CN1660288A - Capsule of treating gall-stone and cholecystitis, and preparation method - Google Patents
Capsule of treating gall-stone and cholecystitis, and preparation method Download PDFInfo
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- CN1660288A CN1660288A CN 200410092410 CN200410092410A CN1660288A CN 1660288 A CN1660288 A CN 1660288A CN 200410092410 CN200410092410 CN 200410092410 CN 200410092410 A CN200410092410 A CN 200410092410A CN 1660288 A CN1660288 A CN 1660288A
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- cholecystitis
- cholelithiasis
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Abstract
A Chinese medicine in the form of capsule for treating cholecystitis and cholelithiasis is prepared from 10 Chinese-medicinal materials including oriental wormwood, lysimachia, red peony root, rhubarb, etc through decocting twice, filtering, dissolving sodium sulphate in it, filtering, concentrating, drying, pulverizing and loading in capsules.
Description
One, technical field
The invention belongs to a kind of treatment cholecystitis, the Chinese Traditional Medicines of cholelithiasis are specifically related to a kind of capsule and manufacture method thereof for the treatment of cholelithiasis, cholecystitis.
Two, background technology
There is very abundant pools of traditional Chinese medicine in China, but awaits to discover and use.The a lot of original very effective Chinese medicinal formulaes of China, because of being subjected to the influence of factors such as technology of preparing, preparation technology and dosage form packing, greatly overslaugh in the sale of international market, improve the research of raising pharmacy new technique novel form for this reason, also be imminent.With regard to the calculus choleretic granules, bigger again on dose, bitter again peppery on mouthfeel, take very inconvenience.Become the patient who suffers from diabetes simultaneously and avoid and take medicine, its range of application is restricted.For example the patent No. is that 01141341 Chinese medicine also exists foreign odor, and the drug volatilization effect is fast, and drug effect is not lasting, shortcomings such as amount matter instability.
Three, summary of the invention
The present invention will solve existing manufacturing process and dosage form is taken inconvenience, hinders characteristic medicine and moves towards the international market, makes diabetics because medicine contains the problem that sugar can not be taken.
The technical scheme that the present invention realizes: a kind of capsule for the treatment of cholelithiasis, cholecystitis, it is to be made by the following weight proportion raw material: Herba Artemisiae Scopariae 450-610 part, Radix Bupleuri (processed with vinegar) 110-190 part, Herba Lysimachiae 410-590 part, Radix Gentianae 208-295 part, Radix Paeoniae Rubra 102-195 part, Radix Curcumae 102-188 part, Pollen Typhae 120-210 part, Radix Et Rhizoma Rhei 115-175 part, Oletum Trogopterori 125-215 part, Natrii Sulfas 85-115 part.Dosage form of the present invention can also be soft capsule, microcapsule, tablet, concentrated pill or drop pill.A kind of capsular preparation method for the treatment of cholelithiasis, cholecystitis, above ten flavor medicines are boiled except that Natrii Sulfas and carry twice, 2 hours for the first time, 1.5 hours for the second time, merging filtrate, Natrii Sulfas immersed in the filtrate dissolve, filter, filtrate is concentrated to the extractum that relative density is 1.20-1.25 (68 ℃), carries out constant temperature (40～50 ℃) drying, pulverize then, in incapsulating promptly.
The present invention compares with prior art has following beneficial effect: this medicine liver-smoothing, qi-regulating, cholagogic and lithagogue is used for cholecystitis and cholelithiasis.The medicine that refines is made dosage forms such as capsule or soft capsule, microcapsule, tablet, drop pill, be convenient to the use of popularity, reduced the bitter peppery of mouthfeel when taking medicine, not only brought superiority, and also brought the advantage of market sale to pharmacy corporation to the patient.
Treatment gallbladder gallbladder inflammation, cholelithiasis typical case medical record are for example
Medical record gives an example 1
Zhang, the man 45 years old, likes the delicious food savoury, obesity usually.Felt upper right abdomen dull pain discomfort before 2 weeks after meal, carrying out property increases the weight of, and pain connects the shoulder back of the body, can not put down for sleeping inly, and companion's nausea and vomiting, is examined and is cholelithiasis through CT examination in local hospital, comes here to seek medical advice through therapeutic effect is not good.Examine and see: face dolorosa, tired mind, obesity, light red tongue, greasy fur are yellow slightly, slippery and rapid pulse.Dialectical is the card of dampness-heat in the liver and gallbladder.Control with clearing away heat-damp and promoting diuresis depressed liver-energy dispersing and function of gallbladder promoting, eliminating stagnation calculus.Give capsule every day three times of clothes treatment cholelithiasis, cholecystitis, each 4,1 week was 1 course of treatment.And add Chinese medicine decoction: Radix Gentianae, Pericarpium Citri Reticulatae, each 15g of Rhizoma Pinelliae Preparatum, Herba Artemisiae Scopariae 20g is decocted in water for oral dose 1 pair of every day, takes seven pairs continuously, cuts out Chinese medicine decoction from the 2nd course of treatment, changes the capsule of single clothes treatment cholelithiasis, cholecystitis; After the 3rd course of treatment: patient's spirit is good, does not have uncomfortable symptom, take the 4th course of treatment after, carry out ultrasound diagnosis, the cholelithiasis shade disappears.
Medical record gives an example 2
Zhu, the woman 50 years old, because of ictal epigastrium pain 1 year, aggravates 5 days in first visit on March 13 in 2002.After the morbidity once with controlling " gastropathy " medicine, poor effect.Examine and see: epigastrium pain, the paroxysmal outbreak, and the shoulder back of the body radiates to the right, accompanies fever with aversion to cold, it is indigestion and loss of appetite to feel sick, the bitter taste gastral cavity expands, constipation, and a few days 1 row, yellowish urine is red.Experience: 38.4 ℃ of body temperature.Sanity, painful sickly complexion, the slight xanthochromia of sclera, upper right abdominal pressure pain is obvious, the Murphy's sign positive, red tongue margin has petechia, yellow and greasy fur, stringy and rolling pulse.Lab testing: blood WBC1.35 * 10
9/ L, N0.79, L0.12.B ultrasonic shows: gallbladder wall is fuzzy, and entrant sound is poor, in see many pieces of light group accompanying sound shadows, maximum 0.6cm * 17cm, choledochectasia, in see 2 pieces of light group accompanying sound shadows that are respectively 0.4cm * 0.5cm, 6cm * 0.4cm.Tcm diagnosis: dampness-heat in the liver and gallbladder, blood-stasis syndrome.Western medicine diagnose: cholelithiasis, cholecystitis.Adopt Herba Artemisiae Scopariae 30g, Fructus Gardeniae 10g, Radix Et Rhizoma Rhei 4g is decocted in water for oral dose 1 dose of every day, serve on 6 days.The capsule of the cholelithiasis of clothes treatment simultaneously, cholecystitis, every day 3 times, each 4, cold and heat disappear after 5 days, and upper right abdomen pain, gastral cavity expand, bitter taste is felt sick, and sense obviously alleviates, and it is normal that hemogram recovers.Continued to take 7 days, all diseases disappear, and health check-up depletion of YANG gonosome is levied.After taking medicine again 5 days, discharge more than 10 piece of calculus size successively, the 6cm * 0.7cm of volume maximum, minimum 0.1cm-0.2cm.After spending 7 days again, do ultrasound diagnosis, calculus is all discharged.Continue to take the capsule of treatment cholelithiasis, cholecystitis, not recurrence in 1 year is followed up a case by regular visits in drug withdrawal after 1 month.
Four, the specific embodiment
Embodiment 1
A kind of capsule for the treatment of cholelithiasis, cholecystitis, it is to be made by the following weight proportion raw material: Herba Artemisiae Scopariae 500 grams, Radix Bupleuri (processed with vinegar) 150 grams, Herba Lysimachiae 500 grams, Radix Gentianae 250 grams, Radix Paeoniae Rubra 150 grams, Radix Curcumae 150 grams, Pollen Typhae 150 grams, Radix Et Rhizoma Rhei 150 grams, Oletum Trogopterori 150 grams, Natrii Sulfas 100 grams.A kind of capsular preparation method for the treatment of cholelithiasis, cholecystitis, above ten flavor medicines are boiled except that Natrii Sulfas and carry twice, 2 hours for the first time, 1.5 hours for the second time, merging filtrate, Natrii Sulfas immersed in the filtrate dissolve, filter, filtrate is concentrated to the extractum that relative density is 1.20 (68 ℃), carry out 45 ℃ of dryings of constant temperature, pulverize then, promptly, specification is every 0.5 gram in 612 capsules of packing into.Usage: oral one time three, three times on the one.
Embodiment 2
A kind of capsule for the treatment of cholelithiasis, cholecystitis, it is to be made by the following weight proportion raw material: Herba Artemisiae Scopariae 450 grams, Radix Bupleuri (processed with vinegar) 110 grams, Herba Lysimachiae 410 grams, Radix Gentianae 208 grams, Radix Paeoniae Rubra 102 grams, Radix Curcumae 110 grams, Pollen Typhae 120 grams, Radix Et Rhizoma Rhei 115 grams, Oletum Trogopterori 125 grams, Natrii Sulfas 85 grams.A kind of capsular preparation method for the treatment of cholelithiasis, cholecystitis, above ten flavor medicines are boiled except that Natrii Sulfas and carry twice, 2 hours for the first time, 1.5 hours for the second time, merging filtrate, Natrii Sulfas immersed in the filtrate dissolve, filter, filtrate is concentrated to the extractum that relative density is 1.23 (68 ℃), carry out 48 ℃ of dryings of constant temperature, pulverize then, promptly, specification is every 0.5 gram in 580 capsules of packing into.Usage: oral one time three, three times on the one.
Embodiment 3
A kind of capsule for the treatment of cholelithiasis, cholecystitis, it is to be made by the following weight proportion raw material: Herba Artemisiae Scopariae 610 grams, Radix Bupleuri (processed with vinegar) 190 grams, Herba Lysimachiae 590 grams, Radix Gentianae 295 grams, Radix Paeoniae Rubra 195 grams, Radix Curcumae 188 grams, Pollen Typhae 210 grams, Radix Et Rhizoma Rhei 175 grams, Oletum Trogopterori 215 grams, Natrii Sulfas 115 grams.A kind of capsular preparation method for the treatment of cholelithiasis, cholecystitis, above ten flavor medicines are boiled except that Natrii Sulfas and carry twice, 2 hours for the first time, 1.5 hours for the second time, merging filtrate, Natrii Sulfas immersed in the filtrate dissolve, filter, filtrate is concentrated to the extractum that relative density is 1.25 (68 ℃), carry out 40 ℃ of dryings of constant temperature, pulverize then, promptly, specification is every 0.5 gram in 756 capsules of packing into.Usage: oral one time three, three times on the one.
Claims (3)
1, a kind of capsule for the treatment of cholelithiasis, cholecystitis, it is characterized in that: it is to be made by the following weight proportion raw material: Herba Artemisiae Scopariae 450-610 part, Radix Bupleuri (processed with vinegar) 110-190 part, Herba Lysimachiae 410-590 part, Radix Gentianae 208-295 part, Radix Paeoniae Rubra 102-195 part, Radix Curcumae 102-188 part, Pollen Typhae 120-210 part, Radix Et Rhizoma Rhei 115-175 part, Oletum Trogopterori 125-215 part, Natrii Sulfas 85-115 part.
2, a kind of capsule for the treatment of cholelithiasis, cholecystitis according to claim 1, it is characterized in that: dosage form can also be soft capsule, microcapsule, tablet, concentrated pill or drop pill.
3, a kind of capsular preparation method for the treatment of cholelithiasis, cholecystitis, it is characterized in that: it is to be made by the following weight proportion raw material: Herba Artemisiae Scopariae 450-610 part, Radix Bupleuri (processed with vinegar) 110-190 part, Herba Lysimachiae 410-590 part, Radix Gentianae 208-295 part, Radix Paeoniae Rubra 102-195 part, Radix Curcumae 102-188 part, Pollen Typhae 120-210 part, Radix Et Rhizoma Rhei 115-175 part, Oletum Trogopterori 125-215 part, Natrii Sulfas 85-115 part; A kind of capsular preparation method for the treatment of cholelithiasis, cholecystitis, above ten flavor medicines are boiled except that Natrii Sulfas and carry twice, 2 hours for the first time, 1.5 hours for the second time, merging filtrate, Natrii Sulfas immersed in the filtrate dissolve, filter, filtrate is concentrated to the extractum that relative density is 1.20-1.25 (68 ℃), carries out constant temperature (40～50 ℃) drying, pulverize then, in incapsulating promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410092410 CN1660288A (en) | 2004-12-13 | 2004-12-13 | Capsule of treating gall-stone and cholecystitis, and preparation method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200410092410 CN1660288A (en) | 2004-12-13 | 2004-12-13 | Capsule of treating gall-stone and cholecystitis, and preparation method |
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| CN1660288A true CN1660288A (en) | 2005-08-31 |
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| CN 200410092410 Pending CN1660288A (en) | 2004-12-13 | 2004-12-13 | Capsule of treating gall-stone and cholecystitis, and preparation method |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100346821C (en) * | 2005-10-17 | 2007-11-07 | 胡进前 | Medicinal capsule for treating liver and gallbladder diseases and its preparing process |
| CN103100049A (en) * | 2013-01-30 | 2013-05-15 | 安徽华佗国药股份有限公司 | Traditional Chinese medicine preparation for treating gall-stone and cholecystitis, and preparation method thereof |
| CN103181968A (en) * | 2013-04-11 | 2013-07-03 | 上海浦东高星生物技术研究所 | Cholagogue urinary calculus removing pill |
| CN105079683A (en) * | 2014-05-13 | 2015-11-25 | 广东奇灵制药有限公司 | Medicine composition with calculus removing and bladder relieving effects and method for preparing medicine composition |
-
2004
- 2004-12-13 CN CN 200410092410 patent/CN1660288A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100346821C (en) * | 2005-10-17 | 2007-11-07 | 胡进前 | Medicinal capsule for treating liver and gallbladder diseases and its preparing process |
| CN103100049A (en) * | 2013-01-30 | 2013-05-15 | 安徽华佗国药股份有限公司 | Traditional Chinese medicine preparation for treating gall-stone and cholecystitis, and preparation method thereof |
| CN103181968A (en) * | 2013-04-11 | 2013-07-03 | 上海浦东高星生物技术研究所 | Cholagogue urinary calculus removing pill |
| CN105079683A (en) * | 2014-05-13 | 2015-11-25 | 广东奇灵制药有限公司 | Medicine composition with calculus removing and bladder relieving effects and method for preparing medicine composition |
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