product safety, green, drug residue free, nuisanceless etc., and medicament residue affects meat, egg, the key factor of the animal products safety such as milk, and human body often takes in the left drugs such as the antibiotic of low dosage, can accumulate in vivo gradually and cause various organ generation pathology, produce allergy, allergic reaction, immunosupress etc., final harm humans is healthy, especially nearest 2012 CCTV1, the events such as numerous media unit exposure such as CCTV13 and Focus fast-growing chicken and false veterinary drug cause great disturbance in the industry, the problem of food security is day by day white-hot, the development that will continue to China's animal husbandry science causes and has a strong impact on.
The problem of medicament residue has restricted the development of industry, and the problem of livestock and poultry diarrhea carrys out huge economic loss to cultivation industrial belt, has become the important problem of serious threat intensive animal husbandry development.Cause the reason of diarrhoea numerous in (as virus infections as everyone knows, bacteriological infection, water pollution, feed mold, environmental factor, the many factors such as temperature great change), add along with cultivation scale constantly expands, breeding environment worsens increasingly, and disease is multiple, and death rate is high, the measure such as abuse of antibiotics and antiviral chemical drug causes cause of disease to produce the serious resistance to the action of a drug to these medicines, result for the treatment of is day by day not remarkable, increases the weight of the difficulty of antibiotic research and development, and the antimicrobial for the treatment of diarrhoea at present has kind more than 200, but due to Long-Time Service, pig avian escherichia coli, the resistant rate of salmonella etc. is very high, and its curative effect significantly declines even invalid, and drug-fast bacteria is the trend of multidrug resistant and crossing drug resistant, and namely drug-fast bacteria is to PCs, cephalosporins, FQNS, aminoglycoside, Florfenicol, compound sulfonamide medicine is also in resistance, add clinical in a large amount of abuse of antibiotics, even use human drugs, cause drug resistance problems day by day serious, result for the treatment of is day by day not remarkable, increase the weight of the difficulty of antibiotic research and development, be meanwhile used for the treatment of virus and cause the chemicals of diarrhoea as far back as U.S. FDA in 2006, amantadine is forbidden in the dispatch of the Ministry of Agriculture of China, Rimantadine, ACV, morpholine (two) guanidine (moroxydine), the chemical antiviral medicines such as Ribavirin, cause the medicine of control diarrhoea to occur blank, therefore urgently develop a kind of safety, the Chinese herbal feed additive of reliable control diarrhoea is to meet the demand of actual production.
Summary of the invention
The object of the present invention is to provide a kind of Chinese herb feed additive preventing and treating livestock and poultry and fur-bearing animal diarrhoea.
For solving the problems of the technologies described above, the technical scheme that the present invention takes is:
The Chinese herbal feed additive of control livestock and poultry and fur-bearing animal diarrhoea, primarily of following weight portion Chinese medicine composition: coptis 10-20 part, golden cypress 15-25 part, moutan bark 10-20 part, radix paeoniae rubrathe 15-20 part, mother chrysanthemum 10-20 part, Radix Astragali 10-15 part.
Further, with parts by weight, also comprise: root of large-flowered skullcap 10-15 part, selfheal 15-20 part, thick wood-fern rhizome 10-15 part, lophatherum gracile 10-15 part, cordate houttuynia 10-20 part.
Suffer from diarrhoea from Chinese veterinarian's angle dialectical genus heat symptoms caused by an exopathgen and be full of three burnt, the real hot or damp and hot illnesss of internal organs.Therefore with the clear purge the sthenic heart-fire of the coptis in side, hold concurrently clear in the fire of Jiao, the fire that golden cypress rushes down part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels liver kidney is main ingredient, and mother chrysanthemum, the root of large-flowered skullcap, selfheal, thick wood-fern rhizome, lophatherum gracile just, cordate houttuynia is clearing heat and detoxicating is adjuvant.Radix paeoniae rubrathe clearing heat and cooling blood, promoting blood circulation to remove blood stasis, dysmenorrhoea is eased pain, and moutan bark taste is pungent cold in nature, function clearing heat and cooling blood, and controlling the blood stasis of blood of faling apart is adjutant, the righting of Radix Astragali benefit gas, and myogenic, the removing toxic substances of holder sore is for making medicine.All medicines share, and play the effect of clearing heat-fire, removing toxic substances, antibacterial, anti-inflammatory altogether.
This Chinese herb feed additive, according to the dialectical theory of Chinese veterinarian, not only can prevent livestock and poultry and fur-bearing animal diarrhoea, and result for the treatment of is remarkable.As prevented the diseases such as animal diarrhea such as chicken, duck, goose, quail, ox, sheep, donkey, camel, fox, racoon dog, ermine, rabbit all to have good curative effect, total effective rate is more than 96%.When being used for the treatment of, total effective rate is more than 97%.
Chinese herbal feed additive of the present invention, regulates using dosage can prevent or treat the diarrhoea of livestock and poultry and fur-bearing animal significantly, and during as prevention, general addition is the 0.4-0.6% of feeding quality; If treatment diarrhoea, using dosage is 0.5-1.5%.During use, after said medicine can being pulverized, cross 300 mesh sieves, what obtain is powder.Select according to actual conditions during use, as scale livestock farming can adopt spice mixed feeding method, raising family scattered both can spice mixed feeding, also powder decocting can be got juice drinking-water, also can gavage.
Chinese herb feed additive of the present invention is pure tcm product, can effectively avoid anti-milk, medicament residue and food-safety problem, various formulation (as powder, oral liquid, granule, tablet, pill, paste etc.) can be processed into simultaneously and be suitable for promoting in husbandry sector.
Detailed description of the invention
With specific embodiment, technical scheme of the present invention is described below, but protection scope of the present invention is not limited thereto:
Embodiment 1
The additive of control livestock and poultry and fleece animal diarrhoea, composed as follows:
Coptis 15g, golden cypress 20g, moutan bark 15g, radix paeoniae rubrathe 17.5g, mother chrysanthemum 15g, Radix Astragali 12.5g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 2
The additive of control livestock and poultry and fleece animal diarrhoea, composed as follows:
Coptis 10g, golden cypress 15g, moutan bark 10g, radix paeoniae rubrathe 15g, mother chrysanthemum 10g, Radix Astragali 10g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 3
The additive of control livestock and poultry and fleece animal diarrhoea, composed as follows:
Coptis 20g, golden cypress 25g, moutan bark 20g, radix paeoniae rubrathe 20g, mother chrysanthemum 20g, Radix Astragali 15g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 4
The additive of control livestock and poultry and fleece animal diarrhoea, composed as follows:
Coptis 15g, golden cypress 20g, moutan bark 15g, radix paeoniae rubrathe 17.5g, mother chrysanthemum 15g, Radix Astragali 12.5g, root of large-flowered skullcap 12.5g, selfheal 17.5g, thick wood-fern rhizome 12.5g, lophatherum gracile 12.5g, cordate houttuynia 15g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 5
The additive of control livestock and poultry and fleece animal diarrhoea, composed as follows:
Coptis 10g, golden cypress 15g, moutan bark 10g, radix paeoniae rubrathe 15g, mother chrysanthemum 10g, Radix Astragali 10g, root of large-flowered skullcap 10g, selfheal 15g, thick wood-fern rhizome 10g, lophatherum gracile 10g, cordate houttuynia 10g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Embodiment 6
The additive of control livestock and poultry and fleece animal diarrhoea, composed as follows:
Coptis 20g, golden cypress 25g, moutan bark 20g, radix paeoniae rubrathe 20g, mother chrysanthemum 20g, Radix Astragali 15g, root of large-flowered skullcap 15g, selfheal 20g, thick wood-fern rhizome 15g, lophatherum gracile 15g, cordate houttuynia 20g.
All medicine pulverizations cross 300 mesh sieves, obtain powder.
Effect:
Embodiment 1 additive spice is taken orally: when being used for the treatment of, the large domestic animal such as ox, horse and camel: 150-300g/ head; Pig, sheep: 50-100g/ head, only, only, bird: 1-3g/ only, adds up curative effect after being used in conjunction 5 days to rabbit: 6-12g/ to fox, racoon dog, ermine: 15-30g/.Preventive dose reduces by half.
Efficacy determination: during prevention, protective rate is considered as effectively more than 96%.During treatment, take medicine 5, symptom of diarrhea is eliminated, and in 7 days not repeatedly, is considered as curing; In 10 days, without symptom of diarrhea, be considered as effectively, otherwise invalid.Effect refers to table 1(prevention) and table 2(treatment).
Table 1
Table 2
Embodiment 4 additive spice is taken orally: during treatment, the large domestic animal such as ox, horse and camel: 150-300g/ head; Pig, sheep: 50-100g/ head, only, only, bird: 1-3g/ only, or according to forage volume 0.5-1.5% spice mixed feeding, adds up curative effect after being used in conjunction 5 days to rabbit: 6-12g/ to fox, racoon dog, ermine: 15-30g/.Preventive dose reduces by half.
Efficacy determination is with embodiment 1 additive.The results detailed in Table 3(prevention) and table 4(treatment).
Table 3
Table 4
Concrete case 1
In June, 2010,20000 quails that Xuchang Changge City Liu raises, randomly draw 900, are divided into test group and control group, each 450.Two groups of conveniently raising, immunity inoculation, sterilizations etc. in unified house.
The Chinese medicine composition of Example 1 is pulverized, and crosses 300 mesh sieves, and test group adds feed according to 0.5% ratio and after mixing, free choice feeding, the interpolation time from 28 ages in days until 35 ages in days.Period, control group occurred that the quail of diarrhoea death amounts to 43, the death rate 9.56% except natural death; Test group because of dead quail 11 of suffering from diarrhoea, the death rate 2.44%.
Concrete case 2
In January, 2010,12000 817 broiler chicken that Mengzhou City Lee raises, randomly draw 600 and be divided into test group and control group, except conveniently raising, immunity inoculation, sterilization etc., the Chinese medicine composition of Example 1 is pulverized, cross 300 mesh sieves, test group is added feed according to 0.6% ratio and is made particle after mixing.According to Lee plant incidence in the past, diarrhoea is many to start about 30 ages in days, therefore tests and be added into 31 ages in days from 26 ages in days.Period, control group occurred that the chicken of diarrhoea death amounts to 28, the death rate 9.33% except natural death; Test group because of dead chicken 5 of suffering from diarrhoea, the death rate 1.67%.Continue test group in observation 10 days and have no symptom of diarrhea, there is symptom of diarrhea in control group, because of dead chicken 8 of suffering from diarrhoea.
Concrete case 3
In February, 2011, the pig farm of Xiping County Lee extracts 8 nests out at random with the piglet 92 of age in days with pig house, test group 45, control group 47, duration of test test group and control group are except conveniently yard feeding pattern raising, immunity inoculation, sterilization etc., and the Chinese medicine composition of Example 2 is pulverized, and crosses 300 mesh sieves, test group, according to 30g/ head, makes an addition to feed and makes particle after mixing.Wean first 4 days, bring into use, be used in conjunction 5 days.Not there is symptom of diarrhea, efficient 100.0% in period test group 45 piglets; 5 are had to occur diarrhoea, the incidence of disease 10.64% in control group 47 piglets.According to 50g/ head after morbidity, decocting is got juice and is gavaged, and once a day, is used in conjunction 5, and wherein 2 serious sick pigs adopt andrographis paniculata injection and injection liquid of gentamicin to carry out treatment 3 days, fully recover after 5 days.Test group and control group continue observation 10 days after off-test, have no symptom of diarrhea.
Concrete case 4
In November, 2009,15000 laying hens that Liangyuan District, Shangqiu Lee raises, randomly draw 1000 and are divided into test group and control group, except conveniently raising, immunity inoculation, sterilization etc., the Chinese medicine composition of Example 4 is pulverized, cross 300 mesh sieves, test group adds feed according to 0.6% ratio, mixes rear for chicken free choice feeding, to suffer from diarrhoea occurrence regularity according to this laying hen in the past, generally suffer from diarrhoea during 100 age in days to 125 ages in days, therefore test group is added from 95 ages in days, is used in conjunction 10 days.Control efficacy observation: duration of test, control group chicken group the dead chicken 64 of 95 to 145 age in days internal causes diarrhoea, the death rate 12.8%; Test group is none death in 95 to 145 ages in days.
Concrete case 5
In April, 2012,7500 large-scale white meat-type chickens of block that Huojia County Wang raises, in 27 age in days skies, occur that ight soil is thin in water sample, occasionally have yellow, white, green ight soil, there is undergrowth in serious broiler chicken, body is become thin, hat whisker turns white, and falls ill after 3 days, and chicken starts to occur death; Chicken intestinal mucosa of dying of illness is congested, hemorrhage, come off, and intestines wall is thinning, and cloaca is hemorrhage, interior just like watery yellow-white ight soil etc.The Chinese medicine composition of Example 5 is pulverized, is crossed 300 mesh sieves and mix; This powder is got to boil water by 0.75% of material feeding amount, liquid medicine is drunk water, dregs of a decoction spice, after being used in conjunction 5 days, symptom disappears substantially, does not occur Relapse rate in 7 days, and disease must heal, dead chicken 294 is total to during medication,, there is not symptom of diarrhea and death on the 5th, 6,7 day in the death rate 3.92%, does not find symptom of diarrhea and none example death in the 8th, 9,10 day.
Concrete case 6
In December, 2010,220, Runan County piglet is suffered from diarrhoea suddenly, discharges milky or linen pulpous state, pasty state stickiness ight soil, then sick pig occurs that spirit is tired, and by hair slightly disorderly, body surface is unglazed, anorexia, weakness of limbs, walking is unstable or sleeping ground is difficult rises, ight soil is canescence stench, slack anus, fecal incontinence, becomes thin, dewaters, indivedual pig extremely feeble and dead, the death rate 5.45%.Pathological change is that sick dead pig corpse is become thin, and mucous membrane is pale, anus and around faecal contamination, and intestinal mucosa is catarrhal inflammation, and intestines wall is thinning, has milky or canescence pasty state or ointment shape content, lymphonodi mesenterici mild swelling etc. in colon.Through clinical symptoms, pathological change and laboratory diagnosis, be diagnosed as the white scour of piglet.
The Chinese medicine composition of Example 6 is pulverized, cross 300 mesh sieves, test group is according to 50g/ head, and decocting is got juice and gavaged, once a day, serve on 5, the salt of fluid infusion simultaneously drinking-water is used in conjunction 3 days, and after 5 days, symptom disappears substantially, Relapse rate is not there is in 10 days, recovery from illness, except 1 piglet is because of except serious dehydration death during medication, more dead without piglet.
Concrete case 7
In January, 2011, there is poor appetite in piglet about Neihuang County Lee buys 120 60 ages in days from other places, and spirit is depressed, vomiting and mucus diarrhoea, and between ight soil or have blood or come to mucous membrane tissue fragment etc., case fatality rate is 8.3%.Pathological change is based on enteron aisle.Small intestinal mucosa and mesenterium are congested, hemorrhage, dilatation of intestine, in be full of yellow liquid, intestinal villi shortens, and severe one Villus atrophy, even disappears; Colorectal mucosa generation Catarrhal, hemorrhagic enteritis, colon and the swelling of caecum mucous membrane, gauffer is obvious, above with mucus, clot and fibrinous exudate etc.Swine dysentery and epidemic diarrhea mixed infection is diagnosed as through clinical symptoms, pathological change and laboratory diagnosis.
The Chinese medicine composition of Example 4 is pulverized, cross 300 mesh sieves, test group is according to 60g/ head, and decocting is got juice and gavaged, once a day, serve on 5, dregs of a decoction spice, the salt of fluid infusion simultaneously drinking-water is used in conjunction 3 days, and piglet serious individually coordinates andrographis paniculata injection, mequindox injection and interferon intramuscular injection, every day 1 time, be used in conjunction 3 days.After 5 days, symptom of diarrhea disappears substantially, does not occur Relapse rate in 7 days, recovery from illness, and during medication, none piglet is dead.
Concrete case 8
In May, 2012,96 weanling pigs that Yingyang Cui raises cause diarrhoea because of pellet of searching for food, and the Chinese medicine composition of Example 1 is pulverized, mistake 300 mesh sieves, test group is according to 50g/ head, decocting is got juice and is gavaged, and 1 time on the one, serve on 3, after 3 days, symptom of diarrhea disappears substantially, do not occur symptom of diarrhea in 10 days, pig grows fine, and each side is normal.
Above-described embodiment is the preferred embodiment of the present invention, but embodiments of the present invention are not restricted to the described embodiments, and the change that other any the present invention of not deviating from does all should be equivalent substitute mode, is included within protection scope of the present invention.
Claims (1)
1. prevent and treat the Chinese herbal feed additive of livestock and poultry and fur-bearing animal diarrhoea, it is characterized in that, be made up of following weight portion Chinese herbal medicine: coptis 10-20 part, golden cypress 15-25 part, moutan bark 10-20 part, radix paeoniae rubrathe 15-20 part, mother chrysanthemum 10-20 part, Radix Astragali 10-15 part, root of large-flowered skullcap 10-15 part, selfheal 15-20 part, thick wood-fern rhizome 10-15 part, lophatherum gracile 10-15 part, cordate houttuynia 10-20 part.
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| CN105879003A (en) * | 2014-11-24 | 2016-08-24 | 李雷 | Traditional Chinese medicinal composition for treating lamb diarrhea |
| CN104840934A (en) * | 2015-06-11 | 2015-08-19 | 鲁东大学 | Traditional Chinese medicine composition for preventing and treating piglet diarrhea and preparation method of traditional Chinese medicine composition |
| CN104970198A (en) * | 2015-06-29 | 2015-10-14 | 何以安 | Feed additive for preventing and treating diarrhoea of cows |
| CN105010826A (en) * | 2015-06-29 | 2015-11-04 | 何以安 | Lamb diarrhea preventing and curing feed additive |
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| CN101926411A (en) * | 2010-09-14 | 2010-12-29 | 丽水市林业科学研究院 | Heartleaf houttuynia herb livestock and poultry feed additive and preparation method thereof |
| CN102038082A (en) * | 2010-09-02 | 2011-05-04 | 吴艳霞 | Traditional Chinese medicinal feed additive for treating dysentery and diarrhea of livestock and poultry |
| CN102232467A (en) * | 2011-04-15 | 2011-11-09 | 北京康华远景科技有限公司 | Livestock and poultry anti-diarrheal feed additive and preparation method thereof |
| CN102379962A (en) * | 2010-09-03 | 2012-03-21 | 山东绿源新食品有限公司 | Traditional Chinese medicine combination for healthcare and treatment of livestock |
| CN102429967A (en) * | 2011-12-29 | 2012-05-02 | 甘肃农业大学 | Traditional Chinese medicine composition for preventing and treating bacterial diarrhea of livestock and poultry and application thereof |
| CN102640864A (en) * | 2012-02-23 | 2012-08-22 | 上海交通大学 | Chinese medicinal herb feed additive for improving immunity of chickens and preventing diarrhea and using method for additive |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102038082A (en) * | 2010-09-02 | 2011-05-04 | 吴艳霞 | Traditional Chinese medicinal feed additive for treating dysentery and diarrhea of livestock and poultry |
| CN102379962A (en) * | 2010-09-03 | 2012-03-21 | 山东绿源新食品有限公司 | Traditional Chinese medicine combination for healthcare and treatment of livestock |
| CN101926411A (en) * | 2010-09-14 | 2010-12-29 | 丽水市林业科学研究院 | Heartleaf houttuynia herb livestock and poultry feed additive and preparation method thereof |
| CN102232467A (en) * | 2011-04-15 | 2011-11-09 | 北京康华远景科技有限公司 | Livestock and poultry anti-diarrheal feed additive and preparation method thereof |
| CN102429967A (en) * | 2011-12-29 | 2012-05-02 | 甘肃农业大学 | Traditional Chinese medicine composition for preventing and treating bacterial diarrhea of livestock and poultry and application thereof |
| CN102640864A (en) * | 2012-02-23 | 2012-08-22 | 上海交通大学 | Chinese medicinal herb feed additive for improving immunity of chickens and preventing diarrhea and using method for additive |
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