CH623337A5 - - Google Patents

Download PDF

Info

Publication number
CH623337A5
CH623337A5 CH1195176A CH1195176A CH623337A5 CH 623337 A5 CH623337 A5 CH 623337A5 CH 1195176 A CH1195176 A CH 1195176A CH 1195176 A CH1195176 A CH 1195176A CH 623337 A5 CH623337 A5 CH 623337A5
Authority
CH
Switzerland
Prior art keywords
lactone
pregn
oxo
carboxylic acid
dihydroxy
Prior art date
Application number
CH1195176A
Other languages
German (de)
English (en)
Inventor
Aziz Karim
William John Marsheck
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of CH623337A5 publication Critical patent/CH623337A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH1195176A 1975-09-22 1976-09-21 CH623337A5 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/615,412 US3972871A (en) 1975-09-22 1975-09-22 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Publications (1)

Publication Number Publication Date
CH623337A5 true CH623337A5 (fi) 1981-05-29

Family

ID=24465262

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1195176A CH623337A5 (fi) 1975-09-22 1976-09-21

Country Status (21)

Country Link
US (1) US3972871A (fi)
JP (1) JPS5248657A (fi)
AT (1) AT352305B (fi)
AU (1) AU499083B2 (fi)
BE (1) BE846437A (fi)
CA (1) CA1071620A (fi)
CH (1) CH623337A5 (fi)
DE (1) DE2642400A1 (fi)
DK (1) DK138995B (fi)
ES (1) ES451701A1 (fi)
FI (1) FI55670C (fi)
FR (1) FR2324309A1 (fi)
GB (1) GB1520948A (fi)
GR (1) GR61185B (fi)
IE (1) IE44350B1 (fi)
IL (1) IL50524A (fi)
NL (1) NL7610477A (fi)
NO (1) NO143910C (fi)
NZ (1) NZ182127A (fi)
PT (1) PT65616B (fi)
SE (1) SE418295B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners
US4069219A (en) * 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
JPS6063577U (ja) * 1983-10-07 1985-05-04 東レ株式会社 糸条のインタ−レ−ス装置
DK0973791T3 (da) * 1995-12-11 2007-09-17 Searle Llc Fremgangsmåde til fremstilling af en epoxyforbindelse
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237143A1 (de) * 1972-07-28 1974-02-14 Hoechst Ag Verfahren zur herstellung von beta(3-keto-7alpha-acetylthio-17beta-hydroxy4-androsten-17alpha-yl)-propionsaeuregamma-lacton und dessen 1-dehydro-derivat
GB1368006A (en) * 1972-08-24 1974-09-25 Searle & Co 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Also Published As

Publication number Publication date
PT65616B (en) 1978-04-05
DK138995B (da) 1978-11-27
BE846437A (fr) 1977-03-22
FI55670C (fi) 1979-09-10
IL50524A0 (en) 1976-11-30
GB1520948A (en) 1978-08-09
SE418295B (sv) 1981-05-18
NL7610477A (nl) 1977-03-24
DK425176A (fi) 1977-03-23
AT352305B (de) 1979-09-10
IE44350B1 (en) 1981-11-04
IE44350L (en) 1977-03-22
US3972871A (en) 1976-08-03
NO143910C (no) 1981-06-03
NO143910B (no) 1981-01-26
FR2324309B1 (fi) 1979-03-02
IL50524A (en) 1979-12-30
DE2642400A1 (de) 1977-03-24
DK138995C (fi) 1979-05-14
ES451701A1 (es) 1978-01-01
FR2324309A1 (fr) 1977-04-15
AU499083B2 (en) 1979-04-05
SE7610449L (sv) 1977-03-23
GR61185B (en) 1978-10-05
JPS5248657A (en) 1977-04-18
CA1071620A (en) 1980-02-12
AU1796276A (en) 1978-04-06
ATA698476A (de) 1979-02-15
FI762690A (fi) 1977-03-23
PT65616A (en) 1976-10-01
FI55670B (fi) 1979-05-31
NO763231L (no) 1977-03-23
NZ182127A (en) 1978-11-13

Similar Documents

Publication Publication Date Title
DE2513212C2 (de) Methyl-7-[3-hydroxy-2-(4-hydroxy-4-methyl-trans-1-octenyl)-5-oxocyclopentan]-1-heptanoat, Verfahren zu dessen Herstellung und diese Verbindung enthaltende Präparate
DE2760005C2 (de) Optisch aktive Norpinene und Verfahren zu ihrer Herstellung
DE2323215B2 (de) Pregna-1,4-dien-11-ol-3,20-dione, verfahren zu deren herstellung und sie enthaltende arzneimittel
DE2710242A1 (de) 5-eckige klammer auf 1,1-diphenyl- 3-(5- oder 6-hydroxy-2-azabicyclo eckige klammer auf 2,2,2 eckige klammer zu oct-2-yl)propyl eckige klammer zu -2- alkyl-1,3,4-oxadiazole und verwandte verbindungen
DE2651773C3 (de) 14-Acyloxy-daunorubicine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
CH637408A5 (de) Verfahren zur herstellung von 6-fluor-17-alpha-pregnanderivaten.
CH623337A5 (fi)
DD210027B3 (de) Verfahren zur herstellung von carbacyclinderivaten
CH509297A (de) Verfahren zur Herstellung von in 17-Stellung durch ungesättigte Kohlenwasserstoffreste substituierten 11,13B-Dialkylgon-4-en-3,17B-diolen
DE3028643C2 (fi)
DE2700434A1 (de) Prostaglandin-derivate, verfahren zu ihrer herstellung und arzneipraeparate
EP0313935B1 (de) Enolether von 6-Chlor-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno(2,3-e)-1,2-thiazin-3-carbonsäureamid-1,1-dioxid, ein Verfahren zu ihrer Herstellung sowie ihre Verwendung
DE2167181B1 (de) Methyl-N-acetyl-6,7-aziridino-6-desamino-7-desoxy-2,3,4-tri-0-acetyl-alpha-thiolincosaminid und Verfahren zu dessen Herstellung
EP0013955B1 (de) Neue Analoga von Prostacyclin, deren Zwischenprodukte, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel
DE2443746A1 (de) 4',5-dihydro-7alpha-alkoxycarbonylspiro eckige klammer auf androst-4-en17,2'(3'h)-furan eckige klammer zu -3-one und entsprechende delta hoch 1,4-verbindungen
DE1695500C3 (de) Verfahren zum Herstellen von 1-Methyl-S-nitrobnidazolverbindungen
DE2361391A1 (de) 2-methyl-5-nitro-1-(2-phenylthioaethyl) imidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
CH639950A5 (de) Verfahren zur herstellung von neuen 13-thiaprostansaeurederivaten.
DE2709347A1 (de) Erythro-15,16-dioxyprostensaeuren und -ester sowie verfahren zu ihrer herstellung
DE2319873C2 (de) 16-O-Alkylderivate von Gitoxigenin-digitoxosiden, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2553065A1 (de) (6s)-17'-hydroxy-3'-oxospiro- eckige klammer auf oxiran-2,6'-(17alpha)- pregn-(4)-en eckige klammer zu -21'-carbonsaeure-gamma-lacton und dessen delta hoch 1,4 -analoges, verfahren zur herstellung dieser verbindungen und pharmazeutische zubereitung, die diese verbindungen enthaelt
DE2650366A1 (de) Antitumor - praeparat
DE2435331C2 (de) Analoga von Prostansäuren und Verfahren zu ihrer Herstellung sowie diese Analoga von Prostansäuren enthaltende Arzneimittel
DE3327811A1 (de) Neue valepotriathydrinhaltige arzneimittel
DE1468681C3 (de) 17beta-Tetrahydropyranyloxy verbindungen der Androstanreihe sowie Verfahren zu ihrer Herstellung und Heilmittel

Legal Events

Date Code Title Description
PL Patent ceased