CL2019000462A1 - Compuestos derivados de indol, composiciones que los contienen, útiles en el tratamiento de infestación por helmintos, preferentemente trematodos, en mamíferos. (divisional solicitud 201603258) - Google Patents
Compuestos derivados de indol, composiciones que los contienen, útiles en el tratamiento de infestación por helmintos, preferentemente trematodos, en mamíferos. (divisional solicitud 201603258)Info
- Publication number
- CL2019000462A1 CL2019000462A1 CL2019000462A CL2019000462A CL2019000462A1 CL 2019000462 A1 CL2019000462 A1 CL 2019000462A1 CL 2019000462 A CL2019000462 A CL 2019000462A CL 2019000462 A CL2019000462 A CL 2019000462A CL 2019000462 A1 CL2019000462 A1 CL 2019000462A1
- Authority
- CL
- Chile
- Prior art keywords
- useful
- trematodes
- indole
- mammals
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03K—PULSE TECHNIQUE
- H03K5/00—Manipulating of pulses not covered by one of the other main groups of this subclass
- H03K5/01—Shaping pulses
- H03K5/04—Shaping pulses by increasing duration; by decreasing duration
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03K—PULSE TECHNIQUE
- H03K7/00—Modulating pulses with a continuously-variable modulating signal
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nonlinear Science (AREA)
- Physics & Mathematics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
COMPUESTO DE FÓRMULA (I) EN DONDE R1 ES CF3; R2 ES H; R3 ES FENILO O HETEROARILO; EN DONDE EL FENILO O HETEROARILO ES NO SUSTITUIDO O SUSTITUIDO CON UNO O MÁS DE HALÓGENO, (C1-C3)-HALOALQUILO O CIANO; R4 ES H O HALÓGENO; R5 ES H; Y R6 ES H; O UNA SAL FARMACÉUTICAMENTE ACEPTABLE DEL MISMO; COMPOSICIÓN QUE COMPRENDE UNA CANTIDAD ANTIHELMÍNTICAMENTE EFECTIVA DE DICHO COMPUESTO Y UN PORTADOR FARMACÉUTICAMENTE ACEPTABLE; USO DE DICHO COMPUESTO PARA PREPARAR UN MEDICAMENTO ÚTIL PARA TRATAR UNA INFESTACIÓN DE HELMINTOS EN UN ANIMAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462014245P | 2014-06-19 | 2014-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2019000462A1 true CL2019000462A1 (es) | 2019-05-10 |
Family
ID=54868421
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2016003258A CL2016003258A1 (es) | 2014-06-19 | 2016-12-19 | Composiciones parasiticidas que comprenden derivados de indol, métodos y usos de las mismas. |
CL2019000462A CL2019000462A1 (es) | 2014-06-19 | 2019-02-21 | Compuestos derivados de indol, composiciones que los contienen, útiles en el tratamiento de infestación por helmintos, preferentemente trematodos, en mamíferos. (divisional solicitud 201603258) |
CL2020002588A CL2020002588A1 (es) | 2014-06-19 | 2020-10-07 | Compuestos derivados de indol, composiciones que los contienen, útiles en el tratamiento de infestación por helmintos, preferentemente trematodos, en mamíferos. (divisional de solicitud n° 03258-2016) |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2016003258A CL2016003258A1 (es) | 2014-06-19 | 2016-12-19 | Composiciones parasiticidas que comprenden derivados de indol, métodos y usos de las mismas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2020002588A CL2020002588A1 (es) | 2014-06-19 | 2020-10-07 | Compuestos derivados de indol, composiciones que los contienen, útiles en el tratamiento de infestación por helmintos, preferentemente trematodos, en mamíferos. (divisional de solicitud n° 03258-2016) |
Country Status (15)
Country | Link |
---|---|
US (2) | US9776986B2 (es) |
EP (2) | EP3157912B1 (es) |
JP (1) | JP6619756B2 (es) |
CN (1) | CN106536481B (es) |
AU (2) | AU2015276941B2 (es) |
BR (2) | BR122020023385B1 (es) |
CA (1) | CA2952857A1 (es) |
CL (3) | CL2016003258A1 (es) |
CO (1) | CO2017000412A2 (es) |
EA (1) | EA030459B1 (es) |
ES (2) | ES2723969T3 (es) |
MX (2) | MX2016016928A (es) |
NZ (1) | NZ728102A (es) |
PT (1) | PT3157912T (es) |
WO (1) | WO2015196014A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3307706B1 (en) * | 2015-06-15 | 2019-07-24 | Bayer CropScience AG | Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides |
CN107082758A (zh) * | 2016-02-15 | 2017-08-22 | 中山大学 | 一种合成吲哚衍生物的方法 |
US10426772B2 (en) | 2016-05-16 | 2019-10-01 | Regents Of The University Of Minnesota | Use of ergot alkaloids as an anthelmintic agent |
KR102204380B1 (ko) * | 2019-04-03 | 2021-01-19 | 영남대학교산학협력단 | 5-브로모인돌을 유효성분으로 함유하는 소나무재선충병 방제용 조성물 및 이의 용도 |
CN112675850A (zh) * | 2020-12-23 | 2021-04-20 | 江苏广域化学有限公司 | 镍催化剂、其制备方法及嘧啶类衍生物的合成方法 |
CN113109332A (zh) * | 2021-04-14 | 2021-07-13 | 山东商业职业技术学院 | 食盐中碘酸钾的快速检测试剂及方法 |
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WO2012088431A1 (en) * | 2010-12-23 | 2012-06-28 | Ironwood Pharmaceuticals, Inc. | Faah inhibitors |
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2015
- 2015-06-19 EA EA201790040A patent/EA030459B1/ru unknown
- 2015-06-19 EP EP15738519.6A patent/EP3157912B1/en active Active
- 2015-06-19 ES ES15738519T patent/ES2723969T3/es active Active
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- 2015-06-19 PT PT15738519T patent/PT3157912T/pt unknown
- 2015-06-19 CA CA2952857A patent/CA2952857A1/en not_active Abandoned
- 2015-06-19 BR BR122020023385-0A patent/BR122020023385B1/pt not_active IP Right Cessation
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- 2015-06-19 ES ES18212461T patent/ES2895826T3/es active Active
- 2015-06-19 JP JP2016574080A patent/JP6619756B2/ja not_active Expired - Fee Related
- 2015-06-19 NZ NZ728102A patent/NZ728102A/en unknown
- 2015-06-19 US US14/744,166 patent/US9776986B2/en active Active
- 2015-06-19 MX MX2016016928A patent/MX2016016928A/es active IP Right Grant
- 2015-06-19 AU AU2015276941A patent/AU2015276941B2/en active Active
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2018
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NZ728102A (en) | 2018-04-27 |
MX2019012952A (es) | 2019-12-16 |
JP6619756B2 (ja) | 2019-12-11 |
US20170290803A1 (en) | 2017-10-12 |
CL2016003258A1 (es) | 2017-06-16 |
CA2952857A1 (en) | 2015-12-23 |
WO2015196014A1 (en) | 2015-12-23 |
CN106536481B (zh) | 2019-11-22 |
EP3517524A1 (en) | 2019-07-31 |
MX2016016928A (es) | 2017-04-25 |
JP2017518352A (ja) | 2017-07-06 |
ES2723969T3 (es) | 2019-09-04 |
AU2018205140A1 (en) | 2018-08-02 |
BR112016029888B1 (pt) | 2021-05-18 |
US20150366198A1 (en) | 2015-12-24 |
EP3157912A1 (en) | 2017-04-26 |
CN106536481A (zh) | 2017-03-22 |
EA201790040A1 (ru) | 2017-05-31 |
EA030459B1 (ru) | 2018-08-31 |
US10251863B2 (en) | 2019-04-09 |
US9776986B2 (en) | 2017-10-03 |
AU2015276941A1 (en) | 2017-02-02 |
CL2020002588A1 (es) | 2021-01-22 |
AU2015276941B2 (en) | 2018-07-19 |
ES2895826T3 (es) | 2022-02-22 |
BR112016029888A2 (pt) | 2017-08-22 |
CO2017000412A2 (es) | 2017-04-28 |
EP3157912B1 (en) | 2019-02-20 |
PT3157912T (pt) | 2019-06-04 |
BR122020023385B1 (pt) | 2021-05-25 |
EP3517524B1 (en) | 2021-05-26 |
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