CN102432496A - 一种卡比多巴的精制方法 - Google Patents
一种卡比多巴的精制方法 Download PDFInfo
- Publication number
- CN102432496A CN102432496A CN2011104398989A CN201110439898A CN102432496A CN 102432496 A CN102432496 A CN 102432496A CN 2011104398989 A CN2011104398989 A CN 2011104398989A CN 201110439898 A CN201110439898 A CN 201110439898A CN 102432496 A CN102432496 A CN 102432496A
- Authority
- CN
- China
- Prior art keywords
- carbidopa
- acid
- obtains
- bullion
- condition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201110439898 CN102432496B (zh) | 2011-12-23 | 2011-12-23 | 一种卡比多巴的精制方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201110439898 CN102432496B (zh) | 2011-12-23 | 2011-12-23 | 一种卡比多巴的精制方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102432496A true CN102432496A (zh) | 2012-05-02 |
CN102432496B CN102432496B (zh) | 2013-01-30 |
Family
ID=45980892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 201110439898 Active CN102432496B (zh) | 2011-12-23 | 2011-12-23 | 一种卡比多巴的精制方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102432496B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112574062A (zh) * | 2020-12-27 | 2021-03-30 | 浙江手心制药有限公司 | 卡比多巴对映异构体的分离制备方法 |
CN112939806A (zh) * | 2021-03-08 | 2021-06-11 | 山东新华制药股份有限公司 | 一种卡比多巴的精制方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3936495A (en) * | 1973-11-27 | 1976-02-03 | Merck & Co., Inc. | Purification process |
WO2007042848A2 (en) * | 2005-10-12 | 2007-04-19 | Egis Gyógyszergyár | Process for the preparation of carbidopa |
ES2333089A1 (es) * | 2009-07-24 | 2010-02-16 | Universitat Autonoma De Barcelona | Procedimiento e intermedios para la preparacion de l-carbidopa. |
-
2011
- 2011-12-23 CN CN 201110439898 patent/CN102432496B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3936495A (en) * | 1973-11-27 | 1976-02-03 | Merck & Co., Inc. | Purification process |
WO2007042848A2 (en) * | 2005-10-12 | 2007-04-19 | Egis Gyógyszergyár | Process for the preparation of carbidopa |
ES2333089A1 (es) * | 2009-07-24 | 2010-02-16 | Universitat Autonoma De Barcelona | Procedimiento e intermedios para la preparacion de l-carbidopa. |
Non-Patent Citations (5)
Title |
---|
《中国医药工业杂质》 20081231 钟为慧等 "卡比多巴的合成" 第730-732页 1-10 第39卷, 第10期 * |
《精细化工》 20070430 崔建国等 "从天然左旋多巴合成卡比多巴" 第387-391页 1-10 第24卷, 第4期 * |
SANDOR KARADY, ET AL.: ""Synthesis of D- and L-a-(3,4-Dihydroxybenzyl)-a-hydrazinopropionic Acid via Resolution"", 《J. ORG. CHEM.》 * |
崔建国等: ""从天然左旋多巴合成卡比多巴"", 《精细化工》 * |
钟为慧等: ""卡比多巴的合成"", 《中国医药工业杂质》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112574062A (zh) * | 2020-12-27 | 2021-03-30 | 浙江手心制药有限公司 | 卡比多巴对映异构体的分离制备方法 |
CN112939806A (zh) * | 2021-03-08 | 2021-06-11 | 山东新华制药股份有限公司 | 一种卡比多巴的精制方法 |
Also Published As
Publication number | Publication date |
---|---|
CN102432496B (zh) | 2013-01-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101245047A (zh) | 色氨酸提纯方法 | |
CN103087048B (zh) | 一种埃索美拉唑钠的纯化方法 | |
CN102942556A (zh) | 一种苯甲酸阿格列汀的制备工艺 | |
CN104402838B (zh) | 缬沙坦的精制方法 | |
CN103073438A (zh) | 一种盐酸氨溴索化合物的精制方法 | |
CN112645857A (zh) | 一种消旋羟蛋氨酸钙的制备方法 | |
CN102453011A (zh) | 一种高纯度柚皮素的制备方法 | |
CN102432496B (zh) | 一种卡比多巴的精制方法 | |
CN109485581B (zh) | 一种精制左旋多巴的方法 | |
CN103435567B (zh) | 缬沙坦的精制方法 | |
CN102180820B (zh) | 一种制备高纯度福多司坦的纯化方法 | |
CN102584693B (zh) | 一种高纯度2-氯-3-氨基吡啶盐酸盐的制备方法 | |
CN101781264B (zh) | 1-甲基-5-巯基-1,2,3,4-四氮唑的生产方法 | |
CN103113294B (zh) | 瑞巴派特的合成方法 | |
CN107488129B (zh) | 一种从l-缬氨酸复合物中提纯l-缬氨酸的方法 | |
CN103012509B (zh) | 一种分离提纯三氯蔗糖-6-乙酸酯母液的方法 | |
CN101781215A (zh) | 棓丙酯原料药化学半合成制备方法 | |
CN104447554A (zh) | 伊伐布雷定及其盐酸盐的制备方法 | |
CN108752224B (zh) | 一种醋酸赖氨酸原料药的制备方法 | |
CN103664512A (zh) | 一种制备高纯度1-氟萘的方法 | |
CN114014835A (zh) | 一种乙交酯的纯化工艺 | |
CN103772256B (zh) | 一种高纯度舒必利或其光学异构体的制备方法 | |
CN101633639B (zh) | 一种高纯度的氟罗沙星化合物 | |
CN112125842A (zh) | 一种从3-氰基吡啶废水中分离提纯烟酸的方法 | |
CN106631978B (zh) | 一种米格列奈中间体的合成工艺 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee |
Owner name: ZHEJIANG SHOUXIN PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME: SHOUXIN MEDICINE CHEMICALS CO., LTD., ZHEJIANG |
|
CP01 | Change in the name or title of a patent holder |
Address after: Hangzhou City, Zhejiang province 311227 Xiaoshan street Nanyang District No. 6 Jiang Er Lu. Patentee after: ZHEJIANG SHOUXIN PHARMACEUTICAL CO., LTD. Address before: Hangzhou City, Zhejiang province 311227 Xiaoshan street Nanyang District No. 6 Jiang Er Lu. Patentee before: Shouxin Medicine Chemicals Co., Ltd., Zhejiang |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20191203 Address after: 318000 No.7 Donghai 4th Avenue, linghaitoumengang New District, Linhai City, Taizhou City, Zhejiang Province Patentee after: Zhejiang Yongtai handxin Pharmaceutical Technology Co., Ltd Address before: Hangzhou City, Zhejiang province 311227 Xiaoshan street Nanyang District No. 6 Jiang Er Lu. Patentee before: ZHEJIANG SHOUXIN PHARMACEUTICAL CO., LTD. |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20200131 Address after: Xiaoshan District of Hangzhou City, Zhejiang province 311227 Zhejiang Nanyang Economic Development Zone No. 6 Jiang Er Lu Patentee after: ZHEJIANG SHOUXIN PHARMACEUTICAL CO., LTD. Address before: 318000 No.7 Donghai 4th Avenue, linghaitoumengang New District, Linhai City, Taizhou City, Zhejiang Province Patentee before: Zhejiang Yongtai handxin Pharmaceutical Technology Co., Ltd |