CA1064906A - Process for the preparation of new 16-ethers of fusidic acid derivatives - Google Patents

Process for the preparation of new 16-ethers of fusidic acid derivatives

Info

Publication number
CA1064906A
CA1064906A CA255,603A CA255603A CA1064906A CA 1064906 A CA1064906 A CA 1064906A CA 255603 A CA255603 A CA 255603A CA 1064906 A CA1064906 A CA 1064906A
Authority
CA
Canada
Prior art keywords
acid
radical
compound
deacetoxy
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA255,603A
Other languages
English (en)
French (fr)
Inventor
Welf Von Daehne
Poul R. Rasmussen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB26989/75A external-priority patent/GB1523803A/en
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Application granted granted Critical
Publication of CA1064906A publication Critical patent/CA1064906A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CA255,603A 1975-06-25 1976-06-24 Process for the preparation of new 16-ethers of fusidic acid derivatives Expired CA1064906A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB26989/75A GB1523803A (en) 1975-06-25 1975-06-25 16-ethers of fusidic acid derivatives
GB4622975 1975-11-07

Publications (1)

Publication Number Publication Date
CA1064906A true CA1064906A (en) 1979-10-23

Family

ID=26258548

Family Applications (1)

Application Number Title Priority Date Filing Date
CA255,603A Expired CA1064906A (en) 1975-06-25 1976-06-24 Process for the preparation of new 16-ethers of fusidic acid derivatives

Country Status (18)

Country Link
JP (1) JPS523051A (it)
AT (1) AT345979B (it)
AU (1) AU500027B2 (it)
CA (1) CA1064906A (it)
DE (1) DE2628360C2 (it)
DK (1) DK143905C (it)
ES (1) ES449257A1 (it)
FI (1) FI55852C (it)
FR (1) FR2315296A1 (it)
GR (1) GR60362B (it)
IE (1) IE43478B1 (it)
IT (1) IT1062245B (it)
LU (1) LU75239A1 (it)
NL (1) NL7606983A (it)
NZ (1) NZ181107A (it)
PT (1) PT65261A (it)
SE (1) SE7607322L (it)
SU (1) SU799670A3 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1581335A (en) * 1976-07-05 1980-12-10 Leo Pharm Prod Ltd 16-s-acyl derivatives of fusidic acid
US4548922A (en) * 1983-06-06 1985-10-22 Beth Israel Hospital Drug administration
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
ATE230994T1 (de) * 1989-07-07 2003-02-15 Endorech Inc Methode zur behandlung androgenbedingter krankheiten
SK140494A3 (en) * 1992-05-21 1995-07-11 Endorecherche Inc Inhibitors of testosterone 5-alpha-reductase activity

Also Published As

Publication number Publication date
FI55852B (fi) 1979-06-29
JPS6350360B2 (it) 1988-10-07
DE2628360C2 (de) 1986-11-06
AU1525076A (en) 1978-01-05
NZ181107A (en) 1978-11-13
SE7607322L (sv) 1976-12-26
IE43478B1 (en) 1981-03-11
FR2315296A1 (fr) 1977-01-21
AT345979B (de) 1978-10-10
GR60362B (en) 1978-05-19
DK143905C (da) 1982-04-19
AU500027B2 (en) 1979-05-10
DK143905B (da) 1981-10-26
LU75239A1 (it) 1977-03-16
FI55852C (fi) 1979-10-10
FI761863A (it) 1976-12-26
IT1062245B (it) 1983-09-20
ES449257A1 (es) 1977-12-16
IE43478L (en) 1976-12-25
DE2628360A1 (de) 1977-01-13
ATA438776A (de) 1978-02-15
PT65261B (it) 1977-12-07
JPS523051A (en) 1977-01-11
FR2315296B1 (it) 1980-11-07
SU799670A3 (ru) 1981-01-23
DK285776A (da) 1976-12-26
NL7606983A (nl) 1976-12-28
PT65261A (en) 1976-07-01

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