CN103041005A - Traditional Chinese medicine composition with effect of astringing intestine to stop diarrhea, and preparation method thereof - Google Patents
Traditional Chinese medicine composition with effect of astringing intestine to stop diarrhea, and preparation method thereof Download PDFInfo
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- CN103041005A CN103041005A CN2011103114142A CN201110311414A CN103041005A CN 103041005 A CN103041005 A CN 103041005A CN 2011103114142 A CN2011103114142 A CN 2011103114142A CN 201110311414 A CN201110311414 A CN 201110311414A CN 103041005 A CN103041005 A CN 103041005A
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Abstract
The invention relates to a traditional Chinese medicine composition with an effect of astringing intestine to stop diarrhea, and the traditional Chinese medicine composition comprises the following components in parts by weight: 3-14 parts of the root of Chinese pulsatilla, 1-10 parts of rhizoma coptidis, 2-12 parts of cortex phellodendri, 4-17 parts of purslane, 1-10 parts of fructus mume, 1-10 parts of medicine terminalia fruit, 2-12 parts of radix aucklandiae, 8-20 parts of rhizoma atractylodis, 1-10 parts of radix sophorae flavescentis, 1-10 parts of liquorice, 1-10 parts of dandelion and 1-10 parts of talcum. The traditional Chinese medicine composition is scientific and reasonable in formulation composition, has the functions of clearing away heat and toxic materials, astringing intestine to stop diarrhea, improving the immunity, resisting virus and refreshing and restoring consciousness, is free from toxic and side effects as well as drug residue, and is convenient to use, lower in cost, high in killing rate of bacteria and virus pathogenic microorganism and free from drug resistance.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition with intestine-astringing and dysentery-relieving function and preparation method thereof.
Background technology
The white scour of chicken is a kind of common transmittable disease that is caused by the Pullorum Disease Salmonella, the main harm chickling, and incidence and mortality is high.Young group is crowded, room temperature crosses that to exceed low, feedstuff shortage, improper ventilation, high humidity, poor hygienic be the principal element of bringing out primary disease, and the feces of sick chicken is the main source of infection.Adult Chicken is chronic or recessive process more, often contains the Pullorum Disease Salmonella in the ovary of Adult Chicken, intestinal, testis, the seminal fluid, and cock is passed to bacterium hen and pollutes fertile egg by copulation, and hen is passed to chickling by hatching egg.The chicken output egg that carries disease germs owing to carry disease germs, the egg that carries disease germs are hatched dead young bird or sick young, infect other chickling, and the chicken of sick young bird and anti-mistake can carry disease germs for a long time, thereby primary disease is handed down from age to age at Ji Qunzhong, move in circles, and harm seriously.
Chicken of salmonellal various age of Pullorum Disease generable a kind of infectious disease all, chickling morbidity performance acute sepsis process is take heating, draw canescence medicated porridge sample or the aqueous feces of viscosity as feature; It is that main chronic or inapparent infection is feature that Adult Chicken falls ill to damage reproductive system.This bacterium of cause of disease is the slightly elongated bacillus of circle of two ends, and Gram-negative can not be moved, and without pod membrane, does not form spore, is facultative anaerobe.The pathogen of primary disease is the Pullorum Disease Salmonella, is a member of enterobacteriaceae, Gram-negative.In the internal organs of sick chicken pathogenic bacteria is arranged, with maximum in liver, lung, yolk sac, testis and the painstaking effort.Under field conditions (factors), the resistance of pathogenic bacteria is stronger, pathogenic bacteria on the dried cloth, can survive at ambient temperature 7 years 8 months again, in soil, can survive 14 months, pathogenic bacteria in the hen house can survive to Second Year, can survive on roost 10～105 days, and temperature is-3 ℃～8 ℃, can survives when humidity is 65%～75% 62 days on wooden feed trough.This bacterium is not strong to the resistance of heat, and the egg of pollution boils and can kill this bacterium in 5 minutes, and 70 ℃ through also making it dead in 20 minutes, and general disinfectant can both kill rapidly.
Along with the development of China's animal husbandry, the gal virus infectious disease continues to increase, and traditional Chinese herbal medicine or decoction and existing just work at analgesic, dysentery relieving, antibiosis with Western medicine, and can not fundamentally remove viral puzzlement to body.Long-term abuse of antibiotics, sulfonamides and some chemical drugss, make virus, antibacterial produce drug resistance, using dosage increases greatly and curative effect descends to some extent, continues to increase aquaculture cost, has also increased the harm of the residual and toxic and side effects of medicine in the poultry body to human body.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition with intestine-astringing and dysentery-relieving function, this Chinese medicine composition heat-clearing and toxic substances removing, relieving dysentery with astringents, lifting immunity, antiviral, pure and fresh refreshment, have no side effect, and drug residue can not occur, easy to use, cost is lower, and is high and have no drug resistance to the killing rate of antibacterial, virus causing disease microorganism.
Another object of the present invention is to provide a kind of preparation method with Chinese medicine composition of intestine-astringing and dysentery-relieving function.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition with intestine-astringing and dysentery-relieving function, the component of its Chinese medicine composition and ratio of weight and number thereof are:
Radix Pulsatillae 3-14 part; Rhizoma Coptidis 1-10 part;
Cortex Phellodendri 2-12 part; Herba Portulacae 4-17 part;
Fructus Mume 1-10 part; Fructus Chebulae 1-10 part;
Radix Aucklandiae 2-12 part; Rhizoma Atractylodis 8-20 part;
Radix Sophorae Flavescentis 1-10 part; Radix Glycyrrhizae 1-10 part;
Herba Taraxaci 1-10 part; Talcum 1-10 part.
And this Chinese medicine composition component and optimum ratio of weight and number thereof are respectively:
6 parts of the Radix Pulsatillaes; 3 parts of Rhizoma Coptidis;
4 parts of Cortex Phellodendris; 6 parts of Herba Portulacaes;
3 parts of Fructus Mumes; 2 parts of Fructus Chebulaes;
4 parts of the Radix Aucklandiae; 12 parts of Rhizoma Atractylodis;
2 parts of Radix Sophorae Flavescentiss; 2 parts in Radix Glycyrrhizae;
2 parts of Herba Taraxacis; 2 parts in Talcum.
A kind of preparation method with Chinese medicine composition of intestine-astringing and dysentery-relieving function, the step of its preparation method is:
(1). take by weighing respectively the Radix Pulsatillae, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Fructus Mume, Fructus Chebulae, the Radix Aucklandiae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Radix Glycyrrhizae, Herba Taraxaci, Talcum pulverizing afterwards all by the 80-100 mesh sieve according to weight proportion;
(2). the Radix Pulsatillae after will sieving, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Fructus Mume, Fructus Chebulae, the Radix Aucklandiae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Radix Glycyrrhizae, Herba Taraxaci, Talcum mix homogeneously namely obtain the Chinese medicine composition that finished product has intestine-astringing and dysentery-relieving function.
Advantage of the present invention and beneficial effect are:
1. the Rhizoma Coptidis, Cortex Phellodendri, the Radix Pulsatillae, Talcum, the Cortex Phellodendri that originally have the Chinese medicine composition of intestine-astringing and dysentery-relieving function have good heat-clearing and toxic substances removing, relieving dysentery with astringents effect.Radix Glycyrrhizae, the Radix Aucklandiae, Herba Taraxaci, Herba Portulacae have good lifting immunity, especially bacterial disease etc. are had good prevention and therapeutic effect, especially toxin expelling, hepatic cholagogic, pure and fresh refreshment and the raising immunity of organisms of body are had good effect, popularity digestive system infectious disease cure rate is higher.
2. the Chinese medicine composition broad-spectrum high efficacy that originally has intestine-astringing and dysentery-relieving function, to the gastric acid quite stable, the rear absorption well for oral administration do not affected by water temperature, acid-base value, just can reach the blood peak concentration of drug at extremely low concentration and in the short period simultaneously.
3. the present invention fills a prescription and forms scientific and reasonablely, and heat-clearing and toxic substances removing, relieving dysentery with astringents, lifting immunity, antiviral, pure and fresh refreshment have no side effect, and drug residue can not occur, easy to use, cost is lower, and is high and have no drug resistance to the killing rate of antibacterial, virus causing disease microorganism.
The specific embodiment
The present invention is described in further detail by following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
The Radix Pulsatillae in the component of the present invention, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Fructus Mume, Fructus Chebulae, the Radix Aucklandiae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Radix Glycyrrhizae, Herba Taraxaci, Talcum all can be bought in market and obtain.
Embodiment 1
A kind of Chinese medicine composition with intestine-astringing and dysentery-relieving function, component and the weight thereof of its Chinese medicine composition are respectively: Radix Pulsatillae 3kg, Rhizoma Coptidis 1.5kg, Cortex Phellodendri 2kg, Herba Portulacae 3kg, Fructus Mume 1.5kg, Fructus Chebulae 1kg, Radix Aucklandiae 2kg, Rhizoma Atractylodis 6kg, Radix Sophorae Flavescentis 1kg, Radix Glycyrrhizae 1kg, Herba Taraxaci 1kg, Talcum 1kg.
A kind of preparation method with Chinese medicine composition of intestine-astringing and dysentery-relieving function, the step of its preparation method is:
(1). take by weighing respectively the Radix Pulsatillae, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Fructus Mume, Fructus Chebulae, the Radix Aucklandiae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Radix Glycyrrhizae, Herba Taraxaci, Talcum pulverizing afterwards all by the 80-100 mesh sieve according to weight proportion;
(2). the Radix Pulsatillae after will sieving, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Fructus Mume, Fructus Chebulae, the Radix Aucklandiae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Radix Glycyrrhizae, Herba Taraxaci, Talcum mix homogeneously namely obtain the Chinese medicine composition that finished product has intestine-astringing and dysentery-relieving function.
Embodiment 2
A kind of Chinese medicine composition with intestine-astringing and dysentery-relieving function, component and the weight thereof of its Chinese medicine composition are respectively: Radix Pulsatillae 14kg, Rhizoma Coptidis 10kg, Cortex Phellodendri 2kg, Herba Portulacae 4kg, Fructus Mume 10kg, Fructus Chebulae 10kg, Radix Aucklandiae 2kg, Rhizoma Atractylodis 8kg, Radix Sophorae Flavescentis 1kg, Radix Glycyrrhizae 1kg, Herba Taraxaci 10kg, Talcum 10kg.
The step of its preparation method is with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition with intestine-astringing and dysentery-relieving function, component and the weight thereof of its Chinese medicine composition are respectively: Radix Pulsatillae 3kg, Rhizoma Coptidis 1kg, Cortex Phellodendri 12kg, Herba Portulacae 17kg, Fructus Mume 1kg, Fructus Chebulae 1kg, Radix Aucklandiae 12kg, Rhizoma Atractylodis 20kg, Radix Sophorae Flavescentis 10kg, Radix Glycyrrhizae 10kg, Herba Taraxaci 1kg, Talcum 1kg.
The step of its preparation method is with embodiment 1.
Embodiment 4
A kind of Chinese medicine composition with intestine-astringing and dysentery-relieving function, component and the weight thereof of its Chinese medicine composition are respectively: Radix Pulsatillae 3kg, Rhizoma Coptidis 1.5kg, Cortex Phellodendri 2kg, Herba Portulacae 3kg, Fructus Mume 1.5kg, Fructus Chebulae 1kg, Radix Aucklandiae 2kg, Rhizoma Atractylodis 6kg, Radix Sophorae Flavescentis 1kg, Radix Glycyrrhizae 1kg, Herba Taraxaci 1kg, Talcum 1.5kg.
The step of its preparation method is with embodiment 1.
Using method of the present invention is by the administration of each chickling 0.5g/ plumage.Spice of the present invention or drinking-water, with the present invention to poultry feed can reach the treatment disease effect.
Clinical trial
Use advantage of the present invention below by concrete description of test:
1. the present invention is to the therapeutic test of animality experimental chicken digestive tract Salmonella infection:
1.1.5 100 of age in days Ai Weiyin chickling, random packet, 25 every group, totally four groups.Be prevention group of the present invention, treatment group of the present invention, young dysentery spirit matched group, blank group.
1.2. strain is bought by China Veterinery Drug Inspection Office, inoculates in proportion, dilution, packing, sealing, preservation.
1.3. prevention group of the present invention is by the administration of every 8g/kg mixed feeding, be used in conjunction two days later drug withdrawal, all press 0.8mg/ oral administration to other three groups, inoculate and treat after 2 hours, dosage is that of the present invention group and matched group are all by the administration of 30g/kg mixed feeding, be used in conjunction drug withdrawal in three days and observe two days later, not administration of matched group was observed four to five days, the survival chicken is slaughtered checked mycoplasma number in the body.Result such as following table:
| The example number | Prevention group of the present invention | Treatment group of the present invention | Young dysentery spirit treatment group | The blank group |
| Inoculation number (only) | 25 | 25 | 25 | 25 |
| Cure number (only) | 20 | 24 | 14 | 1 |
| Death toll (only) | 5 | 1 | 11 | 24 |
| Survival rate (%) | 80 | 96 | 66 | 4 |
As seen from the above table prevention group of the present invention medication drug withdrawal after three days has 5 to occur deadly behind the counteracting toxic substances, survive 20, prevents protective rate 80%, and dead 24 of blank group only has 4% survival rate, and two groups relatively differ highly significant.The preventive effect ideal very that the present invention infects Salmonella gallinarum is described; Dead 1 for the treatment of group of the present invention, survival rate 96%, the cure rate of young dysentery spirit is 60%, illustrates that treatment of the present invention is loose apparently higher than young dysentery spirit.
2. to the treatment of the white scour of chicken
Heishan, Liaoning plant 817 little assorted chickens, 15 ages in days, 12000, minute two hen houses of A, B, A the full group of hen house sickness rate reaches more than 85%, and B the full group of hen house sickness rate reaches 90% or more individually that death has appearred in chickens.Its jumpbogroup characteristics are: sick chicken spirit is depressed, the necking down of bowing, and the lethargy of closing one's eyes, the feather pine is random, and appetite descends or does not eat, and is afraid of cold and likes flocking together, and crop expands and is full of liquid.Outstanding performance is dysentery, discharges a kind of loose stool of white limy pulpous state, and adheres on the perianal feather.Defecation frequency is many, makes anus often by sticky sealing, affects defecation, feels pain during sick young defecation and shriek occurs.The sick young dyspnea that has is stretched neck and is dehisced.The visible arthroncus that has, walking disorder is walked lamely the appearance blind that has.Cut open inspection: the chickling of acute death is without obvious pathological changes.Chronic process person's absorption of yolk at its is bad, is grease-like, and the heart, lung, liver, caecum and muscular stomach have necrosis region or tuberosity, and ureter significantly expands because of urate deposition, and cheesy embolus is arranged in the caecum.Blood is arranged sometimes, peritonitis is often arranged.Slightly large is sick young, and lung has the canescence tuberosity.The remarkable pathological changes of Adult Chicken is hepatomegaly, can reach normal 2～3 times, and kermesinus is to darkviolet, the slightly khaki that has, and the large necrosis region of the yellow-white grain of rice that as seen surface is dispersed in, quality is extremely crisp, easily breaks, and causes hemoperitoneum.Therapeutic Method is: pure Chinese medicine powder powder composite is pressed the consumption administration of per kilogram feedstuff 50g, and the 3rd day of medication begins to observe the jumpbogroup situation:
| The example number | A hen house | B hen house |
| Treatment number (only) | 8000 | 4000 |
| Cure number (only) | 7840 | 3920 |
| Death toll (only) | 160 | 80 |
| Cure rate (%) | 98.00 | 98.00 |
Can be learnt that by upper table up to more than 98.0%, other chickens are also got better and turn to the healing of the white scour of chicken.
3. the present invention has good lifting immunity to the chicken group
| The example number | Use of the present invention group | Do not use of the present invention group |
| Prevention number (only) | 2000 | 2000 |
| Morbidity number (only) | 167 | 531 |
| Death toll (only) | 6 | 197 |
| Prevention rate (%) | 96.41 | 62.90 |
Can be learnt by upper table, use and do not use the present invention to differ more than 30 points as the mortality rate of prophylactic chicken.
Can find out that by above-mentioned three experiments the treatment that occurs Hakuri after the present invention is to the Chickens Infected Salmonella and prevention all play good effect, be better than traditional prescription.Chinese patent medicine is better than traditional Western medicine with it aspect the drug residue free after use.
Claims (3)
1. Chinese medicine composition with intestine-astringing and dysentery-relieving function, it is characterized in that: the component of this Chinese medicine composition and ratio of weight and number thereof are:
Radix Pulsatillae 3-14 part; Rhizoma Coptidis 1-10 part;
Cortex Phellodendri 2-12 part; Herba Portulacae 4-17 part;
Fructus Mume 1-10 part; Fructus Chebulae 1-10 part;
Radix Aucklandiae 2-12 part; Rhizoma Atractylodis 8-20 part;
Radix Sophorae Flavescentis 1-10 part; Radix Glycyrrhizae 1-10 part;
Herba Taraxaci 1-10 part; Talcum 1-10 part.
2. the Chinese medicine composition with intestine-astringing and dysentery-relieving function according to claim 1, it is characterized in that: this Chinese medicine composition component and optimum ratio of weight and number thereof are respectively:
6 parts of the Radix Pulsatillaes; 3 parts of Rhizoma Coptidis;
4 parts of Cortex Phellodendris; 6 parts of Herba Portulacaes;
3 parts of Fructus Mumes; 2 parts of Fructus Chebulaes;
4 parts of the Radix Aucklandiae; 12 parts of Rhizoma Atractylodis;
2 parts of Radix Sophorae Flavescentiss; 2 parts in Radix Glycyrrhizae;
2 parts of Herba Taraxacis; 2 parts in Talcum.
3. preparation method with Chinese medicine composition of intestine-astringing and dysentery-relieving function as claimed in claim 1, it is characterized in that: the step of this preparation method is:
(1) takes by weighing respectively the Radix Pulsatillae, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Fructus Mume, Fructus Chebulae, the Radix Aucklandiae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Radix Glycyrrhizae, Herba Taraxaci, Talcum pulverizing afterwards all by the 80-100 mesh sieve according to weight proportion;
(2) Radix Pulsatillae, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Fructus Mume, Fructus Chebulae, the Radix Aucklandiae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Radix Glycyrrhizae, Herba Taraxaci, the Talcum mix homogeneously after will sieving namely obtains the Chinese medicine composition that finished product has intestine-astringing and dysentery-relieving function.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103919882A (en) * | 2013-05-16 | 2014-07-16 | 黎秋萍 | Chinese herbal medicine and food for treating chronic diarrhea |
| CN103948876A (en) * | 2014-05-14 | 2014-07-30 | 深圳市红瑞生物科技有限公司 | Medicine for treating parvovirus and preparation method thereof |
| CN104547187A (en) * | 2014-12-29 | 2015-04-29 | 河南天纳图生物科技有限公司 | Compound fermented traditional Chinese medicine for preventing and treating chicken salmonellosis |
| CN112168888A (en) * | 2020-11-12 | 2021-01-05 | 邓云波 | Pure traditional Chinese medicine composition powder for treating bacterial and viral intestinal diseases of livestock and poultry |
| CN114949064A (en) * | 2020-12-16 | 2022-08-30 | 河南牧业经济学院 | Preparation method of traditional Chinese medicine microecological preparation for treating enteritis and diarrhea of laying hens |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101342299A (en) * | 2008-08-25 | 2009-01-14 | 河北农业大学 | Medicament for preventing and controlling white diarrhea disease |
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2011
- 2011-10-14 CN CN2011103114142A patent/CN103041005A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101342299A (en) * | 2008-08-25 | 2009-01-14 | 河北农业大学 | Medicament for preventing and controlling white diarrhea disease |
Non-Patent Citations (1)
| Title |
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| 刘敬新 等: "中药防治雏鸡痢疾", 《河北畜牧兽医》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103919882A (en) * | 2013-05-16 | 2014-07-16 | 黎秋萍 | Chinese herbal medicine and food for treating chronic diarrhea |
| CN103948876A (en) * | 2014-05-14 | 2014-07-30 | 深圳市红瑞生物科技有限公司 | Medicine for treating parvovirus and preparation method thereof |
| CN104547187A (en) * | 2014-12-29 | 2015-04-29 | 河南天纳图生物科技有限公司 | Compound fermented traditional Chinese medicine for preventing and treating chicken salmonellosis |
| CN112168888A (en) * | 2020-11-12 | 2021-01-05 | 邓云波 | Pure traditional Chinese medicine composition powder for treating bacterial and viral intestinal diseases of livestock and poultry |
| CN114949064A (en) * | 2020-12-16 | 2022-08-30 | 河南牧业经济学院 | Preparation method of traditional Chinese medicine microecological preparation for treating enteritis and diarrhea of laying hens |
| CN114949064B (en) * | 2020-12-16 | 2023-04-28 | 河南牧业经济学院 | Preparation method of traditional Chinese medicine microecological preparation for treating enteritis and diarrhea of laying hens |
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Application publication date: 20130417 |