CA2012634A1 - Tyrphostines pour le traitement des allergies et des affections inflammatoires et cardiovasculaires - Google Patents

Tyrphostines pour le traitement des allergies et des affections inflammatoires et cardiovasculaires

Info

Publication number
CA2012634A1
CA2012634A1 CA 2012634 CA2012634A CA2012634A1 CA 2012634 A1 CA2012634 A1 CA 2012634A1 CA 2012634 CA2012634 CA 2012634 CA 2012634 A CA2012634 A CA 2012634A CA 2012634 A1 CA2012634 A1 CA 2012634A1
Authority
CA
Canada
Prior art keywords
composition
co2h
nhcho
eto
proline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2012634
Other languages
English (en)
Inventor
Hassan Salari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Priority to CA 2012634 priority Critical patent/CA2012634A1/fr
Publication of CA2012634A1 publication Critical patent/CA2012634A1/fr
Abandoned legal-status Critical Current

Links

CA 2012634 1990-03-20 1990-03-20 Tyrphostines pour le traitement des allergies et des affections inflammatoires et cardiovasculaires Abandoned CA2012634A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2012634 CA2012634A1 (fr) 1990-03-20 1990-03-20 Tyrphostines pour le traitement des allergies et des affections inflammatoires et cardiovasculaires

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2012634 CA2012634A1 (fr) 1990-03-20 1990-03-20 Tyrphostines pour le traitement des allergies et des affections inflammatoires et cardiovasculaires

Publications (1)

Publication Number Publication Date
CA2012634A1 true CA2012634A1 (fr) 1991-09-20

Family

ID=4144558

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2012634 Abandoned CA2012634A1 (fr) 1990-03-20 1990-03-20 Tyrphostines pour le traitement des allergies et des affections inflammatoires et cardiovasculaires

Country Status (1)

Country Link
CA (1) CA2012634A1 (fr)

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995002420A2 (fr) * 1993-07-15 1995-01-26 Cancer Research Campaign Technology Ltd. Bioprecurseurs d'inhibiteurs de la tyrosine-kinase de proteines
US5792783A (en) * 1995-06-07 1998-08-11 Sugen, Inc. 3-heteroaryl-2-indolinone compounds for the treatment of disease
US6451838B1 (en) 2000-05-24 2002-09-17 Pharmacia & Upjohn Company 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6531502B1 (en) 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
US6569868B2 (en) 1998-04-16 2003-05-27 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
US6573293B2 (en) 2000-02-15 2003-06-03 Sugen, Inc. Pyrrole substituted 2-indolinone protein kinase inhibitors
US6599902B2 (en) 2001-05-30 2003-07-29 Sugen, Inc. 5-aralkysufonyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
US6642232B2 (en) 2001-10-10 2003-11-04 Sugen, Inc. 3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors
US6653308B2 (en) 2001-02-15 2003-11-25 Sugen, Inc. 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors
US6706709B2 (en) 2000-06-02 2004-03-16 Sugen, Inc. Indolinone derivatives as protein kinase/phosphatase inhibitors
EP1427401A2 (fr) * 2001-08-31 2004-06-16 The Research Foundation Of State University Of New York Methode permettant de reduire l'hypertension et l'insuffisance cardiaque
WO2005000281A2 (fr) * 2003-06-24 2005-01-06 Actelion Pharmaceuticals Ltd. Derives de pyrazolidinedione
US6906093B2 (en) 1995-06-07 2005-06-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
EP1585745A1 (fr) * 2002-12-24 2005-10-19 Arthron Limited Composes et compositions modulant le recepteur fc
WO2007020935A1 (fr) * 2005-08-17 2007-02-22 Ono Pharmaceutical Co., Ltd. Agent thérapeutique pour soulager la douleur, comprenant un récepteur p2y12 et/ou un bloqueur de récepteur p2y14
US7202265B2 (en) 1997-08-20 2007-04-10 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
WO2013098416A3 (fr) * 2011-12-30 2013-08-15 Ecole Nationale Superieure De Chimie De Clermont Ferrand Composes anti-douleur
CN109602735A (zh) * 2018-12-07 2019-04-12 广州市妇女儿童医疗中心 预防和/或治疗肠道疾病的药物及α-氰基-4-羟基肉桂酸的应用
KR20210057305A (ko) * 2019-11-12 2021-05-21 아주대학교산학협력단 신경염증질환의 예방 또는 치료용 신규 화합물 및 이를 포함하는 약제학적 조성물

Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995002420A2 (fr) * 1993-07-15 1995-01-26 Cancer Research Campaign Technology Ltd. Bioprecurseurs d'inhibiteurs de la tyrosine-kinase de proteines
WO1995002420A3 (fr) * 1993-07-15 1995-03-16 Caroline Joy Springer Bioprecurseurs d'inhibiteurs de la tyrosine-kinase de proteines
US5792783A (en) * 1995-06-07 1998-08-11 Sugen, Inc. 3-heteroaryl-2-indolinone compounds for the treatment of disease
US5834504A (en) * 1995-06-07 1998-11-10 Sugen, Inc. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
US5883113A (en) * 1995-06-07 1999-03-16 Sugen, Inc. 3-(4'-Bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease
US5883116A (en) * 1995-06-07 1999-03-16 Sugen, Inc. 3-(2'-alkoxybenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease
US5886020A (en) * 1995-06-07 1999-03-23 Sugen, Inc. 3-(4'-dimethylaminobenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease
US6225335B1 (en) 1995-06-07 2001-05-01 Sugen, Inc. 3-(4′-bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease
US6469032B2 (en) 1995-06-07 2002-10-22 Sugen, Inc. 3-(4′-bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease
US6906093B2 (en) 1995-06-07 2005-06-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US7202265B2 (en) 1997-08-20 2007-04-10 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US6531502B1 (en) 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
US6569868B2 (en) 1998-04-16 2003-05-27 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
US6855730B2 (en) 1998-08-05 2005-02-15 Sugen, Inc. 3-methylidenyl-2-indolinone modulators of protein kinase
US6573293B2 (en) 2000-02-15 2003-06-03 Sugen, Inc. Pyrrole substituted 2-indolinone protein kinase inhibitors
US7572924B2 (en) 2000-02-15 2009-08-11 Sugen, Inc. Pyrrole substituted 2-indolinone protein kinase inhibitors
US7125905B2 (en) 2000-02-15 2006-10-24 Agouron Pharmaceuticals, Inc. Pyrrole substituted 2-indolinone protein kinase inhibitors
US7112603B2 (en) 2000-05-24 2006-09-26 Agouron Pharmaceuticals, Inc. Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7008943B2 (en) 2000-05-24 2006-03-07 Pharmacia & Upjohn Company 1-(Pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6716870B2 (en) 2000-05-24 2004-04-06 Sugen, Inc. Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6451838B1 (en) 2000-05-24 2002-09-17 Pharmacia & Upjohn Company 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6710067B2 (en) 2000-05-24 2004-03-23 Sugen Incorporated Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7053113B2 (en) 2000-05-24 2006-05-30 Sugen, Inc. Mannich base prodrugs of 3-(pyrrol-2-yl-methylidene)-2-indolinone derivatives
US6482848B2 (en) 2000-05-24 2002-11-19 Sugen Incorporated Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7071332B2 (en) 2000-06-02 2006-07-04 Sugen, Inc. Indolinone derivatives as protein kinase/phosphatase inhibitors
US6706709B2 (en) 2000-06-02 2004-03-16 Sugen, Inc. Indolinone derivatives as protein kinase/phosphatase inhibitors
US7179910B2 (en) 2001-02-15 2007-02-20 Agouron Pharmaceuticals, Inc. 3-(4-amidopyrrol-2-ylmethlidene)-2-indolinone derivatives as protein kinase inhibitors
US7582756B2 (en) 2001-02-15 2009-09-01 Sugen, Inc. 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors
US6653308B2 (en) 2001-02-15 2003-11-25 Sugen, Inc. 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors
US7256189B2 (en) 2001-02-15 2007-08-14 Sugen, Inc. 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone der derivatives as protein kinase inhibitors
US6599902B2 (en) 2001-05-30 2003-07-29 Sugen, Inc. 5-aralkysufonyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
EP1427401A4 (fr) * 2001-08-31 2009-04-29 Univ New York State Res Found Methode permettant de reduire l'hypertension et l'insuffisance cardiaque
EP1427401A2 (fr) * 2001-08-31 2004-06-16 The Research Foundation Of State University Of New York Methode permettant de reduire l'hypertension et l'insuffisance cardiaque
US6642232B2 (en) 2001-10-10 2003-11-04 Sugen, Inc. 3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors
EP1585745A4 (fr) * 2002-12-24 2008-07-09 Trillium Therapeutics Inc Composes et compositions modulant le recepteur fc
US7910770B2 (en) 2002-12-24 2011-03-22 Trillium Therapeutics Inc. Fc receptor modulating compounds and compositions
EP1585745A1 (fr) * 2002-12-24 2005-10-19 Arthron Limited Composes et compositions modulant le recepteur fc
WO2005000281A2 (fr) * 2003-06-24 2005-01-06 Actelion Pharmaceuticals Ltd. Derives de pyrazolidinedione
JP2007506661A (ja) * 2003-06-24 2007-03-22 アクテリオン　ファマシューティカルズ　リミテッド ピラゾリジンジオン誘導体
WO2005002574A1 (fr) * 2003-06-24 2005-01-13 Actelion Pharmaceuticals Ltd Derives de pyrazolidinedione et leur utilisation en tant qu'inhibiteurs de l'agregation des plaquettes
WO2005000281A3 (fr) * 2003-06-24 2005-04-14 Actelion Pharmaceuticals Ltd Derives de pyrazolidinedione
WO2007020935A1 (fr) * 2005-08-17 2007-02-22 Ono Pharmaceutical Co., Ltd. Agent thérapeutique pour soulager la douleur, comprenant un récepteur p2y12 et/ou un bloqueur de récepteur p2y14
WO2013098416A3 (fr) * 2011-12-30 2013-08-15 Ecole Nationale Superieure De Chimie De Clermont Ferrand Composes anti-douleur
CN104093706A (zh) * 2011-12-30 2014-10-08 克莱蒙费朗国立高等化工学校 疼痛缓解化合物
US10214476B2 (en) 2011-12-30 2019-02-26 Ecole Nationale Superieure De Chimie De Clermont Ferrand Pain relief compounds
CN109602735A (zh) * 2018-12-07 2019-04-12 广州市妇女儿童医疗中心 预防和/或治疗肠道疾病的药物及α-氰基-4-羟基肉桂酸的应用
KR20210057305A (ko) * 2019-11-12 2021-05-21 아주대학교산학협력단 신경염증질환의 예방 또는 치료용 신규 화합물 및 이를 포함하는 약제학적 조성물
KR102516957B1 (ko) * 2019-11-12 2023-03-31 아주대학교산학협력단 신경염증질환의 예방 또는 치료용 신규 화합물 및 이를 포함하는 약제학적 조성물

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