CN101321567A - 利用集成多柱色谱制备化学品和药品的方法 - Google Patents
利用集成多柱色谱制备化学品和药品的方法 Download PDFInfo
- Publication number
- CN101321567A CN101321567A CNA2005800246655A CN200580024665A CN101321567A CN 101321567 A CN101321567 A CN 101321567A CN A2005800246655 A CNA2005800246655 A CN A2005800246655A CN 200580024665 A CN200580024665 A CN 200580024665A CN 101321567 A CN101321567 A CN 101321567A
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- valve
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Images
Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K27/00—Construction of housing; Use of materials therefor
- F16K27/003—Housing formed from a plurality of the same valve elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
- B01D15/1842—Simulated moving beds characterized by apparatus features
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B11/00—Connecting constructional elements or machine parts by sticking or pressing them together, e.g. cold pressure welding
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
- F16D1/00—Couplings for rigidly connecting two coaxial shafts or other movable machine elements
- F16D1/06—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end
- F16D1/064—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end non-disconnectable
- F16D1/068—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end non-disconnectable involving gluing, welding or the like
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
- F16D3/00—Yielding couplings, i.e. with means permitting movement between the connected parts during the drive
- F16D3/16—Universal joints in which flexibility is produced by means of pivots or sliding or rolling connecting parts
- F16D3/26—Hooke's joints or other joints with an equivalent intermediate member to which each coupling part is pivotally or slidably connected
- F16D3/38—Hooke's joints or other joints with an equivalent intermediate member to which each coupling part is pivotally or slidably connected with a single intermediate member with trunnions or bearings arranged on two axes perpendicular to one another
- F16D3/382—Hooke's joints or other joints with an equivalent intermediate member to which each coupling part is pivotally or slidably connected with a single intermediate member with trunnions or bearings arranged on two axes perpendicular to one another constructional details of other than the intermediate member
- F16D3/387—Fork construction; Mounting of fork on shaft; Adapting shaft for mounting of fork
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/42—Flow patterns using counter-current
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
- F16D1/00—Couplings for rigidly connecting two coaxial shafts or other movable machine elements
- F16D1/06—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end
- F16D2001/062—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end characterised by adaptors where hub bores being larger than the shaft
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/6851—With casing, support, protector or static constructional installations
- Y10T137/7043—Guards and shields
- Y10T137/7062—Valve guards
Landscapes
- General Engineering & Computer Science (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Mechanical Engineering (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sustainable Development (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Lift Valve (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210551546.7A CN103157294B (zh) | 2004-05-21 | 2005-05-14 | 利用集成多柱色谱制备化学品和药品的方法 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE200410025000 DE102004025000A1 (de) | 2004-05-21 | 2004-05-21 | Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie |
DE102004025000.6 | 2004-05-21 | ||
PCT/EP2005/005313 WO2005113101A2 (de) | 2004-05-21 | 2005-05-14 | Verfahren zur herstellung von chemischen und pharmazeutischen produkten mit integrierter mehrsäulen-chromatographie |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210551546.7A Division CN103157294B (zh) | 2004-05-21 | 2005-05-14 | 利用集成多柱色谱制备化学品和药品的方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101321567A true CN101321567A (zh) | 2008-12-10 |
CN101321567B CN101321567B (zh) | 2013-03-06 |
Family
ID=34967690
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210551546.7A Active CN103157294B (zh) | 2004-05-21 | 2005-05-14 | 利用集成多柱色谱制备化学品和药品的方法 |
CN2005800246655A Active CN101321567B (zh) | 2004-05-21 | 2005-05-14 | 利用集成多柱色谱制备化学品和药品的方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210551546.7A Active CN103157294B (zh) | 2004-05-21 | 2005-05-14 | 利用集成多柱色谱制备化学品和药品的方法 |
Country Status (11)
Country | Link |
---|---|
US (2) | US7615159B2 (zh) |
EP (2) | EP2336617B1 (zh) |
JP (3) | JP5021466B2 (zh) |
CN (2) | CN103157294B (zh) |
BR (1) | BRPI0510143B1 (zh) |
DE (1) | DE102004025000A1 (zh) |
HK (1) | HK1127311A1 (zh) |
IL (1) | IL179451A (zh) |
MX (1) | MXPA06013419A (zh) |
NO (1) | NO340260B1 (zh) |
WO (1) | WO2005113101A2 (zh) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103331036A (zh) * | 2013-06-21 | 2013-10-02 | 浙江大学宁波理工学院 | 一种从混合物中分离与富集目标组分的色谱分离方法 |
CN104415573A (zh) * | 2013-09-10 | 2015-03-18 | 中国科学院大连化学物理研究所 | 一种延胡索提取物中叔胺碱和季铵碱的分类制备方法 |
CN107185273A (zh) * | 2017-06-15 | 2017-09-22 | 苏州麦可旺志生物技术有限公司 | 一种连续色谱的方法及其设备 |
CN111841073A (zh) * | 2019-09-12 | 2020-10-30 | 浙江大学宁波理工学院 | 从原料中分离与浓缩目标组分的多柱切换循环色谱分离***及其方法 |
US11484822B2 (en) | 2016-01-27 | 2022-11-01 | Koch-Giltsch, LP | Inlet vane device and vessel containing same |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2889077B1 (fr) * | 2005-07-26 | 2007-10-12 | Novasep Soc Par Actions Simpli | Procede et dispositif de separation chromatographique de fractions d'un melange |
DE502007004854D1 (de) * | 2007-04-17 | 2010-10-07 | Max Planck Gesellschaft | Verfahren und Vorrichtung zur chromatographischen Trennung von Komponenten mit teilweiser Rückführung von Gemischfraktionen |
FR2976500B1 (fr) * | 2011-06-16 | 2013-05-31 | IFP Energies Nouvelles | Procede et dispositif de sepation chromatographique a contre-courant simule a faible perte de charge et nombre de zones eleve. |
DE102017107089B4 (de) * | 2017-04-03 | 2019-08-22 | Karlsruher Institut für Technologie | Vorrichtung und Verfahren zur selektiven Fraktionierung von Feinstpartikeln |
EP3801810A1 (en) * | 2018-05-31 | 2021-04-14 | Waters Technologies Corporation | High resolution and semi-preparative recycling chromatography system for isolation and preparation of unknown trace impurities in pharmaceutical products |
US11346460B2 (en) | 2019-02-05 | 2022-05-31 | Swagelok Company | Integrated actuator manifold for multiple valve assembly |
WO2020194343A1 (en) * | 2019-03-22 | 2020-10-01 | Indian Institute Of Technology Delhi | An nir based real-time control of loading in protein a chromatography |
Family Cites Families (42)
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US3268605A (en) | 1961-11-06 | 1966-08-23 | Universal Oil Prod Co | Supervisory control system for a simulated moving bed separation process |
US3706612A (en) | 1968-07-16 | 1972-12-19 | Ibm | Process for etching silicon nitride |
JPS54156223A (en) * | 1978-05-31 | 1979-12-10 | Maenakaseisakushiyo Kk | Starter valve |
US4499115A (en) | 1980-01-07 | 1985-02-12 | Unisearch Limited | Antioxidant benzodioxole compound |
JPS56153164A (en) * | 1981-03-23 | 1981-11-27 | Keiji Inouchi | Pressure reducing flow control valve |
US4434051A (en) | 1982-06-07 | 1984-02-28 | Uop Inc. | Multiple valve apparatus for simulated moving bed adsorption processes |
US4447329A (en) * | 1983-06-13 | 1984-05-08 | Uop Inc. | Continuous desalination process |
EP0146810A3 (de) * | 1983-12-05 | 1987-05-13 | Solco Basel AG | Verfahren zur Herstellung von Sphingosinderivaten |
US4659722A (en) * | 1984-08-20 | 1987-04-21 | Nippon Kayaku Kabushiki Kaisha | Bactericidal N-(2,2,2 trichloroethyl)pyridinecarboxamides |
US5110987A (en) * | 1988-06-17 | 1992-05-05 | Emory University | Method of preparing sphingosine derivatives |
ZA902794B (en) * | 1989-04-18 | 1991-04-24 | Duphar Int Res | New 3-n substituted carbamoyl-indole derivatives |
EP0427671B1 (de) * | 1989-11-08 | 1994-07-27 | Ciba-Geigy Ag | Ventil |
JP2925753B2 (ja) | 1990-02-23 | 1999-07-28 | ダイセル化学工業株式会社 | 光学異性体の分離方法 |
EP0586385B2 (de) | 1991-03-14 | 2005-03-30 | Bayer Ag | Verfahren zur trennung von enantiomeren an chiralen trennphasen mit hilfe eines kontinuierlichen gegenstrom-chromatographieverfahrens |
JP3010816B2 (ja) | 1991-08-22 | 2000-02-21 | ダイセル化学工業株式会社 | 光学分割における光学異性体と溶媒との回収方法、溶媒の循環使用方法、および光学異性体の再利用方法 |
US5294722A (en) * | 1992-04-16 | 1994-03-15 | E. R. Squibb & Sons, Inc. | Process for the preparation of imidazoles useful in angiotensin II antagonism |
US5403851A (en) * | 1994-04-05 | 1995-04-04 | Interneuron Pharmaceuticals, Inc. | Substituted tryptamines, phenalkylamines and related compounds |
US5470464A (en) * | 1994-04-06 | 1995-11-28 | Uop | Small scale simulated moving bed separation apparatus and process |
FR2719233B1 (fr) | 1994-04-28 | 1996-07-19 | Inst Francais Du Petrole | Procédé de séparation en lit mobile simulé à débit de recyclage constant. |
FR2721527B1 (fr) | 1994-06-22 | 1996-09-06 | Inst Francais Du Petrole | Procédé de séparation par chromatographie en lit mobile simulé avec correction de volume mort par augmentation de débit. |
FR2721528B1 (fr) | 1994-06-22 | 1996-09-06 | Inst Francais Du Petrole | Procédé de séparation par chromatographie en lit mobile simulé avec correction de volume mort par desynchronisation des périodes. |
FR2721529B1 (fr) | 1994-06-22 | 1996-09-06 | Inst Francais Du Petrole | Procédé de séparation par chromatographie en lit mobile simulé avec correction de volume mort par diminution de longueur. |
DE4421934A1 (de) | 1994-06-23 | 1996-01-04 | Ford Werke Ag | Metallisches Profil als Verstärkung einer Kraftfahrzeugtür |
JPH09206502A (ja) * | 1995-12-01 | 1997-08-12 | Daicel Chem Ind Ltd | 擬似移動床式分離装置 |
US5635072A (en) * | 1995-01-31 | 1997-06-03 | Uop | Simulated moving bed adsorptive separation process |
JP3258513B2 (ja) * | 1995-02-28 | 2002-02-18 | オルガノ株式会社 | 擬似移動層式クロマト分離操作を用いる有用物質の製造方法 |
FR2743002B1 (fr) | 1995-12-27 | 1998-01-30 | Inst Francais Du Petrole | Procede de regulation d'au moins un debit de fluide circulant dans une boucle de separation chromatographique en lit mobile simule |
KR100559817B1 (ko) * | 1997-03-12 | 2006-03-10 | 다카라 바이오 가부시키가이샤 | 스핑고신 유사화합물 |
FR2766385B1 (fr) | 1997-07-24 | 1999-09-03 | Novasep | Procede pour le controle de la pression dans un systeme de separation a lit mobile simule |
US6239297B1 (en) * | 1997-09-11 | 2001-05-29 | Takara Shuzo Co., Ltd. | Sphingosine derivatives and medicinal composition |
JPH11153231A (ja) * | 1997-11-20 | 1999-06-08 | Sony Corp | 薬液供給バルブおよび薬液供給装置 |
JPH11228455A (ja) * | 1998-02-18 | 1999-08-24 | Japan Organo Co Ltd | 有用物質の製造方法 |
FR2779067B1 (fr) | 1998-05-29 | 2000-08-18 | Inst Francais Du Petrole | Dispositif de regulation de debit d'au moins un fluide d'unites de separation par lit mobile simule |
FR2785196B1 (fr) | 1998-10-29 | 2000-12-15 | Inst Francais Du Petrole | Procede et dispositif de separation avec des zones chromatographiques a longueur variable |
JP4176240B2 (ja) * | 1999-07-02 | 2008-11-05 | オルガノ株式会社 | クロマト分離装置 |
US6386508B1 (en) * | 2000-06-05 | 2002-05-14 | D-M-E Company | Actuator having dual piston surfaces |
CN2484564Y (zh) * | 2001-06-06 | 2002-04-03 | 浙江大学 | 开环结构的模拟移动床色谱装置 |
ATE367812T1 (de) * | 2001-06-20 | 2007-08-15 | Wyeth Corp | Substituierte indolsäurederivate als inhibitoren von plasminogen-aktivator-inhibitor-1 (pai-1) |
DE10161388A1 (de) * | 2001-12-14 | 2003-07-03 | Bayer Ag | Ventil |
CN1169595C (zh) * | 2002-03-13 | 2004-10-06 | 浙江大学 | 模拟移动床色谱反应器 |
JP2004077329A (ja) * | 2002-08-20 | 2004-03-11 | Japan Organo Co Ltd | クロマト分離装置 |
US7544293B2 (en) * | 2005-09-26 | 2009-06-09 | Semba Inc. | Valve and process for interrupted continuous flow chromatography |
-
2004
- 2004-05-21 DE DE200410025000 patent/DE102004025000A1/de not_active Withdrawn
-
2005
- 2005-05-14 CN CN201210551546.7A patent/CN103157294B/zh active Active
- 2005-05-14 CN CN2005800246655A patent/CN101321567B/zh active Active
- 2005-05-14 EP EP11155542.1A patent/EP2336617B1/de active Active
- 2005-05-14 JP JP2007517065A patent/JP5021466B2/ja active Active
- 2005-05-14 BR BRPI0510143-3A patent/BRPI0510143B1/pt not_active IP Right Cessation
- 2005-05-14 MX MXPA06013419A patent/MXPA06013419A/es active IP Right Grant
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103331036A (zh) * | 2013-06-21 | 2013-10-02 | 浙江大学宁波理工学院 | 一种从混合物中分离与富集目标组分的色谱分离方法 |
CN104415573A (zh) * | 2013-09-10 | 2015-03-18 | 中国科学院大连化学物理研究所 | 一种延胡索提取物中叔胺碱和季铵碱的分类制备方法 |
CN104415573B (zh) * | 2013-09-10 | 2017-03-22 | 中国科学院大连化学物理研究所 | 一种延胡索提取物中叔胺碱和季铵碱的分类制备方法 |
US11484822B2 (en) | 2016-01-27 | 2022-11-01 | Koch-Giltsch, LP | Inlet vane device and vessel containing same |
CN107185273A (zh) * | 2017-06-15 | 2017-09-22 | 苏州麦可旺志生物技术有限公司 | 一种连续色谱的方法及其设备 |
CN111841073A (zh) * | 2019-09-12 | 2020-10-30 | 浙江大学宁波理工学院 | 从原料中分离与浓缩目标组分的多柱切换循环色谱分离***及其方法 |
CN111841073B (zh) * | 2019-09-12 | 2022-02-22 | 浙江大学宁波理工学院 | 从原料中分离与浓缩目标组分的多柱切换循环色谱分离***及其方法 |
Also Published As
Publication number | Publication date |
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US20090294364A1 (en) | 2009-12-03 |
HK1127311A1 (en) | 2009-09-25 |
EP1753517A2 (de) | 2007-02-21 |
JP2008500544A (ja) | 2008-01-10 |
DE102004025000A1 (de) | 2005-12-08 |
BRPI0510143A (pt) | 2007-10-02 |
EP2336617A3 (de) | 2012-09-12 |
BRPI0510143B1 (pt) | 2017-12-19 |
JP2012115832A (ja) | 2012-06-21 |
WO2005113101A2 (de) | 2005-12-01 |
IL179451A0 (en) | 2007-05-15 |
NO340260B1 (no) | 2017-03-27 |
EP2336617B1 (de) | 2014-02-26 |
CN103157294B (zh) | 2015-07-29 |
JP5122679B2 (ja) | 2013-01-16 |
WO2005113101A8 (de) | 2008-07-17 |
JP2011174941A (ja) | 2011-09-08 |
JP5122667B2 (ja) | 2013-01-16 |
CN101321567B (zh) | 2013-03-06 |
NO20065865L (no) | 2007-02-21 |
EP1753517B1 (de) | 2013-07-10 |
WO2005113101A3 (de) | 2008-04-17 |
MXPA06013419A (es) | 2007-01-23 |
EP2336617A2 (de) | 2011-06-22 |
US20080135483A1 (en) | 2008-06-12 |
IL179451A (en) | 2011-07-31 |
JP5021466B2 (ja) | 2012-09-05 |
US8658040B2 (en) | 2014-02-25 |
CN103157294A (zh) | 2013-06-19 |
US7615159B2 (en) | 2009-11-10 |
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