BR112018077188A2 - frutose-6-fosfato-3-epimerase termoestável inovadora e um método para produzir alulose com o uso da mesma - Google Patents

frutose-6-fosfato-3-epimerase termoestável inovadora e um método para produzir alulose com o uso da mesma

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Publication number
BR112018077188A2
BR112018077188A2 BR112018077188A BR112018077188A BR112018077188A2 BR 112018077188 A2 BR112018077188 A2 BR 112018077188A2 BR 112018077188 A BR112018077188 A BR 112018077188A BR 112018077188 A BR112018077188 A BR 112018077188A BR 112018077188 A2 BR112018077188 A2 BR 112018077188A2
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BR
Brazil
Prior art keywords
phosphate
epimerase
fructose
innovative
alulose
Prior art date
Application number
BR112018077188A
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English (en)
Other versions
BR112018077188B1 (pt
Inventor
Kug Cho Hyun
Bo Kim Seong
Jun Cho Seong
Yang Sungjae
Mi Lee Young
Original Assignee
Cj Cheiljedang Corp
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60787012&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112018077188(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of BR112018077188A2 publication Critical patent/BR112018077188A2/pt
Publication of BR112018077188B1 publication Critical patent/BR112018077188B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/03—Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01063—Polyphosphate--glucose phosphotransferase (2.7.1.63)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/02—Phosphotransferases (phosphomutases) (5.4.2)
    • C12Y504/02002—Phosphoglucomutase (5.4.2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

a presente revelação refere-se a frutose-6-fosfato-3-epimerase que consiste em uma sequência de aminoácidos de seq id no: 1, um ácido nucleico que codifica a frutose-6-fosfato-3-epimerase, e um transformante que compreende o ácido nucleico. adicionalmente, a presente revelação se refere a uma composição para produzir alulose, que compreende a frutose-6-fosfato-3-epimerase da presente revelação, e um método para produzir alulose com o uso da frutose-6-fosfato-3-epimerase da presente revelação.
BR112018077188-0A 2016-06-30 2017-06-30 Método e composição compreendendo frutose-6-fosfato-3-epimerase termoestável para produzir alulose BR112018077188B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20160082543 2016-06-30
KR10-2016-0082543 2016-06-30
PCT/KR2017/006985 WO2018004308A2 (ko) 2016-06-30 2017-06-30 신규 내열성 과당-6-인산-3-에피머화 효소 및 이를 이용한 알룰로스 제조방법

Publications (2)

Publication Number Publication Date
BR112018077188A2 true BR112018077188A2 (pt) 2019-06-25
BR112018077188B1 BR112018077188B1 (pt) 2022-09-06

Family

ID=60787012

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018077188-0A BR112018077188B1 (pt) 2016-06-30 2017-06-30 Método e composição compreendendo frutose-6-fosfato-3-epimerase termoestável para produzir alulose

Country Status (13)

Country Link
US (1) US10907182B2 (pt)
EP (1) EP3480306B1 (pt)
JP (1) JP6817343B2 (pt)
KR (2) KR101966530B1 (pt)
CN (1) CN109563499B (pt)
AU (1) AU2017287764B2 (pt)
BR (1) BR112018077188B1 (pt)
CA (1) CA3027687C (pt)
ES (1) ES2950576T3 (pt)
MX (1) MX2018016114A (pt)
PL (1) PL3480306T3 (pt)
RU (1) RU2733427C2 (pt)
WO (1) WO2018004308A2 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018016114A (es) * 2016-06-30 2019-10-14 Cj Cheiljedang Corp Una novedosa fructosa-6-fosfato-3-epimerasa termoestable y un procedimiento para producir alulosa mediante el uso de la misma.
AU2017376628B2 (en) * 2016-12-14 2021-04-29 Bonumose, Inc. Enzymatic production of D-allulose
CN108251468A (zh) * 2018-02-06 2018-07-06 南京朗奈生物技术有限公司 生物法生产d-阿洛酮糖的工艺
KR102233375B1 (ko) * 2018-12-11 2021-03-31 씨제이제일제당 주식회사 신규 싸이코스-6-인산의 탈인산화 효소, 이를 포함하는 싸이코스 생산용 조성물, 및 이를 이용한 싸이코스 제조방법
KR102138862B1 (ko) * 2019-03-08 2020-07-30 씨제이제일제당 주식회사 알룰로스를 생산하는 스태필로코커스 속 미생물 및 이를 이용한 알룰로스 제조방법
KR102256624B1 (ko) * 2019-03-19 2021-05-26 주식회사 삼양사 인산화당 에피머 효소
KR102080886B1 (ko) * 2019-05-21 2020-02-24 씨제이제일제당 주식회사 부반응성이 낮은 리불로스-인산 3-에피머화 효소의 모티프 및 이를 포함하는 효소
KR20220016201A (ko) * 2019-05-31 2022-02-08 보너모스, 인코포레이티드 프룩토스의 효소적 생산
WO2021086010A1 (ko) * 2019-10-28 2021-05-06 주식회사 삼양사 과당-6-인산 3-에피머화 효소 및 이의 용도
CN114729345A (zh) * 2019-10-28 2022-07-08 株式会社三养社 果糖6-磷酸3-差向异构酶及其用途
KR102509561B1 (ko) * 2020-12-21 2023-03-14 주식회사 삼양사 높은 기질 특이성을 갖는 탈인산화 효소 단백질 및 이의 용도
CN114790469B (zh) * 2021-01-26 2024-03-26 中国科学院天津工业生物技术研究所 一种酶促合成阿洛酮糖的方法

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
DE10037611A1 (de) * 2000-08-02 2002-02-14 Degussa Neue für das rpe-Gen kodierende Nuleotidsequenzen
KR100744479B1 (ko) 2005-06-01 2007-08-01 씨제이 주식회사 사이코스 에피머화 효소에 의한 사이코스의 생산 방법
CN100577793C (zh) * 2007-12-12 2010-01-06 江南大学 微生物转化d-果糖制备d-阿洛酮糖的菌种和方法
GB0822937D0 (en) * 2008-12-16 2009-01-21 Terranol As Microorganism
CN102382867A (zh) 2010-09-06 2012-03-21 黄卫东 一种胞外酶催化糖合成方法
KR20140080282A (ko) 2012-12-20 2014-06-30 주식회사 삼양제넥스 Ｄ-사이코스 3-에피머화 효소를 이용한 과당으로부터 사이코스의 제조방법
KR101610911B1 (ko) 2013-05-09 2016-04-08 주식회사 삼양사 L-리불로스 5-인산 4-에피머화 효소를 이용한 과당에서 타가토스 생산
KR102189458B1 (ko) * 2013-09-03 2020-12-11 로께뜨프레르 D-사이코스 3-에피머라제의 개선된 변이체 및 그의 용도
US10480018B2 (en) 2015-05-22 2019-11-19 Archer Daniels Midland Company Genus of epimerase enzymes for conversion of fructose to allulose at high temperature and low pH
MX2018016114A (es) 2016-06-30 2019-10-14 Cj Cheiljedang Corp Una novedosa fructosa-6-fosfato-3-epimerasa termoestable y un procedimiento para producir alulosa mediante el uso de la misma.

Also Published As

Publication number Publication date
JP6817343B2 (ja) 2021-01-20
RU2019100788A3 (pt) 2020-07-30
BR112018077188B1 (pt) 2022-09-06
EP3480306B1 (en) 2023-06-07
RU2019100788A (ru) 2020-07-30
AU2017287764B2 (en) 2021-01-21
KR20180004023A (ko) 2018-01-10
KR101966530B1 (ko) 2019-04-08
EP3480306A4 (en) 2020-03-11
WO2018004308A3 (ko) 2018-02-22
AU2017287764A1 (en) 2018-12-20
MX2018016114A (es) 2019-10-14
ES2950576T3 (es) 2023-10-11
RU2733427C2 (ru) 2020-10-01
CN109563499A (zh) 2019-04-02
PL3480306T3 (pl) 2023-11-06
CA3027687A1 (en) 2018-01-04
KR102042044B1 (ko) 2019-12-02
KR20190038775A (ko) 2019-04-09
US20190225997A1 (en) 2019-07-25
WO2018004308A2 (ko) 2018-01-04
US10907182B2 (en) 2021-02-02
CA3027687C (en) 2022-07-05
EP3480306A2 (en) 2019-05-08
CN109563499B (zh) 2022-08-12
JP2019522477A (ja) 2019-08-15

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Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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