CL2009000135A1 - Compuestos derivados de 1,4-benzodiazepinas sustituidas, inhibidores de dipeptidilpeptidasa iv (dpp-iv); composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento de enfermedades tales como diabetes tipo 2, cataratas, glaucoma, hipertrofia prostatica benigna, cancer, entre otras; compuestos intermediarios. - Google Patents

Compuestos derivados de 1,4-benzodiazepinas sustituidas, inhibidores de dipeptidilpeptidasa iv (dpp-iv); composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento de enfermedades tales como diabetes tipo 2, cataratas, glaucoma, hipertrofia prostatica benigna, cancer, entre otras; compuestos intermediarios.

Info

Publication number
CL2009000135A1
CL2009000135A1 CL2009000135A CL2009000135A CL2009000135A1 CL 2009000135 A1 CL2009000135 A1 CL 2009000135A1 CL 2009000135 A CL2009000135 A CL 2009000135A CL 2009000135 A CL2009000135 A CL 2009000135A CL 2009000135 A1 CL2009000135 A1 CL 2009000135A1
Authority
CL
Chile
Prior art keywords
cataracts
benzodiazepines
glaucoma
cancer
diseases
Prior art date
Application number
CL2009000135A
Other languages
English (en)
Inventor
Jain Rajesh
Singh Nishan
Kumar Sharma Sudhir
Trehan Sanjay
Kaur Nanda Gurmeet
Das Jagattaran
Kumar Magadi Sitaram
Original Assignee
M/S Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M/S Panacea Biotec Ltd filed Critical M/S Panacea Biotec Ltd
Publication of CL2009000135A1 publication Critical patent/CL2009000135A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
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    • C07D—HETEROCYCLIC COMPOUNDS
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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

Compuestos derivados de 1,4-benzodiazepinas; proceso de preparación; composición farmacéutica; y su uso para la profilaxis y el tratamiento de enfermedades, tales como, cataratas, glaucoma, hipertrofia prostática benigna, osteoporosis, dolor, epilepsia, Enfermedad de Parkinson, trastornos gastrointestinales y cáncer entre otras.
CL2009000135A 2008-01-24 2009-01-23 Compuestos derivados de 1,4-benzodiazepinas sustituidas, inhibidores de dipeptidilpeptidasa iv (dpp-iv); composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento de enfermedades tales como diabetes tipo 2, cataratas, glaucoma, hipertrofia prostatica benigna, cancer, entre otras; compuestos intermediarios. CL2009000135A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN202DE2008 2008-01-24
IN688DE2008 2008-03-18

Publications (1)

Publication Number Publication Date
CL2009000135A1 true CL2009000135A1 (es) 2009-10-09

Family

ID=40474786

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009000135A CL2009000135A1 (es) 2008-01-24 2009-01-23 Compuestos derivados de 1,4-benzodiazepinas sustituidas, inhibidores de dipeptidilpeptidasa iv (dpp-iv); composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento de enfermedades tales como diabetes tipo 2, cataratas, glaucoma, hipertrofia prostatica benigna, cancer, entre otras; compuestos intermediarios.

Country Status (14)

Country Link
US (1) US8455479B2 (es)
EP (1) EP2250157B1 (es)
JP (1) JP5640208B2 (es)
KR (1) KR20100113122A (es)
CN (1) CN101925586B (es)
AP (1) AP2010005364A0 (es)
AR (1) AR070520A1 (es)
AU (1) AU2009207297B2 (es)
BR (1) BRPI0906705A2 (es)
CA (1) CA2712685A1 (es)
CL (1) CL2009000135A1 (es)
EA (1) EA018612B1 (es)
PE (1) PE20091353A1 (es)
WO (1) WO2009093269A1 (es)

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US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2012035549A2 (en) 2010-09-13 2012-03-22 Panacea Biotec Ltd An improved process for the synthesis of beta amino acid derivatives
CN102617566B (zh) * 2011-01-30 2015-03-04 山东轩竹医药科技有限公司 吡啶并咪唑烷衍生物
CN102241678B (zh) * 2011-04-26 2014-10-29 辽宁利锋科技开发有限公司 含有脂环结构化合物的抗肿瘤作用与应用
CN104230935A (zh) * 2011-04-26 2014-12-24 辽宁利锋科技开发有限公司 含有脂环结构化合物的抗肿瘤作用与应用
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
IN2015DN03795A (es) 2012-10-24 2015-10-02 Inserm Inst Nat De La Santé Et De La Rech Médicale
KR20160028241A (ko) 2014-09-03 2016-03-11 김형도 목욕탕용 순환배관 슬러지 제거방법
EP3273981B1 (en) 2015-03-24 2020-04-29 INSERM - Institut National de la Santé et de la Recherche Médicale Method and pharmaceutical composition for use in the treatment of diabetes
ES2882066T3 (es) * 2016-02-15 2021-12-01 Univ Michigan Regents 1,4-oxazepinas fusionadas y análogos relacionados como inhibidores de bromodominio BET
CN106883152A (zh) * 2017-04-07 2017-06-23 上海应用技术大学 一种β‑氨基酮的制备方法
CN108084187A (zh) * 2017-12-15 2018-05-29 宜昌人福药业有限责任公司 苯并二氮杂*类氢化物
IL302665A (en) * 2020-11-06 2023-07-01 Cytokinetics Inc Bicyclic 1,4-diazepenones and their therapeutic uses

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EP2250157A1 (en) 2010-11-17
AU2009207297B2 (en) 2011-11-10
CN101925586A (zh) 2010-12-22
WO2009093269A1 (en) 2009-07-30
CN101925586B (zh) 2014-05-07
AR070520A1 (es) 2010-04-14
PE20091353A1 (es) 2009-09-05
US8455479B2 (en) 2013-06-04
WO2009093269A9 (en) 2009-10-15
CA2712685A1 (en) 2009-07-30
US20100311732A1 (en) 2010-12-09
AP2010005364A0 (en) 2010-08-31
BRPI0906705A2 (pt) 2015-06-30
JP5640208B2 (ja) 2014-12-17
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EA201070864A1 (ru) 2011-02-28
EP2250157B1 (en) 2014-11-05

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