IT1197348B - Cinnamilammine, processo per la loro preparazione e composizioni farmaceutiche che le contengono - Google Patents

Cinnamilammine, processo per la loro preparazione e composizioni farmaceutiche che le contengono

Info

Publication number
IT1197348B
IT1197348B IT21857/86A IT2185786A IT1197348B IT 1197348 B IT1197348 B IT 1197348B IT 21857/86 A IT21857/86 A IT 21857/86A IT 2185786 A IT2185786 A IT 2185786A IT 1197348 B IT1197348 B IT 1197348B
Authority
IT
Italy
Prior art keywords
chem
amino
groups
alkyl
hydrogen
Prior art date
Application number
IT21857/86A
Other languages
English (en)
Other versions
IT8621857A1 (it
IT8621857A0 (it
Inventor
E Menta
S Spinelli
C A Gandolfi
M Frigerio
O Tofanetti
S Tognella
Original Assignee
Boehringer Biochemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Srl filed Critical Boehringer Biochemia Srl
Priority to IT21857/86A priority Critical patent/IT1197348B/it
Publication of IT8621857A0 publication Critical patent/IT8621857A0/it
Priority to EP87114175A priority patent/EP0266549B1/en
Priority to AT87114175T priority patent/ATE64589T1/de
Priority to DE8787114175T priority patent/DE3770913D1/de
Publication of IT8621857A1 publication Critical patent/IT8621857A1/it
Application granted granted Critical
Publication of IT1197348B publication Critical patent/IT1197348B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT21857/86A 1986-09-30 1986-09-30 Cinnamilammine, processo per la loro preparazione e composizioni farmaceutiche che le contengono IT1197348B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT21857/86A IT1197348B (it) 1986-09-30 1986-09-30 Cinnamilammine, processo per la loro preparazione e composizioni farmaceutiche che le contengono
EP87114175A EP0266549B1 (en) 1986-09-30 1987-09-29 Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them
AT87114175T ATE64589T1 (de) 1986-09-30 1987-09-29 Cinnamylamine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE8787114175T DE3770913D1 (de) 1986-09-30 1987-09-29 Cinnamylamine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21857/86A IT1197348B (it) 1986-09-30 1986-09-30 Cinnamilammine, processo per la loro preparazione e composizioni farmaceutiche che le contengono

Publications (3)

Publication Number Publication Date
IT8621857A0 IT8621857A0 (it) 1986-09-30
IT8621857A1 IT8621857A1 (it) 1988-03-30
IT1197348B true IT1197348B (it) 1988-11-30

Family

ID=11187841

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21857/86A IT1197348B (it) 1986-09-30 1986-09-30 Cinnamilammine, processo per la loro preparazione e composizioni farmaceutiche che le contengono

Country Status (4)

Country Link
EP (1) EP0266549B1 (it)
AT (1) ATE64589T1 (it)
DE (1) DE3770913D1 (it)
IT (1) IT1197348B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4206528A1 (de) * 1992-03-02 1993-09-09 Bayer Ag Cyanalken-derivate, verfahren zu ihrer herstellung und ihre verwendung als mikrobizid fuer den materialschutz
US6897305B2 (en) * 1998-06-08 2005-05-24 Theravance, Inc. Calcium channel drugs and uses
US7101909B2 (en) 1998-10-12 2006-09-05 Theravance, Inc. Calcium channel drugs and uses
MY167602A (en) * 2007-11-01 2018-09-20 Acucela Inc Amine derivatives compounds for treating ophthalmic diseases and disorders
EP3670498A1 (en) * 2018-12-17 2020-06-24 Gottfried Wilhelm Leibniz Universität Hannover Compounds for treatment of hepaci virus infection and method for determining therapy of hepaci virus infection, in particular, hcv infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2831864A (en) * 1957-02-13 1958-04-22 Allied Lab Inc 1-p-alkoxyphenyl-1-alkyl-3-piperidino-1-propenes
JPS61161272A (ja) * 1985-01-11 1986-07-21 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物

Also Published As

Publication number Publication date
EP0266549B1 (en) 1991-06-19
IT8621857A1 (it) 1988-03-30
IT8621857A0 (it) 1986-09-30
DE3770913D1 (de) 1991-07-25
EP0266549A1 (en) 1988-05-11
ATE64589T1 (de) 1991-07-15

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