CN102640864B - Chinese medicinal herb feed additive for improving immunity of chickens and preventing diarrhea and using method for additive - Google Patents

Chinese medicinal herb feed additive for improving immunity of chickens and preventing diarrhea and using method for additive Download PDF

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CN102640864B
CN102640864B CN 201210042616 CN201210042616A CN102640864B CN 102640864 B CN102640864 B CN 102640864B CN 201210042616 CN201210042616 CN 201210042616 CN 201210042616 A CN201210042616 A CN 201210042616A CN 102640864 B CN102640864 B CN 102640864B
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additive
chicken
chinese
feed additive
root
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朱建国
沈强
张艳玲
安渊
李本强
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SHANGHAI SITIAN POULTRY CULTIVATION PROFESSIONAL COOPERATIVES
Shanghai Jiaotong University
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Shanghai Jiaotong University
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Abstract

The invention relates to a Chinese medicinal herb feed additive for improving the immunity of chickens and preventing diarrhea. The additive is formed by using fleece flower root, epimedium, pilose asiabell root, bighead atractylodes rhizome, tuckahoe, coptis, phellodendron, scutellaria, platycladi seed, jujube seed, Chinese angelica, peony, costus root, dark medicated leaven, dark malt, dark hawthorn, keel, oyster, areca nut, cyrtomium rhizome and liquorice as raw materials through screening, drying, crushing, mixing and packing. The additive is used for feeding for two treatment courses in a certain ratio. The medicament consisting of natural Chinese medicinal herbs is used as the additive according to the compatible regulation of Chinese medicaments and modern pharmacological research by combining the physiological characteristics of the chickens and applied to raising of the chickens and replaces antibiotics, so the additive does not have any toxic or side effect and plays good roles in enhancing the physique, improving the immunity of the body, enhancing the pathogenic microorganism resistance of the body and reducing diseases. High economic benefits are obtained with low input, and an effective path is provided for reducing antibiotic residue in animal products.

Description

Improve Chinese herbal feed additive and the using method thereof of chicken immunity prevention diarrhoea
Technical field
The present invention relates to medical technical field, particularly a kind of Chinese herbal feed additive is used for strengthening the physique of chicken, improves immunity, the generation of prevention chicken diarrhea.
Background technology
Chicken group diarrhoea has multiple reason, and mainly contain: one by causing; The 2nd, caused by the feed source; The 3rd, caused by eqpidemic disease; The 4th, inappropriate medication.Wherein, eqpidemic disease is the factor that causes that chicken diarrhea is main.Bacterial diarrhea is multiple is born in young chicken, and the death rate is very high; Virus diarrhea is multiple is born in growing chickens and becomes chicken, suffers from chicken and persistence diarrhoea occurs; Parasitic diarrhea, parasite species difference symptom is different because causing a disease.In addition, the diarrhoea that causes because of inappropriate medication initiation suprainfection also is common.Beneficial bacterium in the normal chicken enteron aisle, when the chicken body suffers bacterium or virus infections, be killed simultaneously owing to use antibiotics, make the intestinal environment disequilibrium, enteron aisle is digested and assimilated and is obstructed, and high amount of drug is absorbed by the liver renal excretion by body simultaneously, causes the infringement of liver kidney function, final Abwehrkraft des Koepers descends, thereby causes suprainfection.Add that with high productivity individuality is little because chicken metabolism is vigorous, cause chicken lower to the disease tolerance, in case morbidity often has little time just death for the treatment of, the prevention of chicken disease seems and is even more important.
Because the present chicken of China is sick popular also very serious, chemicalses such as antibiotic remain be used to the first-selection of preventing and treating eqpidemic disease.This not only causes the appearance of a large amount of antibody-resistant bacterium, and cause chemicals residual in chicken, egg and products thereof, bring very big infringement for public health and food security, more do not meet the food consumption trend of people's " high-quality, low residual, green non-pollution of medicine ".This shows, seek a kind of not only safe and effective but also alternative antibiotic medicine seems particularly important.The immunity function of animal body is that body is resisted the important force that disease is recovered the body normal physiological function.Chinese herbal medicine because of its have aboundresources, effect extensively, treat both principal and secondary aspect of disease, safety and low toxicity, cheap, be difficult for producing extremely people's favor of advantage such as drug resistance, and modern pharmacological research has confirmed that many Chinese herbal medicines have the effect that improves immunity of organisms and anti-pathogenic microorganisms.The present invention as feed addictive, not only improves the generation of chicken immunity prevention diarrhoeal diseases with Chinese herbal medicine, has also avoided chemicalses such as antibiotic to use profitable strain in the chicken enteron aisle is destroyed and the suprainfection of generation.
Through the literature search to prior art, still a kind of relevant report of Chinese herbal feed additive that improves chicken immunity prevention diarrhoeal diseases of subject matter is therewith found at the end.
Summary of the invention
The objective of the invention is to provides a kind of Chinese herbal feed additive at the sick occurrence cause of chicken diarrhea and existing antibiotic therapy disadvantage, is used for strengthening the physique of chicken, improves immunity, the generation of prevention chicken diarrhea.Have that filling liver kidney replenishes qi to invigorate the spleen, the effect of analgesic malicious dampness removing and diarrhea-relieving, antitoxic heart-soothing and sedative, can improve chicken immunity, strengthen the resistance to microorganisms such as enteropathogenic Es.
For realizing this purpose, the Chinese herbal feed additive of raising chicken immunity prevention diarrhoeal diseases provided by the invention is made of following medicament: the fleece-flower root, barrenwort, Radix Codonopsis, the bighead atractylodes rhizome, Poria cocos, the coptis, golden cypress, the root of large-flowered skullcap, the seed of Oriental arborvitae, jujube kernel, Radix Angelicae Sinensis, Chinese herbaceous peony, the banksia rose, stir-baked MASSA FERMENTATA MEDICI-NALIS, melanoidin malt, charred FRUCTUS CRATAEGI, keel, oyster, betel nut, rhizome of cyrtomium, Radix Glycyrrhizae
The concrete component of Chinese herbal feed additive of the present invention is: be raw material with fleece-flower root 30-90G, barrenwort 15-45G, Radix Codonopsis 15-45G, bighead atractylodes rhizome 10-20G, Poria cocos 15-45G, coptis 5-15G, golden cypress 5-15G, root of large-flowered skullcap 5-15G, seed of Oriental arborvitae 10-20G, jujube kernel 10-20G, Radix Angelicae Sinensis 5-15G, Chinese herbaceous peony 5-15G, banksia rose 5-15G, stir-baked MASSA FERMENTATA MEDICI-NALIS 15-45G, melanoidin malt 15-45G, charred FRUCTUS CRATAEGI 15-45G, keel 30-90G, oyster 30-90G, betel nut 10-20G, rhizome of cyrtomium 10-20G, Radix Glycyrrhizae 6-18G, form through screening, drying and crushing, mixing packing.
The Chinese herbal feed additive of above-mentioned enhancing chicken physique prevention diarrhoeal diseases, the optimum weight proportioning of each raw material is: fleece-flower root 60G, barrenwort 30G, Radix Codonopsis 30G, bighead atractylodes rhizome 15G, Poria cocos 30G, coptis 10G, golden cypress 10G, root of large-flowered skullcap 10G, seed of Oriental arborvitae 15G, jujube kernel 15G, Radix Angelicae Sinensis 10G, Chinese herbaceous peony 10G, banksia rose 10G, stir-baked MASSA FERMENTATA MEDICI-NALIS 30G, melanoidin malt 30G, charred FRUCTUS CRATAEGI 30G, keel 60G, oyster 60G, betel nut 15G, rhizome of cyrtomium 15G, Radix Glycyrrhizae 10G
Take by weighing herbal raw material by above-mentioned consumption, after impurities in raw materials was removed in screening, drying and crushing was crossed 80 mesh sieves, mixes and makes powder, and medicament is made in packing again.
The said herbal medicine feed addictive cooperates and is used for strengthening chicken physique prevention diarrhoeal diseases, and concrete using method is: the medicament that above-mentioned Chinese medicine is formed can be used as chicken feed addictive, makes an addition in the feed by 1.5wt%, feeds continuously, and 1 month is a course for the treatment of.
The present invention mainly sets upright the theory of getting rid of evils according to the traditional Chinese medical science.Theory of traditional Chinese medical science thinks that positive unsaturated vapor is the internal cause that disease takes place, and perverse trend is the external cause that disease takes place.Add individual little reason owing to chicken metabolism is vigorous with high productivity, cause chicken lower to the disease tolerance, add flip-floies such as environment and diet, make chicken body transporting and transforming function of the spleen and stomach dull, then taste are weaker, cause damp and hot evil poison and take advantage of a weak point, and poor appetite occurs, rush down symptoms such as dysentery, dysphoria, in case it is just dead that morbidity often has little time treatment, the prevention of chicken disease seems and is even more important.At the cause of disease, drug prescription follows that filling liver kidney replenishes qi to invigorate the spleen, analgesic malicious dampness removing and diarrhea-relieving, antitoxic heart-soothing and sedative fundamentum, improves body physique, strengthens the resistance to microorganisms such as enteropathogenic Es.
Principle is as follows:
Fleece-flower root filling liver kidney benefiting essence-blood strengthening the bones and muscles in the medicament, barrenwort kidney-replenishing, modern pharmacological research are found the effect of its antibody horizontal that is significantly improved; The Radix Codonopsis tonifying middle-Jiao and Qi, promote the production of body fluid and nourish blood, the bighead atractylodes rhizome is invigorated the spleen and benefited qi, eliminating dampness Li Shui, the Poria cocos clearing damp and promoting diuresis, and invigorating the spleen, modern pharmacological research proves that the compound that these three kinds of Chinese medicines are formed can strengthen erythrocytic immunologic function, makes the immunologic cellular activity raising.Five medicines share to monarch drug in a prescription and play the effect that filling liver kidney replenishes qi to invigorate the spleen altogether.Be equipped with the coptis, golden cypress, root of large-flowered skullcap heat-clearing and damp-drying drug, purging intense heat and detonicating, modern pharmacological research proves that these three kinds of Chinese medicines have resisting pathogenic microbes, antitoxin, anti-inflammatory, analgesic, step-down, enhancing immunization.Three medicines share the effect of playing analgesic malicious dampness removing and diarrhea-relieving altogether.Be equipped with the seed of Oriental arborvitae, jujube kernel and play the effect of antitoxic heart-soothing and sedative altogether.Assistant is with Chinese angelica blood supplementing, promoting blood circulation and stopping pain, Chinese herbaceous peony nourish blood flat liver, astringing YIN to stop sweating, and blood-supplementing blood-nourishing is and oiliness, and to alleviate battalion's the moon of hindering because of diarrhoea, modern pharmacological research proof Radix Angelicae Sinensis can significantly improve erythrocytic immune adherence; In addition the hot temperature fragrance of the banksia rose is amusing, during promoting qi circulation and relieving pain is transferred, and burnt fortuneization during the assistant monarch drug in a prescription more can be urged, mechanism of qi perforation about making, diarrhoea can be ended; Assistant is played invigorating the spleen, food digesting action altogether with stir-baked MASSA FERMENTATA MEDICI-NALIS, melanoidin malt, charred FRUCTUS CRATAEGI, wherein stir-baked MASSA FERMENTATA MEDICI-NALIS, melanoidin malt its contain multiple digestive ferment, also contain saccharomycete, B family vitamin, improve a poor appetite, promote digestion; Assistant with keel, oyster tranquilizing mind, calming the liver, convergence is astringent or styptic treatment for spontaneous sweating, contains calcium carbonate, calcium phosphate, iron, potassium, sodium etc., the loss that can replenish body calcium; Assistant with the betel nut expelling parasite, help digestion, help clearing heat and detoxicating with rhizome of cyrtomium, end dysentery, desinsection, pharmacological research two medicines have the effect of resisting pathogenic microbes; Radix Glycyrrhizae coordinating the drug actions of a prescription, relieving spasm to stop pain, detoxifcation are for making medicine.
The present invention is based on the traditional Chinese medical science for the pathogenetic understanding of diarrhoeal diseases and principle of reatment, follow Chinese medicine matching principle and modern pharmacology to the research of Chinese medicine function, growth characteristic in conjunction with chicken, the medicament that natural Chinese medicinal herb is formed is as the feed addictive chicken of feeding, the physique that strengthens chicken is improved immunity of organisms, enhancing reduces the generation of diarrhoeal diseases and improves meat quality measuring good effect to the resistance of microorganisms such as enteropathogenic E.In its prescription the composition that contains of used Chinese herbal medicine have that filling liver kidney replenishes qi to invigorate the spleen, the effect of analgesic malicious dampness removing and diarrhea-relieving, antitoxic heart-soothing and sedative, to chicken because flip-floies such as environment and diet, immunity degradation, transporting and transforming function of the spleen and stomach is dull, causing damp and hot evil poison takes advantage of a weak point and causes the generation of diarrhoeal diseases, play and strengthen body physique, the effect of eliminating dampness detoxifcation antidiarrheal.Used Chinese herbal medicine is cheap common drug among the present invention, being made into chicken feed addictive takes, substitute antibiotic use, both without any side effects, can obviously improve chicken physique again, strengthen the evil sick ability of moisture-resistant, obtain high economic benefit with lower input, and for reduce in the animality goods antibiotic residue provide effectively by way of.
The specific embodiment
Below by specific embodiment technical scheme of the present invention is further described.Following examples do not constitute limitation of the invention.
Embodiment 1
Medicament is formed: fleece-flower root 60G, barrenwort 30G, Radix Codonopsis 30G, bighead atractylodes rhizome 15G, Poria cocos 30G, coptis 10G, golden cypress 10G, root of large-flowered skullcap 10G, seed of Oriental arborvitae 15G, jujube kernel 15G, Radix Angelicae Sinensis 10G, Chinese herbaceous peony 10G, banksia rose 10G, stir-baked MASSA FERMENTATA MEDICI-NALIS 30G, melanoidin malt 30G, charred FRUCTUS CRATAEGI 30G, keel 60G, oyster 60G, betel nut 15G, rhizome of cyrtomium 15G, Radix Glycyrrhizae 10G
Take by weighing herbal raw material by above-mentioned consumption, after impurities in raw materials was removed in screening, drying and crushing was crossed 80 mesh sieves, mixes and makes powder, and medicament is made in packing again.
The present invention selects 60 of the interior chickens of same hen house for use, be divided into 2 groups at random, the I group is control group, the basal diet of feeding, the II group is the Chinese herbal medicine group, presses 1.5wt% and add Chinese herbal feed additive in basal diet, and 1 month is a course for the treatment of, carry out feeding experiment totally two courses for the treatment of, gather chicken manure and just measure with the several common microbiological indicators of soil test.The present invention considers: enteron aisle pathogeny microorganism is the important cause of disease that causes chicken diarrhea, how to screen a kind of Chinese herbal feed additive and suppresses effective way that intestinal disease of chicken source microorganism then is prevention and treatment chicken diarrhea disease.And what of enteropahtogenic microganism directly are reflected in chicken manure just and by in the soil of fecal pollution.Therefore, the present invention selects Escherichia coli and the common pathogeny microorganism of two kinds of enteron aisles of salmonella as index, estimates Chinese herb feed additive and suppresses enteron aisle pathogeny action of microorganisms.
The explanation of example table: the present invention gathers the ight soil of a chicken weekly in two courses for the treatment of, carries out Escherichia coli and separates counting with salmonella, to measure Chinese herb feed additive to the restraint of intestinal disease of chicken source microorganism.
Table 1 different the medicine feed time chicken manure microorganism distribution situation
Figure BDA0000137772400000041
Can find out that from table 1 the colibacillary ight soil of experimental group carries disease germs quantity by week decline, to the beginning of the 3rd week and control group significant difference (P<0.01); Salmonella quantity also presents by descending in week in the experimental group ight soil, to the 3rd week and control group significant difference (P<0.01), illustrate that Chinese herbal feed additive has improved the immunity of body, levels such as body is antibiotic have been strengthened, thereby improved chicken undesirable element invasion and attack and the defensive ability/resistance ability that infects to external world, correspondingly reduced diarrhea disease percentage.
Consider that soil is the chicken survival environment, its situation of carrying disease germs directly has influence on the health of chicken.And the microorganism in the soil is to a great extent from ight soil, but also relevant with the behavior of herding and other environment.The present invention gathers soil weekly one time in two courses for the treatment of, carry out Escherichia coli and separate counting with salmonella, to measure Chinese herb feed additive to the influence power of pathogeny microorganism in the chicken living environment.
The mensuration that table 2 different time edaphon changes
Figure BDA0000137772400000051
Can find out that from table 2 the colibacillary soil of experimental group carries disease germs quantity by week decline, to the beginning of the 3rd week and control group significant difference (P<0.01); Salmonella quantity also presents by descending in week in the experimental group soil, to the 3rd week and control group significant difference (P<0.01), illustrate that Chinese herbal feed additive has reduced the microorganism in the soil indirectly, thereby improved chicken undesirable element invasion and attack and the defensive ability/resistance ability that infects to external world, correspondingly reduced diarrhea disease percentage.
Drawn by experimental result:
Chinese herbal feed additive provided by the invention can significantly improve the immunity function of chicken, with feed two the course for the treatment of best results.
The observed result of growing is as follows:
Experimental group is grown soon, and the feather light is moist, physically fit, and is active, do not have morbidity.By all being added the chicken tracing observation of medicine of the present invention, the result shows that this safety of medicine of use effectively has no adverse reaction.
Embodiment 2
Fleece-flower root 30G, barrenwort 15G, Radix Codonopsis 15G, bighead atractylodes rhizome 10G, Poria cocos 15G, coptis 5G, golden cypress 5G, root of large-flowered skullcap 5G, seed of Oriental arborvitae 10G, jujube kernel 10G, Radix Angelicae Sinensis 5G, Chinese herbaceous peony 5G, banksia rose 5G, stir-baked MASSA FERMENTATA MEDICI-NALIS 15G, melanoidin malt 15G, charred FRUCTUS CRATAEGI 15G, keel 30G, oyster 30G, betel nut 10G, rhizome of cyrtomium 10G, Radix Glycyrrhizae 6G
Embodiment 3
Fleece-flower root 90G, barrenwort 45G, Radix Codonopsis 45G, bighead atractylodes rhizome 20G, Poria cocos 45G, coptis 15G, golden cypress 15G, root of large-flowered skullcap 15G, seed of Oriental arborvitae 20G, jujube kernel 20G, Radix Angelicae Sinensis 15G, Chinese herbaceous peony 15G, banksia rose 15G, stir-baked MASSA FERMENTATA MEDICI-NALIS 45G, melanoidin malt 45G, charred FRUCTUS CRATAEGI 45G, keel 90G, oyster 90G, betel nut 20G, rhizome of cyrtomium 20G, Radix Glycyrrhizae 18G
The medicament preparation of above-described embodiment 2, embodiment 3 is with embodiment 1.
The use result who experiment showed, Chinese herbal feed additive of the present invention has following characteristics:
1, strengthens chicken physique and improve immunity;
2, prophylactic treatment diarrhoeal diseases;
3, strengthen the absorption of calcium iron, reduce the generation of dystrophic disease;
4, improve the quality of meat product.

Claims (2)

1. a Chinese herbal feed additive that improves chicken immunity prevention diarrhoeal diseases is characterized in that the weight of this Chinese herbal feed additive consists of: fleece-flower root 30-90g, barrenwort 15-45g, Radix Codonopsis 15-45g, bighead atractylodes rhizome 10-20g, Poria cocos 15-45g, coptis 5-15g, golden cypress 5-15g, root of large-flowered skullcap 5-15g, seed of Oriental arborvitae 10-20g, jujube kernel 10-20g, Radix Angelicae Sinensis 5-15g, Chinese herbaceous peony 5-15g, banksia rose 5-15g, stir-baked MASSA FERMENTATA MEDICI-NALIS 15-45g, melanoidin malt 15-45g, charred FRUCTUS CRATAEGI 15-45g, keel 30-90g, oyster 30-90g, betel nut 10-20g, rhizome of cyrtomium 10-20g and Radix Glycyrrhizae 6-18g.
2. the Chinese herbal feed additive of raising chicken immunity prevention diarrhoeal diseases according to claim 1 is characterized in that the weight of this Chinese herbal feed additive consists of: fleece-flower root 60g, barrenwort 30g, Radix Codonopsis 30g, bighead atractylodes rhizome 15g, Poria cocos 30g, coptis 10g, golden cypress 10g, root of large-flowered skullcap 10g, seed of Oriental arborvitae 15g, jujube kernel 15g, Radix Angelicae Sinensis 10g, Chinese herbaceous peony 10g, banksia rose 10g, stir-baked MASSA FERMENTATA MEDICI-NALIS 30g, melanoidin malt 30g, charred FRUCTUS CRATAEGI 30g, keel 60g, oyster 60g, betel nut 15g, rhizome of cyrtomium 15g and Radix Glycyrrhizae 10g.
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CN103798535A (en) * 2012-11-13 2014-05-21 天津瑞贝特科技发展有限公司 Feed additive capable of improving production performance of broiler chicken and preparation method of feed additive
CN103202900B (en) * 2013-04-01 2014-12-17 陈鹏举 Traditional Chinese medicine feed additive for preventing and curing livestock and poultry diarrhea
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CN104938801A (en) * 2014-03-25 2015-09-30 贵州柳江畜禽有限公司 Chicken feed for preventing and treating diarrhea
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CN108522880A (en) * 2018-03-14 2018-09-14 朱小涛 A kind of preparation method of feed for black bone chickens
CN109691595A (en) * 2019-01-21 2019-04-30 云南农业大学 A kind of Chinese herbal feed additive improving infection salmonella growth performance of chicks

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