BR9911549A - Processo de produção de fitase em levedura - Google Patents
Processo de produção de fitase em leveduraInfo
- Publication number
- BR9911549A BR9911549A BR9911549-2A BR9911549A BR9911549A BR 9911549 A BR9911549 A BR 9911549A BR 9911549 A BR9911549 A BR 9911549A BR 9911549 A BR9911549 A BR 9911549A
- Authority
- BR
- Brazil
- Prior art keywords
- production process
- yeast
- phytase
- phytase production
- yeast phytase
- Prior art date
Links
- 108010011619 6-Phytase Proteins 0.000 title abstract 5
- 229940085127 phytase Drugs 0.000 title abstract 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Devices For Dispensing Beverages (AREA)
Abstract
"PROCESSO DE PRODUçãO DE FITAS EM LEVEDURA". A presente invenção refere-se a um processo para produzir um polipeptídeo ou proteína heteróloga apresentando atividade de fitase em um sistema de levedura. A invenção também proporciona proteínas com atividade de fitase que apresentam maior termoestabilidade. As cepas de levedura que produzem uma fitase heteróloga e os vetores utilizados para produzir a fitase também são proporcionados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/104,769 US6451572B1 (en) | 1998-06-25 | 1998-06-25 | Overexpression of phytase genes in yeast systems |
PCT/US1999/014106 WO1999067398A2 (en) | 1998-06-25 | 1999-06-23 | Overexpression of phytase genes in yeast systems |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9911549A true BR9911549A (pt) | 2001-03-20 |
BRPI9911549B1 BRPI9911549B1 (pt) | 2016-08-30 |
Family
ID=22302276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9911549A BRPI9911549B1 (pt) | 1998-06-25 | 1999-06-23 | processo de produção de fitase appa de escherichia coli em levedura, proteína ou polipeptídeo, vetor de expressão, e, levedura |
Country Status (18)
Country | Link |
---|---|
US (6) | US6451572B1 (pt) |
EP (3) | EP1090129B2 (pt) |
JP (2) | JP2002518052A (pt) |
KR (1) | KR100870886B1 (pt) |
CN (1) | CN100365126C (pt) |
AT (1) | ATE317904T1 (pt) |
AU (1) | AU772071B2 (pt) |
BR (1) | BRPI9911549B1 (pt) |
CA (1) | CA2332180C (pt) |
CZ (1) | CZ301680B6 (pt) |
DE (1) | DE69929886C5 (pt) |
DK (2) | DK1688500T3 (pt) |
ES (2) | ES2560661T3 (pt) |
HU (1) | HUP0102800A2 (pt) |
MX (1) | MX258391B (pt) |
PL (1) | PL345408A1 (pt) |
PT (1) | PT1688500E (pt) |
WO (1) | WO1999067398A2 (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6720014B1 (en) * | 1997-08-13 | 2004-04-13 | Diversa Corporation | Phytase-containing foodstuffs and methods of making and using them |
US6451572B1 (en) * | 1998-06-25 | 2002-09-17 | Cornell Research Foundation, Inc. | Overexpression of phytase genes in yeast systems |
US6841370B1 (en) | 1999-11-18 | 2005-01-11 | Cornell Research Foundation, Inc. | Site-directed mutagenesis of Escherichia coli phytase |
KR100375673B1 (ko) * | 2000-01-29 | 2003-03-15 | 대한민국 | 피타제 생산 효모 균주를 함유하는 사료용 조성물 |
US6737262B1 (en) * | 2000-07-11 | 2004-05-18 | Robert I. Bolla | Animal feed containing polypeptides |
JP3813055B2 (ja) * | 2000-07-26 | 2006-08-23 | ソレイ リミテッド ライアビリティ カンパニー | 高純度植物タンパク材料の製造方法 |
EP1559328A1 (en) * | 2001-03-23 | 2005-08-03 | Advanced Bionutrition Corporation | Fungal feeds for aquaculture and agriculture |
WO2003037102A2 (en) * | 2001-10-31 | 2003-05-08 | Phytex, Llc | Phytase-containing animal food and method |
TW200305430A (en) * | 2001-12-28 | 2003-11-01 | Syngenta Participations Ag | Thermotolerant phytase for animal feed |
TWI262083B (en) * | 2001-12-28 | 2006-09-21 | Syngenta Participations Ag | Microbially-expressed thermotolerant phytase for animal feed |
CN100398645C (zh) * | 2002-08-16 | 2008-07-02 | 广东肇庆星湖生物科技股份有限公司 | 用化学合成和分子进化获得酵母表达高比活植酸酶基因 |
CN100354421C (zh) * | 2002-08-16 | 2007-12-12 | 广东肇庆星湖生物科技股份有限公司 | 在甲醇酵母中高表达的耐高温植酸酶基因 |
EP1604008B1 (en) | 2002-09-13 | 2010-12-22 | Cornell Research Foundation, Inc. | Using mutations to improve aspergillus phytases |
WO2004046334A2 (en) * | 2002-11-19 | 2004-06-03 | Board Of Trustees Operating Michigan State University | Antioxidant and antimicrobial agents and methods of use thereof |
US20070184521A1 (en) * | 2003-07-03 | 2007-08-09 | Alissa Jourdan | Novel phytase and gene |
US7276362B2 (en) | 2004-01-30 | 2007-10-02 | Roche Diagnostics Operations, Inc. | Recombinant histidine-tagged inosine monophosphate dehydrogenase polypeptides |
NZ552046A (en) * | 2004-06-01 | 2010-05-28 | Prophagia Inc | Index and method of use of adapted food compositions for dysphagic persons |
CA2575905A1 (en) * | 2004-08-02 | 2006-02-09 | Universite Laval | Nutritional ingredient containing bioavailable mineral nutrients |
KR100754242B1 (ko) | 2005-08-29 | 2007-09-03 | (주)진바이오텍 | 효모 유래 프로모터를 이용한 대장균 유래 파이타제의제조방법 |
US7919297B2 (en) | 2006-02-21 | 2011-04-05 | Cornell Research Foundation, Inc. | Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase |
WO2008017066A2 (en) * | 2006-08-03 | 2008-02-07 | Cornell Research Foundation, Inc. | Phytases with improved thermal stability |
US8192734B2 (en) | 2007-07-09 | 2012-06-05 | Cornell University | Compositions and methods for bone strengthening |
EP2258854A1 (en) * | 2009-05-20 | 2010-12-08 | FH Campus Wien | Eukaryotic host cell comprising an expression enhancer |
WO2011141613A2 (es) | 2011-08-08 | 2011-11-17 | Fertinagro Nutrientes, S.L. | Nueva fitasa, procedimiento de obtencion y utilizacion de la misma |
CA2904333A1 (en) | 2013-03-08 | 2014-09-12 | Biogrammatics, Inc. | Yeast promoters for protein expression |
HUE044664T2 (hu) * | 2013-03-08 | 2019-11-28 | Keck Graduate Inst Of Applied Life Sciences | Élesztõpromóterek pichia pastorisból |
EP3657950A4 (en) * | 2017-07-27 | 2021-08-11 | Locus Agriculture IP Company, LLC | EFFICIENT PRODUCTION OF DEPICHIA YEASTS |
EP3453719A1 (en) | 2017-09-07 | 2019-03-13 | Huvepharma Eood | New thermostable phytases with high catalytic efficacy |
CN109601822B (zh) * | 2019-01-22 | 2022-11-08 | 北京三强核力辐射工程技术有限公司 | 一种生物碱协同辐照降解动物源性食品中抗生素的方法 |
CN110029120B (zh) * | 2019-03-19 | 2022-03-01 | 青岛蔚蓝生物集团有限公司 | 一种植酸酶高产菌株及其应用 |
CN112680464B (zh) * | 2020-12-10 | 2022-04-26 | 南京农业大学 | 一种单甲基砷和三价锑氧化酶基因arsV及其编码的蛋白和应用 |
Family Cites Families (120)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA940070A (en) | 1968-12-23 | 1974-01-15 | Jim S. Berry | Stabilized aqueous enzyme composition |
US3860484A (en) | 1972-09-28 | 1975-01-14 | Xerox Corp | Enzyme stabilization |
DE2426988C2 (de) | 1974-06-04 | 1985-02-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Trägerbindung biologisch aktiver Proteine |
US3966971A (en) | 1975-01-02 | 1976-06-29 | Grain Processing Corporation | Separation of protein from vegetable sources |
DE2931999A1 (de) | 1979-08-03 | 1981-02-26 | Schering Ag | Herstellung und anwendung von neukombinierten plasmiden mit genen fuer alkalische phosphatasen |
DE3126759A1 (de) | 1981-07-07 | 1983-01-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung |
JPS5931799A (ja) | 1982-08-16 | 1984-02-20 | Science & Tech Agency | B型肝炎ウイルス遺伝子を組込んだ組換えプラスミド |
US4470968A (en) | 1983-01-13 | 1984-09-11 | Miles Laboratories, Inc. | Pasteurized therapeutically active blood coagulation factor concentrates |
SE450325B (sv) | 1983-02-23 | 1987-06-22 | Tricum Ab | Kostfiberprodukt baserad pa skaldelar fran froet hos ceralier |
AR245671A1 (es) | 1984-08-15 | 1994-02-28 | American Safety Closure | Perfeccionamientos en tapones de material plastico a prueba de manipulaciones indebidas. |
SE465951B (sv) | 1984-10-23 | 1991-11-25 | Perstorp Ab | Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav |
DE3515586A1 (de) | 1985-04-30 | 1986-11-06 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisiertes sarcosinoxidase-praeparat |
US5024941A (en) * | 1985-12-18 | 1991-06-18 | Biotechnica International, Inc. | Expression and secretion vector for yeast containing a glucoamylase signal sequence |
JPH0655146B2 (ja) | 1985-12-27 | 1994-07-27 | 財団法人化学及血清療法研究所 | シヤトルベクタ− |
US5780292A (en) | 1987-04-29 | 1998-07-14 | Alko Group Ltd. | Production of phytate degrading enzymes in trichoderma |
NL8702735A (nl) | 1987-11-17 | 1989-06-16 | Dorr Oliver Inc | Werkwijze voor het weken van granen met een nieuw enzympreparaat. |
JPH04501662A (ja) * | 1988-09-26 | 1992-03-26 | ザ・サルク・インスティチュート・バイオテクノロジー/インダストリアル・アソシエイツ・インコーポレーテッド | 混合給送組換え酵母発酵 |
GB8826429D0 (en) | 1988-11-11 | 1988-12-14 | Univ Leeds Ind Service Ltd | Enzyme stabilisation systems |
US5316770A (en) | 1989-02-16 | 1994-05-31 | University Of Georgia Research Foundation, Inc. | Vitamin D derivative feed compositions and methods of use |
US5366736A (en) | 1989-02-16 | 1994-11-22 | University Of Georgia Research Foundation, Inc. | Vitamin D derivative feed compositions and methods of use |
CZ289014B6 (cs) * | 1989-09-27 | 2001-10-17 | Dsm N. V. | Vyčiątěná a izolovaná sekvence DNA kódující fungální fytázu, konstrukt pro expresi, vektory a transformované hostitelské buňky a způsob produkce fytázy |
UA27702C2 (uk) | 1989-09-27 | 2000-10-16 | Гіст-Брокейдс Н.В. | Фрагмент геномної днк, що кодує фітазу aspergillus niger,фрагмент кднк, що кодує фітазу aspergillus niger, рекомбінантна плазмідна днк для експресії фітази в aspergillus (варіанти), штам aspergillus-продуцент фітази aspergillus (варіанти), спосіб одержання фітази, рекомбінанта фітаза aspergillus niger |
IL97645A (en) | 1990-03-23 | 1997-03-18 | Gist Brocades Nv | Production of enzymes in seeds and their use |
US5593963A (en) | 1990-09-21 | 1997-01-14 | Mogen International | Expression of phytase in plants |
KR100225087B1 (ko) | 1990-03-23 | 1999-10-15 | 한스 발터라벤 | 피타아제의 식물내 발현 |
GB9006642D0 (en) | 1990-03-24 | 1990-05-23 | Gibson Timothy D | Enzyme stabilisation |
DE4011084A1 (de) | 1990-04-05 | 1991-10-10 | Boehringer Mannheim Gmbh | Saccharid-modifizierte, wasserloesliche proteine |
US5200399A (en) | 1990-09-14 | 1993-04-06 | Boyce Thompson Institute For Plant Research, Inc. | Method of protecting biological materials from destructive reactions in the dry state |
EP0513332A4 (en) | 1990-11-14 | 1993-03-17 | Cargill, Incorporated | Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins |
US5268273A (en) | 1990-12-14 | 1993-12-07 | Phillips Petroleum Company | Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same |
DE4119281A1 (de) | 1991-06-12 | 1992-12-17 | Basf Ag | Verfahren zur herstellung von enzymzubereitungen |
DE69319758T2 (de) | 1992-01-24 | 1998-11-26 | Gist Brocades Nv | Verfahren zur Herstellung von Futterpellets |
IL104704A0 (en) | 1992-02-13 | 1993-06-10 | Gist Brocades Nv | Stabilized aqueous liquid formulation of phytase |
US5216770A (en) * | 1992-03-11 | 1993-06-08 | Holt William J | Support device |
PT655890E (pt) | 1992-07-31 | 2005-05-31 | Ab Enzymes Gmbh | Celulas recombinantes, construcoes de adn, vectores e metodos para expressao de enzimas degradantes de fitato em proporcoes desejadas |
ES2202305T3 (es) | 1993-04-05 | 2004-04-01 | Aveve N.V. | Hidrolisis de fitina y composicion de enzimas que tienen actividad hidrolizante de fitato. |
JP2696057B2 (ja) | 1993-05-11 | 1998-01-14 | ニチモウ株式会社 | 穀類を原料とした生成物の製造方法 |
DK82893D0 (da) | 1993-07-08 | 1993-07-08 | Novo Nordisk As | Peptid |
FR2715802B1 (fr) | 1994-02-04 | 1996-03-15 | Rhone Poulenc Nutrition Animal | Utilisation d'enzymes dans l'alimentation des animaux pour réduire les rejets azotés. |
US5955448A (en) | 1994-08-19 | 1999-09-21 | Quadrant Holdings Cambridge Limited | Method for stabilization of biological substances during drying and subsequent storage and compositions thereof |
JP3678310B2 (ja) | 1994-04-22 | 2005-08-03 | ノボザイムス アクティーゼルスカブ | 植物性タンパク質の溶解度を改善する方法 |
US6291221B1 (en) | 1994-04-25 | 2001-09-18 | Roche Vitamins Inc. | Heat tolerant phytases |
DE69535097T2 (de) | 1994-04-25 | 2006-12-28 | Dsm Ip Assets B.V. | Polypeptide mit phytase Wirkung |
US5830732A (en) | 1994-07-05 | 1998-11-03 | Mitsui Toatsu Chemicals, Inc. | Phytase |
GB9416841D0 (en) | 1994-08-19 | 1994-10-12 | Finnfeeds Int Ltd | An enzyme feed additive and animal feed including it |
FR2729971B1 (fr) | 1995-01-31 | 1997-06-06 | Roquette Freres | Composition nutritive resultant de la trempe du mais et son procede d'obtention |
US5935624A (en) | 1995-02-06 | 1999-08-10 | Wisconsin Alumni Research Foundation | Low phosphorus animal feed containing 1α-hydroxylated vitamin D compounds and method of preparing |
US5556771A (en) | 1995-02-10 | 1996-09-17 | Gen-Probe Incorporated | Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification |
ATE268817T1 (de) | 1995-07-28 | 2004-06-15 | Basf Ag | Salz-stabilisierte enzymzubereitung |
EP0858266A1 (en) | 1995-11-02 | 1998-08-19 | Novo Nordisk A/S | Feed enzyme preparations |
DK172530B1 (da) | 1995-11-10 | 1998-11-23 | Leo Pharm Prod Ltd | Tilsætningsprodukt til drikkevand og foder til dyr samt fremgangsmåde for tilsætning |
US5830696A (en) | 1996-12-05 | 1998-11-03 | Diversa Corporation | Directed evolution of thermophilic enzymes |
WO1997035016A1 (en) | 1996-03-18 | 1997-09-25 | Novo Nordisk Biotech Inc | Polypeptides having phytase activity and nucleic acids encoding same |
EA199800891A1 (ru) | 1996-04-05 | 1999-04-29 | Киова Хакко Когио Ко., Лтд | Новая фитаза и ген, кодирующий указанную фитазу |
CN1216446A (zh) | 1996-04-23 | 1999-05-12 | 诺沃挪第克公司 | 动物饲料添加剂 |
US5900525A (en) | 1996-04-26 | 1999-05-04 | Wisconsin Alumni Research Foundation | Animal feed compositions containing phytase derived from transgenic alfalfa and methods of use thereof |
EP1015826A2 (en) | 1996-05-29 | 2000-07-05 | Universal Preservation Technologies, Inc. | Long-term shelf preservation by vitrification |
US5985605A (en) | 1996-06-14 | 1999-11-16 | Her Majesty The Queen In Right Of Canada, As Represented By The Dept. Of Agriculture & Agri-Food Canada | DNA sequences encoding phytases of ruminal microorganisms |
AU3494397A (en) | 1996-06-18 | 1998-01-07 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Fibroblast growth factor receptor activating gene i and related compositions and methods |
FR2751333B1 (fr) | 1996-07-18 | 1998-09-25 | Roquette Freres | Composition nutritive amelioree resultant de la trempe du mais et son procede d'obtention |
FR2751987B1 (fr) | 1996-08-01 | 1998-12-31 | Biocem | Phytases de plantes et applications biotechnologiques |
GB2316082A (en) * | 1996-08-13 | 1998-02-18 | Finnfeeds Int Ltd | Phytase |
SE507355C2 (sv) | 1996-09-18 | 1998-05-18 | Semper Ab | Förfarande för reducering av halten fytat i korn av spannmål |
WO1998013480A1 (fr) | 1996-09-25 | 1998-04-02 | Kyowa Hakko Kogyo Co., Ltd. | Nouvelle phytase et son procede de preparation |
GB2319030A (en) | 1996-11-05 | 1998-05-13 | Finnfeeds Int Ltd | Phytase extracted from soybean |
US6039942A (en) | 1996-12-20 | 2000-03-21 | Novo Nordick A/S | Phytase polypeptides |
WO1998030681A1 (en) | 1997-01-09 | 1998-07-16 | Novo Nordisk A/S | Phytase combinations |
KR100222638B1 (ko) | 1997-01-20 | 1999-10-01 | 배희동 | 종자를 이용한 효소산물 및 사료원료의 생산 |
JPH10224186A (ja) | 1997-02-07 | 1998-08-21 | Oki Electric Ind Co Ltd | 電圧制御発振器 |
CA2231948C (en) | 1997-03-25 | 2010-05-18 | F. Hoffmann-La Roche Ag | Modified phytases |
KR100206453B1 (ko) | 1997-03-27 | 1999-07-01 | 박원훈 | 신규한플라즈미드를이용하여형질전환시킨균주 이.채씨오엘아이.피와이로부터생산된피타제 |
WO1998054305A1 (en) | 1997-05-28 | 1998-12-03 | Primary Applications Pty. Limited | Enhancement of industrial enzymes |
ATE266721T1 (de) | 1997-06-04 | 2004-05-15 | Basf Ag | Hochaktive phytasen enthaltende granulat |
NZ330940A (en) | 1997-07-24 | 2000-02-28 | F | Production of consensus phytases from fungal origin using computer programmes |
US7432097B2 (en) | 1997-08-13 | 2008-10-07 | Verenium Corporation | Phytases, nucleic acids encoding them and methods of making and using them |
US5876997A (en) | 1997-08-13 | 1999-03-02 | Diversa Corporation | Phytase |
US6855365B2 (en) | 1997-08-13 | 2005-02-15 | Diversa Corporation | Recombinant bacterial phytases and uses thereof |
US7078035B2 (en) * | 1997-08-13 | 2006-07-18 | Diversa Corporation | Phytases, nucleic acids encoding them and methods for making and using them |
US6720014B1 (en) | 1997-08-13 | 2004-04-13 | Diversa Corporation | Phytase-containing foodstuffs and methods of making and using them |
US6183740B1 (en) | 1997-08-13 | 2001-02-06 | Diversa Corporation | Recombinant bacterial phytases and uses thereof |
US6022555A (en) | 1997-09-05 | 2000-02-08 | Wisconsin Alumni Research Foundation | Animal feed containing carboxylic acids |
DK0911416T3 (da) | 1997-10-01 | 2006-08-14 | Dsm Ip Assets Bv | Fremgangsmåde til fremstilling af protein |
DE19743683A1 (de) | 1997-10-02 | 1999-04-08 | Basf Ag | Verfahren zur Änderung der Substratspezifität von Enzymen |
DE69720478T2 (de) | 1997-12-23 | 2003-12-18 | Cargill Bv | Proteine enthaltendes Futtermittel und Verfahren zur Herstellung |
US20010018197A1 (en) | 1997-12-23 | 2001-08-30 | Protein Technologies International, Inc. | Method for producing ultrapure vegetable protein materials |
CN1192103C (zh) | 1998-01-27 | 2005-03-09 | 三井化学株式会社 | 生产植酸酶的方法 |
US6514495B1 (en) | 1998-03-23 | 2003-02-04 | Novozymes A/S | Phytase varinats |
WO1999049022A1 (en) | 1998-03-23 | 1999-09-30 | Novo Nordisk A/S | Phytase variants |
KR20010042395A (ko) | 1998-04-01 | 2001-05-25 | 윌리암 로엘프 드 보에르 | 저 함량의 피테이트를 가지는 사료에서 피타제의 사용 |
US6451572B1 (en) * | 1998-06-25 | 2002-09-17 | Cornell Research Foundation, Inc. | Overexpression of phytase genes in yeast systems |
GB2340727B (en) | 1998-08-19 | 2002-05-22 | Univ Saskatchewan | Process for converting phytate into inorganic phosphate |
US6284502B1 (en) | 1998-08-21 | 2001-09-04 | University Of Saskatchewan | Process for converting phytate into inorganic phosphate |
BR9914217A (pt) | 1998-10-02 | 2001-07-03 | Novozymes As | Composição de fitase sólida, processo para preparar a mesma, e, composição sólida |
EP1144438A3 (en) | 1999-01-14 | 2002-02-27 | Novozymes Biotech, Inc. | Polypeptides having acid phosphatase activity and nucleic acids encoding same |
BR0007655A (pt) | 1999-01-22 | 2001-11-06 | Novozymes As | Fitase, sequência de dna, vetor, célula hospedeira microbiana, processo para produzir uma fitase, e, alimento, gênero alimentìcio ou composição farmacêutica |
US6720174B1 (en) | 1999-01-28 | 2004-04-13 | Novozymes A/S | Phytases |
BR0004713A (pt) | 1999-02-10 | 2000-12-19 | Dsm Nv | Granulados contendo enzimas de alimentação |
EP1165806B1 (en) | 1999-03-31 | 2005-08-03 | Cornell Research Foundation, Inc. | Phosphatases with improved phytase activity |
EP1187538B1 (en) | 1999-05-31 | 2006-05-24 | Société des Produits Nestlé S.A. | Cereal products having low phytic acid content |
DE60043443D1 (de) | 1999-08-13 | 2010-01-14 | Inst Of Grassland And Environm | Phytase enzyme, dafür kodierende nukleinsäuren, und solche enthaltende vectoren und wirtszellen |
DK1092764T3 (da) | 1999-10-11 | 2010-04-26 | Dsm Ip Assets Bv | Kontinuerlig fermentering |
US6509432B2 (en) * | 1999-10-25 | 2003-01-21 | Kansai Paint Co., Ltd. | Ordinary temperature curable coating composition |
AU1618801A (en) | 1999-11-18 | 2001-05-30 | Cornell Research Foundation Inc. | Site-directed mutagenesis of escherichia coli phytase |
US6841370B1 (en) | 1999-11-18 | 2005-01-11 | Cornell Research Foundation, Inc. | Site-directed mutagenesis of Escherichia coli phytase |
FR2804691B1 (fr) | 2000-02-04 | 2003-11-07 | Roquette Freres | Composition azotee resultant de l'hydrolyse du gluten de mais et son procede de fabrication |
AU781415B2 (en) | 2000-02-08 | 2005-05-19 | Dsm Ip Assets B.V. | Use of acid-stable proteases in animal feed |
CA2411230A1 (en) | 2000-05-25 | 2001-11-29 | Diversa Corporation | Dietary aids and methods of use thereof |
US20030101476A1 (en) | 2000-12-12 | 2003-05-29 | Short Jay M. | Recombinant phytases and uses thereof |
WO2003037102A2 (en) | 2001-10-31 | 2003-05-08 | Phytex, Llc | Phytase-containing animal food and method |
TWI262083B (en) | 2001-12-28 | 2006-09-21 | Syngenta Participations Ag | Microbially-expressed thermotolerant phytase for animal feed |
JP3970811B2 (ja) * | 2002-09-09 | 2007-09-05 | 独立行政法人科学技術振興機構 | リンカー化合物及びリガンド、並びにそれらの製造方法 |
EP1604008B1 (en) * | 2002-09-13 | 2010-12-22 | Cornell Research Foundation, Inc. | Using mutations to improve aspergillus phytases |
US7658922B2 (en) | 2005-06-24 | 2010-02-09 | Ab Enzymes Gmbh | Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase |
US7919297B2 (en) * | 2006-02-21 | 2011-04-05 | Cornell Research Foundation, Inc. | Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase |
JP5221516B2 (ja) | 2006-04-04 | 2013-06-26 | ノボザイムス アクティーゼルスカブ | フィターゼ変異体 |
WO2008017066A2 (en) * | 2006-08-03 | 2008-02-07 | Cornell Research Foundation, Inc. | Phytases with improved thermal stability |
US8192734B2 (en) * | 2007-07-09 | 2012-06-05 | Cornell University | Compositions and methods for bone strengthening |
US20090074994A1 (en) * | 2007-09-14 | 2009-03-19 | Mclean Linda L | Kit for Decorating A Car |
GB0922467D0 (en) | 2009-04-24 | 2010-02-03 | Danisco | Feed supplement |
US8334124B1 (en) | 2009-09-23 | 2012-12-18 | The United States Of America As Represented By The Secretary Of Agriculture | Modified Aspergillus niger phytase |
-
1998
- 1998-06-25 US US09/104,769 patent/US6451572B1/en not_active Expired - Lifetime
-
1999
- 1999-06-23 CN CNB998098930A patent/CN100365126C/zh not_active Expired - Lifetime
- 1999-06-23 EP EP99935340.2A patent/EP1090129B2/en not_active Expired - Lifetime
- 1999-06-23 ES ES06075318.3T patent/ES2560661T3/es not_active Expired - Lifetime
- 1999-06-23 AU AU50837/99A patent/AU772071B2/en not_active Expired
- 1999-06-23 EP EP15200497.4A patent/EP3020815A1/en not_active Withdrawn
- 1999-06-23 PL PL99345408A patent/PL345408A1/xx unknown
- 1999-06-23 HU HU0102800A patent/HUP0102800A2/hu unknown
- 1999-06-23 BR BRPI9911549A patent/BRPI9911549B1/pt active IP Right Grant
- 1999-06-23 KR KR1020007014601A patent/KR100870886B1/ko not_active IP Right Cessation
- 1999-06-23 JP JP2000556038A patent/JP2002518052A/ja not_active Withdrawn
- 1999-06-23 AT AT99935340T patent/ATE317904T1/de not_active IP Right Cessation
- 1999-06-23 CA CA2332180A patent/CA2332180C/en not_active Expired - Lifetime
- 1999-06-23 PT PT60753183T patent/PT1688500E/pt unknown
- 1999-06-23 ES ES99935340T patent/ES2255281T5/es not_active Expired - Lifetime
- 1999-06-23 CZ CZ20004805A patent/CZ301680B6/cs not_active IP Right Cessation
- 1999-06-23 WO PCT/US1999/014106 patent/WO1999067398A2/en active IP Right Grant
- 1999-06-23 DE DE69929886.5T patent/DE69929886C5/de not_active Expired - Lifetime
- 1999-06-23 MX MXPA00012794 patent/MX258391B/es active IP Right Grant
- 1999-06-23 EP EP06075318.3A patent/EP1688500B1/en not_active Revoked
- 1999-06-23 DK DK06075318.3T patent/DK1688500T3/en active
- 1999-06-23 DK DK99935340.2T patent/DK1090129T4/da active
-
2002
- 2002-03-08 US US10/094,693 patent/US7026150B2/en not_active Expired - Lifetime
-
2006
- 2006-03-10 US US11/372,851 patent/US7312063B2/en not_active Expired - Fee Related
-
2007
- 2007-12-21 US US11/962,446 patent/US7829318B2/en not_active Expired - Fee Related
-
2009
- 2009-10-22 JP JP2009243724A patent/JP2010046085A/ja active Pending
-
2010
- 2010-11-08 US US12/941,445 patent/US8455232B2/en not_active Expired - Lifetime
-
2013
- 2013-05-17 US US13/897,172 patent/US8993300B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9911549A (pt) | Processo de produção de fitase em levedura | |
ATE290086T1 (de) | Herstellung von phytat-degradierenden enzymen in trichoderma | |
BR9609791A (pt) | Processo para estabilizar proteínas em um meio ácido com um pectina de elevado teor em éster | |
BG104149A (en) | Interleukin-18-binding proteins, methods for their preparation and administration | |
ES2056817T5 (es) | Transformacion de trichoderma. | |
AR020735A1 (es) | Un procedimiento para la obtencion de un polipeptido glucosilado a partir de celulas eucarioticas | |
ATE212059T1 (de) | Methoden zur identifizierung heterofunktionaler fusionsproteine | |
WO1999025878A3 (en) | Methods for modulating and identifying cellular senescence | |
DE69837475D1 (de) | Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren | |
WO1994021800A3 (en) | Protein tyrosine phosphatase ptp-s31 | |
ATE281528T1 (de) | Rekombinante ribonuklease proteine | |
AU8209187A (en) | Hybrid proteins | |
PL342578A1 (en) | Deep-frozen article of food | |
PT635025E (pt) | Processo para preparar proteinas modificadas | |
ES2149244T3 (es) | Procedimientos para producir proteina c. | |
AUPM772494A0 (en) | Improvements in production of proteins in host cells | |
KR890008166A (ko) | 융합 단백질의 선택적 분해 방법 | |
ATE346941T1 (de) | Protein-disulfidisomerase-gen eines methylotrophen hefestammes | |
WO1995021916A3 (en) | Pp32: a newly identified cd45-associated protein | |
BR9912106A (pt) | Vetor de expressão de levedura recombinante, processo para fazer um polipeptìdeo ou proteìna desejados, e, célula de levedura transformada | |
ATE282701T1 (de) | Rekombinante dnase b aus streptococcus pyogenes | |
EP0326799A3 (de) | Verfahren zur enzymatischen Peptidsynthese | |
YU47990A (sh) | Sekvenca cdna za ovčji preprokimozin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10O(IX), 11, 13 E 25 DA LPI. |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/08/2016, OBSERVADAS AS CONDICOES LEGAIS. |