CL2008003120A1 - Compuestos derivados de fenilalquil-, fenilalquenil-, fenilalquinil- amina, feniltioalquilamina, fenilaminoalquilamina, fenilalcoxiamina y fenilalquilguanidina; composicion farmaceutica; y uso de los compuestos para tratar un trastorno o enfermedad oftalmologica tal como retinopatia, maculopatia, retinitis pigmentosa, uveitis, entre otras. - Google Patents
Compuestos derivados de fenilalquil-, fenilalquenil-, fenilalquinil- amina, feniltioalquilamina, fenilaminoalquilamina, fenilalcoxiamina y fenilalquilguanidina; composicion farmaceutica; y uso de los compuestos para tratar un trastorno o enfermedad oftalmologica tal como retinopatia, maculopatia, retinitis pigmentosa, uveitis, entre otras.Info
- Publication number
- CL2008003120A1 CL2008003120A1 CL2008003120A CL2008003120A CL2008003120A1 CL 2008003120 A1 CL2008003120 A1 CL 2008003120A1 CL 2008003120 A CL2008003120 A CL 2008003120A CL 2008003120 A CL2008003120 A CL 2008003120A CL 2008003120 A1 CL2008003120 A1 CL 2008003120A1
- Authority
- CL
- Chile
- Prior art keywords
- compounds
- disease
- pharmaceutical composition
- amine
- phenylthioalkylamine
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 150000001412 amines Chemical class 0.000 title abstract 2
- 208000002780 macular degeneration Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000035719 Maculopathy Diseases 0.000 title 1
- 208000017442 Retinal disease Diseases 0.000 title 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 title 1
- 206010038923 Retinopathy Diseases 0.000 title 1
- 206010046851 Uveitis Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 125000003884 phenylalkyl group Chemical group 0.000 title 1
- 208000027073 Stargardt disease Diseases 0.000 abstract 1
- 206010064930 age-related macular degeneration Diseases 0.000 abstract 1
- 208000030533 eye disease Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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Abstract
Compuestos derivados de amina, composición farmacéutica, y uso en el tratamiento de enfermedades y/o desórdenes oculares, tales como, degeneración macular asociada al envejecimiento y Enfermedad de Stargardt.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98466707P | 2007-11-01 | 2007-11-01 |
Publications (1)
Publication Number | Publication Date |
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CL2008003120A1 true CL2008003120A1 (es) | 2009-10-09 |
Family
ID=40097866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003120A CL2008003120A1 (es) | 2007-11-01 | 2008-10-22 | Compuestos derivados de fenilalquil-, fenilalquenil-, fenilalquinil- amina, feniltioalquilamina, fenilaminoalquilamina, fenilalcoxiamina y fenilalquilguanidina; composicion farmaceutica; y uso de los compuestos para tratar un trastorno o enfermedad oftalmologica tal como retinopatia, maculopatia, retinitis pigmentosa, uveitis, entre otras. |
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US (5) | US8076516B2 (es) |
EP (1) | EP2111223A4 (es) |
JP (3) | JP5592265B2 (es) |
KR (2) | KR101270122B1 (es) |
CN (1) | CN101917980B (es) |
AR (1) | AR070950A1 (es) |
AU (1) | AU2008319397B2 (es) |
BR (1) | BRPI0819241A2 (es) |
CA (1) | CA2704199C (es) |
CL (1) | CL2008003120A1 (es) |
CO (1) | CO6501155A2 (es) |
EC (1) | ECSP10010226A (es) |
GB (1) | GB2455176A (es) |
HK (1) | HK1151736A1 (es) |
IL (1) | IL205112A0 (es) |
MX (1) | MX2010004718A (es) |
MY (2) | MY156662A (es) |
PH (2) | PH12015501208A1 (es) |
RU (1) | RU2536040C2 (es) |
SG (1) | SG185939A1 (es) |
TW (1) | TWI446904B (es) |
WO (1) | WO2009058216A1 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8299307B2 (en) * | 2007-06-29 | 2012-10-30 | Acucela Inc. | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders |
JP5592265B2 (ja) * | 2007-11-01 | 2014-09-17 | アキュセラ インコーポレイテッド | 眼の疾患及び障害治療用のアミン誘導体化合物 |
CN102203058B (zh) * | 2008-09-05 | 2014-11-12 | 奥克塞拉有限公司 | 用于治疗眼科疾病和紊乱的连接有硫的化合物 |
IN2012DN00352A (es) * | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
KR101669705B1 (ko) * | 2009-09-09 | 2016-10-27 | 미츠비시 가스 가가쿠 가부시키가이샤 | 환상 화합물, 그 제조 방법, 감방사선성 조성물 및 레지스트 패턴 형성 방법 |
CN103347517B (zh) | 2010-08-11 | 2018-10-02 | 德雷克塞尔大学 | 治疗帕金森病中运动障碍的d3多巴胺受体激动剂 |
US8835472B2 (en) * | 2010-09-02 | 2014-09-16 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
BR112013032199A2 (pt) | 2011-06-14 | 2017-12-12 | Bikam Pharmaceuticals Inc | ligantes de ligação à opsina, composições e métodos de utilização |
US9499464B2 (en) | 2011-10-19 | 2016-11-22 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
BR112014012997A2 (pt) | 2011-11-30 | 2017-06-13 | Bikam Pharmaceuticals Inc | ligantes que se ligam à opsina, composições e métodos de uso |
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