BR9814353A - Colìrio hidrosolúvel com tempo longo de duração da eficácia da droga - Google Patents

Colìrio hidrosolúvel com tempo longo de duração da eficácia da droga

Info

Publication number
BR9814353A
BR9814353A BR9814353-0A BR9814353A BR9814353A BR 9814353 A BR9814353 A BR 9814353A BR 9814353 A BR9814353 A BR 9814353A BR 9814353 A BR9814353 A BR 9814353A
Authority
BR
Brazil
Prior art keywords
water
soluble
long
eye drops
drug effectiveness
Prior art date
Application number
BR9814353-0A
Other languages
English (en)
Inventor
Yuji Sugahara
Kazuya Sakata
Masaaki Odomi
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BR9814353A publication Critical patent/BR9814353A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

<B>COLìRIO HIDROSOLúVEL COM TEMPO LONGO DE DURAçãO DA EFICáCIA DA DROGA<D> A descoberta é um colírio hidrosolúvel compreendendo (a) pelo menos um selecionando do carteolol e um sal ácido de adição ácida deste, (b) pelo menos um polímero acrílico selecionado de um ácido poliacrílico do tipo cadeia reta e um sal hidrosolúvel farmaceuticamente aceitável deste, e (c) pelo menos um selecionado de um sal metálico alcalino hidrosolúvel e uma amina hidrosolúvel. O colírio hidrosolúvel da presente invenção tem um tempo de duração da eficácia da droga consideravelmente longo, e é superior na ação inibitória sobre a pressão intra-ocular e é efetivo para o tratamento do glaucoma.
BR9814353-0A 1997-12-22 1998-12-16 Colìrio hidrosolúvel com tempo longo de duração da eficácia da droga BR9814353A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP35303997 1997-12-22
JP29855098 1998-10-20
PCT/JP1998/005699 WO1999032087A1 (en) 1997-12-22 1998-12-16 Water-soluble eye drop

Publications (1)

Publication Number Publication Date
BR9814353A true BR9814353A (pt) 2000-10-03

Family

ID=26561565

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814353-0A BR9814353A (pt) 1997-12-22 1998-12-16 Colìrio hidrosolúvel com tempo longo de duração da eficácia da droga

Country Status (19)

Country Link
US (1) US6303631B1 (pt)
EP (1) EP1054662B1 (pt)
JP (1) JP2000191534A (pt)
KR (1) KR100350824B1 (pt)
CN (1) CN1137679C (pt)
AR (1) AR017939A1 (pt)
AT (1) ATE266386T1 (pt)
AU (1) AU740756B2 (pt)
BR (1) BR9814353A (pt)
CA (1) CA2315818C (pt)
DE (1) DE69823879T2 (pt)
DK (1) DK1054662T3 (pt)
ES (1) ES2218873T3 (pt)
HK (1) HK1033437A1 (pt)
ID (1) ID25544A (pt)
MY (1) MY116782A (pt)
PT (1) PT1054662E (pt)
TW (1) TW520296B (pt)
WO (1) WO1999032087A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423526B1 (en) * 1999-11-23 2002-07-23 Zymogenetics, Inc. Human serine protease
BR0109317A (pt) * 2000-07-14 2003-06-17 Allergan Inc Composições contendo componentes agonistas alfa-2-adrenérgicos
JP2002154989A (ja) * 2000-11-14 2002-05-28 Lion Corp 眼科用組成物、及び生体粘膜への薬物の滞留性向上組成物
CA2446705C (en) * 2001-05-03 2012-03-06 David F. Woodward Compositions of quinoxaline-based therapeutic agents and fatty acids having enhanced pharmacokinetic characteristics
JP3974117B2 (ja) 2004-03-23 2007-09-12 理想科学工業株式会社 孔版印刷用インキ
JP5403850B2 (ja) * 2004-06-08 2014-01-29 ロート製薬株式会社 眼科用清涼組成物
US7758553B2 (en) * 2006-04-03 2010-07-20 Insight Vision Incorporated Drop dispenser for the delivery of uniform droplets of viscous liquids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056684B2 (ja) 1977-11-07 1985-12-11 東興薬品工業株式会社 点眼剤
AU518814B2 (en) 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
US5461081A (en) 1989-09-28 1995-10-24 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
SE512871C2 (sv) 1992-08-20 2000-05-29 Santen Oy Oftalmologisk beredning innehållande pilokarpin och ytterligare medel för behandling av okular hypertension
SE9401109D0 (sv) 1994-03-31 1994-03-31 Leiras Oy Opthalmic composition II

Also Published As

Publication number Publication date
WO1999032087A1 (en) 1999-07-01
CA2315818A1 (en) 1999-07-01
MY116782A (en) 2004-03-31
CN1283105A (zh) 2001-02-07
US6303631B1 (en) 2001-10-16
AU1682799A (en) 1999-07-12
EP1054662A1 (en) 2000-11-29
JP2000191534A (ja) 2000-07-11
CN1137679C (zh) 2004-02-11
AR017939A1 (es) 2001-10-24
ES2218873T3 (es) 2004-11-16
ATE266386T1 (de) 2004-05-15
HK1033437A1 (en) 2001-08-31
EP1054662B1 (en) 2004-05-12
DE69823879D1 (de) 2004-06-17
DE69823879T2 (de) 2005-03-24
AU740756B2 (en) 2001-11-15
ID25544A (id) 2000-10-12
CA2315818C (en) 2005-10-11
TW520296B (en) 2003-02-11
PT1054662E (pt) 2004-07-30
DK1054662T3 (da) 2004-07-19
KR100350824B1 (ko) 2002-08-29
KR20010024797A (ko) 2001-03-26

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DE INT.CL.8: A61K 47/32, A61K 31/4704, A61K 9/08, A61K 47/02, A61K 47/18, A61P 27/06

Ipc: A61K 47/32 (2007.10), A61K 31/4704 (2007.10), A61K

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE ESTE NAO POSSUI ATIVIDADE INVENTIVA, CONTRARIANDO O DISPOSTO NOS ARTIGOS 8O E 13 DA LPI

B12B Appeal against refusal [chapter 12.2 patent gazette]