BR112015003041A2 - Intermediário para síntese de 1-(2-desóxi-2-fluoro-4 -tio-\beta-d-arabinofuranosil)citosina , intermediário para síntese de tionucleosídeo , e métodos para produzir estes intermediários - Google Patents

Intermediário para síntese de 1-(2-desóxi-2-fluoro-4 -tio-\beta-d-arabinofuranosil)citosina , intermediário para síntese de tionucleosídeo , e métodos para produzir estes intermediários

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Publication number
BR112015003041A2
BR112015003041A2 BR112015003041-6A BR112015003041A BR112015003041A2 BR 112015003041 A2 BR112015003041 A2 BR 112015003041A2 BR 112015003041 A BR112015003041 A BR 112015003041A BR 112015003041 A2 BR112015003041 A2 BR 112015003041A2
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BR
Brazil
Prior art keywords
synthesis
dexyx
arabinofuranosil
thionucleoside
intermediaries
Prior art date
Application number
BR112015003041-6A
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English (en)
Japanese (ja)
Other versions
BR112015003041B1 (pt
Inventor
Nakamura Kouki
Shimamura Satoshi
Imoto Junichi
Takahashi Motomasa
Watanabe Katsuyuki
Wada Kenji
Fujino Yuuta
Matsumoto Takuya
Takahashi Makoto
Okada Hideki
Yamane Takehiro
Ito Takayuki
Original Assignee
Fujifilm Corporation
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Publication date
Application filed by Fujifilm Corporation filed Critical Fujifilm Corporation
Publication of BR112015003041A2 publication Critical patent/BR112015003041A2/pt
Publication of BR112015003041B1 publication Critical patent/BR112015003041B1/pt

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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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BR112015003041-6A 2012-08-13 2013-08-13 Métodos de produção de compostos intermediários para síntese de 1-(2-desóxi-2-fluoro-4- tio-ss-d-arabinofuranosil)citosina e tionucleosídeo BR112015003041B1 (pt)

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JP2012-179380 2012-08-13
JP2012179380 2012-08-13
JP2013012693 2013-01-25
JP2013-012693 2013-01-25
PCT/JP2013/071871 WO2014027658A1 (ja) 2012-08-13 2013-08-13 １－（２－デオキシ－２－フルオロ－４－チオ－β－Ｄ－アラビノフラノシル）シトシンの合成中間体およびチオヌクレオシドの合成中間体ならびにそれらの製造法

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BR112015003041A2 true BR112015003041A2 (pt) 2018-05-29
BR112015003041B1 BR112015003041B1 (pt) 2022-07-26

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US (4) US9221865B2 (pt)
EP (2) EP2883866B1 (pt)
JP (2) JP5970550B2 (pt)
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