CL2017003456A1 - Metodos para tratar tumores de celulas epitelioides - Google Patents
Metodos para tratar tumores de celulas epitelioidesInfo
- Publication number
- CL2017003456A1 CL2017003456A1 CL2017003456A CL2017003456A CL2017003456A1 CL 2017003456 A1 CL2017003456 A1 CL 2017003456A1 CL 2017003456 A CL2017003456 A CL 2017003456A CL 2017003456 A CL2017003456 A CL 2017003456A CL 2017003456 A1 CL2017003456 A1 CL 2017003456A1
- Authority
- CL
- Chile
- Prior art keywords
- treat
- methods
- cell tumors
- epithelioid cell
- epithelioid
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 210000003237 epithelioid cell Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 229940124302 mTOR inhibitor Drugs 0.000 abstract 1
- 239000003628 mammalian target of rapamycin inhibitor Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
<p> </p> <p>LA PRESENTE INVENCIÓN PROPORCIONA MÉTODOS Y COMPOSICIONES PARA TRATAR TUMORES DE CÉLULAS EPITELIOIDES (COMO PECOMA) MEDIANTE LA ADMINISTRACIÓN DE UNA COMPOSICIÓN QUE COMPRENDE NANOPARTÍCULAS QUE COMPRENDEN UN INHIBIDOR MTOR Y UNA ALBÚMINA.</p>
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562186252P | 2015-06-29 | 2015-06-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2017003456A1 true CL2017003456A1 (es) | 2018-05-11 |
Family
ID=57609139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2017003456A CL2017003456A1 (es) | 2015-06-29 | 2017-12-28 | Metodos para tratar tumores de celulas epitelioides |
Country Status (26)
Country | Link |
---|---|
US (2) | US10973806B2 (es) |
EP (2) | EP3998069A1 (es) |
JP (3) | JP6987644B2 (es) |
KR (2) | KR102606071B1 (es) |
CN (3) | CN108024999A (es) |
AU (2) | AU2016285720C1 (es) |
BR (1) | BR112017027954B1 (es) |
CA (1) | CA2990693C (es) |
CL (1) | CL2017003456A1 (es) |
CY (1) | CY1124926T1 (es) |
DK (1) | DK3313401T3 (es) |
EA (2) | EA202092187A1 (es) |
ES (1) | ES2897991T3 (es) |
HK (1) | HK1247094A1 (es) |
HR (1) | HRP20211718T1 (es) |
HU (1) | HUE057175T2 (es) |
IL (1) | IL256274B2 (es) |
LT (1) | LT3313401T (es) |
MX (2) | MX2017016322A (es) |
PL (1) | PL3313401T3 (es) |
PT (1) | PT3313401T (es) |
RS (1) | RS62743B1 (es) |
SG (1) | SG10202107198SA (es) |
SI (1) | SI3313401T1 (es) |
WO (1) | WO2017004249A1 (es) |
ZA (1) | ZA201708567B (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10973806B2 (en) | 2015-06-29 | 2021-04-13 | Abraxis Bioscience, Llc | Methods of treating epithelioid cell tumors comprising administering a composition comprising nanoparticles comprising an mTOR inhibitor and an albumin |
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EP2552439B1 (en) | 2010-03-29 | 2022-07-20 | Abraxis BioScience, LLC | Methods of enhancing drug delivery and effectiveness of therapeutic agents |
CN103648521A (zh) | 2011-04-28 | 2014-03-19 | 阿布拉科斯生物科学有限公司 | 纳米颗粒组合物的血管内递送及其应用 |
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US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
EP3698784A1 (en) | 2013-03-12 | 2020-08-26 | Abraxis BioScience, LLC | Methods of treating lung cancer |
CA2903548A1 (en) | 2013-03-14 | 2014-09-25 | Abraxis Bioscience, Llc | Methods of treating bladder cancer |
US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
EP3768268A4 (en) | 2018-03-20 | 2022-02-23 | Abraxis BioScience, LLC | METHOD OF TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS BY ADMINISTRATION OF NANOPARTICLES OF AN MTOR INHIBITOR AND AN ALBUMINE |
SG11202011462SA (en) * | 2018-05-22 | 2020-12-30 | Abraxis Bioscience Llc | Methods and compositions for treating pulmonary hypertension |
CN109182519B (zh) * | 2018-09-17 | 2019-06-14 | 中国人民解放军***南京总医院 | 一种用于诊断acta2-mitf易位性血管周上皮样细胞肿瘤的探针组合及其应用 |
CN113795287A (zh) * | 2019-03-19 | 2021-12-14 | 阿布拉科斯生物科学有限公司 | 皮下施用包含mTOR抑制剂和白蛋白的纳米颗粒以治疗疾病 |
AU2020375810A1 (en) * | 2019-10-28 | 2022-05-12 | Abraxis Bioscience, Llc | Pharmaceutical compositions of albumin and rapamycin |
KR20220113699A (ko) * | 2019-11-11 | 2022-08-16 | 아브락시스 바이오사이언스, 엘엘씨 | 나노입자 조성물에 대한 바이오마커 |
TW202123935A (zh) * | 2019-11-11 | 2021-07-01 | 美商亞伯辛生物科學有限責任公司 | 用於奈米粒子組合物之生物標記 |
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RS62743B1 (sr) | 2015-06-29 | 2022-01-31 | Abraxis Bioscience Llc | Nanočestice koje sadrže sirolimus i albumin za primenu u lečenju tumora epiteloidnih ćelija |
IL256326B1 (en) | 2015-06-29 | 2024-05-01 | Abraxis Bioscience Llc | Biomarkers for nanoparticle preparations |
US20180153863A1 (en) | 2015-06-29 | 2018-06-07 | Abraxis Bioscience, Llc | Methods of treating solid tumors using nanoparticle mtor inhibitor combination therapy |
US20170181988A1 (en) | 2015-12-23 | 2017-06-29 | Cipla Limited | Methods for the treatment of bladder cancer |
US20190147986A1 (en) | 2016-05-17 | 2019-05-16 | Abraxis Bioscience, Llc | Methods for assessing neoadjuvant therapies |
MA46365A (fr) | 2016-09-28 | 2019-08-07 | Abraxis Bioscience Llc | Méthodes de traitement de troubles mitochondriaux et métaboliques |
JP2019529520A (ja) | 2016-10-07 | 2019-10-17 | アブラクシス バイオサイエンス, エルエルシー | 胆道がんを処置する方法 |
WO2018071399A1 (en) | 2016-10-10 | 2018-04-19 | Abraxis Bioscience, Llc | Nanoparticle formulations and methods of making and using thereof |
US20180374583A1 (en) | 2017-05-16 | 2018-12-27 | Abraxis Bioscience, Llc | Nomogram and survival predictions for pancreatic cancer |
EP3727368A4 (en) | 2017-12-19 | 2021-10-20 | Abraxis BioScience, LLC | METHOD OF TREATMENT IN COLON CANCER WITH NANOPARTICLE MTOR INHIBITOR COMBINATION THERAPY |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10973806B2 (en) | 2015-06-29 | 2021-04-13 | Abraxis Bioscience, Llc | Methods of treating epithelioid cell tumors comprising administering a composition comprising nanoparticles comprising an mTOR inhibitor and an albumin |
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