CL2015002301A1 - Acido 2-aza-biciclo[2.2.1]heptano-3-carboxílico (bencil-ciano-metil)-amidas sustituidas inhibidores de catepsina c. - Google Patents
Acido 2-aza-biciclo[2.2.1]heptano-3-carboxílico (bencil-ciano-metil)-amidas sustituidas inhibidores de catepsina c.Info
- Publication number
- CL2015002301A1 CL2015002301A1 CL2015002301A CL2015002301A CL2015002301A1 CL 2015002301 A1 CL2015002301 A1 CL 2015002301A1 CL 2015002301 A CL2015002301 A CL 2015002301A CL 2015002301 A CL2015002301 A CL 2015002301A CL 2015002301 A1 CL2015002301 A1 CL 2015002301A1
- Authority
- CL
- Chile
- Prior art keywords
- aza
- bicyclo
- heptane
- cyano
- benzyl
- Prior art date
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
COMPUESTOS DERIVADOS DE ACIDO 2-AZA-BICICLO[2.2.1]HEPTANO-3-CARBOXÍLICO (BENCIL-CIANO-METIL)-AMIDAS SUSTITUIDAS, COMO INHIBIDORES DE CATEPSINA C; COMPOSICION FARMACEUTICA QUE LOS COMPRENDE; Y SU USO PARA EL TRATAMIENTO DE ASMA Y ENFERMEDADES ALERGICAS, ENFERMEDADES INFLAMATORIAS GASTROINTESTINALES, ENFERMEDADES EOSINOFILICAS, EPOC, INFECCION POR MICROBIOS PATOGENOS, ARTRITIS REUMATOIDE Y LA ATEROSCLEROSIS.
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