CL2013001831A1 - Proteina de enlace multivalente y multiespecifica que une a il-1 alfa y beta; conjugado que la comprende; acido nucleico que la codifica; vector; celula huesped; metodo de produccion; composicion farmaceutica que la comprende; y sus usos. - Google Patents
Proteina de enlace multivalente y multiespecifica que une a il-1 alfa y beta; conjugado que la comprende; acido nucleico que la codifica; vector; celula huesped; metodo de produccion; composicion farmaceutica que la comprende; y sus usos.Info
- Publication number
- CL2013001831A1 CL2013001831A1 CL2013001831A CL2013001831A CL2013001831A1 CL 2013001831 A1 CL2013001831 A1 CL 2013001831A1 CL 2013001831 A CL2013001831 A CL 2013001831A CL 2013001831 A CL2013001831 A CL 2013001831A CL 2013001831 A1 CL2013001831 A1 CL 2013001831A1
- Authority
- CL
- Chile
- Prior art keywords
- multivalent
- conjugate
- binds
- beta
- alpha
- Prior art date
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- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- A61K2039/507—Comprising a combination of two or more separate antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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2011
- 2011-12-20 RU RU2013133811A patent/RU2627171C2/ru active
- 2011-12-20 MY MYPI2013701024A patent/MY163368A/en unknown
- 2011-12-20 CA CA2821976A patent/CA2821976A1/en not_active Abandoned
- 2011-12-20 SG SG2013048483A patent/SG191312A1/en unknown
- 2011-12-20 AU AU2011361720A patent/AU2011361720B2/en active Active
- 2011-12-20 KR KR1020137018960A patent/KR20130133247A/ko active Search and Examination
- 2011-12-20 TW TW100147523A patent/TW201249865A/zh unknown
- 2011-12-20 JP JP2013546325A patent/JP6009455B2/ja not_active Expired - Fee Related
- 2011-12-20 SG SG10201604699VA patent/SG10201604699VA/en unknown
- 2011-12-20 CN CN201180066566.9A patent/CN103517921B/zh active Active
- 2011-12-20 EP EP11820904.8A patent/EP2655417A2/en not_active Withdrawn
- 2011-12-20 US US13/331,422 patent/US8853365B2/en active Active
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- 2011-12-20 BR BR112013015944A patent/BR112013015944A2/pt not_active IP Right Cessation
- 2011-12-20 WO PCT/US2011/066130 patent/WO2012121775A2/en active Application Filing
- 2011-12-20 PE PE2013001458A patent/PE20141060A1/es not_active Application Discontinuation
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2013
- 2013-06-20 GT GT201300160A patent/GT201300160A/es unknown
- 2013-06-20 CL CL2013001831A patent/CL2013001831A1/es unknown
- 2013-06-20 DO DO2013000145A patent/DOP2013000145A/es unknown
- 2013-06-28 CO CO13154195A patent/CO6771416A2/es unknown
- 2013-07-10 CR CR20130340A patent/CR20130340A/es unknown
- 2013-07-17 EC ECSP13012776 patent/ECSP13012776A/es unknown
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2014
- 2014-08-22 US US14/466,060 patent/US20150093387A1/en not_active Abandoned
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Also Published As
Publication number | Publication date |
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JP2014504860A (ja) | 2014-02-27 |
TW201249865A (en) | 2012-12-16 |
JP2017029157A (ja) | 2017-02-09 |
GT201300160A (es) | 2014-08-05 |
US8853365B2 (en) | 2014-10-07 |
KR20130133247A (ko) | 2013-12-06 |
JP6009455B2 (ja) | 2016-10-19 |
RU2013133811A (ru) | 2015-01-27 |
PE20141060A1 (es) | 2014-09-26 |
MY163368A (en) | 2017-09-15 |
CN103517921B (zh) | 2017-07-18 |
WO2012121775A9 (en) | 2013-01-17 |
DOP2013000145A (es) | 2013-11-15 |
EP2655417A2 (en) | 2013-10-30 |
CA2821976A1 (en) | 2012-09-13 |
WO2012121775A3 (en) | 2012-11-01 |
WO2012121775A2 (en) | 2012-09-13 |
SG10201604699VA (en) | 2016-07-28 |
AU2011361720A1 (en) | 2013-07-04 |
US20150093387A1 (en) | 2015-04-02 |
ECSP13012776A (es) | 2013-09-30 |
SG191312A1 (en) | 2013-07-31 |
US20120189541A1 (en) | 2012-07-26 |
BR112013015944A2 (pt) | 2018-06-19 |
AU2011361720B2 (en) | 2017-04-27 |
CO6771416A2 (es) | 2013-10-15 |
MX2013007332A (es) | 2014-01-23 |
CN103517921A (zh) | 2014-01-15 |
RU2627171C2 (ru) | 2017-08-03 |
CR20130340A (es) | 2013-10-15 |
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