BRPI0413363A - formas de dosagem fornecendo liberação controlada de inibidores de proteìna de transferência de ésteres de colesterila e liberação imediata de inibidores de hmg-coa redutase - Google Patents
formas de dosagem fornecendo liberação controlada de inibidores de proteìna de transferência de ésteres de colesterila e liberação imediata de inibidores de hmg-coa redutaseInfo
- Publication number
- BRPI0413363A BRPI0413363A BRPI0413363-3A BRPI0413363A BRPI0413363A BR PI0413363 A BRPI0413363 A BR PI0413363A BR PI0413363 A BRPI0413363 A BR PI0413363A BR PI0413363 A BRPI0413363 A BR PI0413363A
- Authority
- BR
- Brazil
- Prior art keywords
- hmg
- inhibitors
- transfer protein
- ester transfer
- coa reductase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"FORMAS DE DOSAGEM FORNECENDO LIBERAçãO CONTROLADA DE INIBIDORES DE PROTEìNA DE TRANSFERêNCIA DE éSTERES DE COLESTERILA E LIBERAçãO IMEDIATA DE INIBIDORES DE HMG-CoA REDUTASE". Uma forma de dosagem que compreende um inibidor da proteína de transferência de ésteres de colesterila em uma forma com solubilidade melhorada e um inibidor de HMG-CoA redutase, em que a forma de dosagem proporciona liberação imediata do inibidor de HMG-CoA redutase e liberação controlada do inibidor da proteína de transferência de ésteres de colesterila.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49240703P | 2003-08-04 | 2003-08-04 | |
PCT/IB2004/002457 WO2005011634A1 (en) | 2003-08-04 | 2004-07-21 | Dosage forms providing controlled release of cholesteryl ester transfer protein inhibitors and immediate release of hmg-coa reductase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0413363A true BRPI0413363A (pt) | 2006-10-10 |
Family
ID=34115617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0413363-3A BRPI0413363A (pt) | 2003-08-04 | 2004-07-21 | formas de dosagem fornecendo liberação controlada de inibidores de proteìna de transferência de ésteres de colesterila e liberação imediata de inibidores de hmg-coa redutase |
Country Status (16)
Country | Link |
---|---|
US (1) | US20050038007A1 (pt) |
EP (1) | EP1653926A1 (pt) |
JP (1) | JP2007501217A (pt) |
KR (1) | KR20060033033A (pt) |
CN (2) | CN1863511A (pt) |
AR (1) | AR045203A1 (pt) |
AU (1) | AU2004261058A1 (pt) |
BR (1) | BRPI0413363A (pt) |
CA (1) | CA2534371A1 (pt) |
IL (1) | IL172875A0 (pt) |
MX (1) | MXPA06001506A (pt) |
NO (1) | NO20061072L (pt) |
RU (1) | RU2006102981A (pt) |
TW (1) | TW200517145A (pt) |
WO (1) | WO2005011634A1 (pt) |
ZA (2) | ZA200600179B (pt) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI393560B (zh) * | 2003-05-02 | 2013-04-21 | Japan Tobacco Inc | 包含s-〔2(〔〔1-(2-乙基丁基)環己基〕羰基〕胺基)苯基〕2-甲基丙烷硫酯及hmg輔酶a還原酶抑制劑之組合 |
EP1692444A2 (en) * | 2003-10-24 | 2006-08-23 | J. Rettenmaier & Söhne GmbH + Co. KG | Process for co-spray drying agents with dry silicified mcc |
US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
ES2644450T3 (es) | 2004-12-31 | 2017-11-29 | Dr. Reddy's Laboratories Ltd. | Nuevos derivados de bencilamina como inhibidores de CETP |
US20080145427A1 (en) * | 2005-02-03 | 2008-06-19 | Alfred Berchielli | Dosage Forms Providing Controlled and Immediate Release of Cholesteryl Ester Transfer Protein Inhibitors and Immediate Release of Hmg-Coa Reductase Inhibitors |
US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
CN1331476C (zh) * | 2005-07-05 | 2007-08-15 | 凌沛学 | 一种辅酶a舌下含片及其制备方法 |
US8486983B2 (en) | 2005-12-05 | 2013-07-16 | Merck Sharp & Dohme Corp. | Self-emulsifying formulations of CETP inhibitors |
KR100742571B1 (ko) * | 2006-03-02 | 2007-07-25 | 충남대학교산학협력단 | 초임계유체 공정을 이용한 무정형 아토르바스타틴 칼슘염및 그 제조방법 |
CA2612989A1 (en) * | 2006-05-08 | 2007-11-08 | Mcneil-Ppc, Inc. | Osmotic dosage form |
WO2008065502A1 (en) * | 2006-11-29 | 2008-06-05 | Pfizer Products Inc. | Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein |
KR100885029B1 (ko) * | 2007-02-07 | 2009-02-23 | 지엘팜텍 주식회사 | 경구투여용 서방성 삼중정제 |
WO2008115529A1 (en) * | 2007-03-20 | 2008-09-25 | Reliant Pharmaceuticals, Inc. | Compositions comprising omega-3 fatty acids and cetp inhibitors |
WO2008135855A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
US20100215747A1 (en) * | 2007-07-13 | 2010-08-26 | Corey Jay Bloom | Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers |
TW201016761A (en) * | 2008-10-30 | 2010-05-01 | Univ Nat Taiwan | Microporous film and preparation and use thereof |
EP2379562A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Bicyclic pyranone derivatives as nicotinic acid receptor agonists |
EP2379547A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
AU2010260208B2 (en) | 2009-06-16 | 2014-11-13 | Bristol-Myers Squibb Holdings Ireland Unlimited Company | Dosage forms of apixaban |
US20130029970A1 (en) | 2009-07-10 | 2013-01-31 | Ironwood Pharmaceuticals, Inc | CB Receptor Agonists |
WO2011028309A1 (en) | 2009-09-04 | 2011-03-10 | University Of Toledo | PROCESSES FOR PRODUCING OPTICALLY PURE β-LACTONES FROM ALDEHYDES AND COMPOSITIONS PRODUCED THEREBY |
EA201200855A1 (ru) | 2009-12-23 | 2013-04-30 | Айронвуд Фармасьютикелз, Инк. | Модуляторы crth2 |
WO2011100359A1 (en) | 2010-02-09 | 2011-08-18 | Ironwood Pharmaceuticals, Inc. | Cannabinoid agonists |
US20130196960A1 (en) | 2010-02-09 | 2013-08-01 | Ironwood Pharmaceuticals, Inc. | Cannabinoid Receptor Agonists |
WO2011115804A1 (en) | 2010-03-17 | 2011-09-22 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
AR088020A1 (es) | 2010-06-30 | 2014-05-07 | Ironwood Pharmaceuticals Inc | Compuestos heterociclicos como estimuladores de sgc |
WO2012009134A1 (en) | 2010-07-12 | 2012-01-19 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
WO2012009137A1 (en) | 2010-07-12 | 2012-01-19 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
WO2012014923A1 (ja) * | 2010-07-29 | 2012-02-02 | 田辺工業株式会社 | 減圧噴霧乾燥方法及び減圧噴霧乾燥装置 |
US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
UA110117C2 (uk) * | 2010-11-04 | 2015-11-25 | Ф. Хоффманн-Ля Рош Аг | Композиція, що містить s-[2-([[1-(2-етилбутил)-циклогексил]-карбоніл]аміно)феніл]2-метилпропантіоат і кроскармелозу натрію |
CN107266433A (zh) | 2010-11-09 | 2017-10-20 | 铁木医药有限公司 | sGC刺激剂 |
WO2012170417A2 (en) | 2011-06-06 | 2012-12-13 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
CA2845284C (en) | 2011-08-18 | 2018-03-06 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (cetp) inhibitors |
JP6140168B2 (ja) | 2011-09-27 | 2017-05-31 | ドクター レディズ ラボラトリーズ リミテッド | アテローム性動脈硬化症の処置のために有用なコレステリルエステル転送タンパク質(cetp)インヒビターとしての5−ベンジルアミノメチル−6−アミノピラゾロ[3,4−b]ピリジン誘導体 |
CN104066731B (zh) | 2011-12-27 | 2016-06-15 | 铁木医药有限公司 | 可用作sgc刺激剂的2-苄基、3-(嘧啶-2-基)取代的吡唑类 |
US20150080381A1 (en) | 2012-04-12 | 2015-03-19 | Ironwood Pharmaceuticals, Inc. | Methods of treating alopecia and acne |
CA2869525A1 (en) * | 2012-04-30 | 2013-11-07 | F. Hoffmann-La Roche Ag | New formulation |
US9309235B2 (en) | 2012-09-18 | 2016-04-12 | Ironwood Pharmaceuticals, Inc. | SGC stimulators |
US9487508B2 (en) | 2012-09-19 | 2016-11-08 | Ironwood Pharmaceuticals, Inc. | SGC stimulators |
AU2013346501B2 (en) * | 2012-11-19 | 2017-07-13 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical compositions of CETP inhibitors |
KR101986683B1 (ko) * | 2012-12-13 | 2019-06-10 | 한미약품 주식회사 | 테트라졸 유도체를 활성 성분으로 포함하는 용해도가 개선된 고체 분산체 |
RU2015128794A (ru) * | 2012-12-20 | 2017-01-25 | КАШИВ ФАРМА, ЭлЭлСи | Композиция перорально распадающейся таблетки, обеспечивающая повышенную биодоступность |
WO2014128564A2 (en) * | 2013-02-21 | 2014-08-28 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical compositions of cetp inhibitors |
ES2774295T3 (es) | 2013-03-15 | 2020-07-20 | Cyclerion Therapeutics Inc | Estimuladores de sGC |
JP2016540017A (ja) | 2013-12-11 | 2016-12-22 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | sGC刺激物質 |
CN106102744A (zh) * | 2014-01-09 | 2016-11-09 | 维瑞斯特姆股份有限公司 | 用于治疗异常细胞生长的组合物和方法 |
JP6956005B2 (ja) * | 2014-08-28 | 2021-10-27 | デジマ・ファルマ・ベー・フェー | コレステリルエステル転送タンパク質阻害剤及びHMG CoA還元酵素阻害剤を含む医薬組成物及び治療併用剤 |
JP2017527604A (ja) | 2014-09-17 | 2017-09-21 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | sGC刺激剤 |
US20170298055A1 (en) | 2014-09-17 | 2017-10-19 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
CN107406422B (zh) | 2014-09-17 | 2022-02-01 | 赛科理音医疗有限公司 | 作为sGC刺激剂的吡唑衍生物 |
PT3507291T (pt) | 2016-09-02 | 2021-08-30 | Cyclerion Therapeutics Inc | Estimulantes de sgc bicíclicos fundidos |
EA201991147A1 (ru) | 2016-11-08 | 2019-11-29 | ЛЕЧЕНИЕ ЗАБОЛЕВАНИЙ ЦЕНТРАЛЬНОЙ НЕРВНОЙ СИСТЕМЫ С ПОМОЩЬЮ СТИМУЛЯТОРОВ sGC | |
US11180493B2 (en) | 2016-11-08 | 2021-11-23 | Cyclerion Therapeutics, Inc. | SGC stimulators |
CN107019927A (zh) * | 2017-04-18 | 2017-08-08 | 成都绿林科技有限公司 | 用于药品快速干燥的干燥机 |
CN109663373A (zh) * | 2018-12-26 | 2019-04-23 | 无锡市林洲干燥设备有限公司 | 甲维盐闭式循环喷雾干燥*** |
CN110773079B (zh) * | 2019-11-18 | 2022-03-01 | 江苏博迁新材料股份有限公司 | 一种超声喷雾法制备超细粉球的方法 |
CN115724771A (zh) * | 2021-08-30 | 2023-03-03 | 中国科学院过程工程研究所 | 一种用于制备n,n’-二苯基脲的装置***及制备n,n’-二苯基脲的工艺 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10325A (en) * | 1853-12-20 | Improvement in manure crushers and sowers | ||
US35125A (en) * | 1862-04-29 | Improvement in spring-balances | ||
EP0680320B1 (en) * | 1993-01-19 | 1999-04-14 | Warner-Lambert Company | Stable oral ci-981 formulation and process of preparing same |
PT828495E (pt) * | 1995-06-01 | 2003-01-31 | Searle & Co | Dispersoes solidas estabilizadas de misoprostol |
DE19627431A1 (de) * | 1996-07-08 | 1998-01-15 | Bayer Ag | Heterocyclisch kondensierte Pyridine |
EP1792616B1 (en) * | 1997-07-31 | 2009-12-16 | Abbott Respiratory LLC | Composition comprising an HMG-CoA inhibitor and a nicotinic acid compound for treating hyperlipidemia |
US20010006644A1 (en) * | 1997-07-31 | 2001-07-05 | David J. Bova | Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night |
US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
WO2000038722A1 (en) * | 1998-12-23 | 2000-07-06 | G.D. Searle & Co. | COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS |
ES2310164T3 (es) * | 1999-02-10 | 2009-01-01 | Pfizer Products Inc. | Dispositivo de liberacion controlada por la matriz. |
DE60042352D1 (de) * | 1999-02-10 | 2009-07-23 | Pfizer Prod Inc | Osmotisches System zur Verabreichung von Wirkstoffen, die feste amorphe Dispersionen enthalten |
US6706283B1 (en) * | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
US7115279B2 (en) * | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
US20030086972A1 (en) * | 2000-08-09 | 2003-05-08 | Appel Leah E. | Hydrogel-driven drug dosage form |
CA2419406A1 (en) * | 2000-08-15 | 2002-02-21 | Pfizer Products Inc. | Pharmaceutical combinations of torcetrapib and atorvastatin or hydroxy derivatives for the treatment of atherosclerosis, angina and low hdl levels |
EP1404300B1 (en) * | 2001-06-22 | 2009-09-30 | Pfizer Products Inc. | Pharmaceutical compositions of dispersions of drugs and neutral polymers |
HUP0400264A2 (hu) * | 2001-06-22 | 2004-08-30 | Pfizer Products Inc. | Alacsony oldékonyságú és/vagy savra érzékeny hatóanyagokat és semlegesített savas polimereket tartalmazó gyógyszerkészítmények és eljárás az előállításukra |
-
2004
- 2004-07-21 BR BRPI0413363-3A patent/BRPI0413363A/pt not_active IP Right Cessation
- 2004-07-21 KR KR1020067002353A patent/KR20060033033A/ko not_active Application Discontinuation
- 2004-07-21 CN CNA2004800290032A patent/CN1863511A/zh active Pending
- 2004-07-21 WO PCT/IB2004/002457 patent/WO2005011634A1/en active Application Filing
- 2004-07-21 MX MXPA06001506A patent/MXPA06001506A/es unknown
- 2004-07-21 AU AU2004261058A patent/AU2004261058A1/en not_active Abandoned
- 2004-07-21 RU RU2006102981/15A patent/RU2006102981A/ru not_active Application Discontinuation
- 2004-07-21 CA CA002534371A patent/CA2534371A1/en not_active Abandoned
- 2004-07-21 EP EP04744109A patent/EP1653926A1/en not_active Withdrawn
- 2004-07-21 JP JP2006522426A patent/JP2007501217A/ja active Pending
- 2004-07-27 CN CNA2004800218379A patent/CN1870978A/zh active Pending
- 2004-07-30 US US10/903,433 patent/US20050038007A1/en not_active Abandoned
- 2004-08-03 AR ARP040102760A patent/AR045203A1/es not_active Application Discontinuation
- 2004-08-03 TW TW093123237A patent/TW200517145A/zh unknown
-
2005
- 2005-12-28 IL IL172875A patent/IL172875A0/en unknown
-
2006
- 2006-01-06 ZA ZA200600179A patent/ZA200600179B/en unknown
- 2006-01-30 ZA ZA200600853A patent/ZA200600853B/en unknown
- 2006-03-06 NO NO20061072A patent/NO20061072L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20061072L (no) | 2006-05-04 |
ZA200600853B (en) | 2007-04-25 |
IL172875A0 (en) | 2006-06-11 |
TW200517145A (en) | 2005-06-01 |
KR20060033033A (ko) | 2006-04-18 |
AU2004261058A1 (en) | 2005-02-10 |
CA2534371A1 (en) | 2005-02-10 |
JP2007501217A (ja) | 2007-01-25 |
RU2006102981A (ru) | 2007-09-20 |
ZA200600179B (en) | 2007-02-28 |
EP1653926A1 (en) | 2006-05-10 |
AR045203A1 (es) | 2005-10-19 |
CN1870978A (zh) | 2006-11-29 |
CN1863511A (zh) | 2006-11-15 |
MXPA06001506A (es) | 2006-05-15 |
US20050038007A1 (en) | 2005-02-17 |
WO2005011634A1 (en) | 2005-02-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0413363A (pt) | formas de dosagem fornecendo liberação controlada de inibidores de proteìna de transferência de ésteres de colesterila e liberação imediata de inibidores de hmg-coa redutase | |
TW200638950A (en) | Dosage forms of cholesteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors | |
UY26864A1 (es) | Composiciones farmaceúticas de inhibidores de la proteína de transferencia de colesteril éster | |
MX2009010284A (es) | Inhibidores de la tirosina-cinasa de bruton. | |
EE200200411A (et) | HMG-CoA reduktaasi inhibiitorit sisaldavad farmatseutilised kompositsioonid | |
PA8564901A1 (es) | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo | |
HN2003000054A (es) | Formas de dosificacion farmaceutica de liberacion controlada de un inhibidor de la proteina de transferencia de ester de colesterilo (cetpi), a procedimientos de uso y a procedimientos de preparacion de las mismas. | |
BR0317715A (pt) | Composições e processos de uso de collajolie | |
HN2003000227A (es) | Inhibidores de quinasas | |
TW200728285A (en) | Diacylindazole derivatives as inhibitors of lipases and phospholipases | |
NO20054369L (no) | Anvendelse av en IBAT-inhibitor for behandling og profylakse av forstoppelse | |
DK1373259T3 (da) | Pyridazinonaldosereduktaseinhibitorer | |
DK1206474T3 (da) | Sulfonylphenylpyrazolforbindelser anvendelige som cox-2-inhibitorer | |
ECSP055888A (es) | Derivados de aril-quinazolin/aril-2-amino-fenil metanona que promueven la liberación de la hormona paratiroides. | |
HN2001000146A (es) | Derivados de pirazol | |
EP1740183B8 (en) | Novel use for pde5 inhibitors | |
BR0211274A (pt) | Combinação de um antagonista de receptor de aldosterona e um inibidor de hmg co-a redutase | |
TW200730513A (en) | Carbamoylbenzotriazole derivatives as inhibitors of lipases and phospholipases | |
BR0317593A (pt) | Formas de dosagem compreendendo um inibidor de cetp e um inibidor de hmg-coa reductase | |
NO20044898L (no) | Nye etonogestrel estere | |
HRP20090513T1 (en) | S-mirtazapine for the treatment of hot flush | |
HUP0401854A2 (hu) | COX-2 inhibitorokat és aszpirint tartalmazó kombinációk | |
MY146444A (en) | Benzooxazol-2-one derivatives as inhibitors of lipases and phospholipases | |
NO20080133L (no) | Azolopyridin-2-on derivater som lipase og fosfolipaseinhibitorer | |
DE60305522D1 (de) | Pharmazeutische zusammensetzung enthaltend tenatoprazol und einen entzündungshemmer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A, 5A,6A E 7A ANUIDADE(S) |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011. |