CN102218116A - Traditional Chinese medicine for treating diabetes and preparation method thereof - Google Patents
Traditional Chinese medicine for treating diabetes and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating diabetes and a preparation method thereof. The traditional Chinese medicine composition for treating diabetes has the advantages of obvious effect and small toxic or side effect, has the functions of preventing, controlling, relieving and curing diabetes, and can prevent the generation and development of diabetes complications. The traditional Chinese medicine composition for treating diabetes is characterized by comprising 2-8g of ginseng, 6-15g of radix astragali, 4-10g of cornel, 2-6% of angelica, 4-9g of wolfberry fruit, 8-10g of kudzu root, 4-8g of polygonatum, 2-8g of pupae, 30-50g of balsam pear and 1-6g of licorice root. The preparation method is characterized by comprising the following steps: extracting volatile oil from angelica, and extracting ginseng with alcohol; merging decoction dregs of angelica and ginseng with radix astragali, cornel, wolfberry fruit, kudzu root, polygonatum, pupae, balsam pear and licorice root; adding 10 times of water, extracting twice (two hours a time), and filtering; merging the two filtrates; concentrating the merged filtrate under reduced pressure at 60 DEG C until the relative density reaches about 1.15-1.20, adding 3 times of 75% ethanol, standing for 24 hours, and taking the supernatant for later use; drying the supernatant, and screening; and taking the undersize, mixing with the volatile oil of angelica for 30 minutes, granulating by a dry process, and finishing the granules.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation with Chinese medicine preparation and preparation method thereof, concrete is a kind of Chinese medicine preparation for the treatment of diabetes and preparation method thereof.
Background technology
Diabetes can be divided into constitutional and Secondary cases two classes.Clinical common majority is constitutional person, the cause of disease is not bright; Secondary cases person occupies the minority, though its ill reason can detect, its etiopathogenesis is not understood as yet.The modal secondary diabetes cause of disease is that pancreas excision entirely, chronic pancreatitis and some endocrinopathy institutes such as (as acromegaly, hypercortisolism, pheochromocytoma, hyperthyroidism) causes.
Specifically, the pathogeny of diabetes is relevant with following factors:
Diet: before bimillennium, the record of " interior warp " just relevant diabetes cause of disease.As " element is asked. a strange sick opinion piece of writing the 47 " and Ceng Yun: " this person must count the sweet and refreshing and many fertilizer of food also, the overeating greasy food bringing about internal heat, and the over-eating the food with sweet flavor bringing about abdominal distension is so its gas overflow transfers to and quenching one's thirst.”
Fat: the generation of diabetes and body constitution obesity also have relation.Why fat people easily sends out diabetes, and reason is many-sided.At first, the overweight people lacks physical exertion mostly, influences the metabolism of blood glucose, has increased the burden of islet cells; Secondly, overweight people's histoorgan is very inresponsive to insulin; This also can make islet cells increase burden; In addition, the overweight people is low and affinity is less to Insulin receptor INSR density on the adipocyte plasma membrane, insulin active a little less than.Above situation makes overweight people's onset diabetes rate exceed 2～3 times than normal type person.And the overweight people can increase more than 30 times.Many scholars point out that the universal rule of whole world diabetes prevalence is along with the increase of body weight is increased.
Heredity: on address, the overweight people easily suffers from diabetes, but according to clinical findings, young diabetics is generally not fat, its reason may be relevant with inherited genetic factors.Investigation finds that the onset diabetes rate among the diabetes patient relatives wants high than non-diabetic people relatives' onset diabetes rate; From twin children's onset diabetes history, diabetes almost take place in like-sexed twins person simultaneously, prove that diabetes have genetic predisposition.The traditional Chinese medical science is thought diabetes from the beginning of belonging to " hepatic and renal YIN deficiency " person then according to clinical findings, and its cause of disease is relevant with " congenital defect " mostly.Liver is that body the moon is used the dirty of sun, and main catharsis can be regulated the human body metabolism; Kidney controlling discharge and retention, kidney storing essence, the existing Excretion of renal tubules has Reabsorption again.Deficiecny of liver-YIN is hyperactivity of deficient fire then.The lung yin of burning, body fluid can not be failed cloth, so polydipsia and thirsty more than causes " on disappear "; Deficiency of kidney yin then astringency inducing is had no right, and does not precise and tinyly hide, so frequent micturition and sugariness is arranged causes " diabetes due to kidney-deficiency ".Clinical findings also has because of in the innate deficiency of YANG in the body person, but studies carefully the genus minority.Need to prove that diabetes generation and damaged by excess of seven emotions, chamber do not save also relation.
No matter due to which kind of reason, its pathogeny is how relevant with " interior-heat ".The thermal burn stomach-Yin is excessiveness of stomach-fire and rapid digestion of food and polyorexia (in disappear) then; The thermal burn lung yin is not compress and excessive thirst polydipsia (on disappear) of Tianjin then; Thermal burn kidney yin then astringency inducing is had no right and frequent micturition sweet in the mouth (diabetes due to kidney-deficiency).With the passing of time diabetes if delay, and deficiency of YIN affecting YANG can cause insufficiency of kidney-YANG; The glycosuria patient is also arranged, belong to innate deficiency of YANG in the body originally, onset of disease just has the symptom of insufficiency of kidney-YANG, and this can not know again.
Diabetes are a kind of chronic progressive diseases.Since carbohydrate metabolism, lipid metabolism, protein metabolism disturbance, neural, angiodystrophia, and Abwehrkraft des Koepers descends, and multiple complications can occur.
The traditional Chinese medical science early has understanding to the complication of diabetes, before 2,000 years, and " element is asked-the flaccidity opinion " Ceng Yun: " spleen-heat is thirst due to consumption of stomach fluid then, numbness, and sending out is muscular atrophy." the diabetes complicated peripheral neuritis performance of the similar doctor trained in Western medicine of this opinion." Medical Treasures of the Golden Chamber-aqueous vapor abnormal pulse card is also controlled " Ceng Yun: " edema of the lower eyelid resembling a silkworm---its people's performance is quenched one's thirst." the similar diabetes complicated glomerulosclerosis of this opinion.In the ancient literature for diabetes complication record maximum be carbuncle.Say as " General Treatise on the Cause and Symptoms of Diseases ": " its sick multiple carbuncle." also cloud of Thousand Golden Prescriptions: " people who quenches one's thirst, more and do not heal, often must consider have big carbuncle." clinical findings, pyogenic infections such as diabetes complicated furuncle, carbuncle are also often seen.It is reported that diabetes complicated furuncle, carbuncle person account for 10%～30%. of diabetics
On address, multiple complications can take place in diabetes.Common having is following several.
Furuncle, carbuncle: the diabetes patient is because Abwehrkraft des Koepers descends, and furthermore hyperglycemia increases plasma osmotic pressure and suppresses leukocytic phagocytic activity; The rising of blood sugar concentration helps the growth of some antibacterial again, because of the easy concurrent furuncle carbuncle of invention award.The traditional Chinese medical science thinks that with the passing of time the diabetes patient ill, positive QI-insufficiency, and evil poison is taken advantage of a weak point, and causes into this disease.Carbuncle is that a plurality of adjacent hair follicles and the acute festering type of affiliated sebaceous gland infect, and also can think that a plurality of furuncle and phyma merge skin, the hypodermic pyogenic infection that forms.The diabetes patient concurrent carbuncle be more common in adult type, good send out behind neck, back etc. located.Primary symptom is local red, swollen, hot, bitterly, boundary clear on every side, not becoming does not have the skin ulcer head before the pus and easily dissipates, the easy diabrosis of person that become pus, the back pus of bursting is sticky, being liable to cause wound healing, General Symptoms have heating, tremble with fear stand, leukocyte count increases etc.But to the later stage, its open sore part then is difficult to healing.
Cardiovascular pathological changes: the fat metabolic disturbance of diabetics is the important cause of disease that cardiovascular disease complications in diabetes becomes.Its basic pathology is arteriosclerosis and blood capillary basal membrane thickening, but the definite cause of disease and pathogenesis are not sure of.Diabetes complicated cardiovascular pathological changes mainly contains hypertension, hypertensive heart disease, coronary atherosclerotic heart disease etc., is the most serious problem of diabetes patient, accounts for more than 70% of diabetes patient's cause of death.
Edema: diabetes are from the beginning of belonging to the deficiency of kidney yin person, and are sick if with the passing of time do not heal, then can be, and it is also empty to cause kidney yang (spleen sun) because of deficiency of YIN affecting YANG, suffer from a deficiency of the kidney that it is entire unfavorable then to open, and functioning of bladder is not normal, and water liquid stops, and spreads unchecked brimmingly, forms edema.The edema of diabetic nephropathy belongs to this category.Generally be edema to occur after ill 10 years.Cardinal symptom is an anasarca, the edema below the waist very, the depression ， Yao Han of pressing is weak, clear urine in large amounts, the nocturia increased frequency, the complexion ash is dim, enlarged tongue and light is a little less than the deep-thready pulse.Doctor trained in Western medicine is thought diabetes complicated edema, mainly is because glomerular capillary and small artery infringement, and protein disappears from urine, due to plasma protein reduces.
Sexual impotence: diabetes complicated sexual impotence person is clinical to be seen more.Main cause is decline of the fire from the gate of life or deficiency of kidney-essence, and is ill long-term uncured in addition, excessively melancholy, also can bring out sexual impotence.Doctor trained in Western medicine think hypophysis _ gonad system exception, peripheral circulation disorders, vegetative nerve functional disturbance that diabetes are followed be diabetes complicated sexual impotence main diseases because of.Many function of dominants of diabetes sexual impotence person sexually transmitted disease (STD) becomes, and mainly shows as impotence or act and not hard, and the women libido then occurs and descends, and spiritual flaccidity wastes, or fears timid more.
Look illiteracy: the diabetes complicated illiteracy person of looking very common, especially aged patient.Main disease is the conscious blurred vision of patient, visual deterioration, in addition blind.Its pathogenesis is that Liver and kidney is deficient, and vital essence can not sending nutrient upward to eye.Some belongs to the card that turbid general, the clear key of expectorant is covered.Two doctors think and cause that diabetes complicated blind main cause is that retina changes.
Numb hand and foot: diabetes complicated numb hand and foot person is also very common.Mainly show as brothers' far-end feeling of numbness or prickling sensation (generally being that lower limb are more obvious than upper limb), be to your property, as " glove "; Or " ankle socks " type sensory disturbance, night is more obvious, the lower limb weakness, and it is difficult to stand up, walk, and what have accompanies by muscle atrophia, ankle edema.Belong to " myopathy " or " beriberi " category.Its pathogenesis mostly is deficiency of both the liver and kidney, and essence and blood can not moisten supports meridians muscle blood.Also can be because of the sweet fertilizer of surfeit, impairing the spleen and stomach, turbid damp multiple abscess extremity, heap soil or fertilizer over and around the roots is held back meridians and is caused.Doctor trained in Western medicine thinks that this belongs to diabetic peripheral neuropathy.How because of due to Developmental and Metabolic Disorder and vitamin deficiency, the angiopathy, especially based on Developmental and Metabolic Disorder.
Hemiplegia: the diabetes later stage often hemiplegia can occur.Disease is seen hemiplegia, facial hemiparalysis, or dysphonia.Weight person can lose consciousness the servant suddenly, syncope.Its pathogenesis mostly be rest inappropriate, imbalance of YIN and YANG, kidney unit is solid, stirring-up of pathogenic wind in the interior resulting from deficiency is held granular turbid closing due to the cloudy clear key under the arm.Also can lose greatly because of healthy energy, it is capable to promote blood, so that the turbid venation of the stasis of blood, and the muscle arteries and veins loses supports.Doctor trained in Western medicine thinks that the mechanism of diabetes complicated hemiplegia is relevant with cerebrovascular disease: be mainly cerebral infarction.
Diabetes still can concurrent pulmonary tuberculosis, hyperlipemia, fatty liver etc., because length is limited, will not introduce at this.
The traditional Chinese medical science is according to polydipsia, polyphagia, three main symptoms of polyuria, diabetes is divided into disappear, in disappear, diabetes due to kidney-deficiency three types.With thirsty polydipsia is that the main symptom person belongs to and disappears; With easy hungry polyphagia is to disappear during primary symptom person belongs to; With polyuria (particularly frequent urination at night) is that primary symptom is for belonging to diabetes due to kidney-deficiency.Diabetes spp diabetes category, therefore, the traditional Chinese medical science can be with reference to above typing to the diagnosis and treatment of diabetes.
Doctor trained in Western medicine has several different methods to the typing of diabetes.Wherein great majority are according to the onset character classification by age, can be divided into juvenile form and veteran form two classes.Juvenile form (claiming instability mode again) patient wants onset before 15～18 years old more, and clinical more rare, father or mother have diabetic history more, and the cause of disease belongs to inherited genetic factors more, and onset is more rapid, and condition of illness is obvious, and body weight often significantly alleviates, and various complication are also more early to be occurred.
Adult (claiming stable type again) patient many after 40 years old onset, clinically comparatively see have cloud to account for more than 75% of diabetes more.Minority has family history, and onset is slow, mild symptoms, and blood glucose fluctuation is little, and it is slower that complication occurs, but cardiovascular pathological changes serious (as retinal arteriosclerosis, coronary heart disease, cerebrovascular accident etc.) often goes to a doctor because of vascular lesion occurring, and just diabetes have been suffered from discovery.
Though the clinical medicine that is used for the treatment of diabetes can improve diabetics symptoms such as " three-many-one-littles " at present, the decline of energy blood sugar control index, but these mostly are chemical drugs greatly, also hypoglycemic reaction can take place sometimes, and taking for a long time has certain infringement to human body.
Summary of the invention
The present invention is for solving the problems of the technologies described above, with Chinese medicine composition that the treatment diabetes that a kind of effect is remarkable, toxic and side effects is little are provided and preparation method thereof, have prevention, control, alleviate and cure the effect of diabetes, prevent the generation and the development of diabetic complication.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is: the Chinese medicine medicine of treatment diabetes is characterized in that: the Chinese medicine medicine is formed as follows in weight ratio: Radix Ginseng 2-8g, Radix Astragali 6-15g, Fructus Corni 4-10g, Radix Angelicae Sinensis 2-6g, Fructus Lycii 4-9g, Radix Puerariae 8-20g, Rhizoma Polygonati Odorati 4-8g, Pupa bombycis 2-8g, Fructus Momordicae charantiae 30-50g, Radix Glycyrrhizae 1-6g.Described medicament is diffusing, sheet, ball, capsule, electuary, oral liquid and honeyed pill.
The preparation method of the Chinese medicine medicine of treatment diabetes is characterized in that: Radix Angelicae Sinensis extracts volatile oil earlier, and Radix Ginseng adopts alcohol extraction, gets alcohol extract; The medicinal residues of Radix Angelicae Sinensis and Radix Ginseng and the Radix Astragali, Fructus Corni, Fructus Lycii, Radix Puerariae, Rhizoma Polygonati Odorati, Pupa bombycis, Fructus Momordicae charantiae, Radix Glycyrrhizae 8 flavor medicines merge, and add 10 times of water gagings of medical material and extract twice, each two hours, filter; Merge filtrate twice; 60 ℃, during vacuum 0.08Mpa, the filtrate decompression after merging is concentrated into relative density is about 1.15-1.20, adds 3 times and measures 75% ethanol and left standstill 24 hours, it is standby to get supernatant; The Radix Ginseng ethanol extract adds in the supernatant, and oven dry is again pulverized, and sieves; Extracting screen underflow, Radix Angelicae Sinensis volatile oil mix dry granulation after 30 minutes, granulate.If make tablet, tabletting then, coating is promptly.
This formula for a product is according to the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs principle of the traditional Chinese medical science, from promoting the production of body fluid to quench thirst, clearing heat and relieving fidgetness, YIN nourishing support kidney, QI invigorating and, the strengthening vital QI to eliminate pathogenic factors prescription of starting with.Join strongly invigorating primordial QI, invigorating the spleen to benefit the lung in the prescription greatly, promote the production of body fluid, calm the nerves; Radix Astragali invigorating QI to consolidate the body surface resistance, removing interior-heat are quenched one's thirst; Fructus Corni liver and kidney tonifying, essence astringing and desertion stemming; This three flavor share can work in coordination with QI invigorating, strengthening vital QI to eliminate pathogenic factors; Chinese angelica blood supplementing is invigorated blood circulation, loosening bowel to relieve constipation; Fructus Lycii nourishing the liver and kidney, replenishing vital essence to improve eyesight; Radix Puerariae and Rhizoma Polygonati Odorati promoting the production of body fluid to quench thirst; The Pupa bombycis spleen invigorating, only quench one's thirst, tranquillizing the mind by relieving convulsion, benefit is smart supporing yang; Fructus Momordicae charantiae nourishing blood and invigorating qi, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.Radix Ginseng, the Radix Astragali, Fructus Corni and Radix Angelicae Sinensis, Fructus Momordicae charantiae share, and can promote the effect of Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling and Fructus Momordicae charantiae nourishing blood and invigorating qi, reach the purpose of qi and blood tonifying, promote the hormonal system function, make the islet cells excreting insulin; The Fructus Lycii enriching yin and nourishing kidney, and can alleviate the dry of Radix Ginseng, the Radix Astragali; Radix Puerariae, Rhizoma Polygonati Odorati strengthening the spleen and stomach promoting the production of body fluid to quench thirst, the disease that can separate the thirsty polydipsia of diabetics; Pupa bombycis has the history of edible blood sugar lowering for many years in China, can propose effective sugar-lowering components after extracting, and promotes insulin secretion, blood sugar lowering; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.This ten flavors medicine share, and can thoroughly cure type ii diabetes.
This formula for a product is made up of medicine food homologous raw materials, all meets the requirement of drug safety from the consumption of effective compatibility and safety, and does not have incompatibility, so this prescription is safe and effective.
Medicine of the present invention is oral, every day 3 times, and each 2-4 gram finished product, 40 days is a course of treatment, and common 1-2 course of treatment is effective, and pertinacious disease needs 3-4 the course of treatment.
Clinical research:
Fasting glucose relatively before and after the treatment: (mmol/L)
After treating before the number treatment
216 12.62±2.67 5.31±1.18
Blood glucose compared in two hours after the meal:
After treating before the number treatment
216 15.89±4.21 7.63±2.27
Produce effects 136 examples, obvious effective rate 63%; Effective 80 examples, effective percentage 37%; Invalid 0 example, inefficiency are 0.
Description of drawings
Fig. 1 is the process chart of preparation method of the Chinese medicine medicine of treatment diabetes.
The specific embodiment
Embodiment 1
Get Radix Ginseng 2g, Radix Astragali 6g, Fructus Corni 4g, Radix Angelicae Sinensis 2g, Fructus Lycii 4g, Radix Puerariae 8g, Rhizoma Polygonati Odorati 4g, Pupa bombycis 2g, Fructus Momordicae charantiae 30g, Radix Glycyrrhizae 1g.Radix Angelicae Sinensis is put into extraction pot and extracted volatile oil, and is standby, and the ethanol extraction of 10 times of amounts 75% of Radix Ginseng adding 2 hours gets alcohol extract, and is standby; The medicinal residues of Radix Angelicae Sinensis and Radix Ginseng and the Radix Astragali, Fructus Corni, Fructus Lycii, Radix Puerariae, Rhizoma Polygonati Odorati, Pupa bombycis, Fructus Momordicae charantiae, Radix Glycyrrhizae 8 flavor medicines merge the purified water extraction of 10 times of amounts of adding medical material 2 times, each two hours.Reuse 200 order stainless steel sift net filtrations.Merge filtrate twice, above-mentioned filtrate is added in the concentrator concentrating under reduced pressure.60 ℃ of thickening temperatures, vacuum 0.08Mpa is concentrated into relative density and is about 1.15-1.20, gets extractum.The ethanol that gained extractum is added 3 times of amounts 75% left standstill 24 hours, and it is standby to get supernatant, and residue discards.The Radix Ginseng ethanol extract adds in the supernatant, reclaims ethanol, gets thick paste.After thick paste placed sterilization vacuum drying oven (vacuum 0.08Mpa, 60 ℃) oven dry, put in the efficient universal pulverizer and pulverize, cross 80 mesh sieves, powder gets dry extract.Volatile oil is added in the dried cream powder, to mixer, mixed 30 minutes, use dry granulation behind the mix homogeneously, cross 20 mesh sieve granulate, send subsequent processing.Can be proportionally and medical adjuvant uniform mixing commonly used, make various dosage forms, the packing warehouse-in.
Embodiment 2
Get Radix Ginseng 6g, Radix Astragali 10g, Fructus Corni 7g, Radix Angelicae Sinensis 4g, Fructus Lycii 7g, Radix Puerariae 15g, Rhizoma Polygonati Odorati 6g, Pupa bombycis 5g, Fructus Momordicae charantiae 40g, Radix Glycyrrhizae 3g.Radix Angelicae Sinensis is put into extraction pot and extracted volatile oil, and is standby, and the ethanol extraction of 10 times of amounts 75% of Radix Ginseng adding 2 hours gets alcohol extract, and is standby; The medicinal residues of Radix Angelicae Sinensis and Radix Ginseng and the Radix Astragali, Fructus Corni, Fructus Lycii, Radix Puerariae, Rhizoma Polygonati Odorati, Pupa bombycis, Fructus Momordicae charantiae, Radix Glycyrrhizae 8 flavor medicines merge the purified water extraction of 10 times of amounts of adding medical material 2 times, each two hours.Reuse 200 order stainless steel sift net filtrations.Merge filtrate twice, above-mentioned filtrate is added in the concentrator concentrating under reduced pressure.60 ℃ of thickening temperatures, vacuum 0.08Mpa is concentrated into relative density and is about 1.15-1.20, gets extractum.The ethanol that gained extractum is added 3 times of amounts 75% left standstill 24 hours, and it is standby to get supernatant, and residue discards.The Radix Ginseng ethanol extract adds in the supernatant, reclaims ethanol, gets thick paste.After thick paste placed sterilization vacuum drying oven (vacuum 0.08Mpa, 60 ℃) oven dry, put in the efficient universal pulverizer and pulverize, cross 80 mesh sieves, powder gets dry extract.Volatile oil is added in the dried cream powder, to mixer, mixed 30 minutes, use dry granulation behind the mix homogeneously, cross 20 mesh sieve granulate, send subsequent processing.Can be proportionally and medical adjuvant uniform mixing commonly used, make various dosage forms, the packing warehouse-in.
Embodiment 3
Get Radix Ginseng 8g, Radix Astragali 15g, Fructus Corni 10g, Radix Angelicae Sinensis 6g, Fructus Lycii 9g, Radix Puerariae 20g, Rhizoma Polygonati Odorati 8g, Pupa bombycis 8g, Fructus Momordicae charantiae 50g, Radix Glycyrrhizae 6g.Radix Angelicae Sinensis is put into extraction pot and extracted volatile oil, and is standby, and the ethanol extraction of 10 times of amounts 75% of Radix Ginseng adding 2 hours gets alcohol extract, and is standby; The medicinal residues of Radix Angelicae Sinensis and Radix Ginseng and the Radix Astragali, Fructus Corni, Fructus Lycii, Radix Puerariae, Rhizoma Polygonati Odorati, Pupa bombycis, Fructus Momordicae charantiae, Radix Glycyrrhizae 8 flavor medicines merge the purified water extraction of 10 times of amounts of adding medical material 2 times, each two hours.Reuse 200 order stainless steel sift net filtrations.Merge filtrate twice, above-mentioned filtrate is added in the concentrator concentrating under reduced pressure.60 ℃ of thickening temperatures, vacuum 0.08Mpa is concentrated into relative density and is about 1.15-1.20, gets extractum.The ethanol that gained extractum is added 3 times of amounts 75% left standstill 24 hours, and it is standby to get supernatant, and residue discards.The Radix Ginseng ethanol extract adds in the supernatant, reclaims ethanol, gets thick paste.After thick paste placed sterilization vacuum drying oven (vacuum 0.08Mpa, 60 ℃) oven dry, put in the efficient universal pulverizer and pulverize, cross 80 mesh sieves, powder gets dry extract.Volatile oil is added in the dried cream powder, to mixer, mixed 30 minutes, use dry granulation behind the mix homogeneously, cross 20 mesh sieve granulate, send subsequent processing.Can be proportionally and medical adjuvant uniform mixing commonly used, make various dosage forms, the packing warehouse-in.
Though disclosed the preferred embodiments of the present invention for explanation; but those of ordinary skill in the art understands; under the situation that does not break away from claims institute's restricted portion of the present invention and spirit, various improvement, to increase and substitute all be possible, all within protection scope of the present invention.
Claims (4)
1. Chinese medicine medicine for the treatment of diabetes is characterized in that: the Chinese medicine medicine is formed as follows in weight ratio: Radix Ginseng 2-8g, Radix Astragali 6-15g, Fructus Corni 4-10g, Radix Angelicae Sinensis 2-6g, Fructus Lycii 4-9g, Radix Puerariae 8-20g, Rhizoma Polygonati Odorati 4-8g, Pupa bombycis 2-8g, Fructus Momordicae charantiae 30-50g, Radix Glycyrrhizae 1-6g.
2. the Chinese medicine medicine of treatment diabetes as claimed in claim 1 is characterized in that: described medicament is diffusing, sheet, ball, capsule, electuary, oral liquid and honeyed pill.
3. the preparation method of the Chinese medicine medicine of treatment diabetes as claimed in claim 1 is characterized in that: Radix Angelicae Sinensis extracts volatile oil earlier, and Radix Ginseng adopts alcohol extraction, gets alcohol extract; The medicinal residues of Radix Angelicae Sinensis and Radix Ginseng and the Radix Astragali, Fructus Corni, Fructus Lycii, Radix Puerariae, Rhizoma Polygonati Odorati, Pupa bombycis, Fructus Momordicae charantiae, Radix Glycyrrhizae 8 flavor medicines merge, and add 10 times of water gagings of medical material and extract twice, each two hours, filter; Merge filtrate twice; 60 ℃, during vacuum 0.08Mpa, the filtrate decompression after merging is concentrated into relative density is about 1.15-1.20, adds 3 times and measures 75% ethanol and left standstill 24 hours, it is standby to get supernatant; The Radix Ginseng ethanol extract adds in the supernatant, and oven dry is again pulverized, and sieves; Extracting screen underflow, Radix Angelicae Sinensis volatile oil mix dry granulation after 30 minutes, granulate.
4. the preparation method of the Chinese medicine medicine of treatment diabetes as claimed in claim 3 is characterized in that: make diffusing, sheet, ball, capsule, granule, oral liquid and honeyed pill.
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| CN103263580A (en) * | 2013-04-29 | 2013-08-28 | 青岛市市立医院 | Traditional Chinese medicine composition for treating diabetes |
| CN103933282A (en) * | 2013-01-18 | 2014-07-23 | 曾祥菲 | Traditional Chinese medicine preparation for treating diabetes |
| CN104873837A (en) * | 2015-06-02 | 2015-09-02 | 徐倩 | Traditional Chinese medicine granular preparation and preparing method thereof |
| CN105145994A (en) * | 2015-09-23 | 2015-12-16 | 安徽阳光药业有限公司 | Health care Chinese herb tea capable of adjusting blood glucose and preparation method thereof |
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| 《山东中医杂志》 19961220 王如沾 糖尿病中药筛选组方思路 , 第12期 * |
| 《继续医学教育》 20060730 赵进喜 糖尿病及其并发症的中医诊治 , 第19期 * |
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| CN103933282B (en) * | 2013-01-18 | 2017-08-01 | 曾祥菲 | A kind of Chinese medicinal capsule for treating diabetes |
| CN103263580A (en) * | 2013-04-29 | 2013-08-28 | 青岛市市立医院 | Traditional Chinese medicine composition for treating diabetes |
| CN104873837A (en) * | 2015-06-02 | 2015-09-02 | 徐倩 | Traditional Chinese medicine granular preparation and preparing method thereof |
| CN105145994A (en) * | 2015-09-23 | 2015-12-16 | 安徽阳光药业有限公司 | Health care Chinese herb tea capable of adjusting blood glucose and preparation method thereof |
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